In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alfred Botchway, CEO of Attentive Science, to discuss his journey in biomedical science and the groundbreaking work being done at the intersection of AI, non-clinical safety, and drug discovery. Dr. Botchway shares his insights on the role of AI in refining toxicology studies, how stress impacts human health, and his experience founding companies like Xenometrics and Attentive Science.
The conversation dives deep into the complexities of Good Laboratory Practices (GLP), the importance of regulatory standards, and the exciting research happening in anxiety and PTSD treatments. Dr. Botchway also discusses the future of biomedical research, the need for greater collaboration between academia and industry, and how innovations in sample collection are transforming clinical trials.
Whether you’re interested in AI, biomedical innovation, or the future of drug discovery, this episode offers valuable insights from a leader shaping the industry.
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Dr. Alfred Botchway
https://www.linkedin.com/in/alfred-botchway-41b01a6/
CEO of Attentive Science: https://www.attentivescience.com/
Dr. Chad Briscoe
https://www.linkedin.com/in/chadbriscoe/
Celerion - https://www.celerion.com/
Gregory Austin
https://www.linkedin.com/in/gregoryaustin1/
Celerion - https://www.celerion.com/
00:00 Introduction to BioTalk Unzipped
02:32 Dr. Alfred Botchway's Journey in Biomedical Science
03:48 Challenges Founding and Growing Xenometrics
07:30 Starting Attentive Science: A New Venture
09:37 Love of the Work - Variations
10:26 The Role of AI in Non-Clinical Safety Assessments
13:04 The Three Rs: Replace, Reduce, Refine, and AI
15:46 Regulatory Standards and Good Laboratory Practices
20:42 New News! - Research on Anxiety and Drug Discovery
27:07 Cortical Stimulation and Stress Management
27:45 Bridging Academia and Industry
29:26 Engaging the Next Generation in Science
32:42 The Value of Vocational Training in Science
34:47 Community Involvement and Giving Back
37:00 Cultural Influences on Leadership
42:39 Global Expansion and Strategic Goals
48:41 Innovations in Sample Collection for Clinical Trials
Digital Twin Episodes reference with Tomas Helikar:
Transforming Immunology: The Promise of Digital Twins with Dr. Tomáš Helikar
https://youtu.be/jTM_Zlt3wxU
Digital Twins: The Future of Drug Discovery with Dr. Tomáš Helikar
https://youtu.be/NM5X0jTd6UA
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