Foundation Fighting Blindness

Foundation Fighting Blindness

The Foundation Fighting Blindness is the driving force in the global development of treatments and cures for blinding diseases. To learn more, go to FightingBlindness.org.

Episodes

Eye on the Cure Podcast | Episode 87: Dr. Philip Beales

June 13, 2025 • 18 mins
June 13, 2025. Dr. Philip Beales, a co-founder of Axovia Therapeutics, talks to host Ben Shaberman about Bardet Biedl syndrome, ciliopathies, and his company's emerging gene therapy for Bardet Biedl syndrome type 1 (BBS1) which is moving toward a clinical trial.
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Eye on the Cure Podcast | Episode 86: Lenore von Krusenstiern, MD, PhD

May 23, 2025 • 31 mins
May 23, 2025. Lenore von Krusenstiern, MD, PhD, at BlueRock Therapeutics talks to host Ben Shaberman about the company's clinical trial for a photoreceptor replacement therapy for people with inherited retinal conditions such as retinitis pigmentosa and cone-rod dystrophy. The approach, which uses induced pluripotent stem cells to develop photoreceptor precursors, comes out of the lab of stem cell pioneer David Gamm, MD, PhD, Unive...
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J&J’s XLRP Gene Therapy Didn’t Meet Primary Endpoint in Phase 3 Clinical Trial

May 15, 2025 • 2 mins
Despite missing the primary endpoint, the treatment improved vision for some patients.
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ARVO 2025 Highlight: PYC Reports Encouraging Phase 1/2 Clinical Trial Results for its RNA Therapy Targeting RP (PRPF31 Mutations)

May 13, 2025 • 4 mins
The company is planning a Phase 2/3 clinical trial for therapy in late 2025.
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ARVO 2025 Highlight: Atsena’s XLRS Gene Therapy Provides Vision and Structural Improvements in Phase 1/2 Clinical Trial

May 12, 2025 • 4 mins
Part B of the trial will enroll nine adult patients as well as three pediatric patients.
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ARVO 2025 Highlight: Beacon Reports Encouraging Results for Second Eyes Dosed in Clinical Trial for XLRP Gene Therapy

May 9, 2025 • 3 mins
The company is currently enrolling patients in its Phase 2/3 VISTA Clinical Trial.
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Eye on the Cure Podcast | Episode 85: Cindy Elden

May 9, 2025 • 28 mins
Cindy Elden, who co-founded the Usher III Initiative with her late father, talks to host Ben Shaberman about her journey with Usher syndrome type 3 (USH3), the decades-long work and persistence of her non-profit, and the clinical trial it launched for an USH3 small molecule therapy.
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Eye on the Cure Podcast | Episode 84: Contact Congress

April 1, 2025 • 35 mins
April 3, 2025. In this episode of Eye on the Cure, Jen Bernstein at Horizon Government Affairs, and Sharon King of Taylor’s Tale, talk to host Ben Shaberman about how to schedule and conduct a visit with your House Member in your local district to advocate for important issues. With federal eye research funding at great risk and a Congressional district work period coming in mid-April, now is an ideal time to schedule a visit with ...
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Eye on the Cure Podcast | Episode 83: Michel Michaelides

March 19, 2025 • 33 mins
March 21, 2025. Professor Michel Michaelides, a world-renowned clinical researcher for inherited retinal diseases at Moorfields Eye Hospital and University College London, talks to host Ben Shaberman about the extraordinary vision improvements for young blind children receiving gene therapy for Leber congenital amaurosis 4 (LCA4). Professor also talks about emerging therapies in clinical trials for X-linked retinitis pigmentosa and...
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Luxa Reports Vision Improvements in Clinical Trial of its RPE Stem Cell Therapy for Dry AMD

March 10, 2025 • 4 mins
Patients with worse vision at trial enrollment had greatest vision improvements.
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Neurotech’s Encapsulated Cell Technology Receives FDA Approval for Treatment of MacTel

March 6, 2025 • 2 mins
The technology was previously funded by the Foundation for the treatment of retinitis pigmentosa and dry age-related macular degeneration.
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Eye on the Cure Podcast | Episode 82: Dr. Aaron Nagiel

March 4, 2025 • 32 mins
March 7, 2025. Aaron Nagiel, MD, PhD, a retina surgeon at Children’s Hospital Los Angeles, talks to host Ben Shaberman about how gene therapy is administered to the retina, what the surgery and recovery is like for patients, and the vision improvements for young patients receiving LUXTURNA, the first FDA-approved gene therapy for the eye or an inherited condition. Dr. Nagiel also discusses other retinal gene therapies in clinical ...
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Adverum Advancing Wet AMD Gene Therapy into Phase 3 Clinical Trials

February 27, 2025 • 3 mins
In earlier clinical trials, the emerging gene therapy greatly reduced the treatment burden associated with injections of approved anti-VEGF therapies.
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LCA4 Gene Therapy Restores Meaningful Vision for Blind Children

February 23, 2025 • 3 mins
MeiraGTx hopes to apply for marketing approval in the UK for the gene therapy.
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Eye on the Cure Podcast | Episode 81: Ricky Enger

February 19, 2025 • 49 mins
February 21, 2025. Ricky Enger, the Director of Practical Help for Hadley, talks with host Ben Shaberman about her personal and professional journeys as someone born completely blind and the many assistive and accommodative technologies that are helpful to people with low vision. At Hadley, Ricky develops technology workshops and other community initiatives for older adults new to vision loss.
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RD Fund Invests in Perceive Pharma for Development of Neuroprotective Therapies

February 17, 2025 • 2 mins
Perceive Pharma is a spin out of Perceive Biotherapeutics.
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Harriet Finkelstein, Foundation Angel, Passes Away

February 4, 2025 • 3 mins
Though unaffected by vision loss, she brought great passion to driving the Foundation’s mission.
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Eye on the Cure Podcast | Episode 80: Aniz Girach, MD

January 24, 2025 • 26 mins
January 24, 2025. Aniz Girach, MD, the chief medical officer at SpliceBio, talks to host Ben Shaberman all about the company’s emerging protein-splicing therapy for Stargardt disease which has received clearance from the FDA to move into a clinical trial.
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Atsena to Launch Part B of Phase 1/2 Clinical Trial for XLRS Gene Therapy

January 9, 2025 • 4 mins
The Foundation is a founding investor in Atsena.
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Eye on the Cure Podcast | Episode 79: Damon Lembi

January 5, 2025 • 35 mins
January 10, 2025. Damon Lembi talks to host Ben Shaberman about his journey as a college baseball star, father, and CEO of Learnit (a live learning platform), and how the diagnosis of an inherited retinal disease informs his leadership style, personal growth, and relationships. Damon is also a best-selling author and host of the Learn-It-All podcast.
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