Decoding Sjogren’s Disease: A Clinical Deep Dive – Season 2

Decoding Sjogren’s Disease: A Clinical Deep Dive – Season 2

Building on an award-winning first season, Decoding Sjogren’s Disease: Season 2 answers the tough question: What happens after diagnosis? Phenotyping, biomarker surveillance, biologic candidacy, treatment timing — most clinicians are still making decisions with scores that were never built to guide treatment. Over five new episodes, the world’s leading Sjogren’s experts offer a masterclass on the mechanistic drivers, tracking tools, and precision medicine strategies defining the next era of Sjogren’s therapy. The standard of care for this disease is about to meaningfully shift. Is your practice keeping up? This content is intended for medical professionals only.

Episodes

August 26, 2026 18 mins
Sjogren's has long been reduced to its most visible symptoms, but the biology tells a more complex story. In this episode, Dr. Nancy Carteron walks through the immune mechanisms driving Sjogren's from the inside out, including the interplay between Type I interferon signaling and B-cell hyperactivity, how germinal center structures in the salivary glands fuel ongoing autoimmunity, and why BAFF dysregulation may be a critical and un...
Listen
Watch
Mark as Played
In this episode, Dr. Teja Kapoor unpacks why a single disease activity score tells only half the story, how to phenotype patients into actionable clinical categories, and which biomarkers should be on your radar before symptoms ever surface. If you rely on uniform monitoring schedules, this conversation will change how you think about follow-up. About Dr. Teja Kapoor Dr. Kapoor is the Director of the Columbia Sjögren’s Ce...
Listen
Watch
Mark as Played
When the disease is active but the patient feels fine, or the symptoms are overwhelming but the labs look quiet, standard protocols start to break down. This episode gets concrete about what precision Sjögren's care actually looks like at the bedside. Dr. Teja Kapoor walks through how to translate EULAR disease activity thresholds into individual treatment goals, when the case for off-label biologic therapy genuinely builds, and wh...
Listen
Watch
Mark as Played
August 26, 2026 15 mins
In this episode, Dr. Chadwick Johr of the Penn Sjögren Center walks through how he evaluates organ involvement, B-cell activity, and lymphoma risk to decide when to escalate treatment. He also unpacks why early anti-CD20 trials appeared to fail, what composite endpoints like CRESS revealed, and why the next wave of targeted therapies has him genuinely optimistic about the future of Sjögren's care. About Dr. Chadwick Johr Dr. Jo...
Listen
Watch
Mark as Played
August 26, 2026 13 mins
Dr. Chadwick Johr, Director of the Penn Sjogren Center, cuts through the hype around precision medicine to assess where the field actually stands and what it will take to move from research protocols into real clinical decisions. He unpacks why Sjogren's resists a one-size-fits-all treatment approach, how salivary gland biopsy and interferon signatures are beginning to stratify patients in meaningful ways, and what the next decade ...
Listen
Watch
Mark as Played

Popular Podcasts

    If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

    Betrayal Weekly

    Betrayal Weekly is back for a new season. Every Thursday, Betrayal Weekly shares first-hand accounts of broken trust, shocking deceptions, and the trail of destruction they leave behind. Hosted by Andrea Gunning, this weekly ongoing series digs into real-life stories of betrayal and the aftermath. From stories of double lives to dark discoveries, these are cautionary tales and accounts of resilience against all odds. From the producers of the critically acclaimed Betrayal series, Betrayal Weekly drops new episodes every Thursday. If you would like to share your story, you can reach out to the Betrayal Team by emailing them at betrayalpod@gmail.com and follow us on Instagram at @betrayalpod and @glasspodcasts. Please join our Substack for additional exclusive content, curated book recommendations, and community discussions. Sign up FREE by clicking this link Beyond Betrayal Substack. Join our community dedicated to truth, resilience, and healing. Your voice matters! Be a part of our Betrayal journey on Substack.

    Dateline NBC

    Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

    The Joe Rogan Experience

    The official podcast of comedian Joe Rogan.

    Love Trapped

    Former Bachelor Clayton Echard’s casual one-night fling turned into a paternity nightmare. When the news broke about the scandal, no one believed Clayton at first. He was a reality TV star, and an unpopular one at that. Clayton found himself trying to prove the truth, while trapped in a web of lies, manipulation, and threats. He would soon discover he was not the only one. At its core, this is a story about who you believe and why. It’s an epic battle that would take a group of strangers, citizen sleuths from across the world, to crack the case and finally hold someone accountable. New episodes of Love Trapped are released every Thursday, starting February 26th, 2026. If you would like to reach out to the Love Trapped team, email us at lovetrappedpod@gmail.com and follow along on Instagram @glasspodcasts.

Advertise With Us
Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2026 iHeartMedia, Inc.

  • Help
  • Privacy Policy
  • Terms of Use
  • AdChoicesAd Choices