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July 31, 2025 20 mins

In this episode, Dr. JYP talks with Dr. Natalie Bath, M.D., a USA Health surgical oncologist, about a new groundbreaking cancer treatment for liver tumors called histotripsy. Histotripsy is a non-invasive technology that uses high-intensity sound waves to break up liver tumors without surgery, incisions or long recovery times. Patients go under general anesthesia, and the machine delivers sound waves to the cancer cells while the physician uses imaging to monitor the treatment. Most people go home the same day and recover quickly, needing only over-the-counter pain medication. This treatment works for different types of liver tumors, including those that have spread from other cancers, and it doesn’t require people to stop blood thinners. Histotripsy is FDA-approved for liver tumors and offers hope for patients who might not have other options. This episode encourages patients to ask their doctors about all possible treatments and to keep learning more about their choices.


3 Key Listener Takeaways

Groundbreaking, Non-Invasive Liver Cancer Treatment

The episode introduces histotripsy, an exciting new technology that uses focused ultrasound waves from outside the body to destroy liver tumors in a non-invasive manner. This innovative approach preserves surrounding liver tissue and offers an option for patients who might not be candidates for surgery.

 

Eligibility and Patient Benefits

Histotripsy can be used to treat both primary liver cancer and metastatic cancers from other sites. It's especially promising for patients who are not surgical candidates or who are on medications like blood thinners that would otherwise complicate surgery. With minimal recovery — often just a same-day or next-day discharge — patients experience less downtime and can continue other therapies, such as chemotherapy or immunotherapy, without interruption.

 

Expansion of Treatment Options and Ongoing Research

The episode highlights how histotripsy adds to the arsenal of cancer care, offering hope and additional options, especially for those who previously had few. It is FDA-approved for liver tumors, with ongoing research exploring its use for kidney, prostate, and pancreatic cancers. Patients are encouraged to advocate for themselves, ask about new technologies, and seek out multimodal therapies that combine traditional and emerging treatments for the best possible outcomes.



Show Overview
 

00:45 Introduction to histotripsy, a groundbreaking, non-invasive treatment for liver tumors

01:26 Meet Dr. Natalie Bath

02:20 First adopter in Alabama

03:15 What patients can expect

04:55 Who is a candidate?

07:49 Benefits of non-invasive treatment

10:45 FDA approved for liver tumors

15:05 Potential uses for histotripsy

16:45 Where to learn more

 

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