Cellular Zip Codes and Cancer Care: David Loynd on Endurex’s Breakthrough Delivery Platform | Ep. 12
In this episode of Industry Ignited, Dr. Leeanne Aguilar interviews David Loynd, President & CEO of Endurex Pharmaceuticals, on how a peptide-directed nanoparticle drug delivery platform—built around “cellular zip codes”—targets tumors while sparing healthy tissue. Drawing on engineering discipline, systems thinking, and partnerships with institutions like MD Anderson, David explains why traditional chemotherapy’s systemic toxicity falls short and how Endurex localizes payloads to hard-to-treat cancers such as triple-negative breast cancer, ovarian cancer, and glioblastoma. We dive into manufacturing-minded optimization (design of experiments, polymeric nanocarriers), scale-up paths (microfluidics, impinging-jet, or patient-specific small-scale units), and a pipeline that extends beyond chemo to immunotherapies, RNA/antisense cargos, and vaccine delivery. The result: potential for higher efficacy, lower toxicity, improved patient experience, and scalable systems that move from invention to impact. If you’re in biotech, pharma operations, or industrial process design, this conversation is a masterclass in precision delivery, process innovation, and commercialization strategy.
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Dateline NBC
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Cardiac Cowboys
The heart was always off-limits to surgeons. Cutting into it spelled instant death for the patient. That is, until a ragtag group of doctors scattered across the Midwest and Texas decided to throw out the rule book. Working in makeshift laboratories and home garages, using medical devices made from scavenged machine parts and beer tubes, these men and women invented the field of open heart surgery. Odds are, someone you know is alive because of them. So why has history left them behind? Presented by Chris Pine, CARDIAC COWBOYS tells the gripping true story behind the birth of heart surgery, and the young, Greatest Generation doctors who made it happen. For years, they competed and feuded, racing to be the first, the best, and the most prolific. Some appeared on the cover of Time Magazine, operated on kings and advised presidents. Others ended up disgraced, penniless, and convicted of felonies. Together, they ignited a revolution in medicine, and changed the world.