Daily Value

Daily Value

Daily Value is a podcast that takes a deep dive into essential nutrients and dietary practices that fuel our bodies and minds. Hosted by Dr. William Wallace, a leading product developer in the Natural Health Product industry and a dedicated educator in health and nutrition, this show is your go-to resource for understanding the science behind the vitamins, minerals, and supplements that influence human health. Each short, digestible episode unpacks the latest scientific findings, protocols, and insights into how specific nutrients contribute to overall well-being. Whether you're a health professional, nutrition enthusiast, or just curious about how what you consume affects your health, Daily Value offers evidence-based discussions to help you make informed decisions for a healthier life. Join Dr. Wallace as he shares his expertise, developed from years of experience in product development and nutrition science, to advance your knowledge and awareness of dietary interventions for optimal health. Get your daily value and add meaningful insights to your day, one episode at a time. DISCLAIMER: William Wallace holds a Ph.D. He is not a medical doctor. Content generated for this channel is strictly for educational purposes and does not constitute medical advice. The content of this channel is not meant to substitute for standard medical advice, diagnosis, or treatment. Please consult with your primary healthcare practitioner before beginning any nutrition-, or supplement-based protocols. This is especially important if you are under the age of 18, undergoing treatment for a medical condition, or if you are pregnant or nursing.

Episodes

May 19, 2025 11 mins

Debunking Myths: The safety and side effects of creatine supplementation. In this episode of Daily Value we look into the safety concerns surrounding creatine supplementation. Creatine, a well-researched dietary supplement known for its muscle-building and performance-enhancing benefits, has sparked numerous myths about its effects on kidneys, hair loss, and dehydration. We will evaluate recent studies and scientific evidence to ad...

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In this episode of Daily Value, we look at a forgotten compound found in common vegetables such as kale, spinach, and broccoli. Discovered in the 1930s and initially thought to be a vitamin (dubbed “Vitamin P”), this compound has recently demonstrated significant potential in neuroprotection.

This compound may soon become an essential component in neuroprotective and longevity formulations.

00:00 Introduction to Brain Health Molecule...

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In this episode of Daily Value, we look at newer research on melatonin that challenges conventional wisdom. A recent meta‐analysis questions current clinical guidelines on melatonin use for sleep, suggesting there may be a dual (Dose X Time effect) secret to optimizing its effects. We’ll break down the scientific clues behind optimal dosing, timing, and formulation, leaving you to wonder if you've been taking melatonin all wro...

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In this episode of Daily Value, we look at the latest research on B vitamins and their in neuropsychiatric disorders. A newly published meta-analysis suggests a causal relationship between B vitamin deficiencies and neuropsychiatric disorders. We will break down the scientific findings on B6, B12, and folate, shedding light on their roles in conditions like Parkinson’s disease.

Discussion Points:

  • How recent genetic studies suppor...
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February 12, 2025 10 mins

 In today’s episode of Daily Value, we explore the possibly underappreciated role of vitamin K in brain health and neuroprotection. Recent research (doi: 10.3389/fnut.2024.1396707) reveals a connection between dietary vitamin K intake and reduced levels of neurofilament light chain, a potential biomarker for neurodegeneration, particularly in middle-aged and older adults. We’ll discuss how vitamin K supports neuronal function, what...

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In this episode of Daily Value, we look at the emerging research on creatine supplementation in women’s health—beyond its well-established role in exercise performance. With evidence mounting on creatine’s impact across menstruation, pregnancy, postpartum recovery, and menopause, we discuss how it supports cognition, mood stabilization, and bone health throughout a woman’s lifespan.

Discussion Points:

  • Creatine & Hormonal Fluc...
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In today’s episode of Daily Value, we take a closer look at a commonly overlooked but essential nutrient: vitamin B12. Known as cobalamin, vitamin B12 deficiency can lead to severe neurological, hematological, and cognitive issues if left unchecked. We’ll cover the causes behind this growing issue, from dietary intake to malabsorption.

Episode Talking Points:

  • The role of B12 in nervous system function and red blood cell productio...
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In this episode of Daily Value, we look at how paternal alcohol consumption before conception could influence offspring health, longevity, and even accelerate aging. Referencing studies from Andrology (PMID: 38044754) and Aging and Disease (PMID: 39122451), we examine how sperm RNA modifications and mitochondrial dysfunction may persist long after alcohol cessation—potentially programming offspring for metabolic disorders, reduced ...

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In this episode of Daily Value, we explore the potential of omega-3 fatty acids, particularly EPA and DHA, as an adjunctive therapy for reducing anxiety symptoms. A recent meta-analysis (PMID: 38890670) reviewed 23 randomized controlled trials involving over 2,100 participants, revealing that a certain amount of omega-3s per day can significantly reduce anxiety symptoms, especially when combined with traditional treatments like ant...

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In this episode of Daily Value, we look at how extra virgin olive oil and its polyphenols—including hydroxytyrosol—could impact your health and longevity. Referencing evidence from the Moli-Sani Study and other meta-analyses (PMID: 38704428), we uncover how these bioactives are suggested to reduce risks for cancer, cardiovascular disease, and all-cause mortality.

Discussion Points:

  • Bioactive Compounds: How hydroxytyrosol prevents...
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In this episode of Daily Value, we look at how the roasting style of coffee—light versus regular—might influence body composition. Examining evidence from a recent randomized controlled trial published in Nutrients (PMID: 39275165). Could your choice of coffee enhance fat loss and muscle mass?

Discussion Points:

  • Roasting and Polyphenols: How lightly roasted coffee, with higher chlorogenic acid content, outperformed regular roasts...
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In this episode of Daily Value, we explore the recent findings on the role of B-group vitamins as potential prebiotic candidates and their effects on the human gut microbiome. The discussion is centered around some of the latest research, which highlights how these essential vitamins, traditionally known for their metabolic roles, are now being recognized for their ability to modulate the gut microbiome and how different bacterial ...

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January 22, 2025 9 mins

In this episode of Daily Value, we look at the relationship between genetics, habitual caffeine intake, and cognitive performance, using insights from a recent study (PMID: 39648354) in the Journal of Psychopharmacology. Whether you’re a "fast" or "slow" caffeine metabolizer could significantly influence how caffeine impacts your brain.

Discussion Points:

  • Gene-Caffeine Interactions: how variants in CYP1A2 and ...
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 Does green tea protect the aging brain better than coffee? In this episode of Daily Value, we look at the evidence behind green tea's impact on brain aging, focusing on cerebral white matter lesions, Alzheimer’s risk, and brain atrophy. Drawing on studies like Shibata et al.'s recent publication in Science of Food (PMID: 39774601), we discuss how a certain threshold of green tea, but not coffee is associated with less wh...

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In this episode of Daily Value, we look at the role of maternal Vitamin B12 intake during pregnancy and its impact on a child’s IQ. Drawing on findings from the ELSPAC study (PMID: 39674678), we discuss how Vitamin B12 supports critical neurodevelopmental processes and how deficiency may impact verbal IQ.

Discussion Points:

  • The role of Vitamin B12 in one-carbon metabolism, axon myelination, and DNA methylation, and their importan...
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How much coffee is too much? In this episode of Daily Value, we look at the link between coffee consumption and cognitive health. Drawing on a recent study published in the Journal of the American Heart Association (PMID: 39673298), we examine how bioactive compounds in coffee, such as chlorogenic acids and trigonelline, may protect against cognitive decline and inflammation.

Discussion Points:

  • Insights from the Swiss Atrial Fibr...
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In this episode of Daily Value, we take a look at how fiber fuels anti-cancer gene activity - emphasizing the role of short-chain fatty acids (SCFAs) produced during fiber fermentation. Drawing on new research PMID: 39789354) published in Nature Metabolism out of Stanford Medicine, we examine how fiber-derived metabolites influence gene activity to reduce cancer risk and promote overall health.

Discussion Points:

  • The epigenetic r...
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In this episode of Daily Value, we look into the synergistic relationship between two nutrient classes in supporting brain health and mitigating cognitive decline. Drawing on evidence from past clinical evidence suggesting these two nutrient classes work in tandem to support brain function and health.

Discussion Points:
-Homocysteine’s role in disrupting fatty acid incorporation into cell membranes and amyloid-beta cle...

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 In this episode of Daily Value, we examine the latest research on wine consumption and its relationship to cardiovascular health. Leveraging urinary tartaric acid as an objective biomarker, a recent study (PMID: 39689849) published in the European Heart Journal provides interesting evidence of a J-shaped association between wine intake and cardiovascular outcomes.

Discussion Points:

  • Biomarkers and Bias: The role of urinary tarta...
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In this episode of Daily Value, we look at science of Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR), two NAD+ precursors gaining traction in longevity research. Both supplements aim to restore NAD+ levels, critical for energy metabolism and cellular repair, yet their distinct pathways and tissue-specific effects suggest considerations for choosing one over the other.

Discussion Points:

-The metabolic pathways of NM...

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