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October 7, 2025 25 mins

Today, Ivelisse welcomes Dr. Francisco Contreras, renowned surgical oncologist and Director, President, and Chairman of Oasis of Hope Hospital. Together, they dive into the world of integrative cancer care with a special focus on ozone therapy—a treatment that improves oxygenation, supports immune function, and works alongside conventional therapies to enhance healing outcomes.

Dr. Contreras shares how ozone therapy is administered, its unique benefits, and compelling patient success stories that highlight its role in strengthening the body during cancer treatment. He also opens up about the broader philosophy of Oasis of Hope, which bridges conventional and complementary medicine to provide individualized and compassionate cancer care.

Beyond the science, Dr. Contreras emphasizes the surprising yet critical connection between happiness and health, and he and Ivelisse explore how cultivating joy can impact recovery. The conversation also touches on the limitations of traditional U.S. cancer treatments and how Oasis of Hope offers a more holistic, patient-centered path.

Listeners will walk away with practical insights into how ozone therapy can boost healing, strengthen the immune system, and fit into a broader integrative approach to cancer care.


Learn more about Dr. Francisco Contreras and Oasis of Hope:

https://www.oasisofhope.com/


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Transcript

Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Ivelisse Page (00:06):
Hi, I am Ivelisse Page and thanks for listening to
the Believe Big podcast, theshow where we take deep dive
into your healing with healthexperts, integrative
practitioners, biblical faithleaders, and cancer thrivers
from around the globe.

(00:34):
Welcome to today's episode onthe Believe Big podcast.
My name is Ivelisse Page and Iam so thankful to spend this
time with you.
Today, on the Believe Bigpodcast, we are thrilled to have
as our guest, Dr.
Francisco Contreras of Oasis ofHope.
Dr.
Contreras serves as Director,President, and Chairman of Oasis

(00:57):
of Hope Hospital.
A distinguished surgicaloncologist, he is renowned for
combining conventional andalternative medical treatments
with emotional and spiritualsupport to provide patients with
the most positive treatmentexperience possible.
After graduating from medicalschool, Dr.
Contreras specialized insurgical oncology at the

(01:20):
University of Vienna in Austria,where he graduated with honors.
Dr.
Contreras has authored 15 books,amazing, concerning integrative
therapy.
In addition to writing formedical journals, he has also
participated in medicalconferences around the world.
Welcome to the podcast, Dr.

(01:40):
Contreras.

Dr. Francisco Contreras (01:41):
Thank you very much.
It's my honor and pleasure.

Ivelisse Page (01:44):
Aw.
Well, we always like to startthe episode on what our guest
favorite health tip is.
Do you have one that you canshare with us?

Dr. Francisco Contreras (01:52):
Yes, and I think it's gonna be a
little bit surprising.
My, my health tip is to doeverything possible to be happy,
a happy heart.
The Bible says a merry heart isa cure for all.
And there's no question thatwhen we're happy, our immune
system is also happy andprotects us more.
There, there are some studiesthat show that comedians, for

(02:14):
instance, live longer and betterthan anybody else.
And I, if you read about theBlue Zones, the most common
denominating factor for themliving long is because they are
gregarious and they're happy.
Of course diet plays a role manyother things play a role, but
the happier you are, the merrieryou are, the better you're going

(02:37):
to fare and being happy reallyis, it's like it is a decision,
you know, you can be happy inwhatever circumstance.
Because you choose to be happy.
And so that's my tip of the day.

Ivelisse Page (02:49):
I love that.
And I could not agree with youmore.
And I saw it actually firsthandwhen I was battling cancer.
I put it on my list to watch cocomedies.
I unplugged from the news.
I did things that brought melife, that made me laugh.
And spending time with family,things that bring you joy, you
know, like you're saying,reading scripture, all those

(03:10):
things really bring you life.
So I agree a hundred percent.

Dr. Francisco Contreras (03:14):
Amen.
Good.

Ivelisse Page (03:16):
So today we're gonna be talking about ozone
therapy, and for those who maynot be familiar, can you explain
what ozone therapy is and how itworks in the body?

Dr. Francisco Contreras (03:27):
Yes.
Ozone is a gas that is veryunstable.
In comparison to oxygen, forinstance, oxygen is O2, ozone is
O3 or more.
And thus it's quite unstable andit releases O2 into the body,
especially the bloodstream, youcan put ozone directly into the
bloodstream but most of us willwill draw blood from the

(03:50):
patient, ozonate the blood, andthen give it back.
You can also do eboo, which is amachine where it has a filter,
and you can also need a muchhigher amount of blood.
You can also use solutions, forinstance, saline solution.
That you can ozonate and give itto the patient.
You can use ozone topically.

(04:12):
Ozone is very irritating to theairway, so it's not a good idea
to breathe ozone.
So there are some bags that youcan, for instance, put it over a
foot.
A patient that, that has a didiabetic ulcers that's another
way you can use ozone intrarectally or intravaginally.

(04:33):
So there are many ways that youcan use ozone and the purpose is
to increase the amount of oxygencirculating in your body.
So, for instance, we did a studyhere where the normal
concentration of oxygen in yourbloodstream is about 99% to a
hundred.
And after a treatment of ozone,it went up by 700%.

Ivelisse Page (04:56):
Wow.

Dr. Francisco Contreras (04:56):
And this is very beneficial for many
things because lack of oxygen isone of the main reasons why our
tissues will suffer duringdisease.
And so it's used for manypurposes.
There are, for instance clinicsin Russia where they treat
everything with ozone, diabetesarthritis, everything they treat

(05:18):
with ozone.
I think that's a bit too much.
But but they have success and Ivisited them.
So ozone, the purpose of ozoneis to increase significantly the
amount of oxygen circulating,and it depends on what you're
using it for.
So for cancer, for instance themain reason we use it is to
increase the amount of oxygenwithin the tumor tissue.

(05:41):
And you can do aerobic exercise.
You can breathe oxygen directly,a hundred percent, and the
oxygen concentration within thetumor will not change.
But if you use ozone, it willincrease and that damages the
tumor.
And is very good because most,the most effective anti-tumor

(06:02):
therapies are oxidative innature, and you cannot have
oxidation without oxygen.
And that's why tumors willprotect themselves from
radiation or chemotherapy ornatural anti-tumor agents
because there's no oxygen, andthen there's no oxidation.
So at our hospital, we use ozonevery much for the purpose of

(06:28):
oxygenating tumor tissue.

Ivelisse Page (06:29):
Fascinating.
Now, So are there any particulartypes or stages of cancer where
you've found ozone therapy to beespecially helpful?

Dr. Francisco Contreras (06:40):
Well, definitely in stage four is
where we need a lot more oxygenwithin tumor tissue because
there's gonna be a lot moretumor tissue in that patient.
But you can use those on at anystage, even in early stages, it
would be beneficial.

Ivelisse Page (06:57):
Okay.
And how does it strengthen theimmune system and, you know, why
is it so crucial for someonebattling cancer?

Dr. Francisco Contreras (07:04):
Well, the immune system is everything.
In fact, it is well known, orit's an open secret that
patients that have an immunesystem working a hundred
percent, they will not developcancer.
So working for the immune systemis to me the most important
thing.
And that's why at the Oasis ofHope our immunotherapy, which is

(07:26):
called Impact, is probably themost important part of the
therapy where we specificallydevelop a therapy that the
immune system is going to attackthe patient's tumor.
And so, anything that will helpthe immune system is good and it
is well established that becauseof all of that oxygenation in

(07:47):
all of the tissues, that theimmune system is going to be
positively impacted when you useozone therapy.
That's one.
Second, it has a detoxifyingeffect.
And the less toxins you have,the less distracted the immune
system is going to be, and thusit, it works as an immune

(08:07):
simulating agent.

Ivelisse Page (08:09):
I love that.
So how do you integrate ozonetherapy alongside immunotherapy
treatments or conventionaltreatments at Oasis of Hope,
like chemo, radiation, surgery,all those things?

Dr. Francisco Contreras (08:21):
Well, as I mentioned to you because
the main therapies are thetherapies that are the most
effective in killing tumortissue are oxidative.
And so there are somechemotherapies that are
oxidative, all radiation isoxidative.
But the one that we use the mosthere is high dose vitamin C.
And vitamin C, you know,interestingly it's known as the

(08:43):
most effective antioxidant in,in nature, but in very high
dosages it converts into anoxidant within the tumor.
And so if you have oxygen withinthe tumor and high dosages of
vitamin C, you actually convertthe vitamin C into a

(09:05):
chemotherapy with no sideeffects.
And so that is one of the mainpurposes why we use ozone in our
hospital, to increase the amountof oxygen so that we can have
oxidative stress.
It can also be used incombination with chemotherapy,
with some, not allchemotherapies are oxidative.

(09:26):
But with radiation, there arestudies that show that patients
that do ozone therapy beforeradiation will have better
outcomes.
But here we use it incombination with vitamin C,
mainly with very good results.

Ivelisse Page (09:40):
That's great.
So, you know, a lot of thingshave risks versus the benefits
of them.
So, are there any risks ofinteraction between ozone
therapy and traditional othertraditional cancer treatments
that patients and caregiversshould be aware of?

Dr. Francisco Contreras (09:55):
There's very little contraindications
for the use of ozone incombination with just about any
therapy in the treatment ofcancer.
And we've been using ozone herefor 30 years in high dosages
with very good results andvirtually no complications.

Ivelisse Page (10:17):
So you've been practicing oncology for many
decades at Oasis of Hope, andhow have you seen the role of
therapies like ozone evolve inintegrative cancer care over the
years?

Dr. Francisco Contreras (10:29):
Well, there's been a lot of
developments and there's newmachinery.
For instance, the EBOO is fairlynew and so you are able to
ozonate a lot more blood thanwith the auto hemotherapy, which
has been used for many years.
Also, the equipment and devicesto ozonate are more effective

(10:52):
using this oxygen, and they willalso release a lot less ozone
into the atmosphere.
So there's been a lot ofdevelopments, especially from
the Germans in the equipmentthat is now used.
And I'm very happy for that.
Also, I think that a lot moredoctors that are in the

(11:12):
alternative realm are aware ofthis and more and more doctors
are using ozone now than anytimethat I can remember in the past.
And some conventionalradiotherapists will recommend
either ozone or hyperbaricchamber to patients that are
going to undergo radiationtherapy.

(11:33):
And so those developments arevery positive.

Ivelisse Page (11:37):
That's great.
Yes.
I've heard the same I've heardthat as well from both worlds,
both the conventional and thecomplementary cancer side.
In your book, the Art of Scienceof Undermining Cancer, you talk
about empowering the body'snatural defenses.
How does ozone therapy alignwith this philosophy?

Dr. Francisco Contreras (11:58):
Well, as I mentioned before if you can
get somebody's immune system towork a hundred percent, the
cancer is going to be destroyed.
And so ozone is a big part ofour therapy, not only because it
helps in allowing vitamin C tobe very a very effective
anti-tumor agent, but alsobecause the oxygenation is going

(12:19):
to, as I mentioned before, isgoing to improve the quality and
quantity of, of our defenses.
And without that, even if youget rid of the tumor, that's the
major problem with radiation andchemotherapy.
They can destroy a tumor, butthey also destroy the immune
system.
And even a couple of cells thatare left behind are going to

(12:40):
come back with a vengeance.
So, doing a therapy that at thesame time that it destroys the
tumor, improves the quality ofthe immune system is a, it is
just a major blessing.
And that's why I believe that wehave much better results here
than in, in many other cancercenters because we're always

(13:00):
working for the immune system,not just against the tumor.

Ivelisse Page (13:05):
Yes.
In your experience, what hasbeen one of the most profound or
surprising patient outcomes thatyou've witnessed involving ozone
therapy?

Dr. Francisco Contreras (13:16):
Oh, wow.
We have so many miracles here.
But with, specifically withozone therapy, we have a number
of patients that are diabetic atthe same time.
And when we use ozone therapy.
Their ulcers are going to beresolved, but using ozone

(13:36):
topically in a cream it, it's alittle bit difficult to create
these creams, but most peoplethat do this is with with olive
oil or other oils where theyozonate these oils and the ozone
is actually gonna be trappedthere.
And so they can stay there for along time.

(13:57):
And using these topical creamscan be very helpful for
ulcerated tumors.
And this happens a lot withbreast cancer when it's very
advanced.
And the results of helping womenwith these ulcerated breast
tumors that are very irritating,very painful.
Patients lose their possibilityof social life because they're

(14:21):
very smelly.
Just with a couple of days oftreatment, the odor goes away,
the bleeding goes away, and thetumors start receding.
So the topical use of ozone incases like this are a blessing
to many people with ulceratedtumors.
And it's very impressive that insuch a short time you can get

(14:44):
those results.
So those are.
That's what comes to mind when Ithink of ozone as helping
somebody in dire need of help.

Ivelisse Page (14:53):
Yeah.
And I haven't heard of it in theform of creams.
That's fascinating.
Is that something that aphysician would have to
prescribe or are there placeswhere you can buy?

Dr. Francisco Contreras (15:02):
No, i'm pretty sure that you could find
ozone cream on the web.
Nowadays you can find just abouteverything.
We have a source in, in, inCanada that produces a very high
quality ozone cream.
We call it cream.
It's more than an oil than acream.
And you have to keep it cold sothat it solidifies.
If you don't, it is going to gointo a very messy oily

(15:26):
substance.
But I'm sure that you can findthat on the internet and yeah,
you send, if you have any typeof ulcerated problem, even if
it's not cancerous, it's gonnahelp a lot for diabetic foot or
ulcers or people that have verypoor circulation.
It's a, it is really miraculous.

Ivelisse Page (15:47):
Yeah.
If you don't mind sending thename of that after our episode,
we can add it in the show notes.

Dr. Francisco Contreras (15:52):
I'll ask our son to give it to you
because we buy it in bulk.
Okay.
I don't remember the, if it hasa commercial name or not.

Ivelisse Page (15:58):
Okay.
Fantastic.
And so what are some commonmethods of administering ozone
therapy and how do you decidewhich approach best suits a
patient's individual case?

Dr. Francisco Contreras (16:11):
Okay, so I mentioned, you know, the
most common ones the one that weuse here the most is
autohemotherapy or the EBOO,where you also need blood that,
that you give back to thepatient.

Ivelisse Page (16:24):
And I'm sorry, before you move on, a lot of
people have never heard EBOO.
Can you just really quicklyshare what EBOO is and how that
works?

Dr. Francisco Contreras (16:32):
So, EBOO is a device that has a
filter very similar tohemodialysis.
And so we connect the patient tothis device where it draws the
blood from one vein goes throughthe system, it's ozonated in
this system, and then goes backinto the patient in another

(16:55):
vein.
So it's a more involved medicaldevice.
This is something that you haveto do in a clinical setting that
you usually cannot do at home,and that's what EBOO is.

Ivelisse Page (17:10):
Okay.

Dr. Francisco Contreras (17:12):
Then then you have the topical, as I
mentioned to you, but also arebags where you can put a whole
limb into the patient or you cancover the breast, for instance,
of a patient with these bags andactually ozonate them with the
gas itself.
And the reason you do that as Imentioned before, is that ozone

(17:35):
is very irritating to theairways, so you shouldn't
breathe ozone.
Because again, it's gonna bevery irritating.
There is the intravaginal andintra rectal for patients that
have tumors in the abdomen, forinstance, or that have such poor
veins that you cannot do theEBOO or the autohemotherapy Then

(18:00):
we can insert a probe into thevagina or into the rectum, and
then the ozone is going to beabsorbed through the abdomen to
the bloodstream.
And so the amount of oxygen isgoing to increase, not as much
as with the blood that you canozonate, but it's a good enough

(18:21):
possibility.
And the other one is ozonatingsolutions like a saline
solution.
This is convenient because youdon't, many patients are anemic
and you, it is just complicated.
Also for patients that areJehovah's Witness, for instance,
they have problems sometimeswith anything that has to do

(18:43):
with the blood.
Although these elements areusually accepted.
The EBOO and the autohemotherapy is accepted by the
community because it's the sameloop and the blood comes back to
the patient.
And so, we've contacted medicalpeople from the Jehovah's
Witness community that willadvise patients that is

(19:06):
something that is kosher forthem to do.

Ivelisse Page (19:09):
That's great.
That's really fascinating.
I've also heard that the ozonetherapy, as far as EBOO, has
also been used for people withlong COVID.
Have you seen that at as well?

Dr. Francisco Contreras (19:21):
Yes.
We have very little experiencewith long COVID here.
But I've heard that that peoplecan be benefited and definitely
I believe it to be true becausehigh oxygen concentration are
they kill viruses.
They kill bacteria, and so ozonehas been used, as I mentioned to

(19:41):
you in many clinics to treatinfections of any kind, so I
don't see why not it should behelpful for COVID patients.
But I have no experience withit.

Ivelisse Page (19:53):
Yeah.
Well, and I wanted to just takethe last few minutes'cause you
shared that I wanted to letpeople know as far as Oasis of
Hope, your hospital just treatscancer.
Is that correct or does it alsotreat other illnesses as well?

Dr. Francisco Contreras (20:07):
No, that is correct.
We are specialized in cancer.
We believe that many of thethings that, that we do could
help in other diseases, but weconcentrate on, on, on treating
cancer only.

Ivelisse Page (20:18):
So if individuals wanted to, you know, I believe
Gaston who is part of your teamat Oasis of Hope said that I
believe 75% of the patients cometo you from the United States to
get treatment because there arethings that you can do there
that can't really be done in theUnited States.
And so what are some of thosethings that you find, because at

(20:41):
your hospital, you do it all,correct?
There's, you have the ability todo surgery.
Explain a little bit about Oasisof Hope so people become
familiar with it.

Dr. Francisco Contreras (20:50):
So we were founded by my father in
1963.
So we've been doing this for along time.
I've been the director of theOasis of Hope now for nearly 40
years following on my dad'sfootsteps.
And we are an integrativeoncological center.
So we are going to offer ourpatients whatever we feel is the

(21:11):
best for them according to theirstage and condition.
And so we have everythingavailable, all of the
conventional we have available,and just about everything in the
alternative realm.
We also have available and inmany cases it's a combination of
the two of them that, that wefeel that is the best for, for

(21:32):
our patients.
So, I think that the advantagethat we have here is that you
know, I've been asked before,well, what is it?
Are you an alternative doctor ora conventional doctor?
And what type of medicine do youdo the conventional or
alternative?
I said I just want to do goodmedicine and I'll choose from
whatever part of, of the realmto improve the quality of life

(21:56):
of my patients and the, andtheir longevity.
So, we have everything availablehere at the Oasis of Hope.

Ivelisse Page (22:03):
Yeah, that is wonderful.
And I hope that one day theUnited States can follow suit.
And I think what a lot of peopledon't understand is that even
though a conventional oncologisthere in the United States
believe in some of the therapiesthat we've talked about on this
podcast, many of them can'tprescribe it or share it with
their patients because it's notpart of standard of care here in

(22:25):
the United States.
They can only prescribe chemo,radiation, and surgery.

Dr. Francisco Contreras (22:30):
And one of the things that is very
puzzling is that we are using,for instance, therapies that
were designed and developed inAmerica that they cannot use.
For instance, our impactprotocol, our dendritic cell
vaccine, our dendritic cellbased immunotherapy was all
developed in America.

(22:51):
In fact the developers obtainedNobel Prizes for it.
It's not available in America,and it is available in Mexico.
In, in, from there, there aresome alternatives.
For instance, vitamin C was alsodeveloped at the NIH and NCI.
It's still not available forpatients.
So patients from America have tocome to Mexico to obtain those

(23:13):
therapies that are veryeffective and non-toxic, and
they come to Mexico.
There are then other elementsfor instance, LAtrol that has
been approved in Mexico, but notapproved in America.
And so, and in many parts of theworld.
So the other seven, the other25% come from the rest of the
world.
We have patients, we've treatedpatients from over 50 countries

(23:35):
and they come here becausethey're available in Mexico and
not available in theircountries.

Ivelisse Page (23:40):
Yeah.
And we're hoping at Believe Bigthat one day we can help to
change that kind of how we'reworking with Johns Hopkins right
now to complete all three phasesof the Mistletoe clinical trial.
And so hopefully more of thesetherapies like, you know,
mistletoe therapy like IVvitamin C, can be used in the
conventional settings morefrequently than they currently

(24:01):
are.
Dr.
Contreras I loved speaking withyou today and I would love to
invite you back because you, Idid hear you at a conference
speak about the Dendritic Cellsvaccine, and I think it was a,
it was one of my favorite talksthat I heard that weekend, and I
know it would need a completeepisode to talk about it, so I
would love to invite you back.

Dr. Francisco Contre (24:21):
Wonderful.
I'd love to do that.
Yes.

Ivelisse Page (24:23):
Well, great.
Well, thank you for joining us.
I know that your time is sovaluable and look forward to
talking to you soon.

Dr. Francisco Contreras (24:29):
Thank you very much.
God bless.

Ivelisse Page (24:31):
God bless.
If you enjoyed this episode andyou'd like to help support our
podcast, please subscribe andshare it with others.
Be sure to visit believebig.orgto access the show notes and
discover our bonus content.

(24:51):
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