a16z Talent x Opportunity Startup Hotline

a16z Talent x Opportunity Startup Hotline

You’ve got startup questions. We’ve got answers. Introducing the TxO Startup Hotline series–where ‪Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz, breaks down real founder questions and shares the game plan to help you build, scale, and win. From making the leap to full-time founder to unlocking your first investor check– we’re covering it all. Call 1-844-DIAL-TXO to share your questions and you might be featured on the show.

Episodes

August 5, 2025 4 mins

This week’s episode gets into the emotional side of entrepreneurship—and how to keep your relationship steady while chasing your startup dream. Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz answers one founder’s question,

“My partner is pretty risk-averse and not necessarily supportive of my entrepreneurial goals. They’d prefer I keep a stable 9–5. Any tips on how to navigate this?”

Whether your emotion...

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How do you know when it’s time to make your first hire?

In episode 6 of the TxO Startup Hotline, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz, is joined by Jenna Zucker, Talent Partner at Andreessen Horowitz to answer one founder’s question:

“When should I begin to think about hiring additional team members? Should I continue with contractors or look at full-time hires?”

Jenna breaks down:

When to hire c...

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What do early-stage investors really want to see?

In episode 5 of the TxO Startup Hotline, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz, answers one of the most common questions founders ask when looking to raise capital:

“What are the exact things an investor needs to see from my business to invest at an early stage?”

Kofi breaks down the key signals investors look for before writing that first check –...

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Struggling to find the right cofounder for your startup?

In episode 4 of the TxO Startup Hotline, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz, answers a question many solo founders wrestle with:

“How do I find a cofounder – and what should I look for in the right person?”

Drawing from his own founder journey, Kofi shares:

How to clarify what kind of cofounder you actually need

Ways to expand your network...

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July 27, 2025 3 mins

Worried someone might steal your startup idea?

In episode 3 of the TxO Startup Hotline, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz is joined by Allison Cooper, partner of the startup and venture practice at Fenwick, to answer this founder’s question:

“If I have a shared business idea with a friend, but they don’t want to pursue it, could they still take credit or ownership later on?”

Kofi and Allison ...

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Not sure which funding path is right for your startup? In this episode of the TxO Startup Hotline series, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz answers the question:

“What are the different types of funding options including venture capital? How do I determine which is right for my company?”

 

Kofi breaks down key considerations and paths for startup funding, including:

The pros and cons of bootst...

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Thinking about quitting your job to go full-time on your startup? You’re not alone. In this episode of the Talent x Opportunity Startup Hotline series, Kofi Ampadu, partner and head of Talent x Opportunity at Andreessen Horowitz answers the question:

"How do I know if I’m ready to quit my full-time job and take the plunge full-time into my business? Even though it doesn’t seem sustainable to keep this as a side hustle, I’m nervous a...

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