Foundation Fighting Blindness

Foundation Fighting Blindness

The Foundation Fighting Blindness is committed to finding treatments and cures for blinding retinal diseases that affect more than 10 million people in the United States. To learn more, go to FightingBlindness.org.

Episodes

June 18, 2021 23 min
Host Ben Shaberman interviews Dr. Daniel Chung, chief medical officer at SparingVision, which is developing a gene-agnostic therapy to preserve cone vision in people with retinitis pigmentosa, Usher syndrome, and related conditions. A clinical trial launch for the emerging treatment, known as SPVN06, is planned for late 2021 or early 2022.
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Sheila Nirenberg, PhD, a professor at Cornell and founder at Bionic Sight talks with Ben Shaberman about her company's innovative optogenetic therapy which provides hope for vision restoration for people with advanced vision loss from retinal diseases. The approach has shown encouraging results in an early stage clinical trial.
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In the inaugural Eye on the Cure podcast, host Ben Shaberman explains why the retina is such a great target for therapy development and also provides some updates from the clinical trial frontlines.
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The company is planning the launch of a Phase 2/3 trial for its XLRP gene therapy
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Precise and Sensitive Outcome Measures are Essential for Getting Vision Treatments through Clinical Trials
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Gene-editing approaches are often better suited for autosomal dominant retinal diseases than gene replacement therapies
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Cellular treatment provided significant improvements in visual acuity for subpopulation of patients with better vision
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The gene-agnostic approach shows promise for people with late-stage RP and related diseases.
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February 21, 2021 13 min
Beacon Story | Ellen Gould | My Big Break by Foundation Fighting Blindness
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Beacon Story | Charlie Kramer | Cane Signals by Foundation Fighting Blindness
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Beacon Story | Tracy Minish | Five Generations by Foundation Fighting Blindness
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Beacon Story | Dr. Shannon Boye | It's Possible by Foundation Fighting Blindness
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Beacon Story | Carolyn Covington | Life After Blindness by Foundation Fighting Blindness
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