ImmunoCAST

ImmunoCAST

From medical guidelines and best practices to educational insights on specific disease states, ImmunoCAST is a podcast dedicated to providing healthcare providers of all specialties clinically relevant, easy-to-digest episodes on allergy related topics.

Episodes

July 9, 2025 28 mins
As spring allergies subside, clinicians face a new wave of allergy challenges. This episode tackles the often-overlooked summer allergy surge, addressing the shift from tree pollen to grass and ragweed pollen. We explore the critical distinction between Class 1 and Class 2 food allergies, shedding light on cross-reactivity with summer fruits and vegetables. The discussion covers unexpected allergen sources like dust mites in air co...
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Dive into the fascinating world of allergen components and how modifying them is revolutionizing food safety for allergy sufferers. We explore the unexpected ways allergen components affect food allergenicity, and how this knowledge is being leveraged to create safer options. From alpha-Gal-free pigs to ovomucoid-free eggs, we discuss groundbreaking developments in modified foods. We also cover the latest research on reducing aller...
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Did you know that urban planners inadvertently created allergy hotspots by favoring male trees in city landscapes? This episode of ImmunoCAST takes listeners on a cross-country journey, exploring how allergies manifest differently across various US regions. We address the challenge of identifying and managing region-specific allergens, from urban environments to coastal areas and the heartland. Topics covered include the impact of ...
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Did you know the average person unknowingly consumes about 2 pounds of insects or insect parts annually? This startling fact underscores the ubiquitous presence of insects in our environment and diet, presenting unique challenges in allergy diagnosis and patient management. This episode of ImmunoCAST explores the multifaceted world of insect-related allergies, moving beyond common respiratory or stinging triggers to uncover lesser-...
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Many of the 33 million Americans affected by food allergies, start their allergy care journey with a visit to their primary care or family medicine clinician. Tune in as Dr. Ruchi Gupta, a board-certified pediatrician and founding director of the Center for Food Allergy and Asthma Research (CFAAR), shares key insights on the current state of food allergies in America as well as impactful diagnostic and management tips that every pr...
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In this episode of ImmunoCAST, we share an example of impactful patient education from our friends at Allergy Insider (@allergyinsider). They hosted Dr. Zachary Rubin (@rubin_allergy), a double board-certified pediatrician and allergist and internet sensation, and ImmunoCAST’s own Gary Falcetano, PA, on their recent Instagram Live segment “Ask the Insider” to discuss the allergy symptom threshold.

Because Allergy Insider aims to pro...

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This spring, patients may be reporting that some foods cause their mouth to itch. Is this a food allergy? Or is this pollen food allergy syndrome (PFAS)? In this episode of ImmunoCAST tackles the clinical challenge of distinguishing this condition from more severe food allergies. We explore the mechanisms behind PFAS, its relationship to seasonal allergies, and the importance of comprehensive allergy evaluation. Key topics include ...
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In partnership with Food Allergy Research & Education (FARE), Gary Falcetano discusses the unique challenges of diagnosing and managing Alpha-gal syndrome (AGS), a red meat allergy triggered by tick bites with Dr. Scott Commins, a leading expert in Alpha-gal syndrome (AGS) and distinguished professor at the university of North Carolina. They explore the distinct nature of Alpha-gal as a carbohydrate allergen, the prolonged jour...
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Coming out of the winter months and flu season, we dive into the best ways to help prepare patients with asthma for the spring allergy season. From insights into the impact of allergies and viral illnesses on patients with asthma to ways to help reduce exposure to potential allergic triggers, tune in and gain important information on how you can help optimize patient outcomes going into spring. Episode resources and references av...
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Dr. David Golden is a member of the Joint Task Force on Practice Parameters and has directed research programs on insect allergy and anaphylaxis at Johns Hopkins for 30 years, publishing numerous research and review articles. In this episode we speak with Dr. Golden about the latest updates to the anaphylaxis practice parameters, emphasizing critical changes in recommendations around the role of epinephrine and more. Transitioning ...
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This is part 2 of ImmunoCAST, highlighting interesting abstracts presented at the American College of Allergy, Asthma, and Immunology’s 2024 meeting. In this episode, we explore nine allergy-related medical case studies that were showcased and piqued our interest. Tune in and discover some of the fascinating ways allergies may present in your patients and what you can do to optimize your diagnosis and management. From shrimp exposu...
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ImmunoCAST visited the 2024 American College of Allergy, Asthma, and Immunology meeting and collected some of the most interesting and important research papers which were unveiled during the conference. Whether you’re an allergist or a primary care clinician, tune in to hear some of the most exciting research and insights that are coming out of the field of allergy, including the role of climate change on latex allergy, the role o...
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With almost half a million followers on Instagram and over 1.3 million followers on TikTok, allergist Dr. Zachary Rubin has built a huge following of users interested in his allergy insights. Tune in as we interview Dr. Rubin to understand the role of a clinician online, best practices for combating online misconceptions, and how he leverages digital platforms to deliver accurate allergy and immunology education. We also get advice...
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Because ethanol is too small of a molecule for the body to make antibodies to, there really is no such thing as an "alcohol allergy," but that doesn't mean patients can't have a reaction to substances found within alcohol. In this episode of ImmunoCAST, we address the clinical challenge of distinguishing between alcohol intolerance and true allergy. Tune in as we explore histamine intolerance, sulfite sensitivity, and ALDH2 deficie...
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Halloween presents unique challenges for clinicians managing patients with food allergies. In this episode, to heighten awareness and preparedness, we explore the emotional impact on children with food allergies, who may often feel excluded from Halloween activities, as well as emphasize the importance of an accurate diagnosis using component resolved diagnostic blood tests to help identify exactly what with in an allergen may be c...
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When we picture a patient struggling with respiratory allergies, our mind might immediately jump to spring allergy season. However, fall allergies, while often overlooked, can cause patients to experience reactions just as severe due to the combination of outdoor triggers and viral season. Tune in as we discuss the history of ragweed, its impact on public health, and its connection to oral allergy syndrome. We also dive into the ro...
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ImmunoCAST welcomes Dr. Michael Benninger, Professor and Former Chair of the Department of Otolaryngology-Head and Neck Surgery in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, as a guest expert speaker on this special Allergy After Dark episode. With over 200 publications, Dr. Benninger is an expert on respiratory allergies and their impact on sexual function in patients. Tune in to this episo...
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Does your patient have a food allergy or intolerance? Celiac disease or wheat allergy? When it comes intolerances vs. allergies, there’s a lot of symptoms overlap. In this episode of ImmunoCAST, we discuss the mechanisms and differences behind IgE-mediated food allergies, autoimmune conditions like celiac disease, and various types of food intolerances, including metabolic, pharmacologic, and toxic reactions. We also dive into the ...
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Using the Triple Aim framework to dissect the current status of allergy care in America, this episode delves into the per capita cost, population health, and patient experience of care, emphasizing the importance of accurate diagnosis and appropriate referrals. Tune in for insights on improving healthcare efficiency, reducing costs, and enhancing patient outcomes. Don't miss this informative episode designed to help clinicians bett...
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Asthma Peak Week is nearly a month away, giving clinicians just enough time to start to help prepare their at-risk patients. Tune into this episode of ImmunoCAST where we break down why in September there is a spike in asthma exacerbations and hospitalizations as well as some tips and insights on how to ensure your patients with asthma are prepared and safe in the coming month. Episode resources and references available at https://...
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