April 8, 2025 • 37 mins
In this episode, Dr. Alfred Alessi delves into the intricate world of aging and anti-aging, distinguishing between biological and chronological age and identifying key drivers of aging. He presents comprehensive anti-aging strategies and cutting-edge methods, highlighting the five biggest causes of aging. The discussion covers various tools, supplements, and biohacks, including advanced tech like cold and red light therapy, intermittent fasting, autophagy, and hyperbaric oxygen therapy. Dr. Alessi shares insights on biohacking, peptides, and the role of stem cells in anti-aging, introducing Softwave Therapy as part of an ultimate anti-aging blueprint. The episode concludes with guidance on personalized anti-aging plans and staying connected.
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Episode Transcript
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(00:00):
Aging isn't just about getting older.
(00:02):
It's a biological process driven by specificcellular mechanisms.
While conventional wisdom says aging isinevitable, modern science has debunked that
and identified key drivers that speed it up,but more importantly, slow it down.
So let's break down the five biggest causes ofaging and what we can do about them.
Welcome to Health Decoded, your number onesource for real health information with your
(00:24):
host, Doctor.
Alessi and Matt Tack.
Alright.
Welcome back to another episode of HealthDecoded.
I am your host, doctor Alfred Alessi.
And today, we are going to talk about a reallycool topic and something that's very popular in
today's culture, especially with the prevalenceof so many chronic diseases on the rise.
(00:48):
We're gonna talk about anti aging and how wecan reverse cellular aging without having to
break the bank on expensive treatments.
And so, aging isn't really just about gettingolder, it's actually about how fast your cells
are breaking down.
So most people think of aging as an inevitableprocess.
They count the number of their birthdays,right?
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And it's just a number that increases everyyear.
But what if I told you that the number ofcandles on your birthday cake doesn't actually
determine how old you are at the biologicallevel?
Aging isn't just about time passing, it's aboutthe rate of cellular breakdown inside your
body.
Some people in their 60s are still runningmarathons and thriving, while others in their
40s feel exhausted and have chronic joint pain.
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And so what is the difference?
It's their biological age.
So your chronological age is simple it's howmany years you've been alive, but your
biological age, it's much more important.
It measures how well or how poorly your cellsorgans and tissues are functioning compared to
others of the same chronological age.
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For example, a 50 year old with greatmitochondrial function, strong telomeres and
low inflammation could have a biological age of35.
Meanwhile, a 40 year old with high oxidativestress, insulin resistance and chronic
inflammation could have a biological age of 60.
And so what is the difference?
It's your cellular health.
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So what drives biological aging?
Here's a few things.
Mitochondrial decline.
Mitochondria are the powerhouses of our cells.
So, this causes our cells to lose energyproduction, which can lead to fatigue and
disease over time.
Another one is telomere shortening.
So, the telomeres are the caps at the end ofyour DNA, and over time they can wear down,
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which can lead to cellular dysfunction.
Chronic inflammation, which we have talkedabout in previous episodes is the silent killer
behind heart disease, dementia and cancer.
Things like glycation and insulin resistance.
So, basically sugar accumulating in the bloodover time can cause damage to proteins and
accelerate aging.
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And then, probably one of the biggest ones isoxidative stress.
Oxidative stress is when things called freeradicals in the blood and in the cells can
attack your cells and cause premature aging.
And so there's a study in the Journal ofGerontology in 2021 found that people with
better mitochondrial function and lowerinflammation actually had biological ages up to
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fifteen years younger than their chronologicalage.
And so, aging isn't about the calendar, it'sabout how fast your body is breaking down at
that cellular level.
And now what's the best part to this?
We can slow that down or reverse it.
And so what if you could slow, stop or evenreverse aging at the cellular level?
For decades, scientists believe aging was justinevitable.
(03:41):
But recent breakthroughs in longevity researchsuggest we can actually reverse many aspects of
aging.
Can we slow aging?
Absolutely.
Lifestyle, diet, and certain biohacks canactually dramatically reduce the rate of
cellular breakdown.
Now, can we stop aging?
Not completely, but we can delay major agingmarkers by decades.
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How can we reverse aging?
In some cases we can by restoring mitochondrialfunction, clearing out what are called
senescent or zombie cells, and regeneratingtissues with stem cells or peptides.
A study in the journal Nature twenty twentyfound that hyperbaric oxygen therapy increased
telomere length by 20%, effectively reversingkey markers of aging.
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So the future of aging is here.
Scientists are now exploring cutting edge waysto slow and reverse aging, including things
like NAD boosters to fuel the mitochondria,Things like senolytics which clear out old
damaged cells.
This is also doable with fasting.
Peptides and stem cells that regenerate tissuesthat have been damaged.
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And then fasting and autophagy to triggercellular repair.
So aging just isn't something you have toaccept with the right strategies, you can take
control of your biological age, reverse it andslow the clock.
And so in this episode, I'm gonna break downwhat the science of anti aging is, not gimmicks
or expensive treatments, but cutting edgeresearch back ways to slow and even reverse
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cellular aging.
So, the root causes of aging, how to stop them,the most powerful anti aging supplements that
actually work that have been studied andproven, Biohacks like red light therapy,
fasting, cold exposure, and then peptides, stemcells and regenerative medicine, how they work
and who should use them.
So, by the end of this episode, you'll walkaway with an action plan to not only live
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longer, but to live stronger, healthier, andsharper for decades to come.
So let's dive in.
So like I discussed aging isn't just aboutgetting older.
It's a biological process driven by specificcellular mechanisms.
While conventional wisdom says aging isinevitable, modern science has debunked that
and identified key drivers that speed it up,but more importantly, slow it down.
(06:01):
So, let's break down the five biggest causes ofaging and what we can do about them.
So number one, mitochondrial dysfunction.
So this is basically the energy crisis ofaging.
Your mitochondria are like power plants in yourcells.
They produce energy, which is called ATP thatfuels everything from brain function to muscle
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movement.
And as we age, the mitochondria become lessefficient, producing less energy and more
oxidative stress, which is a byproduct of thoseprocesses with inside.
This can lead to things like fatigue, cognitivedecline, and then even chronic disease.
So, does this happen?
Because the damaged mitochondria produce excessfree radicals, which cause damage
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intracellularly.
Declining NAD plus levels can reducemitochondrial function because NAD is a
critical co enzyme that declines with age, andit was responsible for that production of ATP.
Things like toxins and poor diet can thenaccelerate mitochondrial breakdown.
So a study in the journal Nature 2020 foundthat mitochondrial decline is one of the
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biggest drivers of aging and chronic disease,impacting everything from heart health to
neurodegeneration.
And so what is a solution for this boostingmitochondrial function with NAD plus precursors
things like NMN, NR, CoQ10, and specificallyexercise like HIIT training and strength
training.
We're going to get a little bit more into thisin the segment when we talk about solutions.
(07:32):
So what's number two on our list, telomereshortening.
So this is basically like a biological timebomb telomeres are the protective caps at the
end of your DNA strands, kind of like theplastic tips on the end of shoelaces.
Each time your cells divide, the telomeres getshorter until eventually they become too short
to function which can lead to cellulardysfunction and aging.
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So, why does this happen?
Chronic stress and inflammation can acceleratetelomere loss.
Poor lifestyle choices, things like smoking,processed foods, sedentary life, they speed up
that shortening as well.
Oxidative stress damages DNA which leads to thepremature aging.
A study in The Lancet 2017 found that peoplewith longer telomeres had a significantly lower
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risk of heart disease, dementia, and earlymortality.
So, what's the solution for this one?
Activating telomerase, which is the enzyme thatrepairs telomeres.
We can do this a few different ways things likefasting, meditation and mindfulness and
specific nutrients.
We'll get more into that third on the listchronic inflammation and oxidative stress.
(08:40):
We did an episode on this a few weeks backabout how these are the silent killers, and
basically responsible for a majority of chronicdisease.
Inflammation is a normal immune response, butchronic inflammation can wreak havoc on the
body.
It's linked to heart disease, diabetes, cancerand neurodegeneration.
So what spurs chronic inflammation things likea poor diet, high and processed sugars and
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foods seed oils, chronic stress that triggersexcess cortisol and environmental toxins, like
pollution, heavy metals, which can acceleratethat oxidative damage.
A study in the Journal of Gerontology twentytwenty one found that people with lower
inflammation had biological ages up to fifteenyears younger.
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So, what's an approach here is to follow ananti inflammatory diet.
Rich in Omega-3s, polyphenols and antioxidants.
Practicing intermittent fasting, giving yourgut a break, allowing it to lower that
inflammation, and using red light therapy tocombat inflammation as well.
Number four, cellular senescence.
The buildup of zombie cells.
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So, as we age, our bodies accumulate senescentcells.
These are cells that are no longer functioningproperly but refuse to die.
So instead they linger in the body, secretingharmful compounds that can damage surrounding
tissues and accelerate aging.
So why does this happen?
Because these damaged cells fail to selfdestruct, which is called apoptosis.
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It's a natural cellular process.
These senescent cells release things likeinflammatory chemicals, which can speed up the
aging and contribute to that process wediscussed.
And declining immune function allows thesezombie cells to accumulate.
So, a study done in Aging Cell Journal 2018found that clearing out senescent cells with
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senolytic compounds, things like quercetin andfisetin, reversed biological aging markers in
mice and humans.
So what's the solution?
Using senolytics, things like we just saidquercetin, fisetin, resveratrol, and
intermittent fasting to promote a processcalled autophagy, which is your body's natural
cleanup process.
Number five, epigenetic changes.
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Basically, the on off switch for aging genes.
So, your epigenome controls which genes getturned on or off based on lifestyle factors.
Where we have internal genetic predispositiondispositions based on our family history, the
DNA of our parents and those things.
Epigenetics is what our lifestyle and externalenvironment can contribute to our DNA.
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So, is things like diet, exercise, stress.
As we age, harmful genes can get activatedwhile protective genes get suppressed, leading
to disease and dysfunction.
So, now why does this happen?
Toxins and poor diet trigger harmful geneexpression.
Chronic stress and poor sleep actually turn onthese genes that accelerate aging.
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And lack of movement, sedentary lifestylesuppresses genes that will promote longevity.
A study done in the journal Cell twentynineteen found that lifestyle interventions
such as exercise, fasting and stress managementcould reverse these epigenetic markers of
aging.
So what's a key takeaway here for everything wejust discussed is that aging isn't inevitable.
(11:59):
It's a process that you can slow down, right?
And so, the latest research confirms that agingis not just wear and tear, it's driven by
specific cellular mechanisms, most that wedon't even know are happening, but that we can
influence with specific measures.
So, what does this mean for you?
Mitochondria can be strengthened with the rightnutrients and exercise.
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Telomeres can be protected with stressreduction, things like Omega-three's.
Inflammation can be controlled with dietfasting biohacks.
Senescent cells can be cleared out withsenolytics and autophagy and your genes can
ultimately be reprogrammed for longevity withspecific lifestyle changes.
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So, what's the bottom line?
Aging is no longer a mystery.
We know what causes it, but more importantly,we know how to slow it down.
And so, in this next segment, we're going todive into the most powerful tools, supplements
and even biohacks to reverse biological agingand keep your body and mind strong for decades
to come.
But first, here's a quick word from one of oursponsors.
(13:03):
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Now back to the episode.
Alright.
Welcome back.
So if you wanna slow down aging, extend yourhealth span and keep your body functioning at
peak performance, certain nutrients andsupplements have been scientifically proven to
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directly impact the aging process at thecellular level.
These compounds go beyond basic healthmaintenance, they actually repair your DNA and
optimize that mitochondrial function.
Doing things like reducing inflammation andmaking them essential tools in any anti aging
protocol.
So let's get into it.
Let's break down some of the most powerfulscience backed anti aging nutrients, and why
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and how they work.
So number one on my list here is things likeNAD plus boosters.
These are NMN and NR, also known asnicotinamide mononucleotide or nicotinamide
riboside.
These are the ultimate cellular fuel.
So, NAD plus is one of the most criticalmolecules for longevity.
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It's responsible for cellular energyproduction, DNA repair, and mitochondrial
health.
Unfortunately, NAD plus levels decline by 50%by middle age, leading to fatigue, cognitive
decline, and increased disease risk.
So, how it works.
NAD plus powers your mitochondria, which isyour body's power plant.
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It activates DNA repair enzymes to preventcellular damage and enhances the activity of
things called sirtuins, which are proteins inthe body that extend lifespan and protect
against age related decline.
So, a study in the journal Cell Metabolism in2018 found that NMN supplementation reversed
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age related vascular decline, restoring bloodflow and energy production to youthful levels.
So, are some of the best sources for NAD plusNMN, which is nicotinamide mononucleotide, and
NR, which is nicotinamide riboside.
These are the two best ways to boost NAD plusNext on my list here, Resveratrol and
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Terrostilbene, the longevity gene activators.
So, Resveratrol is a more potent cousin andpterostilbene are powerful polyphenols that
activate sirtuins.
The same longevity genes stimulated by fastingand calorie restriction.
So how does it work?
Basically, it mimics the benefits of fastingwithout caloric restriction.
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It's going to reduce oxidative stress thataccelerates cellular aging, and it's going to
protect the brain and heart by reducinginflammation.
So, a study out of Harvard University byDoctor.
David Sinclair showed that resveratrol mimicsthe benefits of fasting, activating sirtuins
and extending lifespan.
Some of the best sources for these are thingslike red grapes, blueberries, dark chocolate,
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or supplementation for a higher dose effect.
Next on my list here, I have CoQ10 and PQQ, themitochondrial superchargers.
So, you want more energy, better endurance,improved brain function, Coenzyme Q10 and
Pyrroloquinoline quinine are essential.
These compounds enhance mitochondrial function,helping your bot your cells to produce ATP and
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obviously energy more efficiently.
So, basically Co Q ten fuels mitochondrialproduction, while PQQ will stimulate the growth
of new mitochondria.
So, basically, it's a process calledmitochondrial biogenesis.
So, basically, these two in combination aregoing to enhance the way that your
mitochondrial grow and function, and protectthese cells from damage.
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So a study in the Journal of ClinicalInvestigation 2015 found that CoQ10 improved
heart function and reduced fatigue in agingindividuals.
Some of the best sources for these are grassfed meat, fatty fish, certain nuts, or high
quality supplementation.
Next on my list here, and this was discussedheavily in the last two episodes, magnesium and
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vitamin D three with K two.
These are anti inflammatory essentials.
Magnesium and D three K two work together tooptimize cellular function, improve bone
health, heart health, and regulateinflammation.
So, magnesium is the master co enzyme.
It's basically needed for over 300 enzymaticprocesses, including DNA repair and energy
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production.
Whereas vitamin D3 paired with K2 work togetherto direct calcium where it belongs into the
bones, not into the arteries.
Both of these are going to reduce chronicinflammation, and then slow down those aging
related diseases.
A study out of the European Journal ofNutrition 2019 found that vitamin K two
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supplementation reduced arterial stiffness byfifty percent, lowering heart disease risk.
So, some of the best sources, magnesium, youcan get from dark leafy greens, nuts, avocados,
vitamin D three and K two, obviously sunlight,certain fermented foods or you can always
supplement.
And so number five on this list is Omegathree's including EPA and DHA.
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So, these are what we consider like a cellularshield.
The Omega three fatty acids are going tosupport brain health, reduce inflammation and
protect against cellular damage.
They are essential because the body cannotproduce them on its own.
So basically EPA fights inflammation,protecting cells from this oxidative stress,
and then DHA is going to support brainfunction, preventing against things like
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neurodegeneration.
Both of these are going to enhancecardiovascular health, reducing the risk of
heart disease.
So I always recommend you get a good omegathree supplement that has a combination of EPA
and DHA.
So a study out of the American Journal ofClinical Nutrition in 2016 found that
increasing omega three intake reduced heartdisease risk by thirty percent.
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Some of the best sources are going to be wildcaught fish like salmon and sardines, grass fed
beef, walnuts, or high quality fish oilsupplements.
So what's a key takeaway here is that thesenutrients don't just support health, they
actively reverse the aging process.
So, for you, what this means is you can boostNAD plus levels to restore cellular energy.
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You can activate your longevity genes withresveratrol and fasting, supercharge
mitochondria with CoQ10, PQQ and magnesium.
Protect your arteries and brain health withvitamin D3, K2 and Omega 3s, and ultimately
slow inflammation and oxidative stress toextend your lifespan.
So the right supplements aren't just going tohelp you feel better, they're going work at the
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cellular level to slow, stop, and even reverseaging.
So if you ever want to learn more about what wecall smart supplementation, and how to know
what's right for you, go to a lessee functionalhealth doc, book a consultation with me or one
of my amazing doctors, and learn how functionalmedicine can help you.
Now we're going to explore some of the morecutting edge advanced anti aging technology and
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biohacks, from stem cells to peptides and more.
So if you're serious about slowing, stoppingand even reversing aging, advanced biohacks can
supercharge your results.
These aren't just gimmicks, these arescientifically backed interventions.
They're going to work with your body's naturalbiology to enhance your mitochondrial function,
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regenerate tissues, lengthen your lifespan.
So, let's get into some of the more powerfulanti aging biohacks and the science behind
them.
Number one, you've probably all heard of thiscold therapy.
Cryotherapy, ice baths, cold showers.
Basically, these are the ultimate longevityreset.
Cold exposure activates something called brownfat, which boosts your metabolism, reducing
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inflammation and stimulating the release oflongevity proteins like adiponectin.
It's also a powerful hormetic stressor.
Hormetic meaning a short controlled shock toyour system that triggers stronger cellular
repair mechanisms on the back end.
So how does it work?
When you get into the cold it activates whatare called cold shock proteins that are going
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to enhance cellular resilience.
It's going to increase mitochondrialefficiency, leading to better energy
production, and it's going to reduceinflammation and oxidative stress.
So, a study out of the European Journal ofApplied Physiology in 2017 found that regular
cold exposure significantly increasedantioxidant defenses, helping cells fight
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aging.
So how to do it?
Okay, take a thirty to sixty second cold showerafter a workout or in the morning when you
shower.
The best way to get into this is to start withwhat we call a cold finish.
You just took your shower, you're ready to go,thirty to sixty seconds of cold right at the
end.
To take it to the next level, you can trycryotherapy or ice baths, where you're going to
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get your whole body emerged into cold, up tothree to five minutes at a time.
So now number two on this list, red lighttherapy using the process of
photobiomodulation.
This is going to reverse aging at the cellularlevel.
So red and near infrared light stimulatemitochondria to produce more ATP, helping cells
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to repair damage, inflammation and enhancefunction.
So how does it work?
It's going to boost the mitochondrial function,increasing energy production at the cellular
level, enhancing collagen production, reducingwrinkles and skin aging.
That's awesome.
And it's going to improve cognitive function byincreasing blood flow to the brain.
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So a study out of the Frontiers in AgingNeuroscience twenty twenty found that red light
therapy reversed age related cognitive declineand improved memory in older adults.
So how do we use it?
You can invest in a high quality red lighttherapy device, something like a Juve or a
MitoRed.
You can use that for ten to twenty minutes perday on the face, joints or the muscles for
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cellular regeneration.
Or infrared sauna for full body mitochondrialactivation.
Highly, highly recommend infrared sauna.
Number three, very very powerful mechanism hereis intermittent fasting, or fasting mimicking
diets.
These are going to trigger the process ofcellular autophagy and regeneration.
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So fasting isn't just for weight loss, itactivates autophagy, which is your body's built
in cellular cleanup process.
During fasting damaged proteins anddysfunctional cells are broken down, recycled,
leading to stronger healthier cells.
So how does it work?
Fasting triggers this autophagy process whichhelps the body to remove damaged cells.
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The analogy I like to use is think of a busypost office.
If they're constantly getting new mail in, it'shard for them to process the mail that they
already have in the office to then get thatout.
So, you can take the break from putting foodinto the gut and into the body, it now has the
ability to take that damaged and old tissue,get that out, and regenerate what's needed.
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Fasting is also going to lower insulinresistance, reducing the risk of metabolic
disease.
So a study in stem cell 2014 found that fastingfor seventy two hours could regenerate the
entire immune system, increasing stem cellactivity.
So how to do it.
Okay, and you have to be careful here if you'venever done it you want to start light.
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So starting with what we consider a sixteeneight intermittent fasting.
So you're going to fast for about sixteenhours, and then you're going to schedule your
eating within an eight hour window.
Then once you've gotten good at that and youfound some balance your body can tolerate it,
then I would recommend you try going for moreof a twenty four to forty eight hour fast once
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or twice a month for that deeper cellularcleanup.
Also experience experimenting with fastingmimicking diets for benefits without full
fasting.
We partner with a brand called Prolon where wecan use these specific formulas to still get
calories and nutrition in, but it mimics theconcept of fasting and allows the body to get
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the benefits.
Next on the list here, and this is a little bitmore high-tech is hyperbaric oxygen therapy.
This is going to lengthen telomeres and reverseaging.
So hyperbaric oxygen therapy increases oxygenlevels in the tissues promoting cellular repair
and lengthening telomeres.
It enhances oxygen delivery, improves cellularrepair, boosts collagen production, which can
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improve skin, joints and connective tissue, andit can increase stem cell production as well.
So, how to do it?
Okay, medical grade HBOT chambers, you would dofor about sixty-ninety minutes per session for
a deep rejuvenation.
You can use the soft HBOT chambers which arelower pressure at home.
Obviously these devices are not cheap.
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There are places where you can go and do theseon a regular basis, two, three, four days a
month.
You can combine the HBOT with fasting for amore powerful synergy in this anti aging kick.
So, what's a key takeaway here?
Biohacking can unlock a lot of your body'snatural anti aging powers that have been
suppressed.
So, does this mean?
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Cold therapy builds resilience, fightsinflammation.
Red light therapy supercharges themitochondria, reverses cognitive decline.
Fasting will trigger cellular cleanup andregenerate stem cells.
And hyperbaric oxygen can lengthen telomeresand reverse aging at the DNA level.
So what's the bottom line?
You don't need expensive unproven anti agingtreatments, because these cutting edge biohacks
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work with your biology to extend lifespan andhealth span naturally.
So now, we're going to explore some moreadvanced regenerative therapies like peptides,
stem cells and gene therapy that are changingthe future of longevity.
So here we go.
Alright, so let's get into the role of peptidesand stem cells in anti aging.
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So we've covered some natural strategies, somecutting edge biohacks, and now let's dive into
the next frontier of longevity.
Things that are really exciting, and that we'reexperimenting with at Alessi functional health
as well peptides and stem cells.
So these are powerful tools, and they have thepotential to regenerate tissue, enhance your
cellular repair, and extend your lifespan.
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So, it's not just hype anymore, scientificstudies are proving that these therapies can
actively slow and reverse biological aging.
So peptides, which are basically the nextfrontier in longevity, what they are, they're
short chains of amino acids that act assignaling molecules in the body.
Unlike traditional pharmaceuticals, peptideswork with your body's natural processes to
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enhance repair, recovery and longevity.
A peptide in particular, Epitalin, is known forextending lifespan at the genetic level.
What it does is a peptide that activatestelomerase, which is the enzyme responsible for
maintaining and lengthening your telomeres.
Longer telomeres are linked to increasedlifespan and reduced aging related disease.
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A study out of the International Journal ofMolecular Science in 2019 found that Epitalin
increased longevity in animal models bypromoting telomerase activity.
So what it's going do is it's going to extendlifespan by maintaining the telomere length,
improve your sleep quality and circadianrhythm, and boost your immune function.
The next peptide, one that I've used a ton andrecommend to a lot of patients who come in with
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joint pain and overall body pain is BPC-one 57.
This is the tissue regeneration peptide.
So, BPC-one 57 is a healing and recoverypowerhouse.
Originally discovered in the stomach, it's beenshown to rapidly regenerate tissues.
It can also heal the gut lining and reduceinflammation throughout the body.
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Another reason we use it is for things likeleaky gut, or celiac disease.
So, the benefits are going to be that it'sgoing to heal muscle, ligament and tendon
injuries.
It's going to repair gut damage from conditionslike leaky gut and IBS, and it's going to
reduce overall inflammation and oxidativestress.
So then the next ones that are fantasticthymosin alpha one and thymosin beta four,
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which are the ultimate immune and recoveryboosters.
You pair these with BPC one hundred fifty sevenand they basically double down on the effects.
So, these peptides are critical for immunefunction, wound healing, cellular repair.
Thymosin Alpha one enhances the immune systemstrength, helping the body fight infections and
slow aging.
Thymosin Beta four speeds up tissue repair,improving brain function, reducing
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inflammation, all linked to aging.
So, who can benefit from this?
Those recovering from injury or surgery,individuals with weakened immune systems, or
those looking to reduce inflammation and slowaging.
So now let's talk a little bit about stem celltherapy and regenerative medicine.
Stem cells are awesome.
They're your body's raw materials forregeneration.
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They have the ability to develop into any typeof cell and repair damaged tissue.
But as we age, our natural stem cell productiondeclines, leading to slower healing and
increased degeneration.
So mesenchymal stem cells or MSCs repair agingtissue.
They are powerful anti inflammatory andregenerative agents.
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They're going to reduce those senescentmarkers, which is the damaged and aging cells.
They're going to go in and repair joints,muscles, nerves, and they're also going to
enhance skin and tissue regeneration.
So a study in the Journal of TranslationalMedicine 2018 found that mesenchymal stem cell
therapy rejuvenates aging tissue by reducingsenescent markers and promoting tissue repair.
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So how do we use these, right?
In our clinic, we use them for jointregeneration, for things like arthritis and
cartilage repair, overuse injuries, forneurological conditions such as Parkinson's,
Alzheimer's, stroke recovery, and for whatwe're talking about today, the anti aging skin
and kind of cosmetic procedures as well.
Another way that we can activate stem cells isthrough something called softwave therapy.
(32:30):
So in our clinic at Alessi Functional Health,we have a device called a softwave therapy
unit.
This activates your body's own stem cells.
So rather than an injection, the soft wavetherapy is a non invasive regenerative
treatment that activates dormant stem cellswithin your body.
It's going to kick start healing and tissuerepair without surgery, drugs or injections.
(32:53):
So, how does it work?
It uses acoustic wave technology to stimulate amechanism within the body to promote tissue
repair.
This is going to activate dormant stem cells togo to the area.
It's also going to reduce inflammation andaccelerate recovery while lowering pain.
So, Softwave is really the future ofregenerative medicine without the high cost and
(33:14):
risk of stem cell injections.
Now when we pair the two together, we canenhance the results tenfold.
So, of the key takeaways here is that peptidesand stem cells are really the future for
longevity, anti aging and regenerativetherapies.
So peptides like Epitalin, BPC-one 57 andThymosin can actively reverse aging and enhance
(33:37):
recovery.
Stem cell therapy is gonna repair aging tissueand reduce inflammation, and soft wave therapy
is gonna stimulate your body's naturalregenerative powers without the injections.
Now, you use all three of these thingstogether, you are going to be an anti aging
recovering powerhouse.
And so we're no longer just managing aging,we're actually reversing aging at the cellular
(33:59):
level.
And so, as we wrap up here, I really want toleave you guys with some action and some things
that you can start today to kind of startslowing that aging process naturally and taking
more initiative.
So, this is what I'm going to call yourultimate anti aging blueprint.
Okay?
So, start incorporating some daily habits, suchas cold exposure, strength training, optimizing
(34:23):
your sleep.
Get some key supplements, things like NADboosters, Resveratrol and Omega-3s.
And then, look into some of the more advancedtherapies like red light therapy, fasting,
regenerative medicine.
And so at Alessi Functional Health, ourapproach is with functional medicine.
So with functional medicine, we create apersonalized protocol which combines the
(34:46):
cutting edge therapies like soft wave and stemcells, as well as the natural holistic methods
to activate your body's natural healingmechanisms and reverse aging from the cellular
level.
So, in conclusion, the future of aging is notjust about living longer, it's about living
better, stronger and sharper.
So, aging is optional.
(35:08):
And so, if you're curious about creating apersonalized plan for lifelong cellular health
and longevity, schedule a consultation.
Go to a lesseefunctionalhealth You can book aconsultation right on the website, sign up for
our newsletter, check out our resources page,learn more about our approach, and how we use
these cutting edge therapies.
(35:30):
Listeners of the Health Decoded podcast aregoing to get exclusive discounts and price
reductions on all supplements, blood work, andeven therapies.
So as always, if you found value in today'sshow, please like and smash that subscribe
button.
Share this episode with someone who needs tohear it.
That's the only way we get the word out is ifyou share and you spread the word.
(35:51):
And if you wanna get in touch with us or evenbe featured on an episode, email us, send us
questions to ask at Alessi FX Health dot com.
We might answer those live on the show.
As always, thank you for tuning in to HealthDecoded, where we break down the science, bust
the myths, and help you take control of yourhealth naturally.
(36:11):
Until next time, stay curious, stay empowered,and remember, your health is in your hands.
Thank you for tuning in to Health Decoded,where we break down the truth about all things
health and empower you to take charge of yourwell-being.
If you found value in today's episode, pleasesubscribe, leave a review, and share it with
someone who needs to hear this.
(36:33):
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To hear your questions answered live on theshow, send them to askalessifxhealth dot com.
That's ask@alessifxhealth.com.
Until next time.
(36:53):
Stay curious, stay empowered, and remember,your health is in your hands.
Aging isn't just about getting older.
(00:02):
It's a biological process driven by specificcellular mechanisms.
While conventional wisdom says aging isinevitable, modern science has debunked that
and identified key drivers that speed it up,but more importantly, slow it down.
So let's break down the five biggest causes ofaging and what we can do about them.
Welcome to Health Decoded, your number onesource for real health information with your
(00:24):
host, Doctor.
Alessi and Matt Tack.
Alright.
Welcome back to another episode of HealthDecoded.
I am your host, doctor Alfred Alessi.
And today, we are going to talk about a reallycool topic and something that's very popular in
today's culture, especially with the prevalenceof so many chronic diseases on the rise.
(00:48):
We're gonna talk about anti aging and how wecan reverse cellular aging without having to
break the bank on expensive treatments.
And so, aging isn't really just about gettingolder, it's actually about how fast your cells
are breaking down.
So most people think of aging as an inevitableprocess.
They count the number of their birthdays,right?
(01:10):
And it's just a number that increases everyyear.
But what if I told you that the number ofcandles on your birthday cake doesn't actually
determine how old you are at the biologicallevel?
Aging isn't just about time passing, it's aboutthe rate of cellular breakdown inside your
body.
Some people in their 60s are still runningmarathons and thriving, while others in their
40s feel exhausted and have chronic joint pain.
(01:33):
And so what is the difference?
It's their biological age.
So your chronological age is simple it's howmany years you've been alive, but your
biological age, it's much more important.
It measures how well or how poorly your cellsorgans and tissues are functioning compared to
others of the same chronological age.
(01:53):
For example, a 50 year old with greatmitochondrial function, strong telomeres and
low inflammation could have a biological age of35.
Meanwhile, a 40 year old with high oxidativestress, insulin resistance and chronic
inflammation could have a biological age of 60.
And so what is the difference?
It's your cellular health.
(02:14):
So what drives biological aging?
Here's a few things.
Mitochondrial decline.
Mitochondria are the powerhouses of our cells.
So, this causes our cells to lose energyproduction, which can lead to fatigue and
disease over time.
Another one is telomere shortening.
So, the telomeres are the caps at the end ofyour DNA, and over time they can wear down,
(02:38):
which can lead to cellular dysfunction.
Chronic inflammation, which we have talkedabout in previous episodes is the silent killer
behind heart disease, dementia and cancer.
Things like glycation and insulin resistance.
So, basically sugar accumulating in the bloodover time can cause damage to proteins and
accelerate aging.
(02:58):
And then, probably one of the biggest ones isoxidative stress.
Oxidative stress is when things called freeradicals in the blood and in the cells can
attack your cells and cause premature aging.
And so there's a study in the Journal ofGerontology in 2021 found that people with
better mitochondrial function and lowerinflammation actually had biological ages up to
(03:20):
fifteen years younger than their chronologicalage.
And so, aging isn't about the calendar, it'sabout how fast your body is breaking down at
that cellular level.
And now what's the best part to this?
We can slow that down or reverse it.
And so what if you could slow, stop or evenreverse aging at the cellular level?
For decades, scientists believe aging was justinevitable.
(03:41):
But recent breakthroughs in longevity researchsuggest we can actually reverse many aspects of
aging.
Can we slow aging?
Absolutely.
Lifestyle, diet, and certain biohacks canactually dramatically reduce the rate of
cellular breakdown.
Now, can we stop aging?
Not completely, but we can delay major agingmarkers by decades.
(04:04):
How can we reverse aging?
In some cases we can by restoring mitochondrialfunction, clearing out what are called
senescent or zombie cells, and regeneratingtissues with stem cells or peptides.
A study in the journal Nature twenty twentyfound that hyperbaric oxygen therapy increased
telomere length by 20%, effectively reversingkey markers of aging.
(04:27):
So the future of aging is here.
Scientists are now exploring cutting edge waysto slow and reverse aging, including things
like NAD boosters to fuel the mitochondria,Things like senolytics which clear out old
damaged cells.
This is also doable with fasting.
Peptides and stem cells that regenerate tissuesthat have been damaged.
(04:50):
And then fasting and autophagy to triggercellular repair.
So aging just isn't something you have toaccept with the right strategies, you can take
control of your biological age, reverse it andslow the clock.
And so in this episode, I'm gonna break downwhat the science of anti aging is, not gimmicks
or expensive treatments, but cutting edgeresearch back ways to slow and even reverse
(05:13):
cellular aging.
So, the root causes of aging, how to stop them,the most powerful anti aging supplements that
actually work that have been studied andproven, Biohacks like red light therapy,
fasting, cold exposure, and then peptides, stemcells and regenerative medicine, how they work
and who should use them.
So, by the end of this episode, you'll walkaway with an action plan to not only live
(05:36):
longer, but to live stronger, healthier, andsharper for decades to come.
So let's dive in.
So like I discussed aging isn't just aboutgetting older.
It's a biological process driven by specificcellular mechanisms.
While conventional wisdom says aging isinevitable, modern science has debunked that
and identified key drivers that speed it up,but more importantly, slow it down.
(06:01):
So, let's break down the five biggest causes ofaging and what we can do about them.
So number one, mitochondrial dysfunction.
So this is basically the energy crisis ofaging.
Your mitochondria are like power plants in yourcells.
They produce energy, which is called ATP thatfuels everything from brain function to muscle
(06:22):
movement.
And as we age, the mitochondria become lessefficient, producing less energy and more
oxidative stress, which is a byproduct of thoseprocesses with inside.
This can lead to things like fatigue, cognitivedecline, and then even chronic disease.
So, does this happen?
Because the damaged mitochondria produce excessfree radicals, which cause damage
(06:44):
intracellularly.
Declining NAD plus levels can reducemitochondrial function because NAD is a
critical co enzyme that declines with age, andit was responsible for that production of ATP.
Things like toxins and poor diet can thenaccelerate mitochondrial breakdown.
So a study in the journal Nature 2020 foundthat mitochondrial decline is one of the
(07:08):
biggest drivers of aging and chronic disease,impacting everything from heart health to
neurodegeneration.
And so what is a solution for this boostingmitochondrial function with NAD plus precursors
things like NMN, NR, CoQ10, and specificallyexercise like HIIT training and strength
training.
We're going to get a little bit more into thisin the segment when we talk about solutions.
(07:32):
So what's number two on our list, telomereshortening.
So this is basically like a biological timebomb telomeres are the protective caps at the
end of your DNA strands, kind of like theplastic tips on the end of shoelaces.
Each time your cells divide, the telomeres getshorter until eventually they become too short
to function which can lead to cellulardysfunction and aging.
(07:54):
So, why does this happen?
Chronic stress and inflammation can acceleratetelomere loss.
Poor lifestyle choices, things like smoking,processed foods, sedentary life, they speed up
that shortening as well.
Oxidative stress damages DNA which leads to thepremature aging.
A study in The Lancet 2017 found that peoplewith longer telomeres had a significantly lower
(08:19):
risk of heart disease, dementia, and earlymortality.
So, what's the solution for this one?
Activating telomerase, which is the enzyme thatrepairs telomeres.
We can do this a few different ways things likefasting, meditation and mindfulness and
specific nutrients.
We'll get more into that third on the listchronic inflammation and oxidative stress.
(08:40):
We did an episode on this a few weeks backabout how these are the silent killers, and
basically responsible for a majority of chronicdisease.
Inflammation is a normal immune response, butchronic inflammation can wreak havoc on the
body.
It's linked to heart disease, diabetes, cancerand neurodegeneration.
So what spurs chronic inflammation things likea poor diet, high and processed sugars and
(09:05):
foods seed oils, chronic stress that triggersexcess cortisol and environmental toxins, like
pollution, heavy metals, which can acceleratethat oxidative damage.
A study in the Journal of Gerontology twentytwenty one found that people with lower
inflammation had biological ages up to fifteenyears younger.
(09:25):
So, what's an approach here is to follow ananti inflammatory diet.
Rich in Omega-3s, polyphenols and antioxidants.
Practicing intermittent fasting, giving yourgut a break, allowing it to lower that
inflammation, and using red light therapy tocombat inflammation as well.
Number four, cellular senescence.
The buildup of zombie cells.
(09:46):
So, as we age, our bodies accumulate senescentcells.
These are cells that are no longer functioningproperly but refuse to die.
So instead they linger in the body, secretingharmful compounds that can damage surrounding
tissues and accelerate aging.
So why does this happen?
Because these damaged cells fail to selfdestruct, which is called apoptosis.
(10:07):
It's a natural cellular process.
These senescent cells release things likeinflammatory chemicals, which can speed up the
aging and contribute to that process wediscussed.
And declining immune function allows thesezombie cells to accumulate.
So, a study done in Aging Cell Journal 2018found that clearing out senescent cells with
(10:28):
senolytic compounds, things like quercetin andfisetin, reversed biological aging markers in
mice and humans.
So what's the solution?
Using senolytics, things like we just saidquercetin, fisetin, resveratrol, and
intermittent fasting to promote a processcalled autophagy, which is your body's natural
cleanup process.
Number five, epigenetic changes.
(10:51):
Basically, the on off switch for aging genes.
So, your epigenome controls which genes getturned on or off based on lifestyle factors.
Where we have internal genetic predispositiondispositions based on our family history, the
DNA of our parents and those things.
Epigenetics is what our lifestyle and externalenvironment can contribute to our DNA.
(11:15):
So, is things like diet, exercise, stress.
As we age, harmful genes can get activatedwhile protective genes get suppressed, leading
to disease and dysfunction.
So, now why does this happen?
Toxins and poor diet trigger harmful geneexpression.
Chronic stress and poor sleep actually turn onthese genes that accelerate aging.
(11:38):
And lack of movement, sedentary lifestylesuppresses genes that will promote longevity.
A study done in the journal Cell twentynineteen found that lifestyle interventions
such as exercise, fasting and stress managementcould reverse these epigenetic markers of
aging.
So what's a key takeaway here for everything wejust discussed is that aging isn't inevitable.
(11:59):
It's a process that you can slow down, right?
And so, the latest research confirms that agingis not just wear and tear, it's driven by
specific cellular mechanisms, most that wedon't even know are happening, but that we can
influence with specific measures.
So, what does this mean for you?
Mitochondria can be strengthened with the rightnutrients and exercise.
(12:20):
Telomeres can be protected with stressreduction, things like Omega-three's.
Inflammation can be controlled with dietfasting biohacks.
Senescent cells can be cleared out withsenolytics and autophagy and your genes can
ultimately be reprogrammed for longevity withspecific lifestyle changes.
(12:41):
So, what's the bottom line?
Aging is no longer a mystery.
We know what causes it, but more importantly,we know how to slow it down.
And so, in this next segment, we're going todive into the most powerful tools, supplements
and even biohacks to reverse biological agingand keep your body and mind strong for decades
to come.
But first, here's a quick word from one of oursponsors.
(13:03):
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(14:18):
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Fentic Nutrition, fuel your best self.
Now back to the episode.
Alright.
Welcome back.
So if you wanna slow down aging, extend yourhealth span and keep your body functioning at
peak performance, certain nutrients andsupplements have been scientifically proven to
(14:38):
directly impact the aging process at thecellular level.
These compounds go beyond basic healthmaintenance, they actually repair your DNA and
optimize that mitochondrial function.
Doing things like reducing inflammation andmaking them essential tools in any anti aging
protocol.
So let's get into it.
Let's break down some of the most powerfulscience backed anti aging nutrients, and why
(15:02):
and how they work.
So number one on my list here is things likeNAD plus boosters.
These are NMN and NR, also known asnicotinamide mononucleotide or nicotinamide
riboside.
These are the ultimate cellular fuel.
So, NAD plus is one of the most criticalmolecules for longevity.
(15:23):
It's responsible for cellular energyproduction, DNA repair, and mitochondrial
health.
Unfortunately, NAD plus levels decline by 50%by middle age, leading to fatigue, cognitive
decline, and increased disease risk.
So, how it works.
NAD plus powers your mitochondria, which isyour body's power plant.
(15:45):
It activates DNA repair enzymes to preventcellular damage and enhances the activity of
things called sirtuins, which are proteins inthe body that extend lifespan and protect
against age related decline.
So, a study in the journal Cell Metabolism in2018 found that NMN supplementation reversed
(16:05):
age related vascular decline, restoring bloodflow and energy production to youthful levels.
So, are some of the best sources for NAD plusNMN, which is nicotinamide mononucleotide, and
NR, which is nicotinamide riboside.
These are the two best ways to boost NAD plusNext on my list here, Resveratrol and
(16:26):
Terrostilbene, the longevity gene activators.
So, Resveratrol is a more potent cousin andpterostilbene are powerful polyphenols that
activate sirtuins.
The same longevity genes stimulated by fastingand calorie restriction.
So how does it work?
Basically, it mimics the benefits of fastingwithout caloric restriction.
(16:50):
It's going to reduce oxidative stress thataccelerates cellular aging, and it's going to
protect the brain and heart by reducinginflammation.
So, a study out of Harvard University byDoctor.
David Sinclair showed that resveratrol mimicsthe benefits of fasting, activating sirtuins
and extending lifespan.
Some of the best sources for these are thingslike red grapes, blueberries, dark chocolate,
(17:14):
or supplementation for a higher dose effect.
Next on my list here, I have CoQ10 and PQQ, themitochondrial superchargers.
So, you want more energy, better endurance,improved brain function, Coenzyme Q10 and
Pyrroloquinoline quinine are essential.
These compounds enhance mitochondrial function,helping your bot your cells to produce ATP and
(17:36):
obviously energy more efficiently.
So, basically Co Q ten fuels mitochondrialproduction, while PQQ will stimulate the growth
of new mitochondria.
So, basically, it's a process calledmitochondrial biogenesis.
So, basically, these two in combination aregoing to enhance the way that your
mitochondrial grow and function, and protectthese cells from damage.
(17:58):
So a study in the Journal of ClinicalInvestigation 2015 found that CoQ10 improved
heart function and reduced fatigue in agingindividuals.
Some of the best sources for these are grassfed meat, fatty fish, certain nuts, or high
quality supplementation.
Next on my list here, and this was discussedheavily in the last two episodes, magnesium and
(18:20):
vitamin D three with K two.
These are anti inflammatory essentials.
Magnesium and D three K two work together tooptimize cellular function, improve bone
health, heart health, and regulateinflammation.
So, magnesium is the master co enzyme.
It's basically needed for over 300 enzymaticprocesses, including DNA repair and energy
(18:44):
production.
Whereas vitamin D3 paired with K2 work togetherto direct calcium where it belongs into the
bones, not into the arteries.
Both of these are going to reduce chronicinflammation, and then slow down those aging
related diseases.
A study out of the European Journal ofNutrition 2019 found that vitamin K two
(19:05):
supplementation reduced arterial stiffness byfifty percent, lowering heart disease risk.
So, some of the best sources, magnesium, youcan get from dark leafy greens, nuts, avocados,
vitamin D three and K two, obviously sunlight,certain fermented foods or you can always
supplement.
And so number five on this list is Omegathree's including EPA and DHA.
(19:30):
So, these are what we consider like a cellularshield.
The Omega three fatty acids are going tosupport brain health, reduce inflammation and
protect against cellular damage.
They are essential because the body cannotproduce them on its own.
So basically EPA fights inflammation,protecting cells from this oxidative stress,
and then DHA is going to support brainfunction, preventing against things like
(19:54):
neurodegeneration.
Both of these are going to enhancecardiovascular health, reducing the risk of
heart disease.
So I always recommend you get a good omegathree supplement that has a combination of EPA
and DHA.
So a study out of the American Journal ofClinical Nutrition in 2016 found that
increasing omega three intake reduced heartdisease risk by thirty percent.
(20:16):
Some of the best sources are going to be wildcaught fish like salmon and sardines, grass fed
beef, walnuts, or high quality fish oilsupplements.
So what's a key takeaway here is that thesenutrients don't just support health, they
actively reverse the aging process.
So, for you, what this means is you can boostNAD plus levels to restore cellular energy.
(20:39):
You can activate your longevity genes withresveratrol and fasting, supercharge
mitochondria with CoQ10, PQQ and magnesium.
Protect your arteries and brain health withvitamin D3, K2 and Omega 3s, and ultimately
slow inflammation and oxidative stress toextend your lifespan.
So the right supplements aren't just going tohelp you feel better, they're going work at the
(21:01):
cellular level to slow, stop, and even reverseaging.
So if you ever want to learn more about what wecall smart supplementation, and how to know
what's right for you, go to a lessee functionalhealth doc, book a consultation with me or one
of my amazing doctors, and learn how functionalmedicine can help you.
Now we're going to explore some of the morecutting edge advanced anti aging technology and
(21:26):
biohacks, from stem cells to peptides and more.
So if you're serious about slowing, stoppingand even reversing aging, advanced biohacks can
supercharge your results.
These aren't just gimmicks, these arescientifically backed interventions.
They're going to work with your body's naturalbiology to enhance your mitochondrial function,
(21:47):
regenerate tissues, lengthen your lifespan.
So, let's get into some of the more powerfulanti aging biohacks and the science behind
them.
Number one, you've probably all heard of thiscold therapy.
Cryotherapy, ice baths, cold showers.
Basically, these are the ultimate longevityreset.
Cold exposure activates something called brownfat, which boosts your metabolism, reducing
(22:13):
inflammation and stimulating the release oflongevity proteins like adiponectin.
It's also a powerful hormetic stressor.
Hormetic meaning a short controlled shock toyour system that triggers stronger cellular
repair mechanisms on the back end.
So how does it work?
When you get into the cold it activates whatare called cold shock proteins that are going
(22:34):
to enhance cellular resilience.
It's going to increase mitochondrialefficiency, leading to better energy
production, and it's going to reduceinflammation and oxidative stress.
So, a study out of the European Journal ofApplied Physiology in 2017 found that regular
cold exposure significantly increasedantioxidant defenses, helping cells fight
(22:56):
aging.
So how to do it?
Okay, take a thirty to sixty second cold showerafter a workout or in the morning when you
shower.
The best way to get into this is to start withwhat we call a cold finish.
You just took your shower, you're ready to go,thirty to sixty seconds of cold right at the
end.
To take it to the next level, you can trycryotherapy or ice baths, where you're going to
(23:17):
get your whole body emerged into cold, up tothree to five minutes at a time.
So now number two on this list, red lighttherapy using the process of
photobiomodulation.
This is going to reverse aging at the cellularlevel.
So red and near infrared light stimulatemitochondria to produce more ATP, helping cells
(23:38):
to repair damage, inflammation and enhancefunction.
So how does it work?
It's going to boost the mitochondrial function,increasing energy production at the cellular
level, enhancing collagen production, reducingwrinkles and skin aging.
That's awesome.
And it's going to improve cognitive function byincreasing blood flow to the brain.
(23:58):
So a study out of the Frontiers in AgingNeuroscience twenty twenty found that red light
therapy reversed age related cognitive declineand improved memory in older adults.
So how do we use it?
You can invest in a high quality red lighttherapy device, something like a Juve or a
MitoRed.
You can use that for ten to twenty minutes perday on the face, joints or the muscles for
(24:22):
cellular regeneration.
Or infrared sauna for full body mitochondrialactivation.
Highly, highly recommend infrared sauna.
Number three, very very powerful mechanism hereis intermittent fasting, or fasting mimicking
diets.
These are going to trigger the process ofcellular autophagy and regeneration.
(24:43):
So fasting isn't just for weight loss, itactivates autophagy, which is your body's built
in cellular cleanup process.
During fasting damaged proteins anddysfunctional cells are broken down, recycled,
leading to stronger healthier cells.
So how does it work?
Fasting triggers this autophagy process whichhelps the body to remove damaged cells.
(25:04):
The analogy I like to use is think of a busypost office.
If they're constantly getting new mail in, it'shard for them to process the mail that they
already have in the office to then get thatout.
So, you can take the break from putting foodinto the gut and into the body, it now has the
ability to take that damaged and old tissue,get that out, and regenerate what's needed.
(25:27):
Fasting is also going to lower insulinresistance, reducing the risk of metabolic
disease.
So a study in stem cell 2014 found that fastingfor seventy two hours could regenerate the
entire immune system, increasing stem cellactivity.
So how to do it.
Okay, and you have to be careful here if you'venever done it you want to start light.
(25:47):
So starting with what we consider a sixteeneight intermittent fasting.
So you're going to fast for about sixteenhours, and then you're going to schedule your
eating within an eight hour window.
Then once you've gotten good at that and youfound some balance your body can tolerate it,
then I would recommend you try going for moreof a twenty four to forty eight hour fast once
(26:08):
or twice a month for that deeper cellularcleanup.
Also experience experimenting with fastingmimicking diets for benefits without full
fasting.
We partner with a brand called Prolon where wecan use these specific formulas to still get
calories and nutrition in, but it mimics theconcept of fasting and allows the body to get
(26:28):
the benefits.
Next on the list here, and this is a little bitmore high-tech is hyperbaric oxygen therapy.
This is going to lengthen telomeres and reverseaging.
So hyperbaric oxygen therapy increases oxygenlevels in the tissues promoting cellular repair
and lengthening telomeres.
It enhances oxygen delivery, improves cellularrepair, boosts collagen production, which can
(26:51):
improve skin, joints and connective tissue, andit can increase stem cell production as well.
So, how to do it?
Okay, medical grade HBOT chambers, you would dofor about sixty-ninety minutes per session for
a deep rejuvenation.
You can use the soft HBOT chambers which arelower pressure at home.
Obviously these devices are not cheap.
(27:13):
There are places where you can go and do theseon a regular basis, two, three, four days a
month.
You can combine the HBOT with fasting for amore powerful synergy in this anti aging kick.
So, what's a key takeaway here?
Biohacking can unlock a lot of your body'snatural anti aging powers that have been
suppressed.
So, does this mean?
(27:33):
Cold therapy builds resilience, fightsinflammation.
Red light therapy supercharges themitochondria, reverses cognitive decline.
Fasting will trigger cellular cleanup andregenerate stem cells.
And hyperbaric oxygen can lengthen telomeresand reverse aging at the DNA level.
So what's the bottom line?
You don't need expensive unproven anti agingtreatments, because these cutting edge biohacks
(27:57):
work with your biology to extend lifespan andhealth span naturally.
So now, we're going to explore some moreadvanced regenerative therapies like peptides,
stem cells and gene therapy that are changingthe future of longevity.
So here we go.
Alright, so let's get into the role of peptidesand stem cells in anti aging.
(28:19):
So we've covered some natural strategies, somecutting edge biohacks, and now let's dive into
the next frontier of longevity.
Things that are really exciting, and that we'reexperimenting with at Alessi functional health
as well peptides and stem cells.
So these are powerful tools, and they have thepotential to regenerate tissue, enhance your
cellular repair, and extend your lifespan.
(28:40):
So, it's not just hype anymore, scientificstudies are proving that these therapies can
actively slow and reverse biological aging.
So peptides, which are basically the nextfrontier in longevity, what they are, they're
short chains of amino acids that act assignaling molecules in the body.
Unlike traditional pharmaceuticals, peptideswork with your body's natural processes to
(29:05):
enhance repair, recovery and longevity.
A peptide in particular, Epitalin, is known forextending lifespan at the genetic level.
What it does is a peptide that activatestelomerase, which is the enzyme responsible for
maintaining and lengthening your telomeres.
Longer telomeres are linked to increasedlifespan and reduced aging related disease.
(29:29):
A study out of the International Journal ofMolecular Science in 2019 found that Epitalin
increased longevity in animal models bypromoting telomerase activity.
So what it's going do is it's going to extendlifespan by maintaining the telomere length,
improve your sleep quality and circadianrhythm, and boost your immune function.
The next peptide, one that I've used a ton andrecommend to a lot of patients who come in with
(29:53):
joint pain and overall body pain is BPC-one 57.
This is the tissue regeneration peptide.
So, BPC-one 57 is a healing and recoverypowerhouse.
Originally discovered in the stomach, it's beenshown to rapidly regenerate tissues.
It can also heal the gut lining and reduceinflammation throughout the body.
(30:14):
Another reason we use it is for things likeleaky gut, or celiac disease.
So, the benefits are going to be that it'sgoing to heal muscle, ligament and tendon
injuries.
It's going to repair gut damage from conditionslike leaky gut and IBS, and it's going to
reduce overall inflammation and oxidativestress.
So then the next ones that are fantasticthymosin alpha one and thymosin beta four,
(30:36):
which are the ultimate immune and recoveryboosters.
You pair these with BPC one hundred fifty sevenand they basically double down on the effects.
So, these peptides are critical for immunefunction, wound healing, cellular repair.
Thymosin Alpha one enhances the immune systemstrength, helping the body fight infections and
slow aging.
Thymosin Beta four speeds up tissue repair,improving brain function, reducing
(30:59):
inflammation, all linked to aging.
So, who can benefit from this?
Those recovering from injury or surgery,individuals with weakened immune systems, or
those looking to reduce inflammation and slowaging.
So now let's talk a little bit about stem celltherapy and regenerative medicine.
Stem cells are awesome.
They're your body's raw materials forregeneration.
(31:21):
They have the ability to develop into any typeof cell and repair damaged tissue.
But as we age, our natural stem cell productiondeclines, leading to slower healing and
increased degeneration.
So mesenchymal stem cells or MSCs repair agingtissue.
They are powerful anti inflammatory andregenerative agents.
(31:42):
They're going to reduce those senescentmarkers, which is the damaged and aging cells.
They're going to go in and repair joints,muscles, nerves, and they're also going to
enhance skin and tissue regeneration.
So a study in the Journal of TranslationalMedicine 2018 found that mesenchymal stem cell
therapy rejuvenates aging tissue by reducingsenescent markers and promoting tissue repair.
(32:05):
So how do we use these, right?
In our clinic, we use them for jointregeneration, for things like arthritis and
cartilage repair, overuse injuries, forneurological conditions such as Parkinson's,
Alzheimer's, stroke recovery, and for whatwe're talking about today, the anti aging skin
and kind of cosmetic procedures as well.
Another way that we can activate stem cells isthrough something called softwave therapy.
(32:30):
So in our clinic at Alessi Functional Health,we have a device called a softwave therapy
unit.
This activates your body's own stem cells.
So rather than an injection, the soft wavetherapy is a non invasive regenerative
treatment that activates dormant stem cellswithin your body.
It's going to kick start healing and tissuerepair without surgery, drugs or injections.
(32:53):
So, how does it work?
It uses acoustic wave technology to stimulate amechanism within the body to promote tissue
repair.
This is going to activate dormant stem cells togo to the area.
It's also going to reduce inflammation andaccelerate recovery while lowering pain.
So, Softwave is really the future ofregenerative medicine without the high cost and
(33:14):
risk of stem cell injections.
Now when we pair the two together, we canenhance the results tenfold.
So, of the key takeaways here is that peptidesand stem cells are really the future for
longevity, anti aging and regenerativetherapies.
So peptides like Epitalin, BPC-one 57 andThymosin can actively reverse aging and enhance
(33:37):
recovery.
Stem cell therapy is gonna repair aging tissueand reduce inflammation, and soft wave therapy
is gonna stimulate your body's naturalregenerative powers without the injections.
Now, you use all three of these thingstogether, you are going to be an anti aging
recovering powerhouse.
And so we're no longer just managing aging,we're actually reversing aging at the cellular
(33:59):
level.
And so, as we wrap up here, I really want toleave you guys with some action and some things
that you can start today to kind of startslowing that aging process naturally and taking
more initiative.
So, this is what I'm going to call yourultimate anti aging blueprint.
Okay?
So, start incorporating some daily habits, suchas cold exposure, strength training, optimizing
(34:23):
your sleep.
Get some key supplements, things like NADboosters, Resveratrol and Omega-3s.
And then, look into some of the more advancedtherapies like red light therapy, fasting,
regenerative medicine.
And so at Alessi Functional Health, ourapproach is with functional medicine.
So with functional medicine, we create apersonalized protocol which combines the
(34:46):
cutting edge therapies like soft wave and stemcells, as well as the natural holistic methods
to activate your body's natural healingmechanisms and reverse aging from the cellular
level.
So, in conclusion, the future of aging is notjust about living longer, it's about living
better, stronger and sharper.
So, aging is optional.
(35:08):
And so, if you're curious about creating apersonalized plan for lifelong cellular health
and longevity, schedule a consultation.
Go to a lesseefunctionalhealth You can book aconsultation right on the website, sign up for
our newsletter, check out our resources page,learn more about our approach, and how we use
these cutting edge therapies.
(35:30):
Listeners of the Health Decoded podcast aregoing to get exclusive discounts and price
reductions on all supplements, blood work, andeven therapies.
So as always, if you found value in today'sshow, please like and smash that subscribe
button.
Share this episode with someone who needs tohear it.
That's the only way we get the word out is ifyou share and you spread the word.
(35:51):
And if you wanna get in touch with us or evenbe featured on an episode, email us, send us
questions to ask at Alessi FX Health dot com.
We might answer those live on the show.
As always, thank you for tuning in to HealthDecoded, where we break down the science, bust
the myths, and help you take control of yourhealth naturally.
(36:11):
Until next time, stay curious, stay empowered,and remember, your health is in your hands.
Thank you for tuning in to Health Decoded,where we break down the truth about all things
health and empower you to take charge of yourwell-being.
If you found value in today's episode, pleasesubscribe, leave a review, and share it with
someone who needs to hear this.
(36:33):
For more resources and personalized support,visit us at AlessifunctionalHealth.com and sign
up for our newsletter.
To hear your questions answered live on theshow, send them to askalessifxhealth dot com.
That's ask@alessifxhealth.com.
Until next time.
(36:53):
Stay curious, stay empowered, and remember,your health is in your hands.
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