Adverse Reactions
An interview podcast bringing you the people and stories behind the science of how biological, physical, and chemical agents may cause adverse reactions to public, animal, and environmental health. This podcast is presented by the Society of Toxicology (SOT) and hosted by SOT members Anne Chappelle and David Faulkner. About Anne After graduating from the University of Delaware with a BS in biology in 1991, Anne Chappelle accidentally found her calling when she worked a gap year in an industrial toxicology laboratory. As it turned out, toxicology was the perfect marriage of protecting both human health and the environment. She then went on to receive her PhD in pharmacology and toxicology from the (now) University of the Sciences in Philadelphia in 1997, focusing on upper respiratory tract toxicity. For the last 20+ years, as a toxicologist and risk assessment expert for the chemical industry, Anne has been thrilled to not work in a laboratory anymore. Along the way, she has added a few more titles: spouse; DABT; Principal of Chappelle Toxicology Consulting, LLC; occasional blogger at My Toxic Life; and most life changing (and expensive): Mom. She is thrilled to be partnered with David to add podcast co-host to the list because it gives her the opportunity to “channel my inner Terry Gross.” About David David Faulkner’s interest in science started at age five with a few Bill Nye the Science Guy VHS tapes and hasn’t diminished since. A lifelong artist and science fan, David has worked in nearly every mass communication medium to share his love of science with the world. Now, as an early career toxicologist, David is living out his dream of co-hosting a science podcast! With a budget! And a producer! And super cool guests! And an awesome co-host! David thinks Bill would be proud. David attended the University of Michigan, where he completed a BS in microbiology, a BA in English language (emphasis in creative writing), and an MPH in environmental health sciences, and the University of California Berkeley, where he completed a PhD in molecular toxicology under the supervision of Dr. Chris Vulpe. He has held postdoctoral appointments at the Berkeley Center for Green Chemistry and the Lawrence Berkeley National Laboratory and just started a new position as a toxicological risk assessor. He also is a full-time parent to two adorable purple velvet plants: Planthony Bourdain and Marie Planthoinette. Disclaimer The viewpoints and information presented in Adverse Reactions represent those of the participating individuals. Although the Society of Toxicology holds the copyright to the production, it does not vet or review the information presented nor does presenting and distributing the Adverse Reactions podcast represent any proposal or endorsement of any position by the Society.
Episodes
From studying polluted waters off the coast of California to explaining the feasibility of a fungal-based zombie outbreak at San Diego Comic Con, Kari Sant, PhD, Michigan State University, discusses her passion projects with co-hosts Anne Chappelle, PhD, DABT, and David Faulkner, PhD, DABT. Dr. Sant also reveals what it is like to start a new lab when you change institutions.
About the Guest
Kari Sant, PhD, is an Assoc...
Noah Whiteman, PhD, a professor at UC Berkeley, shares his unique perspective on toxins, stemming from his background in entomology and plant-insect interactions. He explores how toxins impact the ecology and evolution of various organisms, from insects to humans, with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.
About the Guest
Noah Whiteman, PhD, is Professor of Genetics, Genomics, Evolution, and Developmen...
Sometimes negative results can be just as interesting as positive ones. Nivetha Subramaniam, a student at McGill University, discusses her research regarding the potential cardiovascular risks from exposure to mixtures of arsenic and cadmium with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD.
About the Guest
Nivetha Kamalavannan Subramaniam is a PhD student at McGill University in Canada. She is the recipient o...
From Superfund remediation sites near neighborhoods to wartime combat zones, toxicology is everywhere, which is why many states employ toxicologists on their public health teams. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, speak with Julie Miller, PhD, Public Health Toxicologist for the Commonwealth of Pennsylvania, about the impacts of stress and environmental exposures on public health.
About the Guest
Jul...
Did you know that there are scientists who study teamwork? Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, DABT, speak with Stephen Fiore, PhD, Director, Cognitive Sciences Laboratory, about the art and science of working in teams and what you can do to improve teamwork in your lab, department, etc.
About the Guest
Stephen M. Fiore, PhD, is Director, Cognitive Sciences Laboratory, and Professor with the Universi...
Fish on treadmills? Lisa Truong, PhD, MBA, Oregon State University, discusses the unique ways that they test exposure effects using zebrafish. Co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, also ask her about the benefits of having an MBA as a scientist.
About the Guest
The overall goal of Lisa Truong's research program is to utilize the zebrafish model to help build computational predictive toxicity model...
Can two people experience the same exposure and have different reactions to both chemical and non-chemical stressors? Yes, according to Samantha "Sam" Snow and a team of toxicologists, epidemiologists, exposure scientists, and others who assess risk. Dr. Snow talks with co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, about exposure science, new approach methodologies, and forming the SOT Out Toxicologists and Allie...
Whether its found in nature or composed by chemists a sweetener undergoes the same evaluations, according to Corey Scott, PhD, Principal Nutritionist, Cargill. Dr. Scott explains to co-hosts Anne Chappelle, PhD, and David Faulkner, PhD, how all sweeteners must be able to replace multiple properties inherit in sugar, such as taste, nutritional content, and binding properties.
About the Guest
Corey Scott, PhD, is a Princ...
Co-hosts Anne Chappelle and David Faulkner speak with William J. Sullivan, PhD, Showalter Professor of Pharmacology & Toxicology and Professor of Microbiology & Immunology with the Indiana University School of Medicine, about toxic parasites lying dormant in your brain and the power and importance of science communication.
About the Guest
Bill Sullivan, PhD, has been studying the intracellular parasite Toxoplas...
As the foremost experts on the effects of chemicals, biological substances, and more, toxicologists are key contributors to health regulation and laws. Law Professor and lawyer Claudia Polsky, University of California Berkeley, discusses how science can influence environmental health law, as well as environmental justice, with co-hosts Anne Chappelle and David Faulkner and reveals legal gaps in protecting public health.
Ab...
While pharmaceuticals provide positive benefits for patients, what about workers that may be exposed during production? Elizabeth M. Vancza, Merck & Co. Inc., reveals to co-hosts Anne Chappelle and David Faulkner the role of occupational toxicologists in understanding the exposure risks of pharmaceuticals, chemicals, and other substances that may affect worker health, as well as how to protect them from these exposures.
Nanoparticles are manmade fibers, particulates, and other objects that are so small that when inhaled, they can escape the lungs and enter other body systems. Timothy Nurkiewicz, West Virginia University, studies the effects of these and other particulars. He discusses his inhalation and nanotoxicology research, as well as work with the National Guard on developing facemasks to protect against airborne diseases, with co-hosts Anne ...
Blood samples and health records for 15,000 pregnancies provides a wealth of scientific data. Add samples and records from the resultant children and grandchildren, and you have an invaluable cohort with which you can study the long-term results of events that occur during pregnancy. Barbara Cohn with the Public Health Institute is the Director of such a cohort and discusses it with co-hosts Anne Chappelle and David Faulkner, inclu...
The fields of epidemiology and toxicology sometimes find themselves at odds, but Gradient’s Julie Goodman, an epidemiologist and toxicologist, shares how the two disciplines can complement each other to evaluate public health risks. Dr. Goodman also dives into the finer points of systemic reviews and meta-analyses in her conversation with co-hosts Anne Chappelle and David Faulkner.
About the Guest
Julie E. Goodman, PhD...
When it comes to hormones, everyone has them all, but their levels are where things get interesting. How chemicals affect estrogen signaling in the brain is the research focus of Troy Roepke, Rutgers, who talks to co-hosts Anne Chappelle and David Faulkner about how gender is not easily defined biologically, what it is like to be a “fabulously queer” professor, and how science can better serve the LGBTQ+ and other marginalized comm...
Since the discovery of cannabinoid receptors in the mid-1990s, researchers have been trying to determine their role and how they affect the immune system. Barbara Kaplan, Mississippi State University, discusses research in this area with co-hosts Anne Chappelle and David Faulkner and also shares what scientists are discovering about CBD, vaping, THC, and more.
About the Guest
Barbara Kaplan, PhD, is an Associate Profes...
Because of natural exposure to wildfire smoke, nonhuman primates have provided an increased understanding of the long-term effects of smoke inhalation during infancy, shares Lisa Miller, University of California Davis (UC Davis). Dr. Miller also discusses with co-hosts Anne Chappelle and David Faulkner the importance of animal models in human health research and how nonhuman primates can be good models for vaccine testing, as was t...
With nonalcoholic fatty liver disease affecting nearly a third of the US population, Luma Melo, University of Pittsburgh, describes how mouse studies have shown that low-impact exercise can help reverse liver damage. Dr. Melo also shares with co-hosts Anne Chappelle and David Faulkner how research funding works in her native Brazil and the role of Brazilian women in toxicology.
About the Guest
Luma Melo, PhD, University of Pitt...
While no longer national news, the Deepwater Horizon oil spill is still impacting the ecological health of the Gulf of Mexico and the livelihoods of the communities that rely upon the gulf’s aquatic life, as Robert “Joe” Griffitt of the University of Southern Mississippi reveals. Dr. Griffitt and co-hosts Anne Chappelle and David Faulkner discuss how ecotoxicology is both an applied and a basic science, as well as how scientific di...
How human activity, chemical exposures, and environmental factors combine to contribute to wildlife population declines is at the forefront of the research by Dr. Caroline Moore and other teams at the San Diego Zoo Wildlife Alliance. Dr. Moore unravels the role of toxicology in wildlife conservation with co-hosts Anne Chappelle and David Faulkner.
About the Guest
Caroline Moore, PhD, DVM, serves the San Diego Zoo Wildlife Allia...
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