If you’ve ever wondered, “What if they change their mind?”—you’re not alone. This episode breaks down the newest data on how often trans youth stop hormone therapy and retransition to a cisgender identity.
We walk through a 2025 study of over 1,000 adolescents and explore what it really tells us—about numbers, nuance, and how we think about gender-affirming care.
📚 Citation:
Boskey ER, Scheffey KL, Pilcher S, et al. A Retrospective Cohort Study of Transgender Adolescents' Gender-Affirming Hormone Discontinuation. J Adolesc Health. 2025;76(4):584–591. doi:10.1016/j.jadohealth.2024.11.002
Olson KR, Durwood L, Horton R, Gallagher NM, Devor A. Gender Identity 5 Years After Social Transition. Pediatrics. 2022;150(2):e2021056082. doi:10.1542/peds.2021-056082
van der Loos MATC, Hannema SE, Klink DT, den Heijer M, Wiepjes CM. Continuation of gender-affirming hormones in transgender people starting puberty suppression in adolescence: a cohort study in the Netherlands. Lancet Child Adolesc Health. 2022;6(12):869-875. doi:10.1016/S2352-4642(22)00254-1
Roberts CM, Klein DA, Adirim TA, Schvey NA, Hisle-Gorman E. Continuation of Gender-affirming Hormones Among Transgender Adolescents and Adults. J Clin Endocrinol Metab. 2022;107(9):e3937-e3943. doi:10.1210/clinem/dgac251
Gupta P, Patterson BC, Chu L, et al. Adherence to Gender Affirming Hormone Therapy in Transgender Adolescents and Adults: A Retrospective Cohort Study. J Clin Endocrinol Metab. 2023;108(11):e1236-e1244. doi:10.1210/clinem/dgad306
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