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August 27, 2025 89 mins

In this episode of Iron Culture, hosts Eric Trexler and Eric Helms discuss various topics including the ongoing debate about the relationship between muscle growth and strength gains. They discuss brand new findings from the largest and longest-running study on resistance training, explore the implications of "apparent" sex differences in strength gains, and emphasize the need for nuanced statistical analysis in understanding the factors that contribute to strength gains and observed sex differences.


Want to read a thorough analysis of the article we discussed in this episode (and many more)? Support the show by joining the MASS Community at massresearchreview.com


Chapters

00:00 Intro

09:10 The Debate on Muscle Size and Strength

12:30 New Research on Muscle Strength and Size

20:45 Exploring Sex Differences in Muscle Training

26:40 The Hierarchy of Evidence in Research

32:00 Relationships Between Strength And Muscle Size

36:40 Lifting For Sport: History And Changing Cultural Norms

39:00 Back To The Study Results (Understanding Sex Differences in Strength Gains)

42:15 Nuances of Statistical Analysis: Relationships Between Strength And Muscle Size

54:10 Aside About Collegiate Sports In USA

56:50 Causal Discovery Analysis in Strength Research

1:08:00 Summary and Conclusions: The Role of Muscle Growth in Strength Gains

1:21:45 Listener Question: Sample Sizes in Exercise Science

1:27:10 Outro

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