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May 11, 2025 47 mins

Dr. Satterlee is an Assistant Professor at the University of North Carolina at Chapel Hill and the Director of the Screening Live Cancer Explants Program and Core Facility at Eshelman Innovation — an academic institute focused on translating groundbreaking ideas into real solutions for patients.

Since beginning his PhD in 2011 as a National Science Foundation Graduate Research Fellow, Dr. Satterlee has spent over 14 years developing new cancer therapies and better, more predictive models to test those therapies. Through this work, he’s seen firsthand the limitations of traditional cancer models — from the artificiality of in vitro assays, to the high cost of animal studies, and the overwhelming lack of standardization across the field.

This work is deeply personal for him. At 20 years old, he was diagnosed with a rare, heterogeneous brain tumor. With no clear consensus among his doctors, it was ultimately up to him — the patient — to choose between standard-of-care whole brain radiation or a newer chemotherapy option with promising early data. It was in that moment that he knew: there had to be a better way to help providers and patients make informed treatment decisions. And today, he’s building that tool.

In 2016, Dr. Satterlee began developing a unique drug screening platform alongside an interdisciplinary team of scientists and clinicians, including pediatric neuro-oncologist Dr. David Kram. Their system allows for real-time testing of patient tumor tissue — taken straight from the operating room to the lab. It’s already being used to help identify more effective therapies, minimize reliance on animal models, guide clinical trial enrollment, and inform real-time treatment decisions for patients with brain tumors, as well as other cancers like ovarian and lung.

find out more @ https://slice.unc.edu/

You can also get involved with the Gold Ribbon Kids Cancer Foundation or the National Pediatric Cancer Foundation through fundraising, volunteering, promoting awareness, or contributing to pediatric cancer research. Visit goldribbon-kids.org or nationalpcf.org for more information

To contact Tiffany, please email info@goldribbon-kids.org
To contact Kelly, please email kgoddard@nationalpcf.org

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