Demystifying PANS/PANDAS Podcast

Demystifying PANS/PANDAS Podcast

Welcome to the Demystifying PANS/PANDAS Podcast with Dr. Nancy O'Hara! Ever wondered why some kids experience sudden, life-altering behavioral changes? This podcast delves into PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Strep). Experts explore the triggers, symptoms, and innovative treatments for these autoimmune disorders, blending science and heartfelt guidance. From strep to Lyme, natural therapies, emotional support, and recovery stories—this is your guide to hope and healing.

Episodes

February 25, 2026 49 mins

The most powerful tool in pediatric care may not be a test or a treatment… but presence. In this episode of Demystifying PANS/PANDAS, Dr. Larry Rosen shares how curiosity, listening, and relationship-centered care change outcomes for children with complex neuroimmune conditions, including PANS/PANDAS.

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About the Guest:

Dr. Lawrence Rosen is an integrative pediatrician and founder of the Whole Child Center, where he has suppor...

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What if one of the most commonly used childhood medications carries risks that medicine has failed to fully confront? In this episode of Demystifying PANS/PANDAS, I speak with Dr. William Parker about decades of research connecting acetaminophen exposure, susceptibility, and neurodevelopment, and why timing, metabolism, and immune stress matter more than most studies acknowledge.


One overlooked moment may explain far more about ...

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January 28, 2026 50 mins

In this episode of Demystifying PANS/PANDAS, I talk with TruDOSE leaders Tapley Holland and Elena Herning about how precision-dosed platelet therapy works to modulate immune dysfunction, calm neuroinflammation, and support healing in children and adults with complex conditions like autism and PANS/PANDAS.


When healing finally starts working, it doesn’t always look comfortable at first. In this episode of Demystifying PANS/PANDAS...

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What if the fastest way to change a child’s diet is to stop trying to take foods away? In this episode of Demystifying PANS/PANDAS, I talk to Dr. Joshua Green on integrative care for complex illness, how he helps kids with restrictive eating by focusing on 'adding' first, and why a membership-based practice can restore time, trust, and better outcomes.


What if families aren’t failing treatment, but medicine is failing to...

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Why does neuroinflammation look different as children grow? In this episode of Demystifying PANS/PANDAS, pediatric neurologist Dr. John Gaitanis explains the continuum of neuroinflammation, why regression represents loss of brain function, and how energy metabolism, immune activation, and the cell danger response shape symptoms across childhood and adolescence.


Regression isn’t loss without cause. It’s the brain conserving energ...

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Lyme disease: what if everything you know about it was only a fraction of the truth? In this episode of Demystifying PANS/PANDAS, Dr. Tom Moorcroft joins us to break down misdiagnosis, co-infections, persistence, testing pitfalls, immune dysregulation, and the mindset shifts that helped him recover after eight years of undiagnosed illness.


Most people think Lyme disease is simple—until they get it. In this episode of Demystifyin...

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December 31, 2025 48 mins

This is the mistake most protocols make with complex kids… In this episode of Demystifying PANS/PANDAS, Dr. James Neuenschwander, also known as Dr. Neu, joins us to talk about root-cause biochemistry, why there’s no one-size protocol for autism or PANS/PANDAS, and how patterns like immune dysfunction, gut issues, methylation problems, and the cell danger response can drive chronic illness.


Why complex illness refuses to follow a...

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What if you did everything right in pregnancy… and your child still developed autism and PANS/PANDAS? In this episode of Demystifying PANS/PANDAS, functional clinical nutritionist Inna Topiler joins us to talk about autoimmunity, preconception health, hidden triggers, flares, and the deep emotional work of parenting a neurologically sensitive child.


What happens when you spend years restoring your own health, and still face your...

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What happens when a ten-year-old wakes up as a completely different child, hearing voices, gripped by terror, and no one can explain why? In this episode of Demystifying PANS/PANDAS, Isabel Witkos shares her story of years of misdiagnosis, trauma, self-harm, and suicidality, and how she rebuilt her life through therapy, community, and a stubborn kind of hope.


She went to bed a typical ten-year-old and woke up terrified of her ow...

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What if your child’s sudden tics, rages, anxiety, or personality changes were signs of the immune system attacking the brain after an infection? In this episode of Demystifying PANS/PANDAS, Dr. Craig Shimasaki reveals how a simple blood test can uncover hidden immune reactions, explain the most confusing symptoms, and point families toward real answers and real healing.


If your child changed overnight, this conversation may expl...

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Leaky skin. Leaky gut. Leaky brain. The connection is real, and it’s impacting our kids. In this episode of Demystifying PANS/PANDAS, Dr. Sheila Kilbane joins us to connect the dots between eczema, atopic issues, histamine, and neuropsychiatric symptoms. Join us as we break down the surprising overlap between leaky skin, leaky gut, and a leaky blood-brain barrier in kids with chronic inflammatory issues and offer practical, doable ...

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From toxins to trauma, diet to infections—modern kids face more than we realize. In this episode of Demystifying PANS/PANDAS, Beth Lambert and Dr. Heather Tallman Ruhm of the Documenting Hope Project join us to talk about why children’s chronic conditions like autism are driven by a ‘total load’ of modern-life stressors. Uncover how their groundbreaking research empowers parents to identify these invisible stressors and kickstart l...

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What if the fastest way to calm the brain starts in the gut? In this episode of Demystifying PANS/PANDAS, Dr. Sabine Hazan reveals surprising links between gut microbes and the brain—showing how tiny shifts in bifidobacteria can influence cognition, behavior, and recovery. She also unpacks the truth about fecal transplant, what makes a ‘good’ donor, why environment and product quality can undo progress, and how to verify real micro...

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What if your child’s symptoms trace back to your home’s air and dust? In this episode of Demystifying PANS/PANDAS, Meredith Pleiter, an environmental health coach, joins us to reveal the eight non-negotiables for successful mold remediation. He also shares practical, budget-friendly steps families can take now to protect their kids from mold.

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What if your home is quietly keeping your child sick—even after mold remediation? Here’...

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At ReligenDX, we are revolutionizing diagnostic testing by equipping healthcare professionals with cutting-edge tools for early detection, targeted interventions, and improved patient outcomes. Our innovative solutions, including the Folate Receptor Antibody Test (FRAT) for PANS, PANDAS, and Autism, provide critical insights into neurological and immune-related conditions. With a commitment to scientific excellence and personalized...

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School closures, masking, and fear left scars. Here's how to rebuild resilience. In this episode of Demystifying PANS/PANDAS, Dr. Elizabeth Mumper joins us to unpack what COVID taught us about children’s health—what worked, what harmed, and how to do better next time. She connects school closures, masking, and fear with developmental and mental health fallout, then ties the virus to neuroinflammation, viral reactivation, mitoch...

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Before you treat, see the brain. This is why it matters. In this episode of Demystifying PANS/PANDAS, Dr. Eboni Cornish explains how brain scans can help us see and calm the brain inflammation that's messing with mood, sleep, and thinking. She details common root causes (vector-borne infections, mold/biotoxins, strep), the often-missed basics, and practical limbic system retraining tools that make treatment tolerable.

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Supporting the nervous system beats punishing behavior. Here’s how. In this episode of Demystifying PANS/PANDAS, Eileen Devine explains Brain First Parenting: a shift from behavior control to supporting a child’s brain and nervous system with empathy, accommodations, and co-regulation. She shows why parent healing and regulation are essential, why traditional behavior plans often fail kids with neuroimmune/neurobehavioral differenc...

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When sudden mood swings or rage don’t respond to treatment, infections may be the culprit. In this episode of Demystifying PANS/PANDAS, Dr. Rosalie Greenberg, a child and adolescent psychiatrist, explains how hidden infections can inflame the brain and trigger psychiatric symptoms. She shares real stories, warning signs to watch for, and a practical three-step approach: treat the infection, calm the immune system, and ease symptoms...

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Fake food, real damage—here’s how to protect your child’s gut and immune system. In this episode of Demystifying PANS/PANDAS, Dr. Michelle Perro joins us to share how ‘fake food’ and environmental toxins are disrupting our kids’ guts and immunity. We also explore practical steps you can start today—from choosing organic staples and cooking at home, to using bone broth, testing key minerals, gardening with kids, and even pushing for...

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