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February 17, 2025 27 mins
Dr. Brooke Britton joins James Jacobson to demystify the mitotic index—a critical factor in understanding your dog’s cancer diagnosis. Learn how this number, derived from a tumor biopsy, influences treatment decisions and prognosis for various types of dog cancers like mast cell tumors, soft tissue sarcomas, and melanomas. Dr. Britton shares her expertise in interpreting pathology reports and navigating the nuances of cancer care for your beloved pet. Topics Covered:  What is the mitotic index?  How pathologists calculate and report mitotic index.  When mitotic index is critical for treatment decisions.  The role of biopsies in cancer diagnosis and care.  Why tumors behave unpredictably and what that means for your dog.  Key Takeaway:  The mitotic index is just one of many factors in dog cancer care, but it can play a vital role in understanding tumor behavior and guiding treatment.  Your Voice Matters!   If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.   Related Links:  An article on mitotic index: https://www.dogcancer.com/articles/diagnosis-and-medical-procedures/mitotic-index/  Chapters:  00:00 Introduction  00:30 What is Mitotic Index?  01:30 How Mitotic Index Is Calculated   03:00 Tumor Heterogeneity   07:00 Mitotic Index and Prognosis   11:00 High vs. Low Mitotic Index   15:00 Biopsy and Treatment Decisions   19:00 Re-Biopsy Insights   21:00 Wrap-Up    Get to know Dr. Brooke Britton: https://www.dogcancer.com/people/brooke-britton-dvm-dacvim-oncology/  For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/   Learn more about your ad choices. Visit megaphone.fm/adchoices
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