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September 24, 2025 4 mins

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Professor Horace Ramon shares groundbreaking insights on how surgery for colorectal endometriosis significantly improves fertility outcomes, even for patients who've experienced multiple failed IVF attempts. His research reveals that removing endometriotic lesions throughout the pelvis gives patients a better chance at natural conception by addressing multiple fertility barriers.

• Endometriosis acts "like smoke" that impairs fertility at every level - affecting egg quality, sperm mobility, and creating inflammatory conditions
• Cleaning the pelvis through surgery gives patients additional opportunities for natural conception
• Deep dyspareunia (painful intercourse) from rectovaginal nodules often reduces sexual frequency, especially during ovulation
• Pain reduction after surgery may indirectly improve conception rates by enabling more frequent intercourse during fertile windows
• The connection between inflammation and fertility explains why removing disease improves the body's reproductive function

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Episode Transcript

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Speaker 1 (00:00):
Life moves fast and so should the answers to your
biggest questions.
Welcome to EndoBattery's QuickConnect, your direct line to
expert insights Short, powerfuland right to the point.
You send in the questions, Ibring in the experts and in just
five minutes you get theknowledge you need.
No long episodes, no extra timeneeded, and just remember

(00:20):
expert opinions shared here arefor general information and not
for personalized medical advice.
Always consult your providerfor your case-specific guidance.
Got a question?
Send it in and let's quicklyget you the answers.
I'm your host, alana, and it'stime to connect Today.

(00:42):
I am so honored to welcomeProfessor Horace Ramon, a
world-renowned surgeon andresearcher in the field of
endometriosis.
Professor Ramon has publishedsome of the most impactful
studies we have on fertilityoutcomes after surgery for deep
colorectal endometriosis.
His work has changed how wethink about the relationship
between endometriosis excisionsurgery and pregnancy rates,

(01:05):
especially for patients who havestruggled with multiple failed
IVF attempts.
Please help me in welcomingProfessor Horace Ramon.
Why do you think doing surgeryin those patients who had bowel
or colorectal surgery forendometriosis had such a
significant improvement infertility?
What would cause that?

Speaker 2 (01:24):
Well, we do not know exactly If the patient has a
bowel endometriosis togetherwith ovarian fallopian tube
endometriosis.
It is obvious that removing thebowel endometriosis, together
with restoring the fallopiantube patency and removing the
ovarian cyst, of course, itimproves the fertility Right.
You may have infertile womenwith bowel endometriosis and the

(01:50):
fallopian tubes are almostnormal and the ovaries are
involved by only superficiallesions.
In this case, after the surgery, I am almost sure that they
will be pregnant naturally and Ithink that in this case the
endometriosis impaired thepregnancy in an indirect manner,
because it had beendemonstrated that endometriosis,

(02:11):
like the smoke, may affect thefertility at every level,
beginning with the quality ofthe oocytes, with the mobility
of the sperm, with theinflammatory ambience of the
pelvis where the meeting betweenthe spermatozoa and ovocytes
occurs.
So at every level endometriosismay reduce the probability of

(02:38):
pregnancy and I think thatcleaning the pelvis we give a
supplementary chance for naturalpregnancy.

Speaker 1 (02:45):
It's a remarkable finding.
I feel like a lot of uswouldn't have put those two
together, Although I think in alot of ways it makes sense,
because the more your body isfighting against itself and has
a diseased state, it would makesense that it's harder to become
pregnant.
It's not your body's not at itsoptimal that it's harder to
become pregnant.

Speaker 2 (03:04):
It's not, your body's not at its optimal.
Then there is another factor ofinfertility, of natural
conception, which is the deepdyspareunia we do not speak
about.
We do not speak enough aboutdeep dyspareunia.
But women with big rectovaginalnodule have less sex than women
who are not painful, and theymay be painful, more painful,
during exactly the three days ofovulation.

(03:27):
At that time they reduce thefrequency of sexual intercourse.
They may be involved too in abetter, in an improvement of
natural conception rate.

Speaker 1 (03:37):
Yeah, well, and it makes sense, with the
inflammation that we experienceoftentimes during our cycle and
when we're in a flare, why thatwould be so much harder and
eradicating that disease is soimportant for that conception,
so your body can functionnormally and not have the
inflammation.
It makes a lot of sense fromthat perspective.

(03:57):
That's a wrap for this quickconnect.
I hope today's insights helpedyou move forward with more
clarity and confidence.
Do you have more questions?
Keep them coming.
Send them in and I'll bring youthe expert answers.
You can send them in by usingthe link in the top of the
description of this podcastepisode or by emailing contact

(04:18):
at endobatterycom or visitingthe endobatterycom contact page.
Until next time, keep feelingempowered through knowledge.
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