ImmunoCAST

ImmunoCAST

From medical guidelines and best practices to educational insights on specific disease states, ImmunoCAST is a podcast dedicated to providing healthcare providers of all specialties clinically relevant, easy-to-digest episodes on allergy related topics.

Episodes

From Clinic to Lab: The Allergy Diagnostic Journey

August 21, 2025 • 32 mins
Did you know that IgE, the antibody responsible for allergic reactions, is 30,000 times less abundant than other immunoglobulins in the body? This staggering fact underscores the importance of highly sensitive allergy diagnostics. In this episode, we pull back the curtain on what happens to allergy diagnostic blood samples after they leave your clinic. Clinical laboratory expert Jessica Murphy, MLS (ASCP), guides us through the int...
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Rural Allergy Risks: A Clinical Examination of Horse Allergy and Beyond

August 5, 2025 • 23 mins
Did you know that 27 million Americans ride horses annually, surpassing both golf and tennis in popularity? This surprising statistic underscores the widespread exposure to potential horse allergens, even in urban areas. In this episode, we tackle the allergies commonly seen in rural environments. We explore the intriguing hygiene hypothesis, comparing asthma rates in Amish and Hutterite communities, and uncover the unexpected prev...
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Unraveling the Complexities of Pet Allergy Diagnosis with Dr. Ann-Marie Schoos

July 22, 2025 • 24 mins
This episode dives into the intricate world of pet allergies, exploring how testing with allergen components is reshaping our clinical approach to diagnosis and management. Dr. Anne-Marie Schoos, a pediatrician and clinical researcher, shares insights on interpreting sensitization profiles, the predictive value of multiple component sensitizations, and the surprising specificity of male dog allergies. Learn about the clinical benef...
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Summer Allergy Surge: From Summer Camp to Air Conditioners

July 9, 2025 • 28 mins
As spring allergies subside, clinicians face a new wave of allergy challenges. This episode tackles the often-overlooked summer allergy surge, addressing the shift from tree pollen to grass and ragweed pollen. We explore the critical distinction between Class 1 and Class 2 food allergies, shedding light on cross-reactivity with summer fruits and vegetables. The discussion covers unexpected allergen sources like dust mites in air co...
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How Are Allergen Components Reshaping Food Allergy Safety for Patients?

June 24, 2025 • 30 mins
Dive into the fascinating world of allergen components and how modifying them is revolutionizing food safety for allergy sufferers. We explore the unexpected ways allergen components affect food allergenicity, and how this knowledge is being leveraged to create safer options. From alpha-Gal-free pigs to ovomucoid-free eggs, we discuss groundbreaking developments in modified foods. We also cover the latest research on reducing aller...
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Allergies Coast to Coast: Uncovering Regional Triggers and Treatments

May 28, 2025 • 27 mins
Did you know that urban planners inadvertently created allergy hotspots by favoring male trees in city landscapes? This episode of ImmunoCAST takes listeners on a cross-country journey, exploring how allergies manifest differently across various US regions. We address the challenge of identifying and managing region-specific allergens, from urban environments to coastal areas and the heartland. Topics covered include the impact of ...
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Dust mites to dinner plates: Unexpected insect allergies in clinical practice

May 5, 2025 • 20 mins
Did you know the average person unknowingly consumes about 2 pounds of insects or insect parts annually? This startling fact underscores the ubiquitous presence of insects in our environment and diet, presenting unique challenges in allergy diagnosis and patient management. This episode of ImmunoCAST explores the multifaceted world of insect-related allergies, moving beyond common respiratory or stinging triggers to uncover lesser-...
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Transcript

Must-Know Tips for Primary Care Managing Food Allergies: Insights from Dr. Ruchi Gupta

April 24, 2025 • 25 mins
Many of the 33 million Americans affected by food allergies, start their allergy care journey with a visit to their primary care or family medicine clinician. Tune in as Dr. Ruchi Gupta, a board-certified pediatrician and founding director of the Center for Food Allergy and Asthma Research (CFAAR), shares key insights on the current state of food allergies in America as well as impactful diagnostic and management tips that every pr...
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Understanding the Allergy Symptom Threshold with Dr. Zachary Rubin and Allergy Insider

April 10, 2025 • 21 mins

In this episode of ImmunoCAST, we share an example of impactful patient education from our friends at Allergy Insider (@allergyinsider). They hosted Dr. Zachary Rubin (@rubin_allergy), a double board-certified pediatrician and allergist and internet sensation, and ImmunoCAST’s own Gary Falcetano, PA, on their recent Instagram Live segment “Ask the Insider” to discuss the allergy symptom threshold.

Because Allergy Insider aims to pro...

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Transcript

From Pollen to Plate: Understanding Pollen Food Allergy Syndrome

March 17, 2025 • 18 mins
This spring, patients may be reporting that some foods cause their mouth to itch. Is this a food allergy? Or is this pollen food allergy syndrome (PFAS)? In this episode of ImmunoCAST tackles the clinical challenge of distinguishing this condition from more severe food allergies. We explore the mechanisms behind PFAS, its relationship to seasonal allergies, and the importance of comprehensive allergy evaluation. Key topics include ...
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Why Tick Season Isn’t the Only Time to Focus on Alpha-gal Syndrome with Dr. Scott Commins

March 11, 2025 • 52 mins
In partnership with Food Allergy Research & Education (FARE), Gary Falcetano discusses the unique challenges of diagnosing and managing Alpha-gal syndrome (AGS), a red meat allergy triggered by tick bites with Dr. Scott Commins, a leading expert in Alpha-gal syndrome (AGS) and distinguished professor at the university of North Carolina. They explore the distinct nature of Alpha-gal as a carbohydrate allergen, the prolonged jour...
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Preparing Asthma Patients for Spring: Strategies and Insights

February 19, 2025 • 19 mins
Coming out of the winter months and flu season, we dive into the best ways to help prepare patients with asthma for the spring allergy season. From insights into the impact of allergies and viral illnesses on patients with asthma to ways to help reduce exposure to potential allergic triggers, tune in and gain important information on how you can help optimize patient outcomes going into spring. Episode resources and references av...
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Dr. David Golden Discusses the Latest Anaphylaxis Guidelines and More

February 3, 2025 • 31 mins
Dr. David Golden is a member of the Joint Task Force on Practice Parameters and has directed research programs on insect allergy and anaphylaxis at Johns Hopkins for 30 years, publishing numerous research and review articles. In this episode we speak with Dr. Golden about the latest updates to the anaphylaxis practice parameters, emphasizing critical changes in recommendations around the role of epinephrine and more. Transitioning ...
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Thought-provoking medical case studies showcased at ACAAI 2024

December 16, 2024 • 31 mins
This is part 2 of ImmunoCAST, highlighting interesting abstracts presented at the American College of Allergy, Asthma, and Immunology’s 2024 meeting. In this episode, we explore nine allergy-related medical case studies that were showcased and piqued our interest. Tune in and discover some of the fascinating ways allergies may present in your patients and what you can do to optimize your diagnosis and management. From shrimp exposu...
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Highlighting 9 of the most interesting research abstracts from ACAAI

December 2, 2024 • 20 mins
ImmunoCAST visited the 2024 American College of Allergy, Asthma, and Immunology meeting and collected some of the most interesting and important research papers which were unveiled during the conference. Whether you’re an allergist or a primary care clinician, tune in to hear some of the most exciting research and insights that are coming out of the field of allergy, including the role of climate change on latex allergy, the role o...
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Navigating Social Media as a Clinician: Insights from Dr. Zachary Rubin

November 18, 2024 • 23 mins
With almost half a million followers on Instagram and over 1.3 million followers on TikTok, allergist Dr. Zachary Rubin has built a huge following of users interested in his allergy insights. Tune in as we interview Dr. Rubin to understand the role of a clinician online, best practices for combating online misconceptions, and how he leverages digital platforms to deliver accurate allergy and immunology education. We also get advice...
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Understanding Alcohol and Allergies: Hidden Risks and Reactions

November 4, 2024 • 22 mins
Because ethanol is too small of a molecule for the body to make antibodies to, there really is no such thing as an "alcohol allergy," but that doesn't mean patients can't have a reaction to substances found within alcohol. In this episode of ImmunoCAST, we address the clinical challenge of distinguishing between alcohol intolerance and true allergy. Tune in as we explore histamine intolerance, sulfite sensitivity, and ALDH2 deficie...
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Food Allergies & Halloween: Balancing Emotional and Physical Health

October 23, 2024 • 16 mins
Halloween presents unique challenges for clinicians managing patients with food allergies. In this episode, to heighten awareness and preparedness, we explore the emotional impact on children with food allergies, who may often feel excluded from Halloween activities, as well as emphasize the importance of an accurate diagnosis using component resolved diagnostic blood tests to help identify exactly what with in an allergen may be c...
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The Overlooked Allergy Season: Challenges with Fall Allergies

October 7, 2024 • 14 mins
When we picture a patient struggling with respiratory allergies, our mind might immediately jump to spring allergy season. However, fall allergies, while often overlooked, can cause patients to experience reactions just as severe due to the combination of outdoor triggers and viral season. Tune in as we discuss the history of ragweed, its impact on public health, and its connection to oral allergy syndrome. We also dive into the ro...
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Exploring Allergic Rhinitis and Sexual Health with Dr. Michael Benninger

September 23, 2024 • 16 mins
ImmunoCAST welcomes Dr. Michael Benninger, Professor and Former Chair of the Department of Otolaryngology-Head and Neck Surgery in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, as a guest expert speaker on this special Allergy After Dark episode. With over 200 publications, Dr. Benninger is an expert on respiratory allergies and their impact on sexual function in patients. Tune in to this episo...
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