The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

Episodes

Building the Internet of Agents with Vijoy Pandey - #737

June 24, 2025 • 56 mins
Today, we're joined by Vijoy Pandey, SVP and general manager at Outshift by Cisco to discuss a foundational challenge for the enterprise: how do we make specialized agents from different vendors collaborate effectively? As companies like Salesforce, Workday, and Microsoft all develop their own agentic systems, integrating them creates a complex, probabilistic, and noisy environment, a stark contrast to the deterministic APIs of the...
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LLMs for Equities Feature Forecasting at Two Sigma with Ben Wellington - #736

June 17, 2025 • 59 mins
Today, we're joined by Ben Wellington, deputy head of feature forecasting at Two Sigma. We dig into the team’s end-to-end approach to leveraging AI in equities feature forecasting, covering how they identify and create features, collect and quantify historical data, and build predictive models to forecast market behavior and asset prices for trading and investment. We explore the firm's platform-centric approach to managing an exte...
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Zero-Shot Auto-Labeling: The End of Annotation for Computer Vision with Jason Corso - #735

June 10, 2025 • 56 mins
Today, we're joined by Jason Corso, co-founder of Voxel51 and professor at the University of Michigan, to explore automated labeling in computer vision. Jason introduces FiftyOne, an open-source platform for visualizing datasets, analyzing models, and improving data quality. We focus on Voxel51’s recent research report, “Zero-shot auto-labeling rivals human performance,” which demonstrates how zero-shot auto-labeling with foundatio...
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Grokking, Generalization Collapse, and the Dynamics of Training Deep Neural Networks with Charles Martin - #734

June 4, 2025 • 85 mins
Today, we're joined by Charles Martin, founder of Calculation Consulting, to discuss Weight Watcher, an open-source tool for analyzing and improving Deep Neural Networks (DNNs) based on principles from theoretical physics. We explore the foundations of the Heavy-Tailed Self-Regularization (HTSR) theory that underpins it, which combines random matrix theory and renormalization group ideas to uncover deep insights about model trainin...
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Google I/O 2025 Special Edition - #733

May 28, 2025 • 26 mins
Today, I’m excited to share a special crossover edition of the podcast recorded live from Google I/O 2025! In this episode, I join Shawn Wang aka Swyx from the Latent Space Podcast, to interview Logan Kilpatrick and Shrestha Basu Mallick, PMs at Google DeepMind working on AI Studio and the Gemini API, along with Kwindla Kramer, CEO of Daily and creator of the Pipecat open source project. We cover all the highlights from the event, ...
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RAG Risks: Why Retrieval-Augmented LLMs are Not Safer with Sebastian Gehrmann - #732

May 21, 2025 • 57 mins
Today, we're joined by Sebastian Gehrmann, head of responsible AI in the Office of the CTO at Bloomberg, to discuss AI safety in retrieval-augmented generation (RAG) systems and generative AI in high-stakes domains like financial services. We explore how RAG, contrary to some expectations, can inadvertently degrade model safety. We cover examples of unsafe outputs that can emerge from these systems, different approaches to evaluati...
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From Prompts to Policies: How RL Builds Better AI Agents with Mahesh Sathiamoorthy - #731

May 13, 2025 • 61 mins
Today, we're joined by Mahesh Sathiamoorthy, co-founder and CEO of Bespoke Labs, to discuss how reinforcement learning (RL) is reshaping the way we build custom agents on top of foundation models. Mahesh highlights the crucial role of data curation, evaluation, and error analysis in model performance, and explains why RL offers a more robust alternative to prompting, and how it can improve multi-step tool use capabilities. We also ...
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How OpenAI Builds AI Agents That Think and Act with Josh Tobin - #730

May 6, 2025 • 67 mins
Today, we're joined by Josh Tobin, member of technical staff at OpenAI, to discuss the company’s approach to building AI agents. We cover OpenAI's three agentic offerings—Deep Research for comprehensive web research, Operator for website navigation, and Codex CLI for local code execution. We explore OpenAI’s shift from simple LLM workflows to reasoning models specifically trained for multi-step tasks through reinforcement learning,...
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CTIBench: Evaluating LLMs in Cyber Threat Intelligence with Nidhi Rastogi - #729

April 30, 2025 • 56 mins
Today, we're joined by Nidhi Rastogi, assistant professor at Rochester Institute of Technology to discuss Cyber Threat Intelligence (CTI), focusing on her recent project CTIBench—a benchmark for evaluating LLMs on real-world CTI tasks. Nidhi explains the evolution of AI in cybersecurity, from rule-based systems to LLMs that accelerate analysis by providing critical context for threat detection and defense. We dig into the advantage...
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Generative Benchmarking with Kelly Hong - #728

April 23, 2025 • 54 mins
In this episode, Kelly Hong, a researcher at Chroma, joins us to discuss "Generative Benchmarking," a novel approach to evaluating retrieval systems, like RAG applications, using synthetic data. Kelly explains how traditional benchmarks like MTEB fail to represent real-world query patterns and how embedding models that perform well on public benchmarks often underperform in production. The conversation explores the two-step process...
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Exploring the Biology of LLMs with Circuit Tracing with Emmanuel Ameisen - #727

April 14, 2025 • 94 mins
In this episode, Emmanuel Ameisen, a research engineer at Anthropic, returns to discuss two recent papers: "Circuit Tracing: Revealing Language Model Computational Graphs" and "On the Biology of a Large Language Model." Emmanuel explains how his team developed mechanistic interpretability methods to understand the internal workings of Claude by replacing dense neural network components with sparse, interpretable alternatives. The c...
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Teaching LLMs to Self-Reflect with Reinforcement Learning with Maohao Shen - #726

April 8, 2025 • 51 mins
Today, we're joined by Maohao Shen, PhD student at MIT to discuss his paper, “Satori: Reinforcement Learning with Chain-of-Action-Thought Enhances LLM Reasoning via Autoregressive Search.” We dig into how Satori leverages reinforcement learning to improve language model reasoning—enabling model self-reflection, self-correction, and exploration of alternative solutions. We explore the Chain-of-Action-Thought (COAT) approach, which u...
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Waymo's Foundation Model for Autonomous Driving with Drago Anguelov - #725

March 31, 2025 • 69 mins
Today, we're joined by Drago Anguelov, head of AI foundations at Waymo, for a deep dive into the role of foundation models in autonomous driving. Drago shares how Waymo is leveraging large-scale machine learning, including vision-language models and generative AI techniques to improve perception, planning, and simulation for its self-driving vehicles. The conversation explores the evolution of Waymo’s research stack, their custom “...
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Dynamic Token Merging for Efficient Byte-level Language Models with Julie Kallini - #724

March 24, 2025 • 50 mins
Today, we're joined by Julie Kallini, PhD student at Stanford University to discuss her recent papers, “MrT5: Dynamic Token Merging for Efficient Byte-level Language Models” and “Mission: Impossible Language Models.” For the MrT5 paper, we explore the importance and failings of tokenization in large language models—including inefficient compression rates for under-resourced languages—and dig into byte-level modeling as an alternati...
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Scaling Up Test-Time Compute with Latent Reasoning with Jonas Geiping - #723

March 17, 2025 • 58 mins
Today, we're joined by Jonas Geiping, research group leader at Ellis Institute and the Max Planck Institute for Intelligent Systems to discuss his recent paper, “Scaling up Test-Time Compute with Latent Reasoning: A Recurrent Depth Approach.” This paper proposes a novel language model architecture which uses recurrent depth to enable “thinking in latent space.” We dig into “internal reasoning” versus “verbalized reasoning”—analogou...
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Imagine while Reasoning in Space: Multimodal Visualization-of-Thought with Chengzu Li - #722

March 10, 2025 • 42 mins
Today, we're joined by Chengzu Li, PhD student at the University of Cambridge to discuss his recent paper, “Imagine while Reasoning in Space: Multimodal Visualization-of-Thought.” We explore the motivations behind MVoT, its connection to prior work like TopViewRS, and its relation to cognitive science principles such as dual coding theory. We dig into the MVoT framework along with its various task environments—maze, mini-behavior, ...
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Inside s1: An o1-Style Reasoning Model That Cost Under $50 to Train with Niklas Muennighoff - #721

March 3, 2025 • 49 mins
Today, we're joined by Niklas Muennighoff, a PhD student at Stanford University, to discuss his paper, “S1: Simple Test-Time Scaling.” We explore the motivations behind S1, as well as how it compares to OpenAI's O1 and DeepSeek's R1 models. We dig into the different approaches to test-time scaling, including parallel and sequential scaling, as well as S1’s data curation process, its training recipe, and its use of model distillatio...
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Accelerating AI Training and Inference with AWS Trainium2 with Ron Diamant - #720

February 24, 2025 • 67 mins
Today, we're joined by Ron Diamant, chief architect for Trainium at Amazon Web Services, to discuss hardware acceleration for generative AI and the design and role of the recently released Trainium2 chip. We explore the architectural differences between Trainium and GPUs, highlighting its systolic array-based compute design, and how it balances performance across key dimensions like compute, memory bandwidth, memory capacity, and n...
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π0: A Foundation Model for Robotics with Sergey Levine - #719

February 18, 2025 • 52 mins
Today, we're joined by Sergey Levine, associate professor at UC Berkeley and co-founder of Physical Intelligence, to discuss π0 (pi-zero), a general-purpose robotic foundation model. We dig into the model architecture, which pairs a vision language model (VLM) with a diffusion-based action expert, and the model training "recipe," emphasizing the roles of pre-training and post-training with a diverse mixture of real-world data to en...
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AI Trends 2025: AI Agents and Multi-Agent Systems with Victor Dibia - #718

February 10, 2025 • 104 mins
Today we’re joined by Victor Dibia, principal research software engineer at Microsoft Research, to explore the key trends and advancements in AI agents and multi-agent systems shaping 2025 and beyond. In this episode, we discuss the unique abilities that set AI agents apart from traditional software systems–reasoning, acting, communicating, and adapting. We also examine the rise of agentic foundation models, the emergence of interf...
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