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September 15, 2025 67 mins

I'm joined by my good friend, Li-Lian Ang, first hire and product manager at BlueDot Impact. We discuss how BlueDot has evolved from their original course offerings to a new "defense-in-depth" approach, which focuses on three core threat models: reduced oversight in high risk scenarios (e.g. accelerated warfare), catastrophic terrorism (e.g. rogue actors with bioweapons), and the concentration of wealth and power (e.g. supercharged surveillance states). On top of that, we cover how BlueDot's strategies account for and reduce the negative impacts of common issues in AI safety, including exclusionary tendencies, elitism, and echo chambers.

2025.09.15: Learn more about how to make design effective interventions to make AI go well and potentially even get funded for it on BlueDot Impact's AGI Strategy course! BlueDot is also hiring, so if you think you’d be a good fit, I definitely recommend applying; I had a great experience when I contracted as a course facilitator. If you do end up applying, let them know you found out about the opportunity from the podcast!


Follow Li-Lian on LinkedIn, and look at more of her work on her blog!

As part of my effort to make this whole podcasting thing more sustainable, I have created a Kairos.fm Patreon which includes an extended version of this episode. Supporting gets you access to these extended cuts, as well as other perks in development.


  • (03:23) - Meeting Through the Course
  • (05:46) - Eating Your Own Dog Food
  • (13:13) - Impact Acceleration
  • (22:13) - Breaking Out of the AI Safety Mold
  • (26:06) - Bluedot’s Risk Framework
  • (41:38) - Dangers of "Frontier" Models
  • (54:06) - The Need for AI Safety Advocates
  • (01:00:11) - Hot Takes and Pet Peeves

Links

Defense-in-Depth

  • BlueDot Impact blogpost - Our vision for comprehensive AI safety training
  • Engineering for Humans blogpost - The Swiss cheese model: Designing to reduce catastrophic losses
  • Open Journal of Safety Science and Technology article - The Evolution of Defense in Depth Approach: A Cross Sectorial Analysis

X-clusion and X-risk

  • Nature article - AI Safety for Everyone
  • Ben Kuhn blogpost - On being welcoming
  • Reflective Altruism blogpost - Belonging (Part 1: That Bostrom email)

AIxBio

  • RAND report - The Operational Risks of AI in Large-Scale Biological Attacks
  • OpenAI "publication" (press release) - Building an early warning system for LLM-aided biological threat creation
  • Anthropic Frontier AI Red Team blogpost - Why do we take LLMs seriously as a potential source of biorisk?
  • Kevin Esvelt preprint - Foundation models may exhibit staged progression in novel CBRN threat disclosure
  • Anthropic press release - Activating AI Safety Level 3 protections

Persuasive AI

  • Preprint - Lies, Damned Lies, and Distributional Language Statistics: Persuasion and Deception with Large Language Models
  • Nature Human Behavior article - On the conversational persuasiveness of GPT-4
  • Preprint - Large Language Models Are More Persuasive Than Incentivized Human Persuaders

AI, Anthropomorphization, and Mental Health

  • Western News article - Expert insight: Humanlike cha
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