Accelerating Cancer Research - Hani Goodarzi of Arc Institute, UCSF, Exai Bio

Hani Goodarzi is Quantitative and Computational Biologist, Core Investigator at the Arc Institute, Associate Professor at UCSF, and co-founder of Exai Bio and Vevo Therapeutics. Episode links and chapters below.

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Episode Links:

• Arc Institute
• Goodarzi Lab
• Exai Bio
• Vevo Therapeutics
• UCSF Cancer Center
• Hani's LinkedIn
• Greg Brockman's Post
• NCI Cancer Stats

Chapters:

• (00:00) - Teaser
• (02:12) - Episode Introduction & Preview
• (07:35) - Hani’s Path Into Quantitative and Computational Biology
• (11:55) - The Emerging Promise of Foundation Models Such as Evo 2
• (15:53) - Dry Side vs. Wet Side of Biology
• (22:23) - Pivoting Into AI for Life Science From Unrelated Domains, and the Importance of Culture in Cross-Functional Teams
• (27:28) - How to Develop Multidisciplinary Teams: Brutal Honesty
• (30:07) - How Arc Institute’s Org and Funding Structure Enables Innovative Science
• (36:24) - How Tech Founders Are Pushing Biotech Innovation
• (39:07) - Hani’s Collaboration with NVIDIA and Greg Brockman of OpenAI
• (43:57) - The Science Behind Exai’s Early Cancer Detection Platform
• (52:05) - DNA Methylation to Improve Cancer-Specific Signals From Blood
• (55:25) - UCSF’s Application of This Technology for Breast Cancer Detection
• (58:34) - How Startups Help Bridge the Science “Valley of Death”
• (01:04:24) - Supporting Hani’s Work Through Scientific Contributions, Evangelism, and Applying the Scientific Method Across Disciplines

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