This episode of the podcast is the launch of an educational series with Arizona NORML and Nick Gasman with CannaEd. In this episode we discusss the medicinal benefits of a plant based medicine. This episode is meant to assist beginners in some explanations into the cannabis world. We cannot possibly cover everything but can provide an introduction. For further information, follow the shownote links provided. (Apologies for the camera light, the sensor was going crazy).
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The information, including but not limited to, text, graphics, images and other material contained on this podcast are for infomrational purposes only and we are relying on the fair use exception regarding their usage. No material on this podcast is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding medical conditions or treament. Never disregard professional medical advice or delay in seeking care because of something you heard or saw on this podcast.
The Endocannabinoid System
We want to convey to the audience about the correlation to various health benefits and stimulating the endocannabinoid system. We want to use data to assure that these benefits are indeed coming from cannabis and are not a placebo effect.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834283
“Upregulation of cannabinoid receptors is also observed in the spinal cord following nerve injury [150, 163], suggesting that both endocannabinoids and their receptors are regulated under conditions of injury”
The Entourage Effect
We want to highlight the importance of terpenes as well as cannabinoids other than THC when consuming cannabis.
https://www.marijuanamoment.net/marijuana-entourage-effect-with-multiple-cannabinoids-produces-a-stronger-and-longer-lasting-high-than-pure-thc-study-finds/#:~:textBut%20a%20new%20study%20is,generated%20by%20pure%20THC%20products.
“a new study is supporting the “entourage effect” theory, finding that cannabis products with a more diverse array of natural cannabinoids produce an even stronger psychoactive experience that lasts longer than the high generated by pure THC products.”
The study utilized novel electroencephalog in ram (EEG) technology supported by AI to quantify the “high” people experienced when vaping two different products:1) a full-spectrum live rosin with average 85 percent THC as well as other natural cannabinoids and terpenes, and 2) a high purity THC oil with 82-85 percent potency. A total of 28 adults participated in the study, strapping on the EEG headset developed by the cannabis technology company Zentrela and taking two hits (8 mg) of either the full-spectrum or pure THC varieties from a vape manufactured by PAX, which also supported the study. After getting a baseline reading before the participants consumed the products, the EEG monitored activity in eight regions of the brain over the course of 90 minutes. The tests were then converted into “psychoactive effect levels (PEL) in a standardized scale from zero percent to 100 percent.” The results showed that the full-spectrum live rosin with THC and other cannabinoids and terpenes had a slightly earlier onset of three minutes, a higher potency reading for the onset (20.8 percent) and higher potency at the peak after 15 minutes (40 percent) and after 90 minutes (30.2 percent).The pure THC product’s average onset was four minutes, with potency at 13.5 percent. At the peak, the potency was 19.1 percent, and that dropped slightly to 18.1 percent.
Edible Ingestion (11-Hydroxy THC)
Details: We want to educate our audience on the difference between THC & 11-Hydroxy THC, and why we as consumers should be cautious when dosing edibles.
Data:
https://encorelabs.com/11-hydroxy-thc-why-edibles-can-feel-more-potent/
https://pubmed.ncbi.nlm.nih.gov/4729039/