From the Spectrum: Finding Superpowers with Autism

In this episode, we explore the critical role of serotonin in shaping sensory maps within the brain, a process vital for interpreting sensory input and navigating the world. Serotonin, a neurotransmitter and neuromodulator synthesized from the aromatic amino acid tryptophan, influences brain development by fine-tuning sensory systems. It modulates neuronal growth, synaptic connections, and plasticity, which are essential for creati...

In this episode, we discuss Autism and Education. We explore some current condition within education and some personal experiences. Specifically, the school day is in complete conflict with Autism- both Criteria A and B. This is the primary factor with the challenges of Autism in Education. The classroom requires a Social Dynamic, a Speech and Language Dynamic, and Sensory-Processing Dynamic, which is 3 strikes against Autism. In a...

This episode explores the critical role of tryptophan, an aromatic amino acid, in forming tubulin—the key protein building microtubules, which act as cellular "train tracks" for structure and movement. We delve into how microtubules drive mitosis, the process of cell division essential for growth and repair, and discuss tryptophan’s unique biochemical significance, including its single codon (UGG) and contributions to DNA methylati...

In this episode, we explore Oxytocin and Vasopressin's vast roles in Human Biology. We time travel to cover the evolution of the two molecules and learn about their functions with developing and socializing. Oxytocin and Vasopressin are dynamic molecules whereby they are Peptides and Hormones. In addition, we cover previously discussed brain regions and how the molecules work alongside key Neuromodulators like Serotonin and Dopamin...

In this episode, we navigate the fascinating world of circadian rhythms and their profound impact on our health. We cover essential biology and protocols for human health, Autism or not. We will discuss how these natural cycles of light and dark regulate our biology, from hormone production to mood and cellular function, and why disruptions—particularly from artificial light—are a growing concern in modern society. Highlighting the...

For this episode, we discuss the roles and sensitivity of mitochondria with Dr. Richard Frye, MD, PhD. Dr. Frye received an MD and a PhD in Physiology and Biophysics from Georgetown University. He is board certified in Pediatrics, Neurology with special competence in Child Neurology, and as a Certified Principal Investigator. In addition, he has a Masters in Biomedical Sciences and Biostatistics from Drexel University. Dr. Frye has...

Nicole Rincon https://www.nicolerincon.com

Nicole's X https://x.com/NicoleRinconPA

Rossignol Clinic https://rossignolmedicalcenter.com

TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdf

TACA Talks: https://www.nicolerincon.com/videos

Publications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articles

Nicole Episode 1 https://www.youtube.com/watch?v=BBkdgwVfcZI

Ni...

Why doesn't the MESENCEPHALON further subdivide into larger regions of the brain?

In this episode, we will expand on the neurulation time and focus on the brain formation, spotlighting the proencephalon, mesencephalon, and rhombencephalon, which emerge around days 22–23 of embryonic life. The proencephalon (forebrain) splits into the telencephalon—think cerebral hemispheres for cognition—and the diencephalon, home to the thalamus an...

For today's episode, we go into the science of embryogenesis, focusing on neurulation—the critical process where the neural tube forms, laying the groundwork for the central, peripheral, and enteric nervous systems. We discuss how disruptions in this early developmental stage, influenced by factors like folic acid metabolism, the sonic hedgehog pathway, and genes such as PTEN (P10), could shape the autistic phenotype. From cell pro...

For today's episode, we expand on Autism and Sensory Processing. We return to the mesencephalon—a brainstem region with superior and inferior colliculi—as a critical hub for sensory integration and attention bias. We cover four scientific articles, starting with Marco et al. (2011), which uses EEGs, MEGs, and fMRIs to reveal autism’s auditory processing inconsistencies (e.g., delayed N100/M100 cortical responses), tactile hypersens...

For today's episode, we discuss Autism and sensory processing. The episode expands on the concept of the mesencephalon (midbrain), touching on the superior and inferior colliculi, key regions that help extract and integrate sensory information. The role of melanin in sensory processing is highlighted, as it aids in signal transfer and increases efficiency in sensory organs, including the eyes, ears, and skin. The episode also conne...

In this episode, we discuss the connections between autism and eye movements, starting with the underappreciated role of eyes in human biology. We emphasize the significance of the retina, which is central to both image-forming and non-image-forming functions of vision. The discussion takes a turn towards how blind individuals also leverage their eyes for biological functions beyond sight, highlighting the pervasive influence of vi...

In this episode, we discuss the intricate relationship between Autism and speech & language, emphasizing the critical role of neuroscience in understanding these dynamics. The discussion begins by highlighting how speech and language are foundational to human evolution and social interaction, yet pose unique challenges for individuals with Autism. The episode explores the brain's key regions involved in these processes, such as...

In this episode, we explore the intricate world of autism research with Jill Escher, a dedicated philanthropist, lawyer, and parent to two Autistic young adults. Jill's journey into Autism advocacy was sparked by her children's diagnoses, with no prior family history, leading her to significant roles like president of the National Council on Severe Autism and leadership at the Autism Society in the San Francisco Bay Area. Through t...

In this episode, we delve into defining the Autistic Phenotypes, emphasizing that while these traits are straightforward to identify, understanding their depth and impact requires integrating real-life data and personal experiences. We explore the characteristics of repetitive behaviors, habits, restricted interests, and a rigid adherence to schedules, which are pivotal to the Autistic Phenotypes. We will also discuss the Basal Gan...

In this episode, we explore the connections between Autism and Parkinson's, focusing particularly on the basal ganglia and its substructures, notably the substantia nigra within the midbrain. We discuss how the substantia nigra, known for its high concentration of neuromelanin, plays a critical role in these disorders. The episode examines how neuromelanin, a dark pigment, not only absorbs all frequencies of light but also has anti...

Autism just magically shows up.

In this episode, we explore neuroplasiticity in our biology for one common environmental change- Light. Please consider 1) Critical Thinking and 2) Curiosity as we travel upstream in the biological implications causing Autism. In addition, we will explore other common health conditions related to Light. These health conditions are dementia, type 1 diabetes, obesity, type 2 diabetes, cancer, and cardio...

In this episode, we explore the Basal Ganglia. The basal ganglia are a group of subcortical nuclei that play a crucial role in orchestrating movement. They are involved in what's known as the 'Go, No-Go' decision-making process, where they help decide whether to initiate or suppress actions. This region is critical where motivation translates into action.

When discussing "motivations," we must be cautious; motivations aren't conscio...

The biology that gives us Autism allows us to be comfortable within ourselves.

Our biology orients the Autistic towards our internal state. This is more comfortable for the Autistic in comparison to the outside world. In this episode, we cover brain regions, networks, and internal calculators. All humans use these biological calculators. However, based on the living organisms unique structure of brain regions and networks (connectio...