The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

Episodes

May 6, 2025 67 mins
Today, we're joined by Josh Tobin, member of technical staff at OpenAI, to discuss the company’s approach to building AI agents. We cover OpenAI's three agentic offerings—Deep Research for comprehensive web research, Operator for website navigation, and Codex CLI for local code execution. We explore OpenAI’s shift from simple LLM workflows to reasoning models specifically trained for multi-step tasks through reinforcement learning,...
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Today, we're joined by Nidhi Rastogi, assistant professor at Rochester Institute of Technology to discuss Cyber Threat Intelligence (CTI), focusing on her recent project CTIBench—a benchmark for evaluating LLMs on real-world CTI tasks. Nidhi explains the evolution of AI in cybersecurity, from rule-based systems to LLMs that accelerate analysis by providing critical context for threat detection and defense. We dig into the advantage...
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In this episode, Kelly Hong, a researcher at Chroma, joins us to discuss "Generative Benchmarking," a novel approach to evaluating retrieval systems, like RAG applications, using synthetic data. Kelly explains how traditional benchmarks like MTEB fail to represent real-world query patterns and how embedding models that perform well on public benchmarks often underperform in production. The conversation explores the two-step process...
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In this episode, Emmanuel Ameisen, a research engineer at Anthropic, returns to discuss two recent papers: "Circuit Tracing: Revealing Language Model Computational Graphs" and "On the Biology of a Large Language Model." Emmanuel explains how his team developed mechanistic interpretability methods to understand the internal workings of Claude by replacing dense neural network components with sparse, interpretable alternatives. The c...
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Today, we're joined by Maohao Shen, PhD student at MIT to discuss his paper, “Satori: Reinforcement Learning with Chain-of-Action-Thought Enhances LLM Reasoning via Autoregressive Search.” We dig into how Satori leverages reinforcement learning to improve language model reasoning—enabling model self-reflection, self-correction, and exploration of alternative solutions. We explore the Chain-of-Action-Thought (COAT) approach, which u...
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Today, we're joined by Drago Anguelov, head of AI foundations at Waymo, for a deep dive into the role of foundation models in autonomous driving. Drago shares how Waymo is leveraging large-scale machine learning, including vision-language models and generative AI techniques to improve perception, planning, and simulation for its self-driving vehicles. The conversation explores the evolution of Waymo’s research stack, their custom “...
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Today, we're joined by Julie Kallini, PhD student at Stanford University to discuss her recent papers, “MrT5: Dynamic Token Merging for Efficient Byte-level Language Models” and “Mission: Impossible Language Models.” For the MrT5 paper, we explore the importance and failings of tokenization in large language models—including inefficient compression rates for under-resourced languages—and dig into byte-level modeling as an alternati...
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Today, we're joined by Jonas Geiping, research group leader at Ellis Institute and the Max Planck Institute for Intelligent Systems to discuss his recent paper, “Scaling up Test-Time Compute with Latent Reasoning: A Recurrent Depth Approach.” This paper proposes a novel language model architecture which uses recurrent depth to enable “thinking in latent space.” We dig into “internal reasoning” versus “verbalized reasoning”—analogou...
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Today, we're joined by Chengzu Li, PhD student at the University of Cambridge to discuss his recent paper, “Imagine while Reasoning in Space: Multimodal Visualization-of-Thought.” We explore the motivations behind MVoT, its connection to prior work like TopViewRS, and its relation to cognitive science principles such as dual coding theory. We dig into the MVoT framework along with its various task environments—maze, mini-behavior, ...
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Today, we're joined by Niklas Muennighoff, a PhD student at Stanford University, to discuss his paper, “S1: Simple Test-Time Scaling.” We explore the motivations behind S1, as well as how it compares to OpenAI's O1 and DeepSeek's R1 models. We dig into the different approaches to test-time scaling, including parallel and sequential scaling, as well as S1’s data curation process, its training recipe, and its use of model distillatio...
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Today, we're joined by Ron Diamant, chief architect for Trainium at Amazon Web Services, to discuss hardware acceleration for generative AI and the design and role of the recently released Trainium2 chip. We explore the architectural differences between Trainium and GPUs, highlighting its systolic array-based compute design, and how it balances performance across key dimensions like compute, memory bandwidth, memory capacity, and n...
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Today, we're joined by Sergey Levine, associate professor at UC Berkeley and co-founder of Physical Intelligence, to discuss π0 (pi-zero), a general-purpose robotic foundation model. We dig into the model architecture, which pairs a vision language model (VLM) with a diffusion-based action expert, and the model training "recipe," emphasizing the roles of pre-training and post-training with a diverse mixture of real-world data to en...
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Today we’re joined by Victor Dibia, principal research software engineer at Microsoft Research, to explore the key trends and advancements in AI agents and multi-agent systems shaping 2025 and beyond. In this episode, we discuss the unique abilities that set AI agents apart from traditional software systems–reasoning, acting, communicating, and adapting. We also examine the rise of agentic foundation models, the emergence of interf...
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Today, we're joined by Chris Lott, senior director of engineering at Qualcomm AI Research to discuss accelerating large language model inference. We explore the challenges presented by the LLM encoding and decoding (aka generation) and how these interact with various hardware constraints such as FLOPS, memory footprint and memory bandwidth to limit key inference metrics such as time-to-first-token, tokens per second, and tokens per...
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Today, we're joined by Patricia Thaine, co-founder and CEO of Private AI to discuss techniques for ensuring privacy, data minimization, and compliance when using 3rd-party large language models (LLMs) and other AI services. We explore the risks of data leakage from LLMs and embeddings, the complexities of identifying and redacting personal information across various data flows, and the approach Private AI has taken to mitigate thes...
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Today, we're joined by Chip Huyen, independent researcher and writer to discuss her new book, “AI Engineering.” We dig into the definition of AI engineering, its key differences from traditional machine learning engineering, the common pitfalls encountered in engineering AI systems, and strategies to overcome them. We also explore how Chip defines AI agents, their current limitations and capabilities, and the critical role of effec...
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Today, we're joined by Abhijit Bose, head of enterprise AI and ML platforms at Capital One to discuss the evolution of the company’s approach and insights on Generative AI and platform best practices. In this episode, we dig into the company’s platform-centric approach to AI, and how they’ve been evolving their existing MLOps and data platforms to support the new challenges and opportunities presented by generative AI workloads and...
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Today, we're joined by Dan Jeffries, founder and CEO of Kentauros AI to discuss the challenges currently faced by those developing advanced AI agents. We dig into how Dan defines agents and distinguishes them from other similar uses of LLM, explore various use cases for them, and dig into ways to create smarter agentic systems. Dan shared his “big brain, little brain, tool brain” approach to tackling real-world challenges in agents...
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Today, we're joined by Byron Cook, VP and distinguished scientist in the Automated Reasoning Group at AWS to dig into the underlying technology behind the newly announced Automated Reasoning Checks feature of Amazon Bedrock Guardrails. Automated Reasoning Checks uses mathematical proofs to help LLM users safeguard against hallucinations. We explore recent advancements in the field of automated reasoning, as well as some of the ways...
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Today, we're joined by Arash Behboodi, director of engineering at Qualcomm AI Research to discuss the papers and workshops Qualcomm will be presenting at this year’s NeurIPS conference. We dig into the challenges and opportunities presented by differentiable simulation in wireless systems, the sciences, and beyond. We also explore recent work that ties conformal prediction to information theory, yielding a novel approach to incorpo...
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