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September 25, 2025 21 mins
With Dr. McCoy to guide us, we go deep into the real-world challenges of diagnosing Sjogren’s—getting expert advice on how to overcome them. We share practical, in-clinic strategies for distinguishing Sjogren’s from other causes of dryness, explore the pitfalls of seronegative cases, and reveal why certain tests and interpretations can make or break an accurate diagnosis. About Dr. Sarah McCoy Dr. McCoy is a rheumatologist, physician scientist, and Director of the University of Wisconsin Sjogren’s Clinic. She has specialized expertise in labial salivary gland biopsies, musculoskeletal and glandular ultrasound, and the nuanced clinical evaluation of Sjogren’s. In this episode, we explore: (00:00) Sjogren's Disease: diagnostics and treatment challenges (05:47) Evaluating dryness in Sjogren’s diagnosis (07:45) Sjogren’s mimics, including infections, sarcoidosis, and IgG4-related disease. (09:22) Sjogren's Disease evaluation process and objective testing from the office and clinic (11:59) Imaging techniques for salivary gland diagnosis (16:19) If you take one thing from this episode... Learn more about your ad choices. Visit podcastchoices.com/adchoices
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