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September 29, 2025 30 mins

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In this episode, we explore pediatric sepsis, a leading cause of critical illness and mortality in children worldwide. We discuss what sepsis is—the body’s overwhelming and life-threatening response to infection—and why children are uniquely vulnerable. The conversation highlights early recognition, focusing on key warning signs such as fever, tachycardia, tachypnea, and altered mental status.

We emphasize the importance of timely intervention: rapid antibiotics, fluid resuscitation, and escalation of care in the pediatric intensive care unit when necessary. The episode also covers evolving guidelines, best practices in sepsis bundles, and the role of teamwork in improving outcomes.

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References:

Kline-Tilford, A. M., & Haut, C. (2020). Cases in pediatric acute care: Strengthening clinical decision making. Wiley-Blackwell.

Additional Resources:

PICU Essentials on the App Store (apple.com)

PICU Essentials - Apps on Google Play

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