All Episodes

Dr Austin Perlmutter, neurobiology, mood and decision-making expert, joins our ambassador Dr Adrian Lopresti as they explore the biological basis of “stuckness” in the mind and how the brain is influenced by inflammatory/immune triggers which results is certain behaviours and health outcomes. Together they discuss the relationship between sickness behaviour, neuroinflammation and their effect on the brain leading to our inherent tendency to return to “default”. Nature vs nurture is discussed where exposures from foetal development, childhood trauma and genetic influences can impact our mental and cognitive flexibility much later in life. Austin explains “disconnection syndrome” a modern conundrum where our brains tend to latch onto impulsive behaviours leading to cognitive decline. It’s not all doom and gloom as Austin and Adrian bring practical solutions to the table in the form of simple lifestyle adjustments that promotes behavioural change and reduce neuroinflammation. COVERED IN THIS EPISODE (00:55) Welcoming Dr Austin Perlmutter (01:42) Preventing chronic disease and reduced brain function (05:32) Sickness behaviour and the impacts of inflammation on the brain (08:48) How genetics and environment predispose us to increased risk of brain conditions (12:46) Does early life trauma increase our risk of developing mental health conditions? (15:28) The disconnection syndrome (18:57) Chronic stress induces brain atrophy (24:02) How inflammation impacts immunity (29:00) Connections between inflammation, impulsivity and decision making (35:07) Effects of inflammation on sleep and neuroplasticity (41:05) Food for brain health (48:34) Supplementation to improve brain function and reduce inflammation (51:24) Implementing lifestyle changes and resources for practitioners (56:00) Thanking Austin and final remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/neuroinflammation-impacts-on-immunity-behaviour-brain-function-with-dr-adrian-lopresti-dr-austin-perlmutter Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://login.bioceuticals.com.au ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***
Mark as Played

Advertise With Us

Popular Podcasts

NFL Daily with Gregg Rosenthal

NFL Daily with Gregg Rosenthal

Gregg Rosenthal and a rotating crew of elite NFL Media co-hosts, including Patrick Claybon, Colleen Wolfe, Steve Wyche, Nick Shook and Jourdan Rodrigue of The Athletic get you caught up daily on all the NFL news and analysis you need to be smarter and funnier than your friends.

On Purpose with Jay Shetty

On Purpose with Jay Shetty

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.