May 7, 2025 • 59 mins
Ozempic Side Effects? Plastic Surgeons Reveal Truth About "Ozempic Butt" & Extreme Weight Loss Risks
What really happens after major weight loss with Ozempic or GLP-1 meds? These top plastic surgeons and doctors aren’t guessing—they’ve treated the aftermath firsthand.
From “Ozempic face” to loose skin and surprising muscle loss, they’ve seen it all. In this episode, they break down the untold side effects, the rising demand for surgery, and the deeper impact these drugs are having on patients' bodies—and confidence.
But it’s not just warnings.
They also unpack:
- Why some transformations look amazing—and others don’t
- What mistakes people make when starting GLP-1s
- A smarter approach to preserving your body as the weight drops
- The next wave of meds everyone’s whispering about (and whether they’re any better)
If you’re considering GLP-1s—or already on them—watch this first. These are the voices behind the scenes, telling the truth no one else is saying.
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:19):
so latest, latest, uh viral trends going on?
Uh, I have no clue, but I'veheard about this ozempic.
But what do you guys thinkabout the ozempic?
But do people get ozempic eyes?
Speaker 2 (00:33):
uh, they, they can't do.
You lose some fat in the eyesactually there.
Speaker 1 (00:38):
There's stuff about people that can like right after
they start ozempic.
Especially as we age, peopleget like blurred vision right
after because the blood sugarsare moving around a lot but.
Speaker 2 (00:51):
But like, how about the lower eyelids?
Do do they get more saggy, ordo do they?
Do they get more deflated?
Speaker 3 (00:58):
so why do you ask about?
That is what's behind theeyelid.
What do most?
Speaker 2 (01:02):
people see yeah, yeah , we go and take fat out, right,
yeah, does that fat shrink ever?
Or is that fat that that'sprobably like one of the last
things to shrink, right?
Speaker 1 (01:11):
yeah, so the fat's gonna be there from previously
and probably after a zempic,because they lose a little uh,
probably the.
They lose weight and then theskin becomes more lax, so it
probably becomes bigger.
Yeah, probably bigger fat padsthere.
Speaker 2 (01:28):
Yeah.
Speaker 1 (01:30):
Then more people would probably look towards a
lower blepharoplasty, which istaking the excess skin from the
lower eyelids and removing thefat.
Speaker 2 (01:38):
Yeah, so ozempic butt , yeah, it's a real thing and
it's more than just ozempic butt.
Me and Rods have been doingmore and more eight, 10 hour
cases because people haveOzempic arms, Ozempic legs, uh,
Ozempic everything.
Speaker 1 (01:52):
There's.
Speaker 2 (01:52):
Ozempic body, yeah, ozempic body where they've lost
all this weight.
Now there's the excess skin andfor them to build the
confidence and get back into thenormal daily activities.
It's tough when you're havingto put on Spanx to go and lift
and you're not seeing theresults on the scale still.
You know you can't really keepon going up on Ozempic or any of
(02:15):
these GLP-1s because whatthat's going to do is you're
going to just continue on losingmuscle mass as well as, like
fat mass.
But overall going up in dosageisn't going to help you much.
You want to maintain the dosage, just eat more protein and keep
the um, keep the muscle andozempic, but not are you just
(02:37):
losing weight and the skinsagging, but you're also going
to lose some muscle mass.
So you know you got to continueon doing squats and your
resistance exercises with thatto kind of like if you're having
surgery to help these thingsout, you also want to kind of
continue on building that muscle, right, Whatever you say.
Speaker 3 (02:58):
Yeah, definitely Like , cause you'll, you'll drop.
You'll definitely drop musclemass if you don't do anything,
if you sit around.
But it's like they're saying oh, people are coming out with
ozempic butt, ozempic face.
That's kind of why you'retaking the medication right, you
actually want that.
So if you actually get ozempicbutt or ozempic face, that's
(03:19):
just telling you you have weightloss.
Those are your fat pockets.
And now those fat pockets aredeflating and once that's
deflating, the skin sags.
That's just classic signs ofaging.
Right, like during training,they're like these are classic
signs of your facial aging.
It's like it's plump.
Your, your face is like ovaland then like it gradually drops
(03:41):
down with age.
Same thing happens if you gainweight and then drop a bunch of
weight.
Speaker 2 (03:46):
It's going to sag and whether it's your face, your
butt, Just like when I had like23-inch arms and I thought I was
huge.
Then I lost all that weight andmy skin's like what's that
stretch arm strong?
Speaker 3 (03:57):
This can stretch out to 23 inches.
You know that much.
Speaker 2 (04:01):
Yeah, I take semaglutide, take I take
semaglutide.
I've taken semaglutide.
I take terzeptide.
I take red true tide.
Do I have ozempic?
But my wife would probably sayno, because I never had a butt
to get ozempic, but so you gotto really have a butt to
actually lose it, but you wearspanks to work uh, no, he wears
sometimes sometimes
Speaker 1 (04:26):
I wear more leg warmers.
Speaker 2 (04:27):
But it's kind of like , yeah, it keeps my butt up I
have heard.
Speaker 3 (04:32):
I have heard uh on different like podcasts, youtube
videos and stuff.
People are afraid to lose theirmuscle mass and uh, bone
density density as a side effectfrom taking Ozempic or GLP-1,
whether it's Manjaro OzempicWegovy.
But how can you prevent that ordiminish that?
Speaker 2 (04:59):
You really can't prevent it because, no matter
what, you're decreasing calorieintake, so that's going to
decrease it.
You're also decreasing theamount of weight and stress on
your bones, so that decrease,decrease weight is also going to
decrease the amount of musclesand stuff you need to carry that
extra 10, 20, 30 pounds.
Speaker 3 (05:19):
That you know what also does that if you get sent
out to the space station and youget stuck there for eight
months for political reasons.
You're going to lose bonedensity and muscle mass.
Speaker 2 (05:30):
But maybe everyone needs to wear a weighted jacket,
like a lot of these people dothese days just to simulate that
extra weight being on them sowhen they're walking around
daily.
Speaker 3 (05:41):
that actually benefits you in multiple ways
anyhow, but is the uh, like thethe bone density and skeletal
muscle mass lost relative tooverall weight proportional, or
are they losing more?
Like, let's say, more bone massand skeletal muscle mass
compared to overall mass?
Speaker 2 (06:01):
it's patient dependent.
You know I've been on it for, Ithink, almost three years and
you know, like that first sixmonths I probably lost a lot of
weight and I lost muscle mass.
But after that six months I'vegained muscle mass and kind of
kept at the same weight.
And, like you know, I microdoseand like change dosing, like
when I go on vacation and stufflike sometimes to get cut up and
(06:25):
sometimes you know, and youknow, just play around with a
dosing.
But I've always put on moreskeletal muscle mass over the
past two years.
That first six months was theonly time I think I lost a
little bit of the muscle massand the thing is like increasing
protein and I wasn't reallyworking out that first six
(06:45):
months but once the weight cameoff I started working out and I
think that kind of like.
Also, you know you can't live asedentary lifestyle.
I think you're going to, um,just lose, uh.
Speaker 3 (06:59):
Oh yeah, asking for like a chemical way to starve
yourself?
Yeah, that makes sense, I'mgoing to start it.
I've been saying it for like ayear I starve yourself.
Yeah, that makes sense, I'mgonna start it.
I've been saying it for like ayear I just want to see the
difference.
But I've you saw, I sent you thein-body results.
I'm actually able to get downmy body fat percentage yeah,
nowhere near what I wanted andincrease my skeletal muscle mass
.
I actually wanted to increasemy skeletal muscle mass to about
(07:23):
like two more pounds than whereit is right now.
It's already up like fourpounds, yeah, but then get on
some terzapatide yeah, so thensee how lean I can get.
Yeah, with like small doses,but not but like.
Speaker 2 (07:36):
Also, the other thing that people don't look at is
like optimizing your hormones,like, yeah, your your
testosterone um and also yourthyroid hormone, you know, like
just optimizing those.
You'll also need a lower doseof your glp-1s um to be able to
maintain your muscle mass andlose weight and have the energy
(07:58):
to go work out and be focusedand get on with daily activities
.
Instead of, like you know,people are like, oh, glp ones
are going to cause me to betired and I don't want to do
anything, but they're becauseyou're taking them the wrong way
.
If you're taking them withappropriate vitamin and
nutrition and like with abalance lifestyle changes that
(08:20):
you know that appropriatephysicians will lead you the
right way instead of you know,yeah, you could pay someone like
99 bucks a week or 99, howevermuch of your pain, and they're
just handing you the medicationand telling you unless you're
self-motivated, which usuallyaren't, that's why you're on
these medications, You're you'renot going gonna get to the
(08:43):
point you really want to andyou're never going to be able to
come off of them or be likemicro dosing just for health
purposes.
Yeah, because you're.
You're still living that samelifestyle that as soon as you
come off of them, you're goingto eat bad stuff and not work
out, and it you know.
Speaker 3 (09:01):
You it or you get off because you're craving that
stuff.
Speaker 2 (09:04):
You're like, ah, I want to eat some more cake now.
Yeah, so I'm going to this.
Speaker 3 (09:10):
This thing prevents me from wanting to eat more cake
.
Speaker 2 (09:12):
Yeah, I find like, as I lowered my dose, like I was
shopping more frequently online.
Whatever I wanted, I was buyingonline.
Speaker 3 (09:21):
Really, it's seriously when you lower your
dose.
When I lowered, yeah, there'sdefinitely some effect, because
I started.
Speaker 2 (09:28):
I started like doing it once every two, three weeks
and I felt like, yeah, I wasdefinitely.
I was like, all right, I needto up my dose a little bit.
Speaker 3 (09:35):
I'm buying too much.
So if your wife's buying toomuch, stuff online yeah, that's
a good, good indication to getsome.
Speaker 2 (09:44):
You can offer a nice massage and just rub it in.
Yeah, quick little shot.
It won't hurt nobody Do we wantto see the video and go from.
Speaker 3 (09:54):
Yeah, what video are we watching?
Speaker 2 (09:57):
Dr Mike was talking about Ozempic butt.
Speaker 6 (09:59):
I don't want to exercise, I'll just take Ozempic
.
That's the thing I'm sureyou're aware of, like Ozempic
butt or whatever, wherehousewives who had no interest
in resistance training orbuilding muscularity, no
interest in controlling theirdiets or eating healthier, they
just take a crapload of Ozempicand they're like oh, I've lost a
ton of weight, but now I'msarcopenic.
That's definitely a bad outcome, but I would say that's more of
(10:19):
a slight misapplication ofpharmaceutical technology, and
there is such a thing as properapplication and I think in the
end we'll have a cocktail ofdrugs that are increasingly
better at doing things,increasingly lower risks and
downsides.
I think that's a world we wantto live in.
Speaker 3 (10:36):
Which one's Dr Mike with glasses, one's a real
doctor, is he a?
Chiropractor?
No, he's a physical therapistor like exercise physiologist.
I listened to him on a podcast,yeah, and it sounds like he
knows what he's talking about.
It's like, oh yeah, best way togain strength is probably based
on some research.
I didn't even look it up.
It's like going to like max,like range.
Speaker 2 (11:01):
Yeah.
Speaker 3 (11:02):
And light reps Light reps make a lot of sense to me
and max range light reps make alot of sense to me and max range
like extending the musclefibers makes sense to me too.
But I swear that next day Iwent and did like deep squats
yeah, my back hurt like fuckinghell.
Like I was like ah, I knew Ishouldn't have fucking done that
.
Like I'm not building muscleCause my muscle, my fucking back
(11:24):
hurts.
Speaker 2 (11:24):
But.
But like the, the way to umwork out, like with the
resistance bands and theresistance bands, you're doing
high reps, it's not very highweight, and what you're doing is
you don't want to lock out atall, you want to go, you want to
keep the ranges in betweenwhere you're going up and down,
so your muscles are alwaysengaged.
Speaker 3 (11:44):
I might have misunderstood them, yeah, but it
was pretty much saying kind oflike what?
Corley tells us like yeah oh,you gotta range out with like
the squats go like, and it'sjust like you know what.
Maybe I don't need to do thatyeah, I don't um, I'm not trying
to get that strong no, um.
Speaker 2 (12:02):
Well, you know you gotta slowly, like what corley
was saying.
You gotta kind of slowly getthere because you know your
ankles kind of stiffen up quitea bit pretty quickly.
Speaker 3 (12:14):
So you gotta get them on here.
Speaker 2 (12:16):
That would actually be hilarious I know he listens
to a lot especially if you starttalking about black rights
activists and stuff.
Speaker 3 (12:24):
A whole mix of things Deep squats versus DI yeah.
Speaker 2 (12:29):
And why you need to do explosive exercises.
For a lot of you'll needexplosiveness in your life.
Speaker 3 (12:39):
As an anesthesiologist, I was going to
just ask.
Speaker 2 (12:45):
I've been going lower carbs.
Speaker 3 (12:49):
I've been eating raw eggs.
Do I need to worry aboutanything about the bird flu
going on?
Speaker 2 (12:55):
No, because they killed off a lot of eggs.
Speaker 1 (12:58):
Yeah, they shouldn't be.
It shouldn't reach me right?
No, I don't think so.
Speaker 3 (13:02):
Okay, because I don't want to take the time to cook
the eggs.
It's so much easier.
Speaker 2 (13:06):
But does it matter if you cook it or not?
With the bird flu, I don't know.
I don't think it matters.
That's why they took it off theshelf.
Speaker 3 (13:14):
They said most ways of contracting bird flu is
coming in contact with it.
Speaker 4 (13:25):
So at least like three to eight people have
gotten bird flu before I do.
Speaker 2 (13:28):
Do you need a Fauci vaccine if you get it?
So what happens if you get thebird flu?
You might die.
Speaker 3 (13:34):
Oh yeah, that's why I'm asking you.
Speaker 1 (13:41):
You guys are clearly the wrong.
Can you get bird flu throughLike?
Is it oral?
Speaker 3 (13:46):
Through contact.
I don't know they got rid ofall those eggs.
No but like could you eat birdflu Can?
Speaker 1 (13:51):
it be fecal-oral Not fecal-oral necessarily.
Speaker 3 (13:56):
Not everything has to be fecal-oral.
Speaker 1 (14:01):
I mean that's one of the routes I'm talking about
eggs.
Speaker 3 (14:04):
I'm not talking about shit.
I'm not talking about shit.
Speaker 6 (14:06):
I'm not eating shit, yeah, but.
Speaker 2 (14:08):
Well those chickens are shitting those eggs out.
Speaker 3 (14:11):
But I don't literally eat shit, I don't think.
No, it said contact with birds.
Speaker 2 (14:16):
So, it's usually the bird farmers that, get it, but
like what happens with the eggsthat they had to kill off all
those eggs?
Speaker 3 (14:25):
It's just the chickens passing the shit around
themselves, so okay.
Speaker 2 (14:30):
So killing off the eggs isn't going to pass the
Eating undercooked eggs oh yeah,is that?
Speaker 3 (14:35):
number one.
I'll hold off on that.
Speaker 1 (14:39):
Number one is contact with infected birds of course.
Speaker 2 (14:42):
What does it give you ?
Does it give you diarrhea?
Speaker 3 (14:45):
No, you can fucking die.
It's scary shit.
If it was just like a little,you know me and diarrhea I'm
cool with.
Like I'm not going to die ofdiarrhea.
I'm in the developed world.
Speaker 1 (15:00):
I'll give you guys a death rate for bird flu in a
second.
See what AI tells us.
I'll give you guys a death ratefor bird flu in a second.
See what AI tells us.
Wait, what was this?
Speaker 3 (15:09):
episode about oh shit .
Speaker 4 (15:14):
And while okay, so yeah, Close contact with
infected birds or contaminatedenvironments.
Speaker 1 (15:19):
While the risk of human-to-human transmission is
low, the mortality rate forknown human cases is around 50%.
Oh shit, you can die.
You can die.
One out of two die.
Speaker 2 (15:31):
It's like people that get it are probably like pretty
sick people.
Speaker 1 (15:35):
Yeah, they're knee-deep in birds.
Speaker 3 (15:36):
Yeah, we're talking about these farms with like
thousands and thousands ofchicken in them.
Speaker 2 (15:43):
Yeah, you probably get like freakingicking high
dose of bird flu.
Speaker 3 (15:47):
I'm just picturing Napoleon Dynamite tending to
chicken.
Speaker 1 (15:52):
Speaking about explosive exercises oh exercise.
I was like, oh, you got theright guy, I know exactly
everything about explosivediarrhea.
Speaker 2 (16:03):
Me too, me too.
But okay, let's think of thechat.
Well, eat at chamber.
Speaker 1 (16:08):
The last three months I've gotten the first two food
poisonings of my life.
Speaker 2 (16:12):
Dude you guys scared the crap out of me Like I won't
even eat fruit at that place.
Speaker 1 (16:17):
I know I look and I'm like, oh, that's a salad bar.
I don't know if I could.
I'm going to go grab the saladfrom the fridge I'm gonna
probably at least it's in thefridge.
And then he says, ah, nevermind, I'll take the meatloaf no,
my buddy and uh, my collegeroommate used to he always be
like, yeah, you gotta doexplosive exercises, he's like.
(16:40):
He's like you gotta be ready ifthe apocalypse happens, you
gotta be ready.
He'd do just like random shitcorley probably thinks the same.
Speaker 3 (16:47):
Yeah, yeah, yeah, yeah he's like you, gotta be
prepared honestly, one thing Ialways like used to tell myself
is I want to be able to do apush-up with something heavy on
my back in case I get stucksomewhere, or like pull myself
out of a situation, like if Ican do that, I can get out of
(17:08):
anything but, if you're puttingin dire enough situation you you
can probably pull yourself outyeah, right, so I just stopped
putting myself in thosesituations.
Speaker 2 (17:17):
You just put your mind into it yeah make it happen
right, okay, so I have numbers,I have numbers on bird flu not
explosive diarrhea since
Speaker 1 (17:28):
2003 954 confirmed cases.
Half of those people have died52.
That's kind of crazy.
Yeah, that's a that's a lot.
Speaker 2 (17:37):
That's a high fatality rate.
Speaker 1 (17:38):
That's much more than easy corona but that's how many
people?
Speaker 3 (17:41):
thought they had it same thing with corona when it
originally came out.
They thought it was a higherpercentage, but they're
underestimating the total amountof people who had it Is the
bird flu from China.
Speaker 1 (17:50):
Yeah, that's true, because the sick people aren't
going in.
Yeah, I mean, it's basicallylike actually, it's like highest
number of bird flu deaths arein Indonesia, egypt, vietnam,
cambodia and China.
Speaker 3 (18:04):
The bat flu, the bat flu, okay All right, I'm done
looking at it, so I can eat raweggs.
Yeah, did we get an answer?
Speaker 2 (18:12):
Yeah, especially if you're starting to take
tereseptide.
I would definitely eat more raweggs.
Speaker 3 (18:16):
If there's, like, only 95 people who've ever
gotten bird flu.
Speaker 1 (18:21):
And those are the people that are, it looks like.
Speaker 3 (18:24):
They're inhaling chicken shit.
Speaker 1 (18:26):
Yeah, like that's just not probably the trick like
yeah, I I I doubt it's fromrange.
Speaker 4 (18:34):
Can you imagine if?
Speaker 2 (18:35):
because if one of those that qualify if someone's
tough to find those free-rangedorganic eggs someone gets
contaminated with the bird flu,from whatever farm.
Speaker 1 (18:44):
That is that person's life's over, so I'm pretty sure
they're trying to prevent thatfrom happening.
I would hope.
Speaker 3 (18:50):
So how many people have died of measles?
Speaker 2 (18:53):
Maybe we should look into buying an egg farm, you
know, because these guys, ifthey're dying off, measles is a
good one, but then we could getthe bird flu.
Yeah.
Speaker 3 (19:03):
That's called risky business.
You know what was hilariouswhen egg prices went fucking
crazy and bird flu was at itspeak.
I think it might be at its peaknow.
Supposedly it's been going onfor years.
Sprouts stopped carrying eggsand their egg cooler their egg
fridge.
They emptied it all out and itwas all filled with liquid death
(19:27):
.
The irony of that, I was likewhat I was like I thought this
is where I get the eggs.
And then I'm like I spent anextra 10 minutes because I'm
like Sarah's going to be pissedoff if I go home with no eggs.
There's got to be eggssomewhere over here.
Just start rummaging throughall the sprouts.
Speaker 2 (19:47):
So what are your thoughts on liquid?
It's sparkling water.
Speaker 3 (19:51):
It's not sparkling water, no, it's regular, it's
regular mineralized water.
Speaker 1 (19:54):
It can be regular.
It can be sparkling, it can bedifferent.
Tea, it is.
It's a bread.
Speaker 5 (19:58):
I actually like the taste.
Speaker 2 (20:01):
It's like a crisp water.
It's actually pretty good yeah,which was weird.
Speaker 1 (20:06):
Yeah, it's not bad.
I'm like I go and yeah, theyhave good iced teas.
Speaker 2 (20:16):
I don't drink anything with sugar in it.
Speaker 1 (20:18):
It's not really.
It's like agave.
Speaker 3 (20:22):
Yeah, like agave is worse than sugar, agave is
pretty much yeah.
See, that's why, I'm on theshow.
It spikes your sugars.
It's not influenza.
You're going to need to be onterzeptide.
It spikes your sugars.
Speaker 1 (20:36):
Have you guys had blue eggs though?
Yeah, what?
Yeah, blue eggs, blue eggs,they're supposedly like the most
raw, the free range.
Speaker 2 (20:44):
It's those the Vital Farms makes the blue eggs.
Speaker 3 (20:47):
Is it lower rates of bird flu?
Speaker 1 (20:48):
I think so.
Speaker 3 (20:49):
I got to switch.
Speaker 2 (20:56):
They look better Apparently there's less.
Speaker 3 (20:57):
Oh no, rfk.
They give them methylene blue.
No more food dye.
Speaker 1 (20:59):
It's not food dye, I'm kidding I guess the eggs are
the ones that are actuallysomething happens, whereas the
blue ones they don't.
But with the food dye, but Idon't even know exactly what it
is, but Saran's been crushingblue eggs lately.
Speaker 3 (21:12):
Where do you get blue eggs from?
Vital Farms been crushing blueeggs lately.
Speaker 2 (21:17):
So where do you get blue eggs from vital farms?
Vital, no, vital farms has thatsame free range, the brown and
black packages.
That same company makes blueeggs.
They're blue eggs.
Is the egg whites blue?
No, no whites are egg whitesare blue and the outside the
outsides the egg whites blue theegg whites a, isn't it, or is?
Speaker 1 (21:34):
it just the outside?
No, I don't think so.
I think it's just the outside,it's just the outside, yeah, I
don't know what's special aboutit.
Speaker 3 (21:41):
Is that what they fed the kids?
Speaker 1 (21:44):
in the boys TV show.
I haven't watched that show,but I'm assuming someone turned
blue.
Speaker 3 (21:49):
No, they did, it's the.
Speaker 2 (21:50):
Smurf chickens, smurf juice, all right on to our next
video Certain chicken eggsproduced that went completely
off topic.
Speaker 3 (21:58):
Yeah, yeah, that would yep.
Speaker 1 (22:02):
Thanks, Dr.
Speaker 3 (22:03):
Mike, back on topic.
Speaker 1 (22:09):
Oh, the color of an eggshell does not affect its
nutritional value or taste,that's what AI says, but that's
all I know.
Speaker 6 (22:14):
But the taste of that vital farms eggs are good, yeah
, better than any other ones,really, just see you can just
see the color of the eggs.
Speaker 3 (22:21):
I don't know if you could tell from what we've
talked about, but I'm like anegg aficionado.
Speaker 2 (22:27):
Let me judge this way dude my kid, my kids won't eat
any other eggs.
They're like, like, as soon asyou feed them other eggs,
they're like.
You know, I've always lovedrunny eggs.
Speaker 3 (22:37):
I don't know if you remember you were young, but mom
used to make the soft-boiledeggs.
You just crack the top and eatit.
Speaker 2 (22:43):
You can make real good ones sous vide.
I actually did them sous vide,they come pretty good.
Speaker 1 (22:48):
Yeah, that is probably good.
Speaker 2 (22:51):
But what's gotten kind of crazy lately is the
whole FDA and getting rid of thedrug shortage.
Speaker 3 (23:02):
Welcome to Age Proof, where we're going to talk about
random shit.
Make sure you live forever, allright, what's that?
Fda?
Speaker 2 (23:07):
So the whole FDA taking terzapetide and
semaglutide off the shortagelist, we've gotten quite a few
patients.
Speaker 3 (23:17):
What does that mean exactly to people?
Because people call in ourclinic.
Speaker 2 (23:21):
Yeah, asking for 50 vials of semaglutide.
Can I get like 80 vials ofsemaglutide?
And 100 vials of semaglutide,I'll get the Mexican stuff off
you too, if you have any of that.
So what it is is so Eli Lillyand Nova Nordisk hold patents to
the commercial drugs known asOzempic or Manjaro so and they
(23:45):
hold the patents till like 2032.
I don't know the exact date,but it's going to be a while.
But you know, so many peoplehave started taking them and
they couldn't keep up with theamount of need and one of the
main things was they couldn'tcreate enough needles to inject
with their pens the twodifferent companies.
(24:07):
Most of their patents behind thepen, not even the medication
Like I was just reading thatlike they do hold patents to the
medications themselves, becauseI had heard someone say that
it's patent to the pens, but no,it's it wouldn't make sense
yeah so.
So they couldn't come up withenough pens.
But now they can come up withenough pens, so they the fda is
(24:30):
pulling the drugs off theshortage list, which means the
compound pharmacies can't makethe medications if it's off the
shortage list.
So everyone's supposed to paythis exuberant amount of money
to buy these drugs from thecompanies themselves.
So now the companies havestarted to sell it direct, but
(24:51):
still it's much more expensivethan buying the compounded form.
Speaker 3 (24:56):
It's half the price of what it used to be but it's
four times the price of what youcan get.
Speaker 2 (25:03):
Yeah four times more than what you can get compounded
.
So there are ways around it andcertain certain pharmacies
still compound it becausethere's different things you can
add to decrease the sideeffects.
So they add some vitamin B6 todecrease the nausea.
You can add some glycine tosemaglutide to prevent muscle
(25:26):
loss.
And then the other thing peopleare doing is a lot of people do
microdosing.
No one wants to because thosepens, those pens, once you
inject it's done and you can'ttake different dosing and some
people don't require that entiredose.
Speaker 3 (25:42):
So micro oh yeah, because it's filled with a
certain amount, and that's it.
Speaker 2 (25:45):
You use it and yeah, whatever, you take that time and
that's it, yeah so if, ifyou're, you know, wanting to
lose 10 pounds or 15 pounds andyou only need, like you know,
for someide it's 0.25 milligrams, it's the lowest dose, you
could take 12.5 milligrams withthe compounded formula, where
with the pen you've got to takethe 0.25.
(26:07):
So, and especially once you getto, you know maintenance doses
and stuff and you want to takemore, you know, and kind of
titrate however you want.
You can't do that with the pensyou.
You can do that with acompounded formula, but you got
to be at least 10 percentdifferent than what the dose is
coming to be able to order fromthe compound pharmacy, but you
(26:28):
could still get it from thecompany and yeah, and there's
multiple ways around it which Idon't know if we're supposed to
say that you can go to.
Speaker 4 (26:36):
Mexico.
You could take half the doseand just do it twice.
Speaker 2 (26:47):
Do it twice a week instead of once a week if you're
getting the hunger pains.
But I don't know how this isgoing to turn out with, like
lawyers and stuff and there's somany people on it and, uh, you
know, big farmers just trying tocome out on top and you know
they are regulatory capture yeah, and they're also trying to say
, like how, these other drugcompounded forms have more side
(27:12):
effects, which isn't true.
Speaker 3 (27:14):
Um, or meanwhile.
Meanwhile, they get most ofthese drugs manufactured
overseas.
Speaker 2 (27:19):
It's all yeah china, turkey, um, you name it.
Like my friend went overseas totry different compounded
pharmacies from differentcountries and see where he could
find some.
Speaker 1 (27:35):
Did he know, yeah, what happened from that that you
got from your friend?
Speaker 2 (27:40):
I haven't used anything from there.
Speaker 1 (27:42):
He went missing.
Speaker 4 (27:46):
But what it's going to turn out to be.
He got the bird flu.
Speaker 1 (27:50):
What's going to turn out is going to be a lot more
black market stuff, oh yeah.
Speaker 3 (27:55):
People find it right yeah.
Speaker 2 (27:58):
And the thing is like we actually have access to the
newest one that's coming out,red True Tide, which is supposed
to be more effective.
In 48-week studies there wasmore weight loss about 25% as
compared to terazepatides, whichwas 22% 23%, and semaglutides
(28:19):
at 15%.
Speaker 3 (28:20):
What's the name of that new one, retatrutide, and
that has glucagon on top of GLPand GIP.
Speaker 2 (28:27):
Yeah, yeah.
So what I've read is like youknow your actual GLP-1 is your
semaglutide.
Your terzeptide is actually aGIP agonist that has an amino
acid different that makes italso act on the GLP-1 receptor.
(28:51):
It's not as strong of a GLP-1receptor agonist as your
semaglutide is, but it has tworeceptors.
Speaker 1 (29:01):
What happens when they're agonist to these
receptors?
What does it do exactly?
Speaker 2 (29:07):
It decreases or decreases satiety.
Speaker 6 (29:13):
Increases satiety.
Speaker 2 (29:14):
Yeah, Slow gastric emptying.
You're just hungry and you loseweight.
Speaker 3 (29:21):
It tells your brain you're full faster.
Speaker 2 (29:24):
Yeah, all the functions of a GLP-1.
Speaker 3 (29:26):
It tells you you're full faster.
Slows your gastric emptying.
It gives off the same.
Speaker 2 (29:31):
Increases insulin secretion.
Increases insulin sensitivity.
Speaker 1 (29:35):
Does it have an effect on the kidney?
Speaker 2 (29:38):
Yeah, it's got you know.
All the receptors areeverywhere in your body so it
affects all different parts ofyour body.
Speaker 3 (29:46):
Okay, but overall it seems beneficial.
Yeah, yeah, yeah, yeah, yeah,even for kidney chronic kidney
disease.
They're studying it for chronickidney disease Heart disease
kidney disease.
Speaker 4 (29:57):
Alzheimer's.
Speaker 2 (29:58):
Arthritis, alcohol withdrawal, fatty liver disease.
Speaker 3 (30:03):
Skinny liver disease.
Speaker 1 (30:07):
So would you recommend getting like for a
normal patient?
You would recommend getting itfrom a compounding pharmacy.
Speaker 3 (30:14):
What do you mean?
Normal patient?
I guess you can't say normal.
A little bit above weight, Ishouldn't say normal patient.
Speaker 4 (30:19):
No diabetes.
Speaker 1 (30:21):
Yeah, no diabetes, obviously.
Yeah, I mean, that's going tobe your typical like medical
patient is going to be diabetes,but person off the street who's
looking to just lose a littlebit of weight and they're a
little bit heavier and trying tocontrol you know what they're
eating get themselves in shape.
Speaker 2 (30:40):
So so you got to figure out why they're
overweight first.
You know it's checking thehormones and everything and
making sure everything's incheck before just trying like a
GLP one, you know and becausethe GLP might work or might not
work.
Speaker 3 (30:56):
And then if it doesn't work, then you got to
start all over again and be like, oh, why is this not working?
Yeah, I gotcha.
Speaker 2 (31:03):
Yeah, because sometimes it's like you got to
make sure the patient's sleepingenough.
Like some people can't loseweight with GLP-1s and they're
under high stress, they neversleep and they're wondering why
they can't lose weight.
There's like everything comestogether, like you gotta fix
your gut, you gotta, you know,eating whole foods.
Speaker 3 (31:24):
It's better to go step by step yeah, get there
rather than like trying to look.
It's an overall well-being.
It's not a miracle drug thatyou just take by itself.
Speaker 1 (31:33):
I mean it's a great drug.
Yeah, it's a fantastic drug.
Speaker 3 (31:36):
Yeah, but like if you just jump into it, like where a
lot of people do it too, theyjust prescribe it and it's like
okay, there you go and there'syour standard dose.
Take that until you're at yourweight and this is why I see,
like, how many percent of peopletry and get off of it.
It's like about a quarter, atleast 25% of people that just
(32:00):
like quit and never try it again.
It's not like they're like,okay, I try it, it's just like,
eh, yeah, I try to make me feelsick and rather than being like,
okay, did you test everythingelse out?
Or did you go to like the GLPipagonist, like, did you try a
different route?
Make sure?
Like, is your gut healthappropriate?
(32:21):
Like there's a lot of thingsthat can throw it off.
Speaker 2 (32:24):
So yeah, and then and then, on top of that, you also
you know you look for what thepatient needs with what you can
offer them to lose weight.
There's, there's a lot ofpeptides that you can offer them
to lose weight.
There's, there's a lot ofpeptides that you can offer um
to lose weight, whether it'slike a growth hormone uh
receptor agonist or, you know,there's testofenicine, which is
(32:44):
a different medication.
That um is almost like uhreoptic inhibitor of serotonin
dopaminerenaline so this is likessri.
Speaker 3 (32:56):
Almost it was a medication that they actually
created for alzheimer's yeah umbut when the glps originally
created for alzheimer's no no,the glps were diabetes.
Speaker 2 (33:11):
So the test fennel scene was created for
alzheimer's.
But the alzheimer's patients inthe study that were taking it
were losing all this weight andthey they're like you know.
So they stopped the study andthey dropped the drug because,
um, you don't want alzheimer'spatient losing all these this
weight and becoming sarcopenic Iknow that.
Speaker 3 (33:32):
I mean, that would be a weird situation.
Like doc, I lost all thisweight.
Oh really, how much did youweigh?
Speaker 1 (33:38):
I don't know yeah uh, so you guys feel like patients
that you've been prescribing itto like.
You feel like most people youtalk to have realistic
expectations.
Speaker 3 (33:57):
Obviously you set those as the physician right the
nice part with being inplastics is like.
You're already like it'sprobably the same way you
approach any patient.
You're like it's.
Are you realistic?
Can we get there?
Yeah, yeah like if somebody'slike I want to lose 120 pounds
maybe not, but if they're 340pounds and you go over the steps
(34:20):
that it'll take and theyreverberate and you get their
motivation and you're like itmight take this amount of time.
So it's patient by patient.
Yeah and they some people, it'sjust not going to happen they
you know they're going to liketake it like twice and then stop
and then blame you for it.
Like it's like, if you can, youcan't 100% nail it, but like, if
(34:43):
you can tell with like a goodchance of certainty, that like
they're going to be adherent towhat you tell them and they're
going to trust you, like youbuild that bond and when that
trust is built, like you knowthey're going to get the results
they want or at least get themto a reasonable place and and
you know, like our success ratesmuch higher than a lot of other
(35:05):
places because we're not justhanding it out, we know the side
effects.
Speaker 2 (35:08):
Yeah, um, also on my own trial and error, I figure
things out where I can helppatients with it, where, you
know, some people are like theydon't really know what the max
dose is, or like how to titratepatients up appropriately to get
them to their weight loss, ordiscuss nutrition and weight.
You know exercise and stuff withthem um, where, or like you
(35:33):
know this, this isn't working.
This might be a better thing totry to see if you lose, to see
if it works.
Or like adding on otherpeptides to help them, like, or
even hormone replacement and uh,or thyroid replacement to try
to get them to that level, oreven, you know, like vitamin d
(35:54):
replacement.
There's all these differentthings that you need in your
body to kind of be able to losethat weight.
And like sleep's a big thing,like people that don't sleep,
your cortisol level is going tobe increased.
You're going to have a toughtime, uh, losing that weight
feeling that today, yeah, notbecause of stress so it doesn't
(36:21):
work.
Speaker 5 (36:22):
When you get off of it, I gain double the weight
back after.
Speaker 4 (36:25):
If you stop taking ozempic or any of the other
glp-1 agonist medications, willyou gain double the weight back?
If only we had research to tellus this answer.
Thankfully we do.
But before we get to that, Ijust want to say that I cannot
tell you about her individualexperiences.
If she says that she gaineddouble the weight back after she
stopped taking Ozempic, thenI'm going to believe her, but
(36:46):
it's important to know if thatdid happen to her.
Just because it happened to herdoes not mean that's the norm
for everyone else who stopstaking it.
So, since we cannot extrapolateone individual person's
experience to a large population, what do we do?
We look at research, and theresearch that we have right now
come from the STEP trial.
So there was a STEP1 trialwhich showed that people lost a
significant amount of weightwith semaglutide.
(37:08):
This is something that I thinkpretty much everyone knows now.
The GLP-1 medications areincredible medications that help
with weight loss, but the bigquestion that arises is well, if
I stop that medication, am Igoing to gain the weight back?
Am I going to gain all theweight back, double the weight
back?
And so what they did is theytook the step one trial and
extended it, and they allowedpeople to stop taking the
medication to see what happened.
So when we look at the step oneextension trial, what we see is
(37:30):
that when people stop themedication, they do regain
weight, but it's not double theweight back and it's not really
all the way back either.
In this study, it showed thaton average, they gain about two
thirds of the weight back, whichis a significant amount.
But it's also important to knownot only did they just stop
semaglutide, they also stoppedtheir intensive lifestyle
regimen that they had been puton as well.
So what does this mean?
It means that obesity is achronic medical condition that's
(37:52):
going to need ongoing lifestylemodifications and, potentially,
medications to help keep theweight off, and that is okay.
No one should feel any stigmabehind needing to use medication
for weight loss or to keepweight off.
We are not all playing on thesame playing field.
We all have a differentbiological makeup and for some
of us, medications may be needed, and that is completely okay.
(38:15):
Lastly, you may be asking well,what if I want to stop the
medication?
I've lost the weight that Iwant to, but I just want to see
if I could stop it.
What I genuinely tell people istry it, to go a period of time
off of the medication and see ifyou can maintain your weight
off of it.
And if you can, that'sincredible, but if you can't,
there's's also no.
There should be no stigma andthere's no reason not to go back
(38:35):
on it.
At the end of the day, it'syour decision and what you
believe is best for your health.
So if you want to trial off ofit, just talk to your physician
about it and give it a shot, ordon't give it a shot anyway.
To end with, if you strugglewith obesity, do not let people
tell you you shouldn't be on amedication for weight loss.
It's just willpower.
That's not true.
Studies show that it's not true.
Do not feel bad for usingmedication to help you maintain
(38:55):
weight loss I.
Speaker 3 (38:57):
I agree with this guy , other than the fact that he's
chronically wearing astethoscope in the car.
Speaker 2 (39:02):
Yeah, I don't know why that's needed if the tesla
is burning, you got to go andtest the heartbeat right.
Speaker 3 (39:18):
No, he's right, he brings the data right Like you
expect about, like.
He's totally right, and that'sexactly what I tell my patients.
Speaker 2 (39:26):
I'm like, yeah, you're going to lose the weight
If you, if you don't keep upwith the lifestyle, you're not
going to and you got to titrateback down just like you titrated
up.
You can't just bounce on it,bounce off it, bounce on it.
You're going to regain theweight Like you're going to eat.
If you're going to eat likecrap and haven't changed your
lifestyle, you're going to gainthat weight back.
(39:48):
But yeah, it's not the sameamount of weight.
And, just like he said, obesityis a disease, just like high
blood pressure.
If you come off your high bloodpressure medications, your
blood pressure is going to betwice as high as it was before.
And you might stroke out and notlive At least with this you
gain some weight, so get back onthe drug and lose the weight.
Speaker 3 (40:11):
Try it out.
Yeah, go ahead, try it out.
I completely agree with that.
Speaker 1 (40:15):
Speaking about burning teslas, though I I was
with.
I was with my father-in-law.
How many do?
Speaker 3 (40:20):
you know where?
Speaker 1 (40:20):
no, we're, we're in the back of a tesla and the
bumper sticker says this is mylast tesla.
I'm just like you're legitdriving a tesla and you're like,
I mean I and you guys know yourpeople.
Speaker 3 (40:35):
Yeah, I lean democratic, obviously, but yeah,
and you guys know, that I toldyou guys we saw like the car in
front of us in front at ari'sschool dropping her off as a
tesla model 3 with a no elonsticker on it like yeah please
don't scratch my car, don't keymy car.
I Don't key my car.
I wonder.
The messed up part is they havethe most advanced camera
(40:58):
systems on them and theyautomatically go off and they
automatically record whensomeone gets close to it.
Yet people are like let me go.
Speaker 6 (41:07):
Let me go.
Speaker 3 (41:09):
I'm like a sneaky cat over here.
I wonder if he's got a bumpersticker.
Speaker 1 (41:13):
This is his last, so we want to destroy it like a
sneaky cat over here.
I wonder if the adjuster onPam's Tesla was.
Speaker 2 (41:18):
He was a Democrat because he crammed into him he
totaled it.
He put it as a total.
Speaker 3 (41:23):
But he was in a Jeep, though Jeep's a conservative
I'm saying like the adjuster theinsurance adjuster is like oh,
that car's totaled.
Speaker 1 (41:30):
Go burn it.
We'll give you double the priceyou burnt it.
I wish what we were talkingabout.
We'll give you double the priceyou burnt it.
You burnt it.
Speaker 3 (41:38):
I wish there were two Teslas next to each other.
Speaker 2 (41:40):
Well, I got Tesla stock, so the more Teslas they
burn, the more money they make,because they get all this
insurance money.
Speaker 3 (41:47):
I know they got to build more and sell more.
Thanks a lot.
It works for me.
A lot of production.
Speaker 1 (41:53):
What were we talking about?
Elon's plan ozempic?
Speaker 3 (41:56):
let's go back he just had a video, was elon on
ozempic, did he claim it, doeshe?
He must go on and off of it no,I think he looks like he's lost
weight because I remember therewas some beef with.
Mark Zuckerberg Like he waschallenging him to an MMA fight.
(42:18):
Oh yeah, because Elon's picturewent viral and he was all
overweight and pale.
Speaker 2 (42:25):
I don't know, Like Jeff Bezos, they showed those
pictures.
Dude, if you want to show me amiracle drug, show me something.
Speaker 3 (42:33):
you rub on Jeff Bezos' head that makes his hair
grow.
Now you want a miracle drug.
Give me that Like.
I'll prescribe that to anybody.
Speaker 1 (42:41):
Elon Musk dubs himself as Ozempic Santa yeah.
Speaker 4 (42:48):
I love it, I love it.
Speaker 2 (42:49):
I love it.
This is great.
Speaker 3 (42:54):
I mean he's a high-functioning person.
You can't.
There it is.
I mean you can't.
I don't know about you guys.
I recently lost like about 15pounds and it's like I'm
significantly out of breath.
When I was 15 pounds more doingnormal everyday stuff.
(43:15):
If I'm trying to be a highfunctional human being, like
it's like I'm picking somethingup and sarah's like why are you
breathing heavy?
I'm like I leaned over why elsewould I be breathing.
Speaker 2 (43:26):
It's like dude.
It gets difficult and it wasthat's.
That's the way I felt before Istarted this whole journey.
It's like yeah, I didn't wantto sit on the couch and I was
like you know, the wife wouldask for something.
I was like I'm going to punchher in the face.
Speaker 5 (43:45):
Why can't?
Speaker 2 (43:45):
you just get off the couch, but like now, I'm like
all right.
Speaker 3 (43:50):
I'll go.
Speaker 2 (43:51):
I'll go like three miles and grab it and come back.
Speaker 3 (43:54):
Now he's all pissed off.
Speaker 1 (43:55):
He's like I got to stop doing these jumping jacks
to go grab you these chips,speaking, of which I just got a
text, because I put away thegroceries and it was bite-sized
pancakes and I thought theybelonged in the cupboard, but
apparently they belonged in thefridge.
So those are gone.
Yes, in very kind words.
Speaker 2 (44:17):
Were they the Elmo ones?
Speaker 1 (44:19):
No no.
Speaker 2 (44:20):
No.
Speaker 1 (44:21):
They were for my pregnant wife.
I think more so than actuallythey were for my kids.
Speaker 2 (44:24):
She could still eat them.
Tell her they're tastier yeah.
They're ready to eat now, Imean, whatever they thought out,
just tell her, it's like readyto eat now and so you don't have
to even microwave.
Tell her, it's the saferversion.
Speaker 3 (44:36):
As long as you eat it before the fungus grows?
Yeah, and the fungus might begood, quick and easy tell me
they need to be refrigerated ohyeah, product refrigerated and
consumed within three days aftergo off his wife
Speaker 2 (44:48):
belgian boys, his wife's about to pop, so yeah.
Speaker 3 (44:54):
You can't be wasting pancake bites.
Not at month eight.
You're playing with fuckingfire, dude yeah.
Speaker 1 (45:03):
She might deliver right now.
Speaker 3 (45:05):
She's like nine and a half months pregnant.
Speaker 1 (45:07):
Yeah, yeah, I might need to leave the show.
Speaker 3 (45:10):
Is that Jim from the office?
Oh no, it's Dr Mike.
Speaker 6 (45:13):
Oh Zempik let's stay on that.
Speaker 3 (45:15):
To lose five pounds.
How do you feel about that?
Speaker 5 (45:17):
It's not what it's intended uses.
Why that's dangerous is becausewhen a medicine is studied by
this evil farmer that we'retalking about, it's studied in a
certain population people whohave type 2 diabetes, who are
overweight or have high bloodpressure.
So when you're taking it assomeone who doesn't have any of
these diagnoses and you take it,how do I know that the risks
you're facing are gonna be what?
The ones that we found in theresearch when we didn't test it
(45:39):
on people like you?
It's the same reason why wesuck at treating women's heart
disease, because we never didresearch on women's heart
disease.
So when a female patient comesin and says, oh, I have a little
acid reflux, maybe a little armpain, we discount it and
they're having a heart attack,because our initial research was
not done on women, it was doneon men who said I have an
elephant sitting on my chest.
This is how I describe it andthat's how our common knowledge
(46:00):
is of heart disease andtherefore we miss all these
heart attacks in women he's gotsome type of point, but if a
side effect's gonna show, it'sgonna show on a sick fucking
person, like if someone's goingto die from COVID is cause they
were really sick to start with.
Speaker 3 (46:15):
Like if you're telling me, this side effect
didn't show up on somebody thathas heart disease, history of
strokes, diabetes, but it'sgoing to show up.
Speaker 2 (46:24):
Yeah.
Speaker 3 (46:26):
But going to show up more on a healthy person.
I don't buy that shit for asecond I don't know.
Speaker 2 (46:35):
Well, unhealthy person.
I don't buy that shit for asecond, I don't know well and
you know a lot of these, a lotof medications.
You need to study everything onevery type of person.
But like no, and all thesemedications, any medications
that you look at like oh yeah,all of a sudden, some person's
gonna have a reaction, a weirdreaction that's never been seen
before, you know, like even mybrother-in-law.
He ended up in the hospital onlike some oh yeah fucking like
(46:56):
he was on a antibiotic that'slike pretty common and he almost
went into fulminant hepatitis.
Speaker 4 (47:04):
Um he was yeah, he was in the hospital for a few
days and we have, like ourparents, friend who, like they
gave her frickin didn't followthe liver labs.
Speaker 2 (47:16):
Well, no, they gave her what they gave her TB
medication because shepreviously had BCG vaccine and
she tested positive on the TBresults, and they gave her
frickin.
Tb medication and she went intoliver failure.
They had to.
Her daughter was her liverdonor.
(47:37):
If she wasn't around then shemight have died.
Speaker 1 (47:41):
That's how she went into liver failure.
It was from the meds, I said isit in rifampin.
Speaker 3 (47:46):
They didn't follow the liver labs appropriately.
Speaker 1 (47:48):
Are you kidding?
I didn't realize that's how shedecompensated.
At least, I didn't realizethat's how she decompensated.
Speaker 3 (47:53):
At least she didn't die of TB.
Yeah.
Speaker 2 (47:58):
If you don't trial and error these medications,
you're not going to Rapamycinnow.
It's an anti-aging medicationBefore it was used for
transplant patients Suppressthem.
Speaker 6 (48:11):
Yeah, like trial and error of some of these things.
Speaker 2 (48:14):
Are they going to have side effects?
And some patients, some people,yes, and they're all going to
have side effects.
And some people have genemutations that some medications
work on them and somemedications don't.
And actually one of my friendsis building an AI system which
actually like and he runs a genelab that like, tests all these
(48:35):
genes and like they can tellwhich medications actually work.
If, like, like some people,they you know, I hope it's not
23andMe they just want to bebankrupt.
It's 23andMe plus, but like what?
What his company's doing islike you know, if a patient gets
prescribed like Plavix and they, they have a gene mutation that
Plavix isn't going to work onthem.
(48:56):
What's going to happen is likethat AI is going to deny the guy
getting Plavix because Plavixisn't going to work as his
anti-platelet for whateverstents he has.
He needs to be on a differentmedication, so that that's going
to improve health care.
It's going to piss a lot ofphysicians off because it's
denying their care but they haveto like prior off for different
(49:20):
medications.
Speaker 1 (49:21):
that's actually going to work for the patient, yeah,
but I mean you got to imaginethat you could actually trial.
I'd be like, okay, see thismedication, this medication,
this medication and what isactually effective for this
person get this fly off of me,dude, he's been all around yeah,
he's all up in me reminds me ofthe breaking bad episode that
(49:43):
stopped me.
I was watching breaking badreligiously and then there was
an episode where they justchased a fly the whole time and
I was like I love this show, butI, I just wasted an hour, so
I'm done I and I stoppedwatching it I've watched it,
since it's gonna use a highschool chemistry teacher making
meth so you guys know somethingexciting.
Speaker 2 (50:04):
Hopefully the I finished the flat you know
something exciting.
Speaker 3 (50:07):
I just brought my, bought my own trailer.
Speaker 2 (50:09):
Yeah, I got jumpsuits .
Yeah, tomorrow I'm going to IVup and I'm going to try this
whole NAD and glutathione.
Speaker 3 (50:18):
Oh, yeah, yeah, oh, can't wait to hear about that.
Speaker 2 (50:35):
I'm going to record the whole thing and see, because
I just want to know how itfeels because a lot of people
say like it almost feels like anelephant on your chest, which
sounds like you're having aheart attack when you're getting
this IV NAD.
The good thing is I got themeta glasses, so I don't know.
Speaker 4 (50:46):
Maybe I should put the meta glasses on someone else
and see Dude you tried dying inour office before I know.
Try it again, don't do it.
Speaker 1 (50:51):
Third time's the charm, right?
So the second time is not.
We got to build this surgerycenter up.
Speaker 2 (50:56):
What else did?
Speaker 3 (50:56):
we have.
So we'll get you a wrap up onthe.
So it's NAD glutathione.
Speaker 1 (51:01):
Oh, that's going to be great.
Speaker 2 (51:02):
NAD, glutathione, b-complexes, some aminos.
Speaker 3 (51:07):
Dude, my sweet taste buds have not come back from
using the NAD nasal spray.
Oh yeah, Overdoing it.
It's actually like a good, likeside effect.
Speaker 2 (51:16):
Yeah.
Speaker 3 (51:17):
Because I'm like oh, that looks like a yummy cupcake.
Speaker 2 (51:20):
I'm going to see what happens.
I also started.
Speaker 1 (51:23):
No, just prescribe NAD spray Just order it, just
order it yeah.
I also started doing Just orderit online Like anyone, just
order it online like your doctororder it or compound pharmacy
prescribed.
Right, yeah, okay, no you couldorder it.
Speaker 3 (51:37):
You could order it online.
He doesn't know how toprescribe medication no, you no.
Speaker 1 (51:41):
You could order it online.
What do you order, though?
Is it just?
Speaker 2 (51:43):
you could just order it online, but you got to make
sure it's credible, because Idon't know.
Ours says it needs to berefrigerated, so some of these
places are just sending themlike you know, without being
refrigerated.
Speaker 4 (51:55):
So yeah, so those are probably more.
You can get it from thecompound pharmacies okay yeah,
taste buds.
Speaker 2 (52:02):
Now I also started doing IM injections of vitamin D
once a week what the fuck areyou not doing dude?
So yeah is the NAD.
He doesn't eat anymore.
Get my vitamin D.
What the fuck are you not doing?
Speaker 3 (52:12):
dude.
So, yeah, everything Is the NAD.
He doesn't eat anymore.
Is there any difference betweenthe NAD?
Speaker 1 (52:17):
sprays and, like IV or other, it's going to have
different effects of differentthings, you know it's like Some
people take pills.
Speaker 3 (52:26):
That stuff doesn't work.
Speaker 2 (52:29):
Well, it matters, but like nicotinamide, riboside is
probably the best form to takeorally.
A lot of people like over NMN.
Nmn, I guess, doesn't get intoyour cells as well.
So these are just precursors toNAD, so NAD, and so NMN and
nicotinamide riboside are yourprecursors for NAD and NAD
(52:53):
itself.
Even getting getting an iv itdoesn't get into your cells, um,
but you know people are seeingdrastic changes with energy and
you know mitochondrial functionand stuff.
Speaker 3 (53:03):
so anecdotal is anecdotal, yeah, yeah no, it's,
it's like.
Speaker 2 (53:09):
I've gone to so many different lectures about it and
it's like you know it's like,and even like in your
nicotinamide riboside or NMN.
Speaker 3 (53:21):
Like how much of it are you getting it?
Do you think that's why zinsare hot right now?
Speaker 6 (53:25):
Zins, zin.
Speaker 3 (53:27):
What's in?
Speaker 2 (53:28):
those, those packets.
Speaker 6 (53:29):
Isn't that nicotine?
Speaker 3 (53:32):
Is there nicotine broken down into nicotinamide?
Speaker 2 (53:36):
I don't think so.
I don't know how I was going tocheck on that.
Speaker 3 (53:38):
See the function of I was too like a year ago and I
decided not to I thought.
Speaker 1 (53:43):
I thought nicotine's just hitting your nicotinic
receptor.
Speaker 2 (53:46):
But I, I, you know I, but it kind of sounds the same,
but like I I was, I wasthinking the nasal, the nad
nasal spray like affects yourbrain more because it's through
the nasal passage and yeah, itgoes straight through your
cribriform plate.
Speaker 1 (54:01):
I thought so too that's why you get more energy.
That would make more sense.
Speaker 3 (54:04):
I honestly felt it with the nasal spray.
I was just like, okay, I don'tneed any caffeine today, like I
seriously I think I'm justhigher function, like when I
operate.
Speaker 2 (54:13):
I think I'm operating at a different level with nad
nasal spray the thing is, I dothat.
Speaker 3 (54:27):
I don't know if it's that or the ketone yeah, give me
another nasal spray.
Let's go.
Speaker 2 (54:36):
Six more flaps.
Speaker 1 (54:37):
Let's do it.
Let's do it.
I didn't know.
In the pre-op you got to askyour surgeon did you take your
NAD today?
Speaker 3 (54:46):
My patient asked me how are you feeling?
I'm like.
I feel great If I felt likeshit, I would not tell you.
I'm like yeah, I feel great.
If I felt like shit, I wouldnot tell you I'm just, I'm just
shaking like an appropriate wayto lead you into the or yeah
yeah yeah it's just like you'reserious.
I was like yeah, I was likehonestly, though it's monday, so
chances are I got pretty goodrest over the weekend or you got
(55:09):
really drunk over the weekend.
Speaker 2 (55:10):
That is true.
Speaker 3 (55:11):
Which I don't really do.
Well, rested baby let's go.
How are you feeling?
Oh, it's Friday.
I'm just doing this case to getthe week done.
Speaker 1 (55:24):
Can you imagine they're like how are you feeling
?
Oh yeah, whatever.
Speaker 3 (55:27):
I got a basketball game to go to tonight.
Let's go back.
Let's roll back.
Speaker 1 (55:33):
Let's do the surgery.
Speaker 2 (55:35):
Yeah, whatever so my thoughts on GLP-1s.
I love them.
I'll probably be on them forthe rest of my life and I kind
of mix it up and a few peoplehave asked me like I do the
Riturotide low dose and I doTERS Epitide, like I do them
like four days apart, becauseTERS Epitide definitely
(55:57):
suppresses your appetite a lotmore than the.
Speaker 3 (55:59):
Riturotide.
Oh, so you're doing the two andyou're going like every four
days Just low dose, yeah, Okay.
Speaker 2 (56:05):
Yeah, because Riturotide, you actually build
muscle.
So I'm just mixing, all right II think, overall for you, for
your health and like people maytell you differently, but
overall for your health, likethere's nothing more important
than keeping your glucosebalance.
I gotta get on a continuousglucose monitor to see, like,
(56:25):
how my sugars shift with eatingdifferent things, because
everyone's body respondsdifferently and especially,
being on GLP, see how thatmoderates it.
But like I think being on these, like for your liver health,
for your brain health, yourcardiovascular health and even
your joint health, overall Ithink it's a great product.
(56:49):
Try to get your hands on asmuch as you can before they get
taken off the market.
Uh, but they, you know, I Idon't think they'll ever
completely go off the market.
There's going to beavailability, um, because it's
going to get more dangerous ifthey don't allow these compound
(57:09):
pharmacies to make them.
It's going to become more of anissue with all these black
marketplaces showing up and whoknows, some of them may have
fentanyl or whatever in them and, like cause some deaths,
especially people injectingrandom things.
Yeah, and they couldn't havebacterial infections because the
compound pharmacies are veryhighly regulated, everything's
(57:31):
third-party tested.
But the main thing like peopletalk about like purity tested.
You could be purity tested butlike to be in that sterile
format versus.
Speaker 5 (57:44):
Pure versus clean is different?
Speaker 2 (57:46):
Yeah, because the compound pharmacies get their
stuff from the same place assome of these black market
places.
But sterility is going to bethe big part.
Are they as sterile as thecompound pharmacies have them?
Speaker 3 (58:00):
Yeah, and all I got to add to that is I personally
don't think in its current formit's like the like miracle drug
that like you see things likeCNnbc talking about stocks and
affecting like how many potatochip bags of potato chips are
going to be sold this week, Idon't think it's going to have
(58:21):
quite that much effect overall,but it's definitely very useful
and it can benefit a ton ofpeople with a good side effect
profile.
It has side effects butrelative like risk to benefits,
it's definitely worthwhile for alot of people.
Speaker 2 (58:37):
I think the side effect mainly came out when you
know FDA still had themedications on the shortage list
to they were trying to scarepeople away from getting them.
Now that it's back off theshortage list they're going to
minimize it.
Speaker 3 (58:52):
Yeah, yeah, they small words on yeah, on the uh
advertisement, yeah it's allabout the censorship on what
they they want to the untilpharma ads are made illegal now
yeah so it's the next push so.
so latest, latest, uh viral trends going on?
Uh, I have no clue, but I'veheard about this ozempic.
But what do you guys thinkabout the ozempic?
But do people get ozempic eyes?
Speaker 2 (00:33):
uh, they, they can't do.
You lose some fat in the eyesactually there.
Speaker 1 (00:38):
There's stuff about people that can like right after
they start ozempic.
Especially as we age, peopleget like blurred vision right
after because the blood sugarsare moving around a lot but.
Speaker 2 (00:51):
But like, how about the lower eyelids?
Do do they get more saggy, ordo do they?
Do they get more deflated?
Speaker 3 (00:58):
so why do you ask about?
That is what's behind theeyelid.
What do most?
Speaker 2 (01:02):
people see yeah, yeah , we go and take fat out, right,
yeah, does that fat shrink ever?
Or is that fat that that'sprobably like one of the last
things to shrink, right?
Speaker 1 (01:11):
yeah, so the fat's gonna be there from previously
and probably after a zempic,because they lose a little uh,
probably the.
They lose weight and then theskin becomes more lax, so it
probably becomes bigger.
Yeah, probably bigger fat padsthere.
Speaker 2 (01:28):
Yeah.
Speaker 1 (01:30):
Then more people would probably look towards a
lower blepharoplasty, which istaking the excess skin from the
lower eyelids and removing thefat.
Speaker 2 (01:38):
Yeah, so ozempic butt , yeah, it's a real thing and
it's more than just ozempic butt.
Me and Rods have been doingmore and more eight, 10 hour
cases because people haveOzempic arms, Ozempic legs, uh,
Ozempic everything.
Speaker 1 (01:52):
There's.
Speaker 2 (01:52):
Ozempic body, yeah, ozempic body where they've lost
all this weight.
Now there's the excess skin andfor them to build the
confidence and get back into thenormal daily activities.
It's tough when you're havingto put on Spanx to go and lift
and you're not seeing theresults on the scale still.
You know you can't really keepon going up on Ozempic or any of
(02:15):
these GLP-1s because whatthat's going to do is you're
going to just continue on losingmuscle mass as well as, like
fat mass.
But overall going up in dosageisn't going to help you much.
You want to maintain the dosage, just eat more protein and keep
the um, keep the muscle andozempic, but not are you just
(02:37):
losing weight and the skinsagging, but you're also going
to lose some muscle mass.
So you know you got to continueon doing squats and your
resistance exercises with thatto kind of like if you're having
surgery to help these thingsout, you also want to kind of
continue on building that muscle, right, Whatever you say.
Speaker 3 (02:58):
Yeah, definitely Like , cause you'll, you'll drop.
You'll definitely drop musclemass if you don't do anything,
if you sit around.
But it's like they're saying oh, people are coming out with
ozempic butt, ozempic face.
That's kind of why you'retaking the medication right, you
actually want that.
So if you actually get ozempicbutt or ozempic face, that's
(03:19):
just telling you you have weightloss.
Those are your fat pockets.
And now those fat pockets aredeflating and once that's
deflating, the skin sags.
That's just classic signs ofaging.
Right, like during training,they're like these are classic
signs of your facial aging.
It's like it's plump.
Your, your face is like ovaland then like it gradually drops
(03:41):
down with age.
Same thing happens if you gainweight and then drop a bunch of
weight.
Speaker 2 (03:46):
It's going to sag and whether it's your face, your
butt, Just like when I had like23-inch arms and I thought I was
huge.
Then I lost all that weight andmy skin's like what's that
stretch arm strong?
Speaker 3 (03:57):
This can stretch out to 23 inches.
You know that much.
Speaker 2 (04:01):
Yeah, I take semaglutide, take I take
semaglutide.
I've taken semaglutide.
I take terzeptide.
I take red true tide.
Do I have ozempic?
But my wife would probably sayno, because I never had a butt
to get ozempic, but so you gotto really have a butt to
actually lose it, but you wearspanks to work uh, no, he wears
sometimes sometimes
Speaker 1 (04:26):
I wear more leg warmers.
Speaker 2 (04:27):
But it's kind of like , yeah, it keeps my butt up I
have heard.
Speaker 3 (04:32):
I have heard uh on different like podcasts, youtube
videos and stuff.
People are afraid to lose theirmuscle mass and uh, bone
density density as a side effectfrom taking Ozempic or GLP-1,
whether it's Manjaro OzempicWegovy.
But how can you prevent that ordiminish that?
Speaker 2 (04:59):
You really can't prevent it because, no matter
what, you're decreasing calorieintake, so that's going to
decrease it.
You're also decreasing theamount of weight and stress on
your bones, so that decrease,decrease weight is also going to
decrease the amount of musclesand stuff you need to carry that
extra 10, 20, 30 pounds.
Speaker 3 (05:19):
That you know what also does that if you get sent
out to the space station and youget stuck there for eight
months for political reasons.
You're going to lose bonedensity and muscle mass.
Speaker 2 (05:30):
But maybe everyone needs to wear a weighted jacket,
like a lot of these people dothese days just to simulate that
extra weight being on them sowhen they're walking around
daily.
Speaker 3 (05:41):
that actually benefits you in multiple ways
anyhow, but is the uh, like thethe bone density and skeletal
muscle mass lost relative tooverall weight proportional, or
are they losing more?
Like, let's say, more bone massand skeletal muscle mass
compared to overall mass?
Speaker 2 (06:01):
it's patient dependent.
You know I've been on it for, Ithink, almost three years and
you know, like that first sixmonths I probably lost a lot of
weight and I lost muscle mass.
But after that six months I'vegained muscle mass and kind of
kept at the same weight.
And, like you know, I microdoseand like change dosing, like
when I go on vacation and stufflike sometimes to get cut up and
(06:25):
sometimes you know, and youknow, just play around with a
dosing.
But I've always put on moreskeletal muscle mass over the
past two years.
That first six months was theonly time I think I lost a
little bit of the muscle massand the thing is like increasing
protein and I wasn't reallyworking out that first six
(06:45):
months but once the weight cameoff I started working out and I
think that kind of like.
Also, you know you can't live asedentary lifestyle.
I think you're going to, um,just lose, uh.
Speaker 3 (06:59):
Oh yeah, asking for like a chemical way to starve
yourself?
Yeah, that makes sense, I'mgoing to start it.
I've been saying it for like ayear I starve yourself.
Yeah, that makes sense, I'mgonna start it.
I've been saying it for like ayear I just want to see the
difference.
But I've you saw, I sent you thein-body results.
I'm actually able to get downmy body fat percentage yeah,
nowhere near what I wanted andincrease my skeletal muscle mass
.
I actually wanted to increasemy skeletal muscle mass to about
(07:23):
like two more pounds than whereit is right now.
It's already up like fourpounds, yeah, but then get on
some terzapatide yeah, so thensee how lean I can get.
Yeah, with like small doses,but not but like.
Speaker 2 (07:36):
Also, the other thing that people don't look at is
like optimizing your hormones,like, yeah, your your
testosterone um and also yourthyroid hormone, you know, like
just optimizing those.
You'll also need a lower doseof your glp-1s um to be able to
maintain your muscle mass andlose weight and have the energy
(07:58):
to go work out and be focusedand get on with daily activities
.
Instead of, like you know,people are like, oh, glp ones
are going to cause me to betired and I don't want to do
anything, but they're becauseyou're taking them the wrong way
.
If you're taking them withappropriate vitamin and
nutrition and like with abalance lifestyle changes that
(08:20):
you know that appropriatephysicians will lead you the
right way instead of you know,yeah, you could pay someone like
99 bucks a week or 99, howevermuch of your pain, and they're
just handing you the medicationand telling you unless you're
self-motivated, which usuallyaren't, that's why you're on
these medications, You're you'renot going gonna get to the
(08:43):
point you really want to andyou're never going to be able to
come off of them or be likemicro dosing just for health
purposes.
Yeah, because you're.
You're still living that samelifestyle that as soon as you
come off of them, you're goingto eat bad stuff and not work
out, and it you know.
Speaker 3 (09:01):
You it or you get off because you're craving that
stuff.
Speaker 2 (09:04):
You're like, ah, I want to eat some more cake now.
Yeah, so I'm going to this.
Speaker 3 (09:10):
This thing prevents me from wanting to eat more cake
.
Speaker 2 (09:12):
Yeah, I find like, as I lowered my dose, like I was
shopping more frequently online.
Whatever I wanted, I was buyingonline.
Speaker 3 (09:21):
Really, it's seriously when you lower your
dose.
When I lowered, yeah, there'sdefinitely some effect, because
I started.
Speaker 2 (09:28):
I started like doing it once every two, three weeks
and I felt like, yeah, I wasdefinitely.
I was like, all right, I needto up my dose a little bit.
Speaker 3 (09:35):
I'm buying too much.
So if your wife's buying toomuch, stuff online yeah, that's
a good, good indication to getsome.
Speaker 2 (09:44):
You can offer a nice massage and just rub it in.
Yeah, quick little shot.
It won't hurt nobody Do we wantto see the video and go from.
Speaker 3 (09:54):
Yeah, what video are we watching?
Speaker 2 (09:57):
Dr Mike was talking about Ozempic butt.
Speaker 6 (09:59):
I don't want to exercise, I'll just take Ozempic
.
That's the thing I'm sureyou're aware of, like Ozempic
butt or whatever, wherehousewives who had no interest
in resistance training orbuilding muscularity, no
interest in controlling theirdiets or eating healthier, they
just take a crapload of Ozempicand they're like oh, I've lost a
ton of weight, but now I'msarcopenic.
That's definitely a bad outcome, but I would say that's more of
(10:19):
a slight misapplication ofpharmaceutical technology, and
there is such a thing as properapplication and I think in the
end we'll have a cocktail ofdrugs that are increasingly
better at doing things,increasingly lower risks and
downsides.
I think that's a world we wantto live in.
Speaker 3 (10:36):
Which one's Dr Mike with glasses, one's a real
doctor, is he a?
Chiropractor?
No, he's a physical therapistor like exercise physiologist.
I listened to him on a podcast,yeah, and it sounds like he
knows what he's talking about.
It's like, oh yeah, best way togain strength is probably based
on some research.
I didn't even look it up.
It's like going to like max,like range.
Speaker 2 (11:01):
Yeah.
Speaker 3 (11:02):
And light reps Light reps make a lot of sense to me
and max range light reps make alot of sense to me and max range
like extending the musclefibers makes sense to me too.
But I swear that next day Iwent and did like deep squats
yeah, my back hurt like fuckinghell.
Like I was like ah, I knew Ishouldn't have fucking done that
.
Like I'm not building muscleCause my muscle, my fucking back
(11:24):
hurts.
Speaker 2 (11:24):
But.
But like the, the way to umwork out, like with the
resistance bands and theresistance bands, you're doing
high reps, it's not very highweight, and what you're doing is
you don't want to lock out atall, you want to go, you want to
keep the ranges in betweenwhere you're going up and down,
so your muscles are alwaysengaged.
Speaker 3 (11:44):
I might have misunderstood them, yeah, but it
was pretty much saying kind oflike what?
Corley tells us like yeah oh,you gotta range out with like
the squats go like, and it'sjust like you know what.
Maybe I don't need to do thatyeah, I don't um, I'm not trying
to get that strong no, um.
Speaker 2 (12:02):
Well, you know you gotta slowly, like what corley
was saying.
You gotta kind of slowly getthere because you know your
ankles kind of stiffen up quitea bit pretty quickly.
Speaker 3 (12:14):
So you gotta get them on here.
Speaker 2 (12:16):
That would actually be hilarious I know he listens
to a lot especially if you starttalking about black rights
activists and stuff.
Speaker 3 (12:24):
A whole mix of things Deep squats versus DI yeah.
Speaker 2 (12:29):
And why you need to do explosive exercises.
For a lot of you'll needexplosiveness in your life.
Speaker 3 (12:39):
As an anesthesiologist, I was going to
just ask.
Speaker 2 (12:45):
I've been going lower carbs.
Speaker 3 (12:49):
I've been eating raw eggs.
Do I need to worry aboutanything about the bird flu
going on?
Speaker 2 (12:55):
No, because they killed off a lot of eggs.
Speaker 1 (12:58):
Yeah, they shouldn't be.
It shouldn't reach me right?
No, I don't think so.
Speaker 3 (13:02):
Okay, because I don't want to take the time to cook
the eggs.
It's so much easier.
Speaker 2 (13:06):
But does it matter if you cook it or not?
With the bird flu, I don't know.
I don't think it matters.
That's why they took it off theshelf.
Speaker 3 (13:14):
They said most ways of contracting bird flu is
coming in contact with it.
Speaker 4 (13:25):
So at least like three to eight people have
gotten bird flu before I do.
Speaker 2 (13:28):
Do you need a Fauci vaccine if you get it?
So what happens if you get thebird flu?
You might die.
Speaker 3 (13:34):
Oh yeah, that's why I'm asking you.
Speaker 1 (13:41):
You guys are clearly the wrong.
Can you get bird flu throughLike?
Is it oral?
Speaker 3 (13:46):
Through contact.
I don't know they got rid ofall those eggs.
No but like could you eat birdflu Can?
Speaker 1 (13:51):
it be fecal-oral Not fecal-oral necessarily.
Speaker 3 (13:56):
Not everything has to be fecal-oral.
Speaker 1 (14:01):
I mean that's one of the routes I'm talking about
eggs.
Speaker 3 (14:04):
I'm not talking about shit.
I'm not talking about shit.
Speaker 6 (14:06):
I'm not eating shit, yeah, but.
Speaker 2 (14:08):
Well those chickens are shitting those eggs out.
Speaker 3 (14:11):
But I don't literally eat shit, I don't think.
No, it said contact with birds.
Speaker 2 (14:16):
So, it's usually the bird farmers that, get it, but
like what happens with the eggsthat they had to kill off all
those eggs?
Speaker 3 (14:25):
It's just the chickens passing the shit around
themselves, so okay.
Speaker 2 (14:30):
So killing off the eggs isn't going to pass the
Eating undercooked eggs oh yeah,is that?
Speaker 3 (14:35):
number one.
I'll hold off on that.
Speaker 1 (14:39):
Number one is contact with infected birds of course.
Speaker 2 (14:42):
What does it give you ?
Does it give you diarrhea?
Speaker 3 (14:45):
No, you can fucking die.
It's scary shit.
If it was just like a little,you know me and diarrhea I'm
cool with.
Like I'm not going to die ofdiarrhea.
I'm in the developed world.
Speaker 1 (15:00):
I'll give you guys a death rate for bird flu in a
second.
See what AI tells us.
I'll give you guys a death ratefor bird flu in a second.
See what AI tells us.
Wait, what was this?
Speaker 3 (15:09):
episode about oh shit .
Speaker 4 (15:14):
And while okay, so yeah, Close contact with
infected birds or contaminatedenvironments.
Speaker 1 (15:19):
While the risk of human-to-human transmission is
low, the mortality rate forknown human cases is around 50%.
Oh shit, you can die.
You can die.
One out of two die.
Speaker 2 (15:31):
It's like people that get it are probably like pretty
sick people.
Speaker 1 (15:35):
Yeah, they're knee-deep in birds.
Speaker 3 (15:36):
Yeah, we're talking about these farms with like
thousands and thousands ofchicken in them.
Speaker 2 (15:43):
Yeah, you probably get like freakingicking high
dose of bird flu.
Speaker 3 (15:47):
I'm just picturing Napoleon Dynamite tending to
chicken.
Speaker 1 (15:52):
Speaking about explosive exercises oh exercise.
I was like, oh, you got theright guy, I know exactly
everything about explosivediarrhea.
Speaker 2 (16:03):
Me too, me too.
But okay, let's think of thechat.
Well, eat at chamber.
Speaker 1 (16:08):
The last three months I've gotten the first two food
poisonings of my life.
Speaker 2 (16:12):
Dude you guys scared the crap out of me Like I won't
even eat fruit at that place.
Speaker 1 (16:17):
I know I look and I'm like, oh, that's a salad bar.
I don't know if I could.
I'm going to go grab the saladfrom the fridge I'm gonna
probably at least it's in thefridge.
And then he says, ah, nevermind, I'll take the meatloaf no,
my buddy and uh, my collegeroommate used to he always be
like, yeah, you gotta doexplosive exercises, he's like.
(16:40):
He's like you gotta be ready ifthe apocalypse happens, you
gotta be ready.
He'd do just like random shitcorley probably thinks the same.
Speaker 3 (16:47):
Yeah, yeah, yeah, yeah he's like you, gotta be
prepared honestly, one thing Ialways like used to tell myself
is I want to be able to do apush-up with something heavy on
my back in case I get stucksomewhere, or like pull myself
out of a situation, like if Ican do that, I can get out of
(17:08):
anything but, if you're puttingin dire enough situation you you
can probably pull yourself outyeah, right, so I just stopped
putting myself in thosesituations.
Speaker 2 (17:17):
You just put your mind into it yeah make it happen
right, okay, so I have numbers,I have numbers on bird flu not
explosive diarrhea since
Speaker 1 (17:28):
2003 954 confirmed cases.
Half of those people have died52.
That's kind of crazy.
Yeah, that's a that's a lot.
Speaker 2 (17:37):
That's a high fatality rate.
Speaker 1 (17:38):
That's much more than easy corona but that's how many
people?
Speaker 3 (17:41):
thought they had it same thing with corona when it
originally came out.
They thought it was a higherpercentage, but they're
underestimating the total amountof people who had it Is the
bird flu from China.
Speaker 1 (17:50):
Yeah, that's true, because the sick people aren't
going in.
Yeah, I mean, it's basicallylike actually, it's like highest
number of bird flu deaths arein Indonesia, egypt, vietnam,
cambodia and China.
Speaker 3 (18:04):
The bat flu, the bat flu, okay All right, I'm done
looking at it, so I can eat raweggs.
Yeah, did we get an answer?
Speaker 2 (18:12):
Yeah, especially if you're starting to take
tereseptide.
I would definitely eat more raweggs.
Speaker 3 (18:16):
If there's, like, only 95 people who've ever
gotten bird flu.
Speaker 1 (18:21):
And those are the people that are, it looks like.
Speaker 3 (18:24):
They're inhaling chicken shit.
Speaker 1 (18:26):
Yeah, like that's just not probably the trick like
yeah, I I I doubt it's fromrange.
Speaker 4 (18:34):
Can you imagine if?
Speaker 2 (18:35):
because if one of those that qualify if someone's
tough to find those free-rangedorganic eggs someone gets
contaminated with the bird flu,from whatever farm.
Speaker 1 (18:44):
That is that person's life's over, so I'm pretty sure
they're trying to prevent thatfrom happening.
I would hope.
Speaker 3 (18:50):
So how many people have died of measles?
Speaker 2 (18:53):
Maybe we should look into buying an egg farm, you
know, because these guys, ifthey're dying off, measles is a
good one, but then we could getthe bird flu.
Yeah.
Speaker 3 (19:03):
That's called risky business.
You know what was hilariouswhen egg prices went fucking
crazy and bird flu was at itspeak.
I think it might be at its peaknow.
Supposedly it's been going onfor years.
Sprouts stopped carrying eggsand their egg cooler their egg
fridge.
They emptied it all out and itwas all filled with liquid death
(19:27):
.
The irony of that, I was likewhat I was like I thought this
is where I get the eggs.
And then I'm like I spent anextra 10 minutes because I'm
like Sarah's going to be pissedoff if I go home with no eggs.
There's got to be eggssomewhere over here.
Just start rummaging throughall the sprouts.
Speaker 2 (19:47):
So what are your thoughts on liquid?
It's sparkling water.
Speaker 3 (19:51):
It's not sparkling water, no, it's regular, it's
regular mineralized water.
Speaker 1 (19:54):
It can be regular.
It can be sparkling, it can bedifferent.
Tea, it is.
It's a bread.
Speaker 5 (19:58):
I actually like the taste.
Speaker 2 (20:01):
It's like a crisp water.
It's actually pretty good yeah,which was weird.
Speaker 1 (20:06):
Yeah, it's not bad.
I'm like I go and yeah, theyhave good iced teas.
Speaker 2 (20:16):
I don't drink anything with sugar in it.
Speaker 1 (20:18):
It's not really.
It's like agave.
Speaker 3 (20:22):
Yeah, like agave is worse than sugar, agave is
pretty much yeah.
See, that's why, I'm on theshow.
It spikes your sugars.
It's not influenza.
You're going to need to be onterzeptide.
It spikes your sugars.
Speaker 1 (20:36):
Have you guys had blue eggs though?
Yeah, what?
Yeah, blue eggs, blue eggs,they're supposedly like the most
raw, the free range.
Speaker 2 (20:44):
It's those the Vital Farms makes the blue eggs.
Speaker 3 (20:47):
Is it lower rates of bird flu?
Speaker 1 (20:48):
I think so.
Speaker 3 (20:49):
I got to switch.
Speaker 2 (20:56):
They look better Apparently there's less.
Speaker 3 (20:57):
Oh no, rfk.
They give them methylene blue.
No more food dye.
Speaker 1 (20:59):
It's not food dye, I'm kidding I guess the eggs are
the ones that are actuallysomething happens, whereas the
blue ones they don't.
But with the food dye, but Idon't even know exactly what it
is, but Saran's been crushingblue eggs lately.
Speaker 3 (21:12):
Where do you get blue eggs from?
Vital Farms been crushing blueeggs lately.
Speaker 2 (21:17):
So where do you get blue eggs from vital farms?
Vital, no, vital farms has thatsame free range, the brown and
black packages.
That same company makes blueeggs.
They're blue eggs.
Is the egg whites blue?
No, no whites are egg whitesare blue and the outside the
outsides the egg whites blue theegg whites a, isn't it, or is?
Speaker 1 (21:34):
it just the outside?
No, I don't think so.
I think it's just the outside,it's just the outside, yeah, I
don't know what's special aboutit.
Speaker 3 (21:41):
Is that what they fed the kids?
Speaker 1 (21:44):
in the boys TV show.
I haven't watched that show,but I'm assuming someone turned
blue.
Speaker 3 (21:49):
No, they did, it's the.
Speaker 2 (21:50):
Smurf chickens, smurf juice, all right on to our next
video Certain chicken eggsproduced that went completely
off topic.
Speaker 3 (21:58):
Yeah, yeah, that would yep.
Speaker 1 (22:02):
Thanks, Dr.
Speaker 3 (22:03):
Mike, back on topic.
Speaker 1 (22:09):
Oh, the color of an eggshell does not affect its
nutritional value or taste,that's what AI says, but that's
all I know.
Speaker 6 (22:14):
But the taste of that vital farms eggs are good, yeah
, better than any other ones,really, just see you can just
see the color of the eggs.
Speaker 3 (22:21):
I don't know if you could tell from what we've
talked about, but I'm like anegg aficionado.
Speaker 2 (22:27):
Let me judge this way dude my kid, my kids won't eat
any other eggs.
They're like, like, as soon asyou feed them other eggs,
they're like.
You know, I've always lovedrunny eggs.
Speaker 3 (22:37):
I don't know if you remember you were young, but mom
used to make the soft-boiledeggs.
You just crack the top and eatit.
Speaker 2 (22:43):
You can make real good ones sous vide.
I actually did them sous vide,they come pretty good.
Speaker 1 (22:48):
Yeah, that is probably good.
Speaker 2 (22:51):
But what's gotten kind of crazy lately is the
whole FDA and getting rid of thedrug shortage.
Speaker 3 (23:02):
Welcome to Age Proof, where we're going to talk about
random shit.
Make sure you live forever, allright, what's that?
Fda?
Speaker 2 (23:07):
So the whole FDA taking terzapetide and
semaglutide off the shortagelist, we've gotten quite a few
patients.
Speaker 3 (23:17):
What does that mean exactly to people?
Because people call in ourclinic.
Speaker 2 (23:21):
Yeah, asking for 50 vials of semaglutide.
Can I get like 80 vials ofsemaglutide?
And 100 vials of semaglutide,I'll get the Mexican stuff off
you too, if you have any of that.
So what it is is so Eli Lillyand Nova Nordisk hold patents to
the commercial drugs known asOzempic or Manjaro so and they
(23:45):
hold the patents till like 2032.
I don't know the exact date,but it's going to be a while.
But you know, so many peoplehave started taking them and
they couldn't keep up with theamount of need and one of the
main things was they couldn'tcreate enough needles to inject
with their pens the twodifferent companies.
(24:07):
Most of their patents behind thepen, not even the medication
Like I was just reading thatlike they do hold patents to the
medications themselves, becauseI had heard someone say that
it's patent to the pens, but no,it's it wouldn't make sense
yeah so.
So they couldn't come up withenough pens.
But now they can come up withenough pens, so they the fda is
(24:30):
pulling the drugs off theshortage list, which means the
compound pharmacies can't makethe medications if it's off the
shortage list.
So everyone's supposed to paythis exuberant amount of money
to buy these drugs from thecompanies themselves.
So now the companies havestarted to sell it direct, but
(24:51):
still it's much more expensivethan buying the compounded form.
Speaker 3 (24:56):
It's half the price of what it used to be but it's
four times the price of what youcan get.
Speaker 2 (25:03):
Yeah four times more than what you can get compounded
.
So there are ways around it andcertain certain pharmacies
still compound it becausethere's different things you can
add to decrease the sideeffects.
So they add some vitamin B6 todecrease the nausea.
You can add some glycine tosemaglutide to prevent muscle
(25:26):
loss.
And then the other thing peopleare doing is a lot of people do
microdosing.
No one wants to because thosepens, those pens, once you
inject it's done and you can'ttake different dosing and some
people don't require that entiredose.
Speaker 3 (25:42):
So micro oh yeah, because it's filled with a
certain amount, and that's it.
Speaker 2 (25:45):
You use it and yeah, whatever, you take that time and
that's it, yeah so if, ifyou're, you know, wanting to
lose 10 pounds or 15 pounds andyou only need, like you know,
for someide it's 0.25 milligrams, it's the lowest dose, you
could take 12.5 milligrams withthe compounded formula, where
with the pen you've got to takethe 0.25.
(26:07):
So, and especially once you getto, you know maintenance doses
and stuff and you want to takemore, you know, and kind of
titrate however you want.
You can't do that with the pensyou.
You can do that with acompounded formula, but you got
to be at least 10 percentdifferent than what the dose is
coming to be able to order fromthe compound pharmacy, but you
(26:28):
could still get it from thecompany and yeah, and there's
multiple ways around it which Idon't know if we're supposed to
say that you can go to.
Speaker 4 (26:36):
Mexico.
You could take half the doseand just do it twice.
Speaker 2 (26:47):
Do it twice a week instead of once a week if you're
getting the hunger pains.
But I don't know how this isgoing to turn out with, like
lawyers and stuff and there's somany people on it and, uh, you
know, big farmers just trying tocome out on top and you know
they are regulatory capture yeah, and they're also trying to say
, like how, these other drugcompounded forms have more side
(27:12):
effects, which isn't true.
Speaker 3 (27:14):
Um, or meanwhile.
Meanwhile, they get most ofthese drugs manufactured
overseas.
Speaker 2 (27:19):
It's all yeah china, turkey, um, you name it.
Like my friend went overseas totry different compounded
pharmacies from differentcountries and see where he could
find some.
Speaker 1 (27:35):
Did he know, yeah, what happened from that that you
got from your friend?
Speaker 2 (27:40):
I haven't used anything from there.
Speaker 1 (27:42):
He went missing.
Speaker 4 (27:46):
But what it's going to turn out to be.
He got the bird flu.
Speaker 1 (27:50):
What's going to turn out is going to be a lot more
black market stuff, oh yeah.
Speaker 3 (27:55):
People find it right yeah.
Speaker 2 (27:58):
And the thing is like we actually have access to the
newest one that's coming out,red True Tide, which is supposed
to be more effective.
In 48-week studies there wasmore weight loss about 25% as
compared to terazepatides, whichwas 22% 23%, and semaglutides
(28:19):
at 15%.
Speaker 3 (28:20):
What's the name of that new one, retatrutide, and
that has glucagon on top of GLPand GIP.
Speaker 2 (28:27):
Yeah, yeah.
So what I've read is like youknow your actual GLP-1 is your
semaglutide.
Your terzeptide is actually aGIP agonist that has an amino
acid different that makes italso act on the GLP-1 receptor.
(28:51):
It's not as strong of a GLP-1receptor agonist as your
semaglutide is, but it has tworeceptors.
Speaker 1 (29:01):
What happens when they're agonist to these
receptors?
What does it do exactly?
Speaker 2 (29:07):
It decreases or decreases satiety.
Speaker 6 (29:13):
Increases satiety.
Speaker 2 (29:14):
Yeah, Slow gastric emptying.
You're just hungry and you loseweight.
Speaker 3 (29:21):
It tells your brain you're full faster.
Speaker 2 (29:24):
Yeah, all the functions of a GLP-1.
Speaker 3 (29:26):
It tells you you're full faster.
Slows your gastric emptying.
It gives off the same.
Speaker 2 (29:31):
Increases insulin secretion.
Increases insulin sensitivity.
Speaker 1 (29:35):
Does it have an effect on the kidney?
Speaker 2 (29:38):
Yeah, it's got you know.
All the receptors areeverywhere in your body so it
affects all different parts ofyour body.
Speaker 3 (29:46):
Okay, but overall it seems beneficial.
Yeah, yeah, yeah, yeah, yeah,even for kidney chronic kidney
disease.
They're studying it for chronickidney disease Heart disease
kidney disease.
Speaker 4 (29:57):
Alzheimer's.
Speaker 2 (29:58):
Arthritis, alcohol withdrawal, fatty liver disease.
Speaker 3 (30:03):
Skinny liver disease.
Speaker 1 (30:07):
So would you recommend getting like for a
normal patient?
You would recommend getting itfrom a compounding pharmacy.
Speaker 3 (30:14):
What do you mean?
Normal patient?
I guess you can't say normal.
A little bit above weight, Ishouldn't say normal patient.
Speaker 4 (30:19):
No diabetes.
Speaker 1 (30:21):
Yeah, no diabetes, obviously.
Yeah, I mean, that's going tobe your typical like medical
patient is going to be diabetes,but person off the street who's
looking to just lose a littlebit of weight and they're a
little bit heavier and trying tocontrol you know what they're
eating get themselves in shape.
Speaker 2 (30:40):
So so you got to figure out why they're
overweight first.
You know it's checking thehormones and everything and
making sure everything's incheck before just trying like a
GLP one, you know and becausethe GLP might work or might not
work.
Speaker 3 (30:56):
And then if it doesn't work, then you got to
start all over again and be like, oh, why is this not working?
Yeah, I gotcha.
Speaker 2 (31:03):
Yeah, because sometimes it's like you got to
make sure the patient's sleepingenough.
Like some people can't loseweight with GLP-1s and they're
under high stress, they neversleep and they're wondering why
they can't lose weight.
There's like everything comestogether, like you gotta fix
your gut, you gotta, you know,eating whole foods.
Speaker 3 (31:24):
It's better to go step by step yeah, get there
rather than like trying to look.
It's an overall well-being.
It's not a miracle drug thatyou just take by itself.
Speaker 1 (31:33):
I mean it's a great drug.
Yeah, it's a fantastic drug.
Speaker 3 (31:36):
Yeah, but like if you just jump into it, like where a
lot of people do it too, theyjust prescribe it and it's like
okay, there you go and there'syour standard dose.
Take that until you're at yourweight and this is why I see,
like, how many percent of peopletry and get off of it.
It's like about a quarter, atleast 25% of people that just
(32:00):
like quit and never try it again.
It's not like they're like,okay, I try it, it's just like,
eh, yeah, I try to make me feelsick and rather than being like,
okay, did you test everythingelse out?
Or did you go to like the GLPipagonist, like, did you try a
different route?
Make sure?
Like, is your gut healthappropriate?
(32:21):
Like there's a lot of thingsthat can throw it off.
Speaker 2 (32:24):
So yeah, and then and then, on top of that, you also
you know you look for what thepatient needs with what you can
offer them to lose weight.
There's, there's a lot ofpeptides that you can offer them
to lose weight.
There's, there's a lot ofpeptides that you can offer um
to lose weight, whether it'slike a growth hormone uh
receptor agonist or, you know,there's testofenicine, which is
(32:44):
a different medication.
That um is almost like uhreoptic inhibitor of serotonin
dopaminerenaline so this is likessri.
Speaker 3 (32:56):
Almost it was a medication that they actually
created for alzheimer's yeah umbut when the glps originally
created for alzheimer's no no,the glps were diabetes.
Speaker 2 (33:11):
So the test fennel scene was created for
alzheimer's.
But the alzheimer's patients inthe study that were taking it
were losing all this weight andthey they're like you know.
So they stopped the study andthey dropped the drug because,
um, you don't want alzheimer'spatient losing all these this
weight and becoming sarcopenic Iknow that.
Speaker 3 (33:32):
I mean, that would be a weird situation.
Like doc, I lost all thisweight.
Oh really, how much did youweigh?
Speaker 1 (33:38):
I don't know yeah uh, so you guys feel like patients
that you've been prescribing itto like.
You feel like most people youtalk to have realistic
expectations.
Speaker 3 (33:57):
Obviously you set those as the physician right the
nice part with being inplastics is like.
You're already like it'sprobably the same way you
approach any patient.
You're like it's.
Are you realistic?
Can we get there?
Yeah, yeah like if somebody'slike I want to lose 120 pounds
maybe not, but if they're 340pounds and you go over the steps
(34:20):
that it'll take and theyreverberate and you get their
motivation and you're like itmight take this amount of time.
So it's patient by patient.
Yeah and they some people, it'sjust not going to happen they
you know they're going to liketake it like twice and then stop
and then blame you for it.
Like it's like, if you can, youcan't 100% nail it, but like, if
(34:43):
you can tell with like a goodchance of certainty, that like
they're going to be adherent towhat you tell them and they're
going to trust you, like youbuild that bond and when that
trust is built, like you knowthey're going to get the results
they want or at least get themto a reasonable place and and
you know, like our success ratesmuch higher than a lot of other
(35:05):
places because we're not justhanding it out, we know the side
effects.
Speaker 2 (35:08):
Yeah, um, also on my own trial and error, I figure
things out where I can helppatients with it, where, you
know, some people are like theydon't really know what the max
dose is, or like how to titratepatients up appropriately to get
them to their weight loss, ordiscuss nutrition and weight.
You know exercise and stuff withthem um, where, or like you
(35:33):
know this, this isn't working.
This might be a better thing totry to see if you lose, to see
if it works.
Or like adding on otherpeptides to help them, like, or
even hormone replacement and uh,or thyroid replacement to try
to get them to that level, oreven, you know, like vitamin d
(35:54):
replacement.
There's all these differentthings that you need in your
body to kind of be able to losethat weight.
And like sleep's a big thing,like people that don't sleep,
your cortisol level is going tobe increased.
You're going to have a toughtime, uh, losing that weight
feeling that today, yeah, notbecause of stress so it doesn't
(36:21):
work.
Speaker 5 (36:22):
When you get off of it, I gain double the weight
back after.
Speaker 4 (36:25):
If you stop taking ozempic or any of the other
glp-1 agonist medications, willyou gain double the weight back?
If only we had research to tellus this answer.
Thankfully we do.
But before we get to that, Ijust want to say that I cannot
tell you about her individualexperiences.
If she says that she gaineddouble the weight back after she
stopped taking Ozempic, thenI'm going to believe her, but
(36:46):
it's important to know if thatdid happen to her.
Just because it happened to herdoes not mean that's the norm
for everyone else who stopstaking it.
So, since we cannot extrapolateone individual person's
experience to a large population, what do we do?
We look at research, and theresearch that we have right now
come from the STEP trial.
So there was a STEP1 trialwhich showed that people lost a
significant amount of weightwith semaglutide.
(37:08):
This is something that I thinkpretty much everyone knows now.
The GLP-1 medications areincredible medications that help
with weight loss, but the bigquestion that arises is well, if
I stop that medication, am Igoing to gain the weight back?
Am I going to gain all theweight back, double the weight
back?
And so what they did is theytook the step one trial and
extended it, and they allowedpeople to stop taking the
medication to see what happened.
So when we look at the step oneextension trial, what we see is
(37:30):
that when people stop themedication, they do regain
weight, but it's not double theweight back and it's not really
all the way back either.
In this study, it showed thaton average, they gain about two
thirds of the weight back, whichis a significant amount.
But it's also important to knownot only did they just stop
semaglutide, they also stoppedtheir intensive lifestyle
regimen that they had been puton as well.
So what does this mean?
It means that obesity is achronic medical condition that's
(37:52):
going to need ongoing lifestylemodifications and, potentially,
medications to help keep theweight off, and that is okay.
No one should feel any stigmabehind needing to use medication
for weight loss or to keepweight off.
We are not all playing on thesame playing field.
We all have a differentbiological makeup and for some
of us, medications may be needed, and that is completely okay.
(38:15):
Lastly, you may be asking well,what if I want to stop the
medication?
I've lost the weight that Iwant to, but I just want to see
if I could stop it.
What I genuinely tell people istry it, to go a period of time
off of the medication and see ifyou can maintain your weight
off of it.
And if you can, that'sincredible, but if you can't,
there's's also no.
There should be no stigma andthere's no reason not to go back
(38:35):
on it.
At the end of the day, it'syour decision and what you
believe is best for your health.
So if you want to trial off ofit, just talk to your physician
about it and give it a shot, ordon't give it a shot anyway.
To end with, if you strugglewith obesity, do not let people
tell you you shouldn't be on amedication for weight loss.
It's just willpower.
That's not true.
Studies show that it's not true.
Do not feel bad for usingmedication to help you maintain
(38:55):
weight loss I.
Speaker 3 (38:57):
I agree with this guy , other than the fact that he's
chronically wearing astethoscope in the car.
Speaker 2 (39:02):
Yeah, I don't know why that's needed if the tesla
is burning, you got to go andtest the heartbeat right.
Speaker 3 (39:18):
No, he's right, he brings the data right Like you
expect about, like.
He's totally right, and that'sexactly what I tell my patients.
Speaker 2 (39:26):
I'm like, yeah, you're going to lose the weight
If you, if you don't keep upwith the lifestyle, you're not
going to and you got to titrateback down just like you titrated
up.
You can't just bounce on it,bounce off it, bounce on it.
You're going to regain theweight Like you're going to eat.
If you're going to eat likecrap and haven't changed your
lifestyle, you're going to gainthat weight back.
(39:48):
But yeah, it's not the sameamount of weight.
And, just like he said, obesityis a disease, just like high
blood pressure.
If you come off your high bloodpressure medications, your
blood pressure is going to betwice as high as it was before.
And you might stroke out and notlive At least with this you
gain some weight, so get back onthe drug and lose the weight.
Speaker 3 (40:11):
Try it out.
Yeah, go ahead, try it out.
I completely agree with that.
Speaker 1 (40:15):
Speaking about burning teslas, though I I was
with.
I was with my father-in-law.
How many do?
Speaker 3 (40:20):
you know where?
Speaker 1 (40:20):
no, we're, we're in the back of a tesla and the
bumper sticker says this is mylast tesla.
I'm just like you're legitdriving a tesla and you're like,
I mean I and you guys know yourpeople.
Speaker 3 (40:35):
Yeah, I lean democratic, obviously, but yeah,
and you guys know, that I toldyou guys we saw like the car in
front of us in front at ari'sschool dropping her off as a
tesla model 3 with a no elonsticker on it like yeah please
don't scratch my car, don't keymy car.
I Don't key my car.
I wonder.
The messed up part is they havethe most advanced camera
(40:58):
systems on them and theyautomatically go off and they
automatically record whensomeone gets close to it.
Yet people are like let me go.
Speaker 6 (41:07):
Let me go.
Speaker 3 (41:09):
I'm like a sneaky cat over here.
I wonder if he's got a bumpersticker.
Speaker 1 (41:13):
This is his last, so we want to destroy it like a
sneaky cat over here.
I wonder if the adjuster onPam's Tesla was.
Speaker 2 (41:18):
He was a Democrat because he crammed into him he
totaled it.
He put it as a total.
Speaker 3 (41:23):
But he was in a Jeep, though Jeep's a conservative
I'm saying like the adjuster theinsurance adjuster is like oh,
that car's totaled.
Speaker 1 (41:30):
Go burn it.
We'll give you double the priceyou burnt it.
I wish what we were talkingabout.
We'll give you double the priceyou burnt it.
You burnt it.
Speaker 3 (41:38):
I wish there were two Teslas next to each other.
Speaker 2 (41:40):
Well, I got Tesla stock, so the more Teslas they
burn, the more money they make,because they get all this
insurance money.
Speaker 3 (41:47):
I know they got to build more and sell more.
Thanks a lot.
It works for me.
A lot of production.
Speaker 1 (41:53):
What were we talking about?
Elon's plan ozempic?
Speaker 3 (41:56):
let's go back he just had a video, was elon on
ozempic, did he claim it, doeshe?
He must go on and off of it no,I think he looks like he's lost
weight because I remember therewas some beef with.
Mark Zuckerberg Like he waschallenging him to an MMA fight.
(42:18):
Oh yeah, because Elon's picturewent viral and he was all
overweight and pale.
Speaker 2 (42:25):
I don't know, Like Jeff Bezos, they showed those
pictures.
Dude, if you want to show me amiracle drug, show me something.
Speaker 3 (42:33):
you rub on Jeff Bezos' head that makes his hair
grow.
Now you want a miracle drug.
Give me that Like.
I'll prescribe that to anybody.
Speaker 1 (42:41):
Elon Musk dubs himself as Ozempic Santa yeah.
Speaker 4 (42:48):
I love it, I love it.
Speaker 2 (42:49):
I love it.
This is great.
Speaker 3 (42:54):
I mean he's a high-functioning person.
You can't.
There it is.
I mean you can't.
I don't know about you guys.
I recently lost like about 15pounds and it's like I'm
significantly out of breath.
When I was 15 pounds more doingnormal everyday stuff.
(43:15):
If I'm trying to be a highfunctional human being, like
it's like I'm picking somethingup and sarah's like why are you
breathing heavy?
I'm like I leaned over why elsewould I be breathing.
Speaker 2 (43:26):
It's like dude.
It gets difficult and it wasthat's.
That's the way I felt before Istarted this whole journey.
It's like yeah, I didn't wantto sit on the couch and I was
like you know, the wife wouldask for something.
I was like I'm going to punchher in the face.
Speaker 5 (43:45):
Why can't?
Speaker 2 (43:45):
you just get off the couch, but like now, I'm like
all right.
Speaker 3 (43:50):
I'll go.
Speaker 2 (43:51):
I'll go like three miles and grab it and come back.
Speaker 3 (43:54):
Now he's all pissed off.
Speaker 1 (43:55):
He's like I got to stop doing these jumping jacks
to go grab you these chips,speaking, of which I just got a
text, because I put away thegroceries and it was bite-sized
pancakes and I thought theybelonged in the cupboard, but
apparently they belonged in thefridge.
So those are gone.
Yes, in very kind words.
Speaker 2 (44:17):
Were they the Elmo ones?
Speaker 1 (44:19):
No no.
Speaker 2 (44:20):
No.
Speaker 1 (44:21):
They were for my pregnant wife.
I think more so than actuallythey were for my kids.
Speaker 2 (44:24):
She could still eat them.
Tell her they're tastier yeah.
They're ready to eat now, Imean, whatever they thought out,
just tell her, it's like readyto eat now and so you don't have
to even microwave.
Tell her, it's the saferversion.
Speaker 3 (44:36):
As long as you eat it before the fungus grows?
Yeah, and the fungus might begood, quick and easy tell me
they need to be refrigerated ohyeah, product refrigerated and
consumed within three days aftergo off his wife
Speaker 2 (44:48):
belgian boys, his wife's about to pop, so yeah.
Speaker 3 (44:54):
You can't be wasting pancake bites.
Not at month eight.
You're playing with fuckingfire, dude yeah.
Speaker 1 (45:03):
She might deliver right now.
Speaker 3 (45:05):
She's like nine and a half months pregnant.
Speaker 1 (45:07):
Yeah, yeah, I might need to leave the show.
Speaker 3 (45:10):
Is that Jim from the office?
Oh no, it's Dr Mike.
Speaker 6 (45:13):
Oh Zempik let's stay on that.
Speaker 3 (45:15):
To lose five pounds.
How do you feel about that?
Speaker 5 (45:17):
It's not what it's intended uses.
Why that's dangerous is becausewhen a medicine is studied by
this evil farmer that we'retalking about, it's studied in a
certain population people whohave type 2 diabetes, who are
overweight or have high bloodpressure.
So when you're taking it assomeone who doesn't have any of
these diagnoses and you take it,how do I know that the risks
you're facing are gonna be what?
The ones that we found in theresearch when we didn't test it
(45:39):
on people like you?
It's the same reason why wesuck at treating women's heart
disease, because we never didresearch on women's heart
disease.
So when a female patient comesin and says, oh, I have a little
acid reflux, maybe a little armpain, we discount it and
they're having a heart attack,because our initial research was
not done on women, it was doneon men who said I have an
elephant sitting on my chest.
This is how I describe it andthat's how our common knowledge
(46:00):
is of heart disease andtherefore we miss all these
heart attacks in women he's gotsome type of point, but if a
side effect's gonna show, it'sgonna show on a sick fucking
person, like if someone's goingto die from COVID is cause they
were really sick to start with.
Speaker 3 (46:15):
Like if you're telling me, this side effect
didn't show up on somebody thathas heart disease, history of
strokes, diabetes, but it'sgoing to show up.
Speaker 2 (46:24):
Yeah.
Speaker 3 (46:26):
But going to show up more on a healthy person.
I don't buy that shit for asecond I don't know.
Speaker 2 (46:35):
Well, unhealthy person.
I don't buy that shit for asecond, I don't know well and
you know a lot of these, a lotof medications.
You need to study everything onevery type of person.
But like no, and all thesemedications, any medications
that you look at like oh yeah,all of a sudden, some person's
gonna have a reaction, a weirdreaction that's never been seen
before, you know, like even mybrother-in-law.
He ended up in the hospital onlike some oh yeah fucking like
(46:56):
he was on a antibiotic that'slike pretty common and he almost
went into fulminant hepatitis.
Speaker 4 (47:04):
Um he was yeah, he was in the hospital for a few
days and we have, like ourparents, friend who, like they
gave her frickin didn't followthe liver labs.
Speaker 2 (47:16):
Well, no, they gave her what they gave her TB
medication because shepreviously had BCG vaccine and
she tested positive on the TBresults, and they gave her
frickin.
Tb medication and she went intoliver failure.
They had to.
Her daughter was her liverdonor.
(47:37):
If she wasn't around then shemight have died.
Speaker 1 (47:41):
That's how she went into liver failure.
It was from the meds, I said isit in rifampin.
Speaker 3 (47:46):
They didn't follow the liver labs appropriately.
Speaker 1 (47:48):
Are you kidding?
I didn't realize that's how shedecompensated.
At least, I didn't realizethat's how she decompensated.
Speaker 3 (47:53):
At least she didn't die of TB.
Yeah.
Speaker 2 (47:58):
If you don't trial and error these medications,
you're not going to Rapamycinnow.
It's an anti-aging medicationBefore it was used for
transplant patients Suppressthem.
Speaker 6 (48:11):
Yeah, like trial and error of some of these things.
Speaker 2 (48:14):
Are they going to have side effects?
And some patients, some people,yes, and they're all going to
have side effects.
And some people have genemutations that some medications
work on them and somemedications don't.
And actually one of my friendsis building an AI system which
actually like and he runs a genelab that like, tests all these
(48:35):
genes and like they can tellwhich medications actually work.
If, like, like some people,they you know, I hope it's not
23andMe they just want to bebankrupt.
It's 23andMe plus, but like what?
What his company's doing islike you know, if a patient gets
prescribed like Plavix and they, they have a gene mutation that
Plavix isn't going to work onthem.
(48:56):
What's going to happen is likethat AI is going to deny the guy
getting Plavix because Plavixisn't going to work as his
anti-platelet for whateverstents he has.
He needs to be on a differentmedication, so that that's going
to improve health care.
It's going to piss a lot ofphysicians off because it's
denying their care but they haveto like prior off for different
(49:20):
medications.
Speaker 1 (49:21):
that's actually going to work for the patient, yeah,
but I mean you got to imaginethat you could actually trial.
I'd be like, okay, see thismedication, this medication,
this medication and what isactually effective for this
person get this fly off of me,dude, he's been all around yeah,
he's all up in me reminds me ofthe breaking bad episode that
(49:43):
stopped me.
I was watching breaking badreligiously and then there was
an episode where they justchased a fly the whole time and
I was like I love this show, butI, I just wasted an hour, so
I'm done I and I stoppedwatching it I've watched it,
since it's gonna use a highschool chemistry teacher making
meth so you guys know somethingexciting.
Speaker 2 (50:04):
Hopefully the I finished the flat you know
something exciting.
Speaker 3 (50:07):
I just brought my, bought my own trailer.
Speaker 2 (50:09):
Yeah, I got jumpsuits .
Yeah, tomorrow I'm going to IVup and I'm going to try this
whole NAD and glutathione.
Speaker 3 (50:18):
Oh, yeah, yeah, oh, can't wait to hear about that.
Speaker 2 (50:35):
I'm going to record the whole thing and see, because
I just want to know how itfeels because a lot of people
say like it almost feels like anelephant on your chest, which
sounds like you're having aheart attack when you're getting
this IV NAD.
The good thing is I got themeta glasses, so I don't know.
Speaker 4 (50:46):
Maybe I should put the meta glasses on someone else
and see Dude you tried dying inour office before I know.
Try it again, don't do it.
Speaker 1 (50:51):
Third time's the charm, right?
So the second time is not.
We got to build this surgerycenter up.
Speaker 2 (50:56):
What else did?
Speaker 3 (50:56):
we have.
So we'll get you a wrap up onthe.
So it's NAD glutathione.
Speaker 1 (51:01):
Oh, that's going to be great.
Speaker 2 (51:02):
NAD, glutathione, b-complexes, some aminos.
Speaker 3 (51:07):
Dude, my sweet taste buds have not come back from
using the NAD nasal spray.
Oh yeah, Overdoing it.
It's actually like a good, likeside effect.
Speaker 2 (51:16):
Yeah.
Speaker 3 (51:17):
Because I'm like oh, that looks like a yummy cupcake.
Speaker 2 (51:20):
I'm going to see what happens.
I also started.
Speaker 1 (51:23):
No, just prescribe NAD spray Just order it, just
order it yeah.
I also started doing Just orderit online Like anyone, just
order it online like your doctororder it or compound pharmacy
prescribed.
Right, yeah, okay, no you couldorder it.
Speaker 3 (51:37):
You could order it online.
He doesn't know how toprescribe medication no, you no.
Speaker 1 (51:41):
You could order it online.
What do you order, though?
Is it just?
Speaker 2 (51:43):
you could just order it online, but you got to make
sure it's credible, because Idon't know.
Ours says it needs to berefrigerated, so some of these
places are just sending themlike you know, without being
refrigerated.
Speaker 4 (51:55):
So yeah, so those are probably more.
You can get it from thecompound pharmacies okay yeah,
taste buds.
Speaker 2 (52:02):
Now I also started doing IM injections of vitamin D
once a week what the fuck areyou not doing dude?
So yeah is the NAD.
He doesn't eat anymore.
Get my vitamin D.
What the fuck are you not doing?
Speaker 3 (52:12):
dude.
So, yeah, everything Is the NAD.
He doesn't eat anymore.
Is there any difference betweenthe NAD?
Speaker 1 (52:17):
sprays and, like IV or other, it's going to have
different effects of differentthings, you know it's like Some
people take pills.
Speaker 3 (52:26):
That stuff doesn't work.
Speaker 2 (52:29):
Well, it matters, but like nicotinamide, riboside is
probably the best form to takeorally.
A lot of people like over NMN.
Nmn, I guess, doesn't get intoyour cells as well.
So these are just precursors toNAD, so NAD, and so NMN and
nicotinamide riboside are yourprecursors for NAD and NAD
(52:53):
itself.
Even getting getting an iv itdoesn't get into your cells, um,
but you know people are seeingdrastic changes with energy and
you know mitochondrial functionand stuff.
Speaker 3 (53:03):
so anecdotal is anecdotal, yeah, yeah no, it's,
it's like.
Speaker 2 (53:09):
I've gone to so many different lectures about it and
it's like you know it's like,and even like in your
nicotinamide riboside or NMN.
Speaker 3 (53:21):
Like how much of it are you getting it?
Do you think that's why zinsare hot right now?
Speaker 6 (53:25):
Zins, zin.
Speaker 3 (53:27):
What's in?
Speaker 2 (53:28):
those, those packets.
Speaker 6 (53:29):
Isn't that nicotine?
Speaker 3 (53:32):
Is there nicotine broken down into nicotinamide?
Speaker 2 (53:36):
I don't think so.
I don't know how I was going tocheck on that.
Speaker 3 (53:38):
See the function of I was too like a year ago and I
decided not to I thought.
Speaker 1 (53:43):
I thought nicotine's just hitting your nicotinic
receptor.
Speaker 2 (53:46):
But I, I, you know I, but it kind of sounds the same,
but like I I was, I wasthinking the nasal, the nad
nasal spray like affects yourbrain more because it's through
the nasal passage and yeah, itgoes straight through your
cribriform plate.
Speaker 1 (54:01):
I thought so too that's why you get more energy.
That would make more sense.
Speaker 3 (54:04):
I honestly felt it with the nasal spray.
I was just like, okay, I don'tneed any caffeine today, like I
seriously I think I'm justhigher function, like when I
operate.
Speaker 2 (54:13):
I think I'm operating at a different level with nad
nasal spray the thing is, I dothat.
Speaker 3 (54:27):
I don't know if it's that or the ketone yeah, give me
another nasal spray.
Let's go.
Speaker 2 (54:36):
Six more flaps.
Speaker 1 (54:37):
Let's do it.
Let's do it.
I didn't know.
In the pre-op you got to askyour surgeon did you take your
NAD today?
Speaker 3 (54:46):
My patient asked me how are you feeling?
I'm like.
I feel great If I felt likeshit, I would not tell you.
I'm like yeah, I feel great.
If I felt like shit, I wouldnot tell you I'm just, I'm just
shaking like an appropriate wayto lead you into the or yeah
yeah yeah it's just like you'reserious.
I was like yeah, I was likehonestly, though it's monday, so
chances are I got pretty goodrest over the weekend or you got
(55:09):
really drunk over the weekend.
Speaker 2 (55:10):
That is true.
Speaker 3 (55:11):
Which I don't really do.
Well, rested baby let's go.
How are you feeling?
Oh, it's Friday.
I'm just doing this case to getthe week done.
Speaker 1 (55:24):
Can you imagine they're like how are you feeling
?
Oh yeah, whatever.
Speaker 3 (55:27):
I got a basketball game to go to tonight.
Let's go back.
Let's roll back.
Speaker 1 (55:33):
Let's do the surgery.
Speaker 2 (55:35):
Yeah, whatever so my thoughts on GLP-1s.
I love them.
I'll probably be on them forthe rest of my life and I kind
of mix it up and a few peoplehave asked me like I do the
Riturotide low dose and I doTERS Epitide, like I do them
like four days apart, becauseTERS Epitide definitely
(55:57):
suppresses your appetite a lotmore than the.
Speaker 3 (55:59):
Riturotide.
Oh, so you're doing the two andyou're going like every four
days Just low dose, yeah, Okay.
Speaker 2 (56:05):
Yeah, because Riturotide, you actually build
muscle.
So I'm just mixing, all right II think, overall for you, for
your health and like people maytell you differently, but
overall for your health, likethere's nothing more important
than keeping your glucosebalance.
I gotta get on a continuousglucose monitor to see, like,
(56:25):
how my sugars shift with eatingdifferent things, because
everyone's body respondsdifferently and especially,
being on GLP, see how thatmoderates it.
But like I think being on these, like for your liver health,
for your brain health, yourcardiovascular health and even
your joint health, overall Ithink it's a great product.
(56:49):
Try to get your hands on asmuch as you can before they get
taken off the market.
Uh, but they, you know, I Idon't think they'll ever
completely go off the market.
There's going to beavailability, um, because it's
going to get more dangerous ifthey don't allow these compound
(57:09):
pharmacies to make them.
It's going to become more of anissue with all these black
marketplaces showing up and whoknows, some of them may have
fentanyl or whatever in them and, like cause some deaths,
especially people injectingrandom things.
Yeah, and they couldn't havebacterial infections because the
compound pharmacies are veryhighly regulated, everything's
(57:31):
third-party tested.
But the main thing like peopletalk about like purity tested.
You could be purity tested butlike to be in that sterile
format versus.
Speaker 5 (57:44):
Pure versus clean is different?
Speaker 2 (57:46):
Yeah, because the compound pharmacies get their
stuff from the same place assome of these black market
places.
But sterility is going to bethe big part.
Are they as sterile as thecompound pharmacies have them?
Speaker 3 (58:00):
Yeah, and all I got to add to that is I personally
don't think in its current formit's like the like miracle drug
that like you see things likeCNnbc talking about stocks and
affecting like how many potatochip bags of potato chips are
going to be sold this week, Idon't think it's going to have
(58:21):
quite that much effect overall,but it's definitely very useful
and it can benefit a ton ofpeople with a good side effect
profile.
It has side effects butrelative like risk to benefits,
it's definitely worthwhile for alot of people.
Speaker 2 (58:37):
I think the side effect mainly came out when you
know FDA still had themedications on the shortage list
to they were trying to scarepeople away from getting them.
Now that it's back off theshortage list they're going to
minimize it.
Speaker 3 (58:52):
Yeah, yeah, they small words on yeah, on the uh
advertisement, yeah it's allabout the censorship on what
they they want to the untilpharma ads are made illegal now
yeah so it's the next push so.
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