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April 2, 2025 17 mins

The provided sources explore diverse aspects of hormonal influences and potential interventions in various health conditions. One study investigates the impact of **3,3′-diindolylmethane (DIM)** on estrogen metabolism in patients with thyroid proliferative disease. Another examines the effectiveness of a **proprietary blend of pomegranate and cocoa extracts** in alleviating symptoms of aging in males, focusing on perceived stress and safety parameters. Several sources discuss **testosterone levels in men**, including the effects of aging and exercise, and the potential of **aromatase inhibition** to restore these levels in older men with hypogonadism. Lastly, one article reviews the role of **black pepper extract (Bioperine®)** as a bioavailability enhancer for iron supplementation, particularly in physically active individuals, to combat iron deficiency and improve athletic performance.


Various Factors May Modulate the Effect of Exercise on Testosterone Levels in Men


Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis


Aromatase inhibitors in men: effects and therapeutic options


Testosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters


Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels


Aromatase inhibition restores testosterone levels in hypogonadal older men


Structural and Functional Characterization of Aromatase, Estrogen Receptor, and Their Genes in Endocrine-Responsive and – Resistant Breast Cancer Cells


Testosterone and Sarcopenia


Aromatase Inhibitors in Erectile Dysfunction



Sleep, Rhythms, and the Endocrine Brain: Influence of Sex and Gonadal Hormones

https://www.ncbi.nlm.nih.gov/…articles/PMC6987613/

https://eje.bioscientifica.co…ls/eje/169/5/705.xml


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897047/

https://pubmed.ncbi.nlm.nih.gov/24928451/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805471/

https://www.ncbi.nlm.nih.gov/books/NBK92772/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975356/

https://pubmed.ncbi.nlm.nih.gov/1901550/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287254/

https://pubmed.ncbi.nlm.nih.gov/10442580/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667256/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1476110/

https://www.medsci.org/v19p1290.htm

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048776/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073592/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353321/

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