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November 12, 2025 29 mins
In this episode of Cutaneous Miscellaneous, host Nicholas Brownstone, MD, welcomes Shannon Trotter, DO, for a discussion on photodynamic therapy (PDT), a treatment many residents may receive limited exposure to during training. Dr Trotter shares how PDT fits into both preparing for board exams and clinical use, highlighting its versatility and importance in dermatology. They open with a board review of PDT fundamentals, including the activation of aminolevulinic acid (blue light) and methyl aminolevulinate (red light), and why understanding protoporphyrin IX and its absorption spectrum matters. They also cover key uses along with adverse effects such as phototoxicity and pigment alteration. In the main segment, they explore actinic keratosis as a chronic disease, the importance of field therapy, and how to set expectations. Dr Trotter also shares practical pearls for optimizing outcomes and tailoring PDT in clinic. Tune in to hear how Dr Trotter integrates PDT into daily practice and empowers residents to expand beyond traditional training to confidently incorporate this helpful therapy.
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