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February 12, 2025 44 mins

When Nature Calls is a cutting-edge center for self-optimization in the heart of Amsterdam. What began as one of the city's first smart shops in 1998 and has taken the knowledge of the industry, plants and uses and has expanded into an elevated, holistic space blending self optimization, plant medicine, and modern and ancient wellness practices. 

The founder of the space Patrick De Jongh shares his journey from spotting a business opportunity in psychedelics when he was in his 20’s  to pioneering an intentional, safe and evidence based experience for those seeking mental and physical well-being in a more expanded way. Haylin, with a background in neuroscience, brings a fresh, evidence-based perspective, making When Nature Calls on the cutting edge of using natural and evidence based methods to optimize wellness in a more holistic way.

There is a shifting perception on psychedelics and non psychoactive microdosing and usage that is powerful and important and it is bringing these ancient and modern approaches—from underground to mainstream, 

Microdosing is only the start, set and setting can apply to an entire lifestyle so  the importance of accessible yet high-quality wellness spaces is important.  When Nature Calls also is passionate about their community-first approach that is also next level and a often a missing part of the puzzle. Patrick and Haylin envision expanding their concept internationally, creating destination retreats and centers in other places where science, nature, and self-discovery align.

In this episode:

  • Smart Shop to Self-Optimization Sanctuary: Patrick shares how When Nature Calls evolved beyond psychedelics into a holistic wellness destination.
  • The Power of Set & Setting: Haylin emphasizes how their intentional, design-forward space makes plant medicine approachable and transformative.
  • The Rise of Microdosing & Mental Well-being: The shift from recreational to int

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