REPLAY: Melatonin: mechanisms of action & it’s amazing role beyond sleep with Dr Adrian Lopresti and Deanna Minich

Dr Deanna Minich provides a comprehensive exploration of the diverse aspects of melatonin, offering a deeper understanding of the mechanisms and benefits of this sleep-associated neurotransmitter. The discussion, hosted by fx Medicine by BioCeuticals Ambassador Dr Adrian Lopresti, covers the different types of melatonin in the body, shedding light on its production sites and widespread presence across body systems. The episode also explores the connection between melatonin and the gut, its impact on mitochondria, and provides a detailed breakdown of the six pivotal roles that melatonin plays. The conversation touches on a variety of health conditions that melatonin may support, and outlines natural ways to enhance melatonin production—starting with optimising light exposure, dietary strategies, and the potential of plant-sourced melatonin. Listeners will also gain insights into how endogenous melatonin levels vary across life stages. Importantly, the podcast addresses safety considerations, differences in regulatory status, and offers evidence-based dosage recommendations. COVERED IN THIS EPISODE (00:58) Welcoming Dr Deanna Minich (01:53) What is melatonin? (04:27) The role of melatonin in the gut (06:31) The role of melatonin in energy production (08:27) Therapeutic benefits of melatonin (10:22) Melatonin’s role in ageing (11:43) Melatonin in inflammation (13:56) How light affects the production of melatonin (21:14) How diet affects the production of melatonin (29:21) Plant melatonin (31:39) Melatonin production reduction through ageing (34:34) Melatonin and the circadian rhythm (40:57) Melatonin - a molecule of consciousness (44:12) The role of stress in melatonin production (46:27) Melatonin supplementation (51:59) Melatonin dosage (55:48) Timing on supplementation for sleep (58:58) Synergystic effects of melatonin and nutritionals (01:00:49) Melatonin dosage in perimenopause (01:03:10) Thanking Dr. Minich and closing remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/melatonin-mechanisms-of-action-it-s-amazing-role-beyond-sleep-with-dr-adrian-lopresti-dr-deanna-minich Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://login.bioceuticals.com.au ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***