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June 23, 2025 59 mins

Dr. Christopher Estes just dropped some serious knowledge bombs in our latest episode that will change how you think about testosterone – and it's not what you expect. This isn't your typical "just inject testosterone" conversation.

Something alarming is happening to young men's health, and most doctors are completely missing it. Dr. Estes sees 30-something men walking into his clinic with testosterone levels of 100-150.
That's not "low for their age" – that's catastrophically deficient for ANY age.

In this episode, you'll discover:
✅ The "pyramid approach" to hormones that addresses root causes instead of just symptoms
✅ Why DHEA is the most overlooked hormone (and which test 90% of labs get wrong)
✅ The cortisol-testosterone connection that explains why stressed men can't build muscle
✅ Environmental toxins that are stealing testosterone from an entire generation
✅ The estrogen factor in men that nobody talks about (but could save your prostate)

Dr. Estes is a board-certified OB-GYN, trained at the University of Miami, has a master's in epidemiology, and brings both academic rigor AND functional medicine wisdom to the table.
He breaks down the science in a way that makes sense, debunks dangerous medical myths, and gives you actionable strategies you can implement immediately.

                                        {------Sponsors------}

StemRegen: http://www.stemregen.co/drstephen 
(Special Offer: Save 15% Using Code “SBPOD” At Checkout)

Approved Medical Sollutions: https://approvedmedicalsolutions.com/
(Non-licensed patients can use code “sbarrett” for a 10% discount.)

Trokie : https://trokie.com/pod/

Profound Health : https://profound-health.com/product-category/bioregulators/?aff=PODOF
(A Trusted Source for Natural & Synthetic Bioregulators)

Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.

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The Pod Of Inquiry is designed to empower you with knowledge. What happens from there is up to you. Your host, Dr. Stephen Barrett, has designed this show to take you down some very deep rabbit holes hopefully bringing you back out again, relatively unscathed, but cerebrally wicked enabling a better understanding of all things worthy of inquiry.

Timestamps: 

00:00 - Introduction & Episode Overview
01:15 - Host Introduction
02:07 - Dr. Estes Background
05:53 - Conventional vs. Functional Medicine Approach
09:00 - The 1941 Huggins & Hodges Study
12:44 - Women's Health Initiative Parallel
16:34 - Testosterone Beyond Sexual Function
17:28 - Sponsor Break (Stem Regen)
20:32 - Broader Health Benefits of Testosterone
21:56 - Low T Epidemic in Young Menn
24:27 - Environmental & Lifestyle Factors
29:23 - Cortisol-Testosterone Relationship
35:03 - DHEA: The Most Missed Factor)
39:35 - Sponsor Break (Clean Ketones)
42:09 - DHEA Testing & Clinical Experience
45:57 - Chronic Pain & Hormonal Health
48:52 - Free Testosterone & Sex Hormone Binding Globulin (SHBG)
53:59 - Estrogen Monitoring in Men
54:44 - Routes of Administration
56:18 - Closing Remarks

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