June 21, 2024 • 57 mins
In this episode of the Ketones and Coffee Podcast, host Lorenz welcomes Dr. Thomas Seyfried, a scientist renowned for his pioneering research into cancer and metabolic diseases. Dr. Seyfried, who holds a Ph.D. in Genetics and Biochemistry, discusses his controversial theory that cancer is not a genetic but a mitochondrial metabolic disease.
Dr. Seyfried underscores the inconsistency he found in existing research and the potential of non-toxic therapies like calorie restriction and ketogenic diets to manage cancer. He provides compelling evidence and case studies, arguing for a paradigm shift in cancer treatment. This episode offers listeners an insightful exploration of alternative cancer therapies and the need for a broader acceptance within the medical community.
00:00 Introduction and Guest Welcome
00:14 Dr. Seyfried's Background and Research Focus
02:52 Challenging the Genetic Theory of Cancer
04:35 The Role of Mitochondria in Cancer
15:14 Historical Context and Paradigm Shift
22:42 Metabolic Dysfunction and Cancer Development
29:12 Understanding Mitochondria and Chronic Diseases
29:43 Targeting Cancer Metabolism
30:04 The Role of DNA Mutations and ROS
31:27 Strategic Glutamine Targeting
31:53 Ketosis and Cancer Treatment
33:21 Challenges in the Medical Community
36:07 Hybrid Cancer Treatments
37:31 Patient Involvement in Metabolic Therapy
38:20 Success Stories and Documentary Efforts
40:03 The Future of Cancer Treatment
41:05 Addressing the Medical Community's Resistance
43:23 The Need for Metabolic Therapy Awareness
Support Dr. Seyfried! https://foundationformetaboliccancertherapies.com/
You can support him in multiple ways:
- Buy his summary book: https://www.amazon.com/dp/B0CLJQ13F2
- Buy his scientific book: https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920
~~~~~~
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
0613 (00:00):
Hey guys.
Welcome to the ketones andcoffee podcast.
I'm Lawrence, and I'm sograteful to have you joining me
on this journey.
Every week I bring in guests tohave the knowledge and
experience to help you on yourown journey to a better health.
I'm so excited for this guystoday.
We're We have an honor ofhosting Dr.
Thomas Seyfried, a distinguishedscientist whose groundbreaking
(00:20):
research has reshapedunderstanding of cancer and
metabolic diseases.
Dr.
Seyfried received his Ph.
D.
in genetics and biochemistryfrom the University of Illinois.
Throughout his career, Dr.
Dr.
Siegfried has received numerousaccolades from prestigious
organizations, such as theNational Institute of Health and
(00:41):
the American Society ofNeurochemistry.
His research focuses on geneenvironment interactions related
to complex diseases withsignificant contributions to the
field of epilepsy, autism, braincancer, and neurodegenerative
diseases.
It's an honor, Dr.
Thomas Siegfried.
Welcome to the Ketones Coffeepodcast.
squadcaster-a27a_1_06-13-20 (01:03):
Oh, thank you very much, Lance.
It's very nice to be here today.
0613 (01:06):
is nice to finally grace your presence here on the
podcast.
How are you?
How are things?
What are you excited abouttoday?
squadcaster-a27a_1_06-13- (01:13):
Well, today happens to be a very nice
day.
Very low humidity might get upabout 85.
I'll go over to the gym afterthis, relax do a few things.
And we have a faculty meetingthis afternoon outside.
So that should be interesting.
0613 (01:28):
Very exciting.
Very exciting.
You know, I've had a lot of manyinterviews on my show, but
really I am starstruck bysomeone's presence.
A little hiccup on the beginningthere, but you know, with my
connection issues, but solelysometimes, you know, your impact
on other people's lives.
I mean, the topic we are aboutto discuss today, sir, your own
(01:48):
personal mission, your book.
Cancer as a metabolic disease.
As I was, you know, examiningthe reviews about the book,
countless individuals hasreported life changing effects
and a lot of them say lifesaving.
If anyone of you, someone dearto you is struggling with cancer
(02:11):
or maybe you yourself, thisepisode is for you.
Sir Thomas Seyfried, the wordcancer itself does something to
us that no other word can.
You know, it's, it's one of themost devastating disease known
to man.
The current research tells usthat some of us are genetically
(02:32):
predisposed to developingcancer.
And we all know someone that is,has been affected by this
disease, but you offer a newtheory, one that doesn't need to
be.
Chemotherapy, radiation, evensurgery all at once, right?
And we got a lot to discusshere.
You say cancer is primarily amitochondrial metabolic disease.
(02:57):
That offers hope.
I mean, first of all, what hasled you to the research,
specifically moving away fromthe theory that it's not a
genetic disease, but rather ametabolic disease?
Tell us that story.
squadcaster-a27a_1_06-13- (03:11):
Okay.
So, yeah, well, that's certainlywould be a paradigm change for
sure.
But you have to look at all ofthe facts and evidence, and then
you have to, there's several,several things you well,
required me to know before Icould suggest that the paradigm,
the current paradigm isincorrect and as you said, I
have a degree in genetics andbiochemistry you have to have a,
(03:35):
a foundational understanding ofevolutionary biology, And, and
you have to be familiar with theoriginal work of Otto Warburg.
So, and you need to do theresearch experiments yourself to
test ideas directly in your lab.
You don't rely on what otherssay.
You do the experiments yourselfand you see what the results
(03:56):
happen to be.
And that's what we do.
So, Like everyone, almosteveryone I thought cancer was a
genetic disease.
I mean, we had this in all ofour research lectures that we
get whether they're departmentalseminars, whether in the
textbooks of biology, cellbiology or biochemistry, you can
(04:16):
pick up any one of them andthey'll say that cancer is a
genetic disease.
And then of course, on theNational Cancer Institute
website at the NIH.
It says cancer is a geneticdisease.
Who am I to question, toquestion the prevailing view the
dogma the silent assumption.
But I, I started seriouslyquestioning that when I started
(04:39):
to see research in my own labthat treating animals that have
tumors with calorie restricteddiets cause significant
reduction.
in the rate of growth theinflammation around the tumor
and many other and the increaseddeath of tumor cells.
And it, and we, we, we, welinked that to a reduction in
(05:02):
blood glucose levels.
And I thought this was a greatobservation.
And then I realized that OttoWarburg had made similar
suggestions in the 1920s and30s, publishing a seminal review
paper in 1956, clearly sayingthat cancer was a metabolic
problem, not a genetic problem.
(05:23):
Problem is the field thatalready spent billions of
dollars hunting for genes incancer.
And there's no question thatmany, many, most cancer cells
have genetic mutations.
We're not, this is a fact.
Cancer cells, most of them havegenetic mutations.
But the question is, are thosemutations responsible for the
dysregulated cell growth, or isit some problem with energy
(05:46):
metabolism.
And of course the geneticistssay the, the abnormal energy
metabolism is caused by the genemutations.
On the other hand, that's hardto understand how gene mutations
could actually influence theamount of ATP energy within the
cell, because that was amitochondrial driven process.
So it turns out that you know, Istarted to look at this and do a
(06:10):
deep dive on Warburg's theory.
And it turns out that Warburgsaid all cancers initiate from
an insufficiency of oxidativephosphorylation linked or
coupled to a compensatory energythrough substrate, or I should
say fermentation.
Fermentation is energy withoutoxygen.
So, and, and we know this,everybody knows this.
(06:33):
So, okay, we have gene mutationsand we have tumor cells arising
or can live without oxygen.
And, you know, it's veryinteresting.
I always tell everybody this.
If you take cyanide, you know,it's cyanide, it's a very toxic
poison.
Cyanide kills people veryquickly, animals, any, any, any
organism.
That's using oxidativephosphorylation, breathing air
(06:56):
to get energy cyanide blocksthat and shuts it down and, and
will kill very, very quickly.
Can Warburg said a long timeago, and we validated what he
said.
Cancer cells live in cyanide,can live in the presence of
cyanide.
That tells me right there,they're not using oxygen for
energy and they also grow in theabsence of oxygen.
This is hypoxia.
So cancer cells, well, how arethey growing and living?
(07:18):
without using oxygen as a sourceof like we breathe oxygen and,
and we generate energy.
We exhale CO2, the breakdownproducts.
These damn cancer cells are,are, are living without, without
oxygen.
That's very interesting.
So, and it turns out Warburgsaid because their mitochondria
are defective and people say, Ohno, Warburg was wrong.
(07:40):
Most of the field says becausecancer cells consume oxygen
also.
But the problem with the cancercells, they're taking, consuming
oxygen, but they're not using itfor energy.
This is what, what we foundwhich then throws a stick in the
spoke of the field.
And then we went back and wefound some papers saying they
can't find any mutations in somecancer cells.
(08:01):
Well, that, that's notconsistent with the somatic
mutation theory of cancer.
So then they said, The field, ofcourse, says, Oh, well, not all
mutations are causing cancer.
Only the driver mutations causecancer.
These are the really importantones.
So new research now is tellingus that we have driver mutations
and all through our body thatnever, in cells that never form
(08:22):
cancer.
So that's inconsistent againwith the theory.
Every major cancer we've lookedat has damage in number,
structure and function ofmitochondria.
That seems to be thecommonality.
And then you say, well, wheredid all these mutations come
from?
And the answer is when oxygencomes into a tumor cell, not
using it for energy.
They form reactive oxygenspecies called, these are
(08:44):
reactive radicals and theydamage DNA, RNA, and proteins.
So the mutations that we see incancer cells that the field is
constantly targeting or lookingat are all downstream effects.
So, We spent billions andbillions of dollars in the
cancer genome projects with thehope that we would find
(09:05):
mutations Causing dysregulatedgrowth and we could target those
mutations and therefore bring anew realm to cancer management
Well that has been a almostcomplete failure It hasn't
worked.
So consequently We persist intreating cancer patients with
toxic poisonous chemicals,radiation, and surgical
(09:25):
mutilation, because the promiseof the genomic theory, the
somatic mutation theory beingfinding targeted mutation has
not come to pass.
And that's because cancer is nota genetic disease.
It's a mitochondrial metabolic.
What does that mean?
All cancer cells must get energyfrom.
fermentation, which is energywithout oxygen.
(09:46):
So the question then, what dothey, what's driving this
fermentation energy?
And we and others have foundit's glucose and glutamine.
The sugar glucose and the aminoacid glutamine are both
fermented to generate ATP energyfor the dysregulated growth.
And they can't burn fatty acidsor ketone bodies.
Cancer cells cannot live onfatty acids or ketone bodies in
(10:10):
the absence of glucose andglutamine.
So that tells us clearly how tomanage cancer without toxicity.
Problem is the rest of the worldhas not opened their eyes or
understood what I have just
0613 (10:20):
Simple.
You've, you've explained that tome within five minutes and I, I
could understand it.
It's, it's simple and there'sevidence there, and it is you,
you know, I feel like theinconsistency you found in the
research drove you to seekinganswers.
But I wanna know why were youexamining.
(10:42):
Caloric restrictions versus theprogression of cancer or the
growth of cancer.
What, what, what initiated that?
Glutamine.
squadcaster-a27a_1_06-13 (10:50):
found, we worked in the field of
epilepsy for years and we knewand we knew that ketogenic
restricted ketogenic, I was, Ishowed, the folks that the
ketogenic diet was working andkill and Children predominantly
because it was lowering bloodsugar.
And when we were lowering andthe kids would eat ketogenic
diets and their epilepsy wouldgo away, why did the epilepsy go
(11:11):
away?
And the answer is because wereduced blood sugar and elevated
ketones.
And you can see a child thatmight be managed without having.
seizures will drink a glass ofsweet orange juice or something
like that, and within within 30minutes, they'll explode into an
epileptic seizure and theirblood sugar shoots up and then
they explode into an epilepticseizure.
(11:32):
So it was clear to us that themanagement of epileptic Epilepsy
in children using theseketogenic diets was related to
the lowering of glucose and theelevation of ketones.
But the mechanism in the brainby which lowering glucose and
elevating ketones blockselectrical excitability in parts
of the brain.
The, the, the molecularmechanisms for that are still
not completely known.
(11:53):
However, the cancer.
We know exactly what's going on.
Very close to the understandingmore completely than, than
epilepsy for sure.
When you lower the blood sugar,cancer cells need fermentable
fuels.
Glucose is a prime fermentablefuel.
And therefore you're shuttingdown one part of their energy
metabolism.
The other part, which wasn'tclear, at the beginning to us
(12:15):
how that was working wasfermentation of the amino acid
glutamine and Warburg knewnothing about that either.
And therefore he ran into a lotof controversy and a lot of
misunderstanding because hecouldn't figure out where some
of these cancer cells, eventhough your lower blood sugar
really low, they were stillhanging on and still growing.
Why, where are they gettingtheir energy from?
(12:36):
And he didn't know about theglutamine issue.
And now we were the oneseverybody knew glutamine.
They all thought it wasrespired.
We're now showing that theglutamine is fermented, which
means getting glutamine, theenergy out of glutamine without
oxygen.
That's the big breakthrough inthe cancer field, as far as I
can see which Warburg did notknow about.
And right now the 90, 95 or 99percent of the cancer field also
(12:59):
cannot understand that theyeither can't understand it or
they can't believe it.
Yet we have evidence now, wejust published a major paper on
this, and my, my colleagueChristos Xenopoulos from
Semmelweis University, he hasdocumented this in cancer cells.
So we have clearly now, we knowhow cancer cells are getting
energy for the dysregulatedgrowth.
So all we have to do is targetthe availability of the energy
(13:22):
and you can shut down thesetumor cells for the most part.
0613 (13:24):
We'll talk about glutamine there in a second.
I want to break this down forour listeners here.
I want to talk about metabolic,this metabolic theory that we
have here.
Obviously there's a lot ofevidence showing that you know,
showing a lot of promise.
A lot of people are talkingabout how you know, this.
is a life changingtransformation, right?
Just, just reading your book,Cancer as a Metabolic Disease,
(13:47):
you outlined the data on thatbook from 2013, 2017, the
percentage increase for cancerdeaths is greater than the
increase for newer cases.
And you call it a failure of, ofmonumental proportions.
I mean, something is off.
And, and You, you found a wayto, to finally you know, seek
(14:11):
answers and, you know, basicallyyou're seeing we're losing the
war and your research showsthat, that there is a
fundamental misunderstanding ofwhat the nature of the disease
is.
Right.
And you're basically saying wegot it all wrong.
What cancer really originatesfrom and what can be argued
about it is being the reason whyit's only getting worse.
(14:32):
But I wanted to ask you, how didthey get it wrong?
If the research seems conclusiveof the evidence, that is, it's a
genetic disease, right?
It's when you read the researchpapers, it seems very
conclusive, right?
What made you challenge theconventional wisdom there?
I know we talked about youstarting from, you know, your
(14:55):
studies with epilepsy, right?
And, and, and you connected thatto how our understanding of
where cancer originates from.
Did they get it or wrong?
I, I wanna, I wanna know theirperspective and how are they not
open to this idea?
Mm-Hmm.
squadcaster-a27a_1_06-13- (15:14):
Well, those are very important
questions.
And they go to the core ofscience of how science advances.
And I look at it very similar tothe Copernican revolution.
When for 1800 years scientistsand astronomers thought that the
earth was the center of the, ofthe solar system.
(15:36):
The work of Aristotle andPtolemy and other astronomers at
that time could not completelyexplain how planets and
celestial bodies, their, their,their motion through the heavens
was always challenged.
And the field and the systems.
Kept doing more and more studiesto try to better, better
(15:59):
calculate how, how heavenlybodies were moving.
But there was always someproblem that could not explain
clearly how everything wasmoving.
But they persisted and persistedand persisted for 1800 years in
doing these experiments thatwere never able to completely
define this until untilCopernicus realized that if we,
(16:20):
if the earth is in fact movingand travels around the sun
together with the other planets,you could actually explain the
mathematics and you couldexplain the movement.
We're in a very similarsituation here with cancer.
The field has becomeindoctrinated and dogmatic in,
and believing that, thatmutations are the origin of the
(16:40):
dysregulated cell growth.
The strongest evidence to saythat cannot be the case is the
nuclear mitochondrial transferexperiments, which I've
published in my book.
And I wrote a paper on thisspecifically showing the field
that if you take the nucleus outof a tumor cell.
that has all the mutations inthe nucleus that are supposed to
(17:01):
drive the dysregulated growth,and you transplant that nucleus
into a, into a non cancerouscytoplasm containing normal
mitochondria, the, the results,the offspring, of those cells
have normal growth.
They don't have dysregulatedgrowth, even though the
mutations in the nucleus stillthere are there.
(17:22):
On the other hand, if you, ifyou take the normal, the nucleus
from a normal cell andtransplanted to a cytoplasm, a
tumor cell cytoplasm withabnormal mitochondria, the
offspring of those, is isneoplastic dysregulated cell
growth.
So clearly the origin ofdysregulated cell growth resides
in the cytoplasm with themitochondria, not in the nucleus
(17:44):
with the genetic mutations.
That's the strongest evidence.
That's the same power of, ofCopernicus putting putting the
sun in the center of the solarsystem.
It's, it's, it's that powerful.
Now, of course, what happenedwhen Copernicus did that?
Galileo immediately started touse the telescope to confirm
Copernicus's theory and washouse arrested.
(18:07):
Giordano Bruno an Italianscientist was burned at the
stake for challenging theCatholic Church's dominance over
what we should think and what weshould know getting back.
So how is it possible that thecancer field, a multi billion
dollar industry, fails torecognize the that their efforts
to manage cancer is incompletebecause they think it's a
(18:30):
genetic disease.
They're locked into the samedogmatic view.
How could they all be wrong?
Confirmation bias says they notbe wrong.
If they, if the federalgovernments of the United
States, Canada, Germany, Japan,England, all of these guys are
saying cancer is a geneticdisease.
Who the hell am I to come andchallenge them?
(18:50):
All I did was look at the data.
I let them disprove what I'msaying.
It's not me.
They have to try to disprove theevidence that's clearly shows
that cancer cannot be a geneticdisease.
Yes, cancer cells havemutations.
We all know that, but they arenot the cause.
They're the effect of the damageto the respiration.
So once you realize, then youcan move forward.
(19:13):
with therapies and treatmentsthat are non toxic and
powerfully effective to manageit.
Because you're now doing what,they can't live without
fermentation fuels.
That's the, they can't livewithout that.
So you just have to target that.
And there's no clinical trials,there's no treatment programs or
any of this that's testing whatI'm saying.
(19:35):
Because who's going to testthis, the pharmaceutical
companies that are makingbillions of dollars on drugs
based on the somatic mutationtheory, all those
immunotherapies, who's going totest this?
The hospitals, they're lockedinto making great revenue from
radiation and chemo and all thisother stuff.
Who wants to test a theory thatcould potentially reduce revenue
(19:57):
generation for the majority ofthese institutions, grants to
the, to the scientists from thethe, so what we're saying.
So you have to, what we did,what people do in the past is
you ignore what I'm saying.
That's the easiest thing.
And the simple, oh, it hasn'tbeen repeated.
It has been repeated numeroustimes.
You should choose not to look atthe data.
Oh, and no clinical trials.
(20:17):
Oh, why don't you do a clinicaltrial after you train, train the
folks?
Oh, we can't do that.
Everything is, we can't, wecan't.
We can't, we can't, okay?
So when you get the deniers, andthe so news sayers, and all
those other guys out of the way,those guys just gotta out of the
way, let us move forward andwe'll be able to I'm not saying
we can cure cancer, all I'msaying is we can provide an
(20:38):
outcome far superior to whatpeople are currently
experiencing today.
0613 (20:43):
And it's, and, and since you've compared it to, you know,
18 hundreds you know, research,it's bound to change.
Right.
And you alluded to the fact thatit is, it, it all comes back to
the lack of knowledge on thebiology of the disease.
Right.
From your,
squadcaster-a27a_1_06-13- (21:00):
Well, it's not that they have a lack
of knowledge.
These guys are well educatedfolks.
They're very smart.
They just are working under anincorrect theory, okay?
That's the key.
It's the theory that drives theunderstanding of the biology.
If the theory says that canceris a genetic disease, you're
focusing on gene mutations.
(21:22):
You're not focusing onmitochondrial insufficiency of
oxidative phosphorylation or thedependency of those cells on the
two fuels.
And when I tell folks that, whydon't you take away the glucose
and glutamine in the media thatyou're studying?
They say, we can't do thatbecause the cancer cells will
all die.
And I said, yeah, that's the,that's the, that's the whole
thing.
You won't have anything to studyif you take away the two fuels
(21:43):
that drive the dysregulatedgrowth.
Now you have to play this inthe, in the living system, of
course.
And we've worked out the presspulse therapeutic strategy,
which adopts that concept totreating cancer patients.
So, and it's working on the, onthe people that are doing it in
the isolated places where theydo it.
Most of them, not all of them,most of them get do much better.
(22:05):
The cancer goes either becomesmuch reduced in rate of growth
or it goes into some sort ofstabilized state and sometimes
might go away at least for the,the, the, the short term.
But we've, people are there.
I don't know how many yearsPablo Kelly's out 10 years now.
His cancer never went away.
a brain tumor.
He's had three surgeries on aglioblastoma, but he's still
(22:27):
alive.
You know, you don't usually livebut a, a year or two with that.
And he's out 10 years now.
So did it, was he cured now?
Is he living a hell of a lotlonger than everybody else?
You're damn right.
He is.
0613 (22:39):
And it's a classic, they're not looking in the right
place.
Right.
From your research on the canceras a metabolic disease, in your
view of this disease, where itoriginates as a metabolic
dysfunction, how does that leadto the development and
progression of cancer nowstarting as a metabolic
(22:59):
dysfunction, where, where doesthat, Now we've identified where
it's actually originating, buthow does that lead to the
development of cancer?
squadcaster-a27a_1_06-13- (23:09):
Yeah.
So let's look at the theprovocative agents that we all
know are car, are carcinogenic,the term chemical carcinogen.
Why do they call a chemical acarcinogen?
Because it causes cancer.
Okay.
Asbestos.
And we found you know, varioustetra, these various chemicals,
you know, we have, we call themcarcinogens.
(23:29):
So I went through all the listof carcinogens and every one of
them damages the structure andfunction of the mitochondria,
the organelle responsible forgenerating energy through
oxygen.
So In the case of a carcinogen,what happens is the energy
coming out of the mitochondriais compromised.
And in order for the cell tostay alive, it has to compensate
(23:51):
with upregulation of substratelevel phosphorylation, which is
an alternative source tooxidative phosphorylation.
I don't want to get toocomplicated on this.
It's just a fermentationmetabolism.
Okay.
Now what is What controls thedifferentiated quiescent state?
Suppose, suppose you have yourliver, for example we'll use
(24:13):
that as an organ and it'sexposed to chemical carcinogen.
And all of a sudden you see apopulation of cells growing out
of control in the liver.
What, what caused those normalliver cuboidal cells,
hepatocytes, let's say, to grow?
to start growing out of control.
So when you look at them, youfind that the mitochondria are
(24:34):
dysfunctional and damaged andthey're fermenting.
Okay.
How did that happen?
How did the chemical carcinogencause a bunch of cells in the
liver to start growing out ofcontrol?
So what is the organelle thatcontrols the stable and
differentiated state?
And it's the mitochondria.
The mitochondria control thecell cycle.
So the normal a metabolicallystable homeostatic state of the
(24:58):
cell is controlled by themitochondria.
That organelle controls the cellcycle.
Now, when that organelle becomescorrupted, the cell falls back
on a fermentation mechanism,fermentation.
Now you have to realize this iswhy you need to know
evolutionary biology.
Before oxygen came into the,onto the atmosphere of our
planet was completely a noxious.
There was no oxygen in theoriginal beginning earth of the
(25:20):
earth two, two and a halfbillion years ago, two and a
half billion years ago, we hadcells that were developed that
were growing on the planet.
Some of these organisms, single,single cell organisms, everybody
was fermenting.
All those cells were fermentingand they were growing in a
dysregulated way dysregulatedcell growth with a fermentation
metabolism.
(25:40):
The cancer cell.
is going back and expressing thesame characteristics as these
original cells that existed on afermentation.
Why are they growing out ofcontrol?
Because the organelle that'ssupposed to control their growth
now is dysfunctional and thecells fall back on these ancient
pathways of fermentation.
And when you look at cancer,every major cancer is throwing
(26:00):
out massive amounts of lacticacid and succinic acid, the
waste products of a fermentationmetabolism becomes clear.
So these cells are doing nothingmore than falling back on
ancient metabolic pathways thatexisted before oxygen came into
the atmosphere.
These pathways exist in all ofour cells, but they're very
subdued.
They don't play a big rolebecause we're breathing air.
(26:21):
But but when we stop, when we,when our mitochondria become
chronically damaged, not acutelydamaged, acutely damaged, the
cell will die.
You'll never get a cancer cell.
But if it, but if the cell hasthe opportunity to upregulate
fermentation, it loses growthcontrol and starts growing out
of control.
Now that's chemical carcinogen.
What about oncogenic viruseslike hepatitis virus,
papillomaviruses?
(26:42):
They do the same thing.
They chronically damagemitochondria.
What about radiation?
Radiation we know can causecancer.
Well, that chronically damagesmitochondria.
What about intermittent hypoxia?
What about these things.
What about the BRCA1?
What about those written geneticrisk factors that we hear about?
P53, BRCA1.
These are inherited riskfactors, right?
(27:02):
So they damage the structure andfunction of the mitochondria
leading to dysregulated cellgrowth either in the breast or
some other organ, right?
The liver h Uh, BRCA1 can be thebreast cancer mutations that you
hear about, but they damagemitochondria.
If the BRCA1 doesn't damagemitochondria, that, that person
can have the mutation and neverdevelop, never develop the
cancer.
(27:22):
It only happens when themitochondria develop.
Cancer is very unlikely to occurif the mitochondria can remain
functional and, and normal.
Let's put it that way.
So, normal, normal generation ofenergy through oxidative
phosphorylation is normalfunctioning mitochondria.
When that becomes compromised,they start to ferment and they
(27:43):
lose their control, their growthcontrol, and they grow out of
control.
And what's the energy?
It's a fermentation energy.
What do you mean?
They're using, they're usingancient pathways.
Well, what's driving thoseancient pathways?
Glucose and glutamine.
How do you know?
Because we tested it all, weinterrogated all the other
fuels, and glucose and glutamineare the two prime fuels that are
responsible for the dysregulatedgrowth.
(28:04):
Why?
Because the mitochondria are nolonger functional, so therefore
they must ferment.
So this is, and so you feed themketones and feed them fatty
acids, they can't use ketones infatty acids.
Why?
Because these fuels are non,they can't be used for
fermentation.
They're non fermentable fuels.
But the normal cells in the bodycan.
can burn ketones and fattyacids.
(28:25):
So we just transition the wholebody.
to ketones and fatty acids,tumor cells can't use them, and
then you come in and you targetthe glucose and glutamine
simultaneously and startslaughtering these tumor cells
without toxicity.
How does that sound?
0613 (28:39):
Good.
I mean, two more cells cannotuse ketones, right?
But are actually preferred bythe healthy cells.
So you're killing off cancersand healing the body at the same
time, basically.
squadcaster-a27a_1_06-13 (28:51):
That's right.
That's right.
And when you use metabolicketogenic metabolic therapies
you not only get rid of we, thepeople that we see oftentimes
have type two diabetes, they'reobese, they have all kinds of
other hypertension and all thiskind of stuff.
A lot of that stuff goes away.
along with the cancer becausethey're all suffering from a
chronic problem, the chronicenergy disruption.
(29:12):
And in some kinds that causesdysregulated cell growth.
Other times it causes type twodiabetes, hypertension, all
these cardiovascular diseasedementia.
It's unbelievable.
So as long as you can keep yourmitochondria healthy you can
avoid a lot of the chronicdiseases.
The pro the problem is our dietand lifestyle today.
Often stand in the way is anobstacle to prevent us from
(29:32):
getting cancer in the firstplace.
So, we, we, but you know, mostpeople want to know, what are
you going to do for me after Iget the tumor?
I know I should have been a goodboy and a good girl and I should
have never done what I did, butI got cancer.
Now, what are you going to dofor me now?
We have to target the glucoseand glutamine and transition
your whole body off totherapeutic ketosis.
0613 (29:49):
Yeah.
Yeah.
So that that's, so you're sayinglike cancer feeds on glucose,
right?
The idea which is one of thereasons why extended fasting has
become so popular with cancerpatients as an alternative
treatment to how about, howabout DNA mutation?
How does that fit in the, in thetheory?
squadcaster-a27a_1_06-13- (30:08):
Yeah.
Well, when the when the cancer,if the mitochondria become
defective and they take inoxygen, the oxygen forms rat
Ross reactive oxygen species.
These are hydroxide ions superoxides.
These are damaging radicals.
They cause the mutations in theDNA.
So the mutations in the DNA,what is the provocative agent
(30:29):
causing the mutations in theDNA?
And that's ROS.
ROS are carcinogenic andmutagenic.
Hundreds and hundreds of papersin the scientific literature
showing that ROS, R O S, arecarcinogenic and mutagenic.
Okay?
Carcinogenic and mutagenic.
So where, and that produce,where do they produce?
They produce in damagedrespiration, damaged
mitochondria.
(30:50):
Disfunction of mitochondria thatare insufficient in oxidative
phosphorylation form these RAS.
The RAS then damage the DNAcausing the mutations that
everybody's all excited to seeand chase.
But they're all downstreameffects of the damage to the
oxidative phosphorylation.
So, so, and how are the cellsgrowing?
They're growing like crazy withall these DNA mutations.
So, so what's driving thereanyway?
(31:12):
How are they growing with allthese mutations?
Because they're fermenting.
What are they fermenting?
Glucose and glutamine.
Why don't we take away theglucose and glutamine and we can
kill the cell regardless of themutations they have in the
nucleus.
And that's exactly what we see.
0613 (31:23):
Okay.
So we know how to take awayglucose.
How do we take away glutamine?
squadcaster-a27a_1_06-13-202 (31:27):
We have to use, we have to be very
strategic.
Because glutamine is, is, isconsidered a non essential amino
acid, but for the cancer cell inthe immune system, it's an
essential amino acid.
Yes.
So you have to be strategic.
Dosage, timing, and schedule.
You can't go in there as anignoramus, as a bull in a china
shop and just try to take awayeverybody's glutamine.
(31:48):
You strategically target it andthen pull off.
Target and pull off while youkeep the choke hold on the
glucose.
We don't need glucose glucose,but we can replace glucose with
ketone bodies There was aninteresting study some years ago
by by the scientist Drenic.
He took morbidly obese guys Andhe fasted them for 21 days Where
(32:08):
their blood sugar went down andtheir ketones went way up And
then he injected them withinsulin.
Can you believe this?
So whatever little glucose wasin their bloodstream, it kind of
disappeared.
It went down to nine milligramsper decaliter, which everybody
would consider death.
0.
5 millimole.
I mean, this is like barelydetectable.
These guys are walking aroundfine.
(32:29):
No cognitive decline noabnormalities.
And, and, and it was because thebrain and the rest of the cells
switched over to fatty acids andketone brain burns, fatty ketone
bodies, liver can burn fattyacids.
So it shows you how low you canget glucose.
And then the normal cells ofyour body will take up what
little glucose might beavailable, starving, indirectly
(32:52):
starving the cancer cell of itsglucose.
And that, but it can still hangon because it might suck down a
little bit and ferment a littlebit of the glutamine.
So then you just pulse theglutamine with glutamine drugs
and some of these drugs areparasites Antiparasite drugs
turns out that the cancer cellsand the parasites use a common
metabolic pathway So if you killparasites, you can kill cancer
cells with the same drug.
(33:12):
It's not this stuff isunbelievable I mean if the field
knew what I just said we wouldbe dropping the death rate of
these cancer patientsSignificantly within a very
short period of time.
The problem is what I just toldyou either doesn't want to be
recognized, it's toocomplicated, or I don't want to
know about it.
You know who wants to know aboutwhat I'm saying?
(33:34):
The cancer patients want to knowwhat I'm saying.
But you go to the oncologistsand they have never heard of
anything that I had just said,and many of them don't even want
to know about it.
They think glucose has no rolein cancer.
They think fasting has no rolein cancer.
Never heard of glutamine issue.
They, they say, oh no, eatinfomel, eat candy and all this
kind of stuff.
I mean, this tells you how farout of, out of, out of, out of
(33:57):
touch The oncology community isand these are good folks.
They've just been they've justbeen trained the wrong way They
want to help their patients nothurt their patients, but they've
just Haven't had thisinformation in their training
and once they do we're going tosee a monster change very rapid
change in the outcome
0613 (34:15):
I mean, you did call it the future of cancer treatment.
squadcaster-a27a_1_06-13-20 (34:20):
Oh, absolutely Absolutely.
It will be the new standard ofcare.
It's just, it's just has to beunderstood.
And your job is to sometimesthese podcasts push the
information out where, wherewill the change come?
That's the question.
The change must come from the,from the patients themselves.
The change must come from thepopulation of people.
(34:43):
that suffer the greatest fromthis.
It's not going to come, I don'tthink, from the top medical
schools or the pharmaceuticalindustry because they have too
much, they're comfortable,they're very comfortable in
their current status.
And I get calls from dozens anddozens of physicians who
actually get cancer.
and they're stage four.
They're, they're coming to me toget information on how to manage
(35:06):
their cancer because radiationand chemo and surgical
mutilations, they, theycertainly can help some people.
But even if you survive that youpay a significant price, your
body has been poisoned andradiated and mutilated.
And your quality of life is, youknow, sometimes not always
optimal after surviving toxictreatments, whereas metabolic
(35:29):
therapy can eliminate a lot ofthat.
And the other thing you have torealize we don't throw out all
the standards of care.
We're finding that thesechemicals, these chemotherapies,
maybe even immunotherapies andradiation therapy have a much
greater therapeutic benefitwhen, when the patient is in
nutritional ketosis.
So even getting the patientinto, not only will the patient
(35:51):
start killing their tumor cells,they'll be much more responsive
to the chemicals and treatmentsof the standard of care.
So it's going to be a hybridtransformation as we move from,
from, from an incorrect theoryto the correct theory of what
the disorder actually is.
0613 (36:06):
so what does that look like?
A hybrid treatment.
So we combine the drugs thattarget glutamine and then a
ketogenic therapy, whicheliminates
squadcaster-a27a_1_06-13- (36:14):
Yeah, yeah.
What we do is we bring patientsin and we do a comprehensive
blood work.
We find out how, how close orfar they are from optimal
physiological state, what wecall optimal metabolic state.
We have to bring that patientback into some level of
metabolic homeostasis.
And once they're in thismetabolic, and that could be
(36:34):
eating Zero carb diets for aweek or two.
You can start to see the, theglucose go down, the ketones go
up, the patient generally getshealthier.
Then you bring in either sta mestandards of care some chemicals
that are currently being used,or you can use small dose of
radiation depending on the typeof tumor that it is.
Everything responds better whenthe patient is in nutritional
(36:55):
ketosis.
And then you can bring in theglutamine targeting drugs.
And that has to be.
Known.
We, we, dosage timing andscheduling have to be optimized.
And that's what we're doing herein my lab is we're optimizing
dosage timing and scheduling forthe different diet drug combos,
which will eventually be thestandard of care.
Patients are going to have toknow this.
There's no pill.
(37:16):
that will be able to do whatmetabolic therapy can do, but a
pill can work remarkably wellwith metabolic therapy.
So it has to be a combinationbecause don't forget it took a
long time for that person to gofrom a state of health to ill
health and having cancer.
So you're, you're to, to, toturn that whole system around
requires some effort on the partof the patient.
(37:36):
So the patients themselves haveto play a role.
a significant role in thetransformation of their body
from ill health to health.
So they, in order to havesuccess, the patient must play a
significant role in thisprocess.
They're no longer sitting thereas bystanders for being treated
with chemicals and radiation.
With metabolic therapy, a largepart of the success depends on
(37:59):
the motivation of the patient.
0613 (38:01):
That's right.
That's right.
So there are a lot oftestimonials from countless.
You know, success stories, andyou, you already alluded to one,
any specific success storiesanother success story that come
in mind you might share with ustoday.
squadcaster-a27a_1_06-13- (38:20):
Well, we have Maggie Jones who's
writing the cancer revolution.
Doctor got documentary.
They're producing a professionaldocumentary.
Brad Jones, the husband, Brad isa professional movie maker in
the documentary field, andthey're collecting dozens and
dozens of for terminal cancerpatients and having every one of
(38:42):
those stories told by the, bythose patients.
And you know, all of them in oneway or another lowered glucose
and elevated ketones.
And then they did a variety ofother things with certain
supplements that work togetherother dietary things.
So they're collecting all ofthe, all of these testimonials,
if you will, and anecdotes.
And there's and we have to havetrained, but you can't start
(39:05):
doing large clinical trialswithout having a knowledgeable
practitioner running the trial.
And so, so right now we're justcollecting person after person,
after person, after person, andthey have brain cancer, colon
cancer, lung cancer, breastcancer pancreatic cancer.
We've written on that prostatecancer, bladder cancer
(39:26):
melanomas.
blood cancer, the whole range ofblood cancers.
We're, we're, we're seeing thesame overall outcome with a
variety of cancers because,because all major cancers have
to rely on fermentation forgrowth.
So the same therapeutic strategyis effective against all the
major cancers because all majorcancers are similar.
(39:46):
They need fermentation forgrowth.
And we, and how do we know that?
I, I published a major papershowing that all major cancers
have abnormalities in the numberstructure and function of the
mitochondria.
That means they all have toferment.
Therefore, they're all dependenton glucose and glutamine to some
extent.
So this then becomes a clearstrategy for moving the entire
field forward in the correctdirection, because it's based on
(40:09):
the correct theory of what thenature of the disease is.
0613 (40:12):
I mean, with this type of promise, and we're seeing a lot
of results here, it's not a warbetween science and cancer.
I think it's more of the medicalcommunity accepting the shift
away from conventional toxictreatments towards metabolic
therapies.
Would you agree?
It's I think it's, it's, it'smore, more that than just
(40:35):
cancer.
I mean, if, if we're seeing alot of great results with
individuals with cancer even inlater stages of cancer, get you
know, reversing or even, youknow, healing from that.
Isn't that the war is just, ifthey just accept a lot of people
(40:56):
will be saved.
Like, that's what I feel.
squadcaster-a27a_1_06-13-20 (41:00):
No, you're 100 percent correct.
So now, here's a, here's a achore for you.
Go, you're in Toronto, okay?
They have a large cancer centerin Toronto.
Why don't you go down and askthe guys there, how come you're
not doing metabolic therapy?
And you'll get, there's noevidence to support that.
Well, did they read thescientific literature showing
(41:20):
all the detailed experimentalexperiments that.
We and others have done tosupport that.
No, I haven't read it.
Well, what makes you say thatthere's no evidence to support
it?
Because if it's people will theysay well If it was really
important, I would have heardabout it.
Well, you are hearing about it.
You're doing nothing about it Imean, it's just i'm telling you
about it
0613 (41:39):
Okay.
squadcaster-a27a_1_06-13-20 (41:40):
And yeah, well, I don't believe you
okay, he doesn't believe meWell, did you read the
scientific evidence to supportnow?
I don't have time to read thatOkay, you don't have time to
read it.
You don't want to believe mebecause everybody says it's a
genetic disease and and theysaid well the whole the whole
hospital system would have tochange Yes, and well, we can't
do that because we're we can'tevery you'll always lie.
We can't we can't we can't no,they're not familiar with the
(42:02):
scientific evidence.
No, they they they they neverheard that glucose drives
dysregulated cell growth theyknow oh no diet can help cancer
just take my radiation and chemoAnd and this is the way
everybody does and they justwalk like sheep You Dozens and
dozens of folks walking likesheep into these institutions.
Yes, a lot of them survive, ofcourse, a lot of them die.
(42:23):
In the United States, we haveover, almost 1, 700 people a day
dying from cancer.
That's 70 people an hour.
It's a worldwide epidemic ofcancer.
And everybody keeps radiationand chemo and surgical
mutilation.
Radiation, chemo, surgicalmutilation, and they do
immunotherapies all based on thesomatic mutation theory.
And if the immuno, if the, ifthe patient doesn't have the
(42:45):
right epitope on the surface ofthe tumor cell, some of those
immunotherapies now rip out yourkidneys and liver and you die a
horrific death from adverseeffects from the immunotherapy.
And they tell us that they'renot hiding this.
When you see the commercials,they spend more time telling you
how, how the therapy will killyou rather than how it's gonna
help you.
I mean, they're not hiding it.
We're all listening.
(43:06):
And then when they get cancer,they all run down and take the
same stuff.
And it's just like, because Imean, so you tell me what's
going on with this picture.
0613 (43:16):
I mean, all I want to do is to, you know, help that one
person.
And we talked about this.
And I mean, if someone islistening right now, who wants
to learn more about this Dr.
Thomas Seyfried, where can theygo and get more information
about this?
squadcaster-a27a_1_06-13-2024 (43:33):
A lot of our papers are, are open
access.
So you just put my name in andsay, what did he publish?
Give me publications.
And you can read it yourself.
So the press pulse metabolic airfor anybody who has a computer
and Google can get the papersthat I've published and then
they read them Oh, wow.
This is really interesting.
How come nobody's talking aboutthis?
(43:55):
And then and it's cited a lottoo.
I it's because the system is soentrenched and so dogmatic and
comfortable in, in what they do.
It's very hard to change theattitudes and the understanding.
I mean, if the NIH is telling usthat cancer is a genetic
disease, and if you look, itsays 100 different diseases.
(44:18):
Yeah.
They have 100 different cancersall with a different name, but
all requiring fermentation togrow.
All those cancers need glucoseand glutamine.
I don't care what you call them.
It's a blood cancer, coloncancer, bladder cancer, five
different kinds of braincancers.
They all ferment.
How do I know that?
Because we did all the studies.
We looked at all the evidence inthe literature and put it all
(44:39):
together in these big papers.
And So if you don't read thepapers, and you, and you can't
understand what I'm saying, thenthe status quo will persist.
It's only when the people getoutraged, and they start beating
the doors down and saying, Iwant metabolic therapy.
And if you can't give it to us,and we're writing a treatment
protocol as we speak.
A really detailed treatmentprotocol for cancer.
(45:00):
We have to publish that.
So we're going to start upsetting up clinics.
We're going to start trainingcertifying physicians to be
certified as a meta, as a personwho can deliver metabolic
therapy.
So they've been trained and,and, and shown what to do and
how to do it.
And now they can go into the,into the communities and set up
clinics treating cancer patientswith metabolic therapy.
(45:20):
So a lot of the parts to do thisare not in place.
We don't have trained physiciansto do this.
A lot of the physicians don'twant to be trained, they want to
know about it.
But once you get certified, thenyou can open up clinics and you
can start treating patients the
0613 (45:34):
But how do we help someone now?
Someone with cancer now?
How do we help them now?
squadcaster-a27a_1_06-13- (45:39):
well, they, they then the, a lot of
the burden falls on them.
And, and I, I give kits out tothe folks that just has
educational information as I,I'm not a physician.
I cannot tell anybody what to door how to do it, but it can only
give them educational materialwith some names of people.
And then they,
0613 (45:57):
Let's do that.
squadcaster-a27a_1_06-13- (45:58):
Like, Yeah, and, and, and they, and
they're, and all I asked them todo is make donations to the
Boston College Cancer Fund on mywebsite or, or to Travis
Christofferson's foundationbecause all of our research is
supported by philanthropy andprivate foundations.
And the more funds that we get,we, the more people we can
train, the more experiments wecan do to convince the skeptics
(46:21):
that cancer is primarily amitochondrial metabolic disease.
So the evidence, the truth.
Just has to build and build andbuild and build so you work on
one side You work the scienceout on the other side you get as
you call them Anecdote afteranecdote fluke after fluke after
fluke after anecdote afteranecdote and it works on dogs,
too It's unbelievable the dogdogs are riddled with cancer And
(46:44):
we have a big paper on, onremoval of a mass, a mass cell
tumor on the face of a pit bull.
And that's published in an openaccess journal.
So, why should the dogs bemanaged and not people?
So, you know, it's, it's, it'sthe whole, the whole thing here.
It's a, it's a work, it's a,it's a momentum that's growing
and growing and growing andeventually will become the
(47:05):
standard of care.
There's no question about itbecause it's based on the
correct theory of what thenature of the disease is.
And when you have the righttheory, Just like the heavens,
we now, we have telescopesrevolving around the earth a
million miles, the webtelescope.
That would have not beenpossible if we considered the
earth as the center of the solarsystem.
It only became clear when theearth was another planet
revolving around the sun andthen the advance in astronomy
(47:27):
and these kinds of fieldsadvance.
Same thing will happen in thecancer field and in the chronic
disease field.
It's just a matter of time.
I have no doubt about it.
It's just that the word, it'sjust the
0613 (47:38):
Yeah.
The policymakers just have to,have to get old.
Right.
So then you come in.
squadcaster-a27a_1_06-13- (47:43):
well, you know, but you know, it's
tragic about that, what I feelabout that, and that's what Max
Planck said, you're, you can'tmove a new field theory forward
until the guys supporting theold theory die off.
But right now we're sacrificing1700 people a day for their, for
their resistance.
I mean, it's not, it's not, youknow, nobody needed to die if
you didn't, if you didn't, ifyou thought the sun of the earth
0613 (48:05):
If we could do it
squadcaster-a27a_1_06-13-202 (48:05):
it wasn't, it didn't.
So, so anyway, this is the,people want to live.
They're going to have torecognize that the cancer is a
mitochondrial metabolicdisorder, and a lot of the
treatment rests on theirshoulder.
But they have to have apractice, they have to have
certified practitioners that canhelp and guide them.
And right now we get you godown, and that's one of the
(48:28):
things that's so tragic.
I tell all these folks, thenthey go down to their, all
excited to go down to theirlocal oncologist and they get
slapped down.
They said there's no evidence tosupport any of this metabolic
stuff, diets don't work, youknow, fasting should never be
done.
I mean, what are they?
And that's only because theylack knowledge.
It's not because they're badpeople.
They just don't know.
(48:48):
Once they know, then they becometotally embarrassed and they
say, Oh, how the hell did we notknow this?
Well, I'm telling you now youshould know it.
And the papers are therepublished and you can read them.
0613 (48:57):
Absolutely.
You know, if if I don't doanother interview, I will be
happy with this interview.
I'm done.
I mean, there, I mean, cancer,again, is such a devastating
word.
You know, we talked about howthe deaths per year that we see,
It's it's such a scary, scaryfor people.
(49:19):
That's why I really want to getto help these people that are
struggling, know somebody that'sstruggling, you know, point them
in the right direction.
Where can people find you?
Maybe connect with you followyou and follow the research.
How, how can they connect withyou?
squadcaster-a27a_1_06-13- (49:33):
Well, I think we've done a lot of
YouTube videos for sure.
So people are starting to hearabout it.
And again, they, they, theyInstagram, you know, there's an
Instagram account.
One of my students, I've gotstudents now doing podcasts in
my, they're, they're actuallydoing some nice podcasts.
You know, it's a, it's a work inprogress.
We're training right now, as wespeak, there's a big conference
(49:54):
going on and in SwitzerlandJosephine Barbarino is, Is
starting to set up a place totrain trained clinicians.
It's a happening event.
It's going to be very exciting.
But I think right now you cansee all the work we've done on
open access.
Just go to look at all mypublications on open access,
become familiar with theevidence, and then start putting
(50:15):
pressure on the health careproviders to say, why are we not
doing metabolic therapy andsupporting the research that we
do and it will eventuallybenefit all of huma all mankind,
everybody, every there's nocountry that has no cancer.
Now there are some actuallyprimitive peoples living
according to their traditionalways, cancer is much less.
(50:36):
They're not, they're not it'sdiet and lifestyle once you
realize that, that are, we'renot getting enough exercise,
we're under stress, we're eatingpoorly, highly processed foods.
All of these impact negativelyon the mitochondria in some
organ and some tissue leading todysregulated cell growth or
obesity or type two diabetes orcardiovascular disease or
(50:57):
hypertension or high blood, allof these things, Alzheimer's
disease.
So again we put them all intothe chronic disease and you're
100 percent correct.
Cancer is a frightening diseaseonly because to treat it you
have to be poisoned, irradiated,and mutilated.
And people don't want that.
They want to know that there'sanother way that we can manage
this without having to sufferlike that.
And they, and if that doesn'tkill you, eventually the cancer
(51:20):
will kill you.
But 50 percent of the people aredying from the treatments rather
than from the disease.
It's a terrible tragedy.
So people have to know, Thatthings can get a lot better once
they understand that can't thenew, the new theory that cancer
is a mitochondrial metabolicdisorder.
0613 (51:37):
You know, even though this podcast, this podcast recording
is, there's a lot of passionhere because we, we believe that
we have to change, you know, thesystem, right.
But there's a, this episode isoffering a lot of hope.
For a lot of people.
And I, I feel like, you know, ifwe can just help that one
person, you know, spread thatword and we're doing the same,
(51:58):
we spread that word, you know,support Dr.
Thomas Seyfried's foundation.
And we'll link everything downin the description box below so
you guys can support Dr.
Seyfried's
squadcaster-a27a_1_06-13- (52:07):
Also, there's one, there's one more
thing.
I wrote only one book.
I never wrote any of thosesummaries.
People should need to know thatsome of those are pirated
things.
They say I wrote them.
I did not write them.
So you have to realize the bookthat you mentioned was the only
book.
It's a, it's, it's not cheap.
It's not 19 or any of thisstuff.
(52:28):
I feel really bad when peoplesay, Oh, I got your, I got your
summary and I didn't, it wasfull of misspellings and it
didn't wasn't clear.
I didn't write that.
I wrote only one book and peopleshould know that.
Because they're all buying theselittle review things that
aren't, that I, that are notwritten in the quality of
writing that I have.
So, it's kind of just, it's kindof just put together.
So yeah, so this is yeah, we'reworking on this and we're not
(52:51):
going to go away any time soon.
And we're going to push it untilthe, until the system changes.
0613 (52:56):
Yeah.
Obviously I'll do the same.
We'll link the book down in thedescription box below so you
guys can, can check it out by,by your book.
Cancer is a metabolic disease.
Is that right?
Let me see.
squadcaster-a27a_1_06-13-2 (53:08):
It's cancer as a, as a, as a
metabolic on the originmanagement
0613 (53:12):
is a metabolic disease.
Yeah.
Yeah, absolutely.
We'll link it down in thedescription box below.
So you guys get that book,
squadcaster-a27a_1_06-13-2 (53:17):
John Wiley, John Wiley Press.
0613 (53:20):
get that copy, get that copy.
Well, thank you so much, Dr.
Thomas C.
Freed for coming on and sharingyour story and sharing your
knowledge here with us today.
I believe that.
We are going to help that oneperson, right?
And if you have a chance tocheck out Dr.
Thomas Seafried's book, go aheadand check it out.
Get your, get your own copy,learn about the metabolic
(53:42):
disease you know, mechanism, youknow, educate yourself about it.
You know, there's nothing betterthan, you know, getting some
more information about this andso you can empower yourself with
that knowledge.
Dr.
Thomas Seafried.
Thank you so much.
squadcaster-a27a_1_06-13-20 (53:58):
Oh, thank you very much.
Nice to be here.
0613 (54:00):
Awesome.
Thank you.
Bye bye.
squadcaster-a27a_1_06-13- (54:02):
Okay.
Take it easy.
Hey guys.
Welcome to the ketones andcoffee podcast.
I'm Lawrence, and I'm sograteful to have you joining me
on this journey.
Every week I bring in guests tohave the knowledge and
experience to help you on yourown journey to a better health.
I'm so excited for this guystoday.
We're We have an honor ofhosting Dr.
Thomas Seyfried, a distinguishedscientist whose groundbreaking
(00:20):
research has reshapedunderstanding of cancer and
metabolic diseases.
Dr.
Seyfried received his Ph.
D.
in genetics and biochemistryfrom the University of Illinois.
Throughout his career, Dr.
Dr.
Siegfried has received numerousaccolades from prestigious
organizations, such as theNational Institute of Health and
(00:41):
the American Society ofNeurochemistry.
His research focuses on geneenvironment interactions related
to complex diseases withsignificant contributions to the
field of epilepsy, autism, braincancer, and neurodegenerative
diseases.
It's an honor, Dr.
Thomas Siegfried.
Welcome to the Ketones Coffeepodcast.
squadcaster-a27a_1_06-13-20 (01:03):
Oh, thank you very much, Lance.
It's very nice to be here today.
0613 (01:06):
is nice to finally grace your presence here on the
podcast.
How are you?
How are things?
What are you excited abouttoday?
squadcaster-a27a_1_06-13- (01:13):
Well, today happens to be a very nice
day.
Very low humidity might get upabout 85.
I'll go over to the gym afterthis, relax do a few things.
And we have a faculty meetingthis afternoon outside.
So that should be interesting.
0613 (01:28):
Very exciting.
Very exciting.
You know, I've had a lot of manyinterviews on my show, but
really I am starstruck bysomeone's presence.
A little hiccup on the beginningthere, but you know, with my
connection issues, but solelysometimes, you know, your impact
on other people's lives.
I mean, the topic we are aboutto discuss today, sir, your own
(01:48):
personal mission, your book.
Cancer as a metabolic disease.
As I was, you know, examiningthe reviews about the book,
countless individuals hasreported life changing effects
and a lot of them say lifesaving.
If anyone of you, someone dearto you is struggling with cancer
(02:11):
or maybe you yourself, thisepisode is for you.
Sir Thomas Seyfried, the wordcancer itself does something to
us that no other word can.
You know, it's, it's one of themost devastating disease known
to man.
The current research tells usthat some of us are genetically
(02:32):
predisposed to developingcancer.
And we all know someone that is,has been affected by this
disease, but you offer a newtheory, one that doesn't need to
be.
Chemotherapy, radiation, evensurgery all at once, right?
And we got a lot to discusshere.
You say cancer is primarily amitochondrial metabolic disease.
(02:57):
That offers hope.
I mean, first of all, what hasled you to the research,
specifically moving away fromthe theory that it's not a
genetic disease, but rather ametabolic disease?
Tell us that story.
squadcaster-a27a_1_06-13- (03:11):
Okay.
So, yeah, well, that's certainlywould be a paradigm change for
sure.
But you have to look at all ofthe facts and evidence, and then
you have to, there's several,several things you well,
required me to know before Icould suggest that the paradigm,
the current paradigm isincorrect and as you said, I
have a degree in genetics andbiochemistry you have to have a,
(03:35):
a foundational understanding ofevolutionary biology, And, and
you have to be familiar with theoriginal work of Otto Warburg.
So, and you need to do theresearch experiments yourself to
test ideas directly in your lab.
You don't rely on what otherssay.
You do the experiments yourselfand you see what the results
(03:56):
happen to be.
And that's what we do.
So, Like everyone, almosteveryone I thought cancer was a
genetic disease.
I mean, we had this in all ofour research lectures that we
get whether they're departmentalseminars, whether in the
textbooks of biology, cellbiology or biochemistry, you can
(04:16):
pick up any one of them andthey'll say that cancer is a
genetic disease.
And then of course, on theNational Cancer Institute
website at the NIH.
It says cancer is a geneticdisease.
Who am I to question, toquestion the prevailing view the
dogma the silent assumption.
But I, I started seriouslyquestioning that when I started
(04:39):
to see research in my own labthat treating animals that have
tumors with calorie restricteddiets cause significant
reduction.
in the rate of growth theinflammation around the tumor
and many other and the increaseddeath of tumor cells.
And it, and we, we, we, welinked that to a reduction in
(05:02):
blood glucose levels.
And I thought this was a greatobservation.
And then I realized that OttoWarburg had made similar
suggestions in the 1920s and30s, publishing a seminal review
paper in 1956, clearly sayingthat cancer was a metabolic
problem, not a genetic problem.
(05:23):
Problem is the field thatalready spent billions of
dollars hunting for genes incancer.
And there's no question thatmany, many, most cancer cells
have genetic mutations.
We're not, this is a fact.
Cancer cells, most of them havegenetic mutations.
But the question is, are thosemutations responsible for the
dysregulated cell growth, or isit some problem with energy
(05:46):
metabolism.
And of course the geneticistssay the, the abnormal energy
metabolism is caused by the genemutations.
On the other hand, that's hardto understand how gene mutations
could actually influence theamount of ATP energy within the
cell, because that was amitochondrial driven process.
So it turns out that you know, Istarted to look at this and do a
(06:10):
deep dive on Warburg's theory.
And it turns out that Warburgsaid all cancers initiate from
an insufficiency of oxidativephosphorylation linked or
coupled to a compensatory energythrough substrate, or I should
say fermentation.
Fermentation is energy withoutoxygen.
So, and, and we know this,everybody knows this.
(06:33):
So, okay, we have gene mutationsand we have tumor cells arising
or can live without oxygen.
And, you know, it's veryinteresting.
I always tell everybody this.
If you take cyanide, you know,it's cyanide, it's a very toxic
poison.
Cyanide kills people veryquickly, animals, any, any, any
organism.
That's using oxidativephosphorylation, breathing air
(06:56):
to get energy cyanide blocksthat and shuts it down and, and
will kill very, very quickly.
Can Warburg said a long timeago, and we validated what he
said.
Cancer cells live in cyanide,can live in the presence of
cyanide.
That tells me right there,they're not using oxygen for
energy and they also grow in theabsence of oxygen.
This is hypoxia.
So cancer cells, well, how arethey growing and living?
(07:18):
without using oxygen as a sourceof like we breathe oxygen and,
and we generate energy.
We exhale CO2, the breakdownproducts.
These damn cancer cells are,are, are living without, without
oxygen.
That's very interesting.
So, and it turns out Warburgsaid because their mitochondria
are defective and people say, Ohno, Warburg was wrong.
(07:40):
Most of the field says becausecancer cells consume oxygen
also.
But the problem with the cancercells, they're taking, consuming
oxygen, but they're not using itfor energy.
This is what, what we foundwhich then throws a stick in the
spoke of the field.
And then we went back and wefound some papers saying they
can't find any mutations in somecancer cells.
(08:01):
Well, that, that's notconsistent with the somatic
mutation theory of cancer.
So then they said, The field, ofcourse, says, Oh, well, not all
mutations are causing cancer.
Only the driver mutations causecancer.
These are the really importantones.
So new research now is tellingus that we have driver mutations
and all through our body thatnever, in cells that never form
(08:22):
cancer.
So that's inconsistent againwith the theory.
Every major cancer we've lookedat has damage in number,
structure and function ofmitochondria.
That seems to be thecommonality.
And then you say, well, wheredid all these mutations come
from?
And the answer is when oxygencomes into a tumor cell, not
using it for energy.
They form reactive oxygenspecies called, these are
(08:44):
reactive radicals and theydamage DNA, RNA, and proteins.
So the mutations that we see incancer cells that the field is
constantly targeting or lookingat are all downstream effects.
So, We spent billions andbillions of dollars in the
cancer genome projects with thehope that we would find
(09:05):
mutations Causing dysregulatedgrowth and we could target those
mutations and therefore bring anew realm to cancer management
Well that has been a almostcomplete failure It hasn't
worked.
So consequently We persist intreating cancer patients with
toxic poisonous chemicals,radiation, and surgical
(09:25):
mutilation, because the promiseof the genomic theory, the
somatic mutation theory beingfinding targeted mutation has
not come to pass.
And that's because cancer is nota genetic disease.
It's a mitochondrial metabolic.
What does that mean?
All cancer cells must get energyfrom.
fermentation, which is energywithout oxygen.
(09:46):
So the question then, what dothey, what's driving this
fermentation energy?
And we and others have foundit's glucose and glutamine.
The sugar glucose and the aminoacid glutamine are both
fermented to generate ATP energyfor the dysregulated growth.
And they can't burn fatty acidsor ketone bodies.
Cancer cells cannot live onfatty acids or ketone bodies in
(10:10):
the absence of glucose andglutamine.
So that tells us clearly how tomanage cancer without toxicity.
Problem is the rest of the worldhas not opened their eyes or
understood what I have just
0613 (10:20):
Simple.
You've, you've explained that tome within five minutes and I, I
could understand it.
It's, it's simple and there'sevidence there, and it is you,
you know, I feel like theinconsistency you found in the
research drove you to seekinganswers.
But I wanna know why were youexamining.
(10:42):
Caloric restrictions versus theprogression of cancer or the
growth of cancer.
What, what, what initiated that?
Glutamine.
squadcaster-a27a_1_06-13 (10:50):
found, we worked in the field of
epilepsy for years and we knewand we knew that ketogenic
restricted ketogenic, I was, Ishowed, the folks that the
ketogenic diet was working andkill and Children predominantly
because it was lowering bloodsugar.
And when we were lowering andthe kids would eat ketogenic
diets and their epilepsy wouldgo away, why did the epilepsy go
(11:11):
away?
And the answer is because wereduced blood sugar and elevated
ketones.
And you can see a child thatmight be managed without having.
seizures will drink a glass ofsweet orange juice or something
like that, and within within 30minutes, they'll explode into an
epileptic seizure and theirblood sugar shoots up and then
they explode into an epilepticseizure.
(11:32):
So it was clear to us that themanagement of epileptic Epilepsy
in children using theseketogenic diets was related to
the lowering of glucose and theelevation of ketones.
But the mechanism in the brainby which lowering glucose and
elevating ketones blockselectrical excitability in parts
of the brain.
The, the, the molecularmechanisms for that are still
not completely known.
(11:53):
However, the cancer.
We know exactly what's going on.
Very close to the understandingmore completely than, than
epilepsy for sure.
When you lower the blood sugar,cancer cells need fermentable
fuels.
Glucose is a prime fermentablefuel.
And therefore you're shuttingdown one part of their energy
metabolism.
The other part, which wasn'tclear, at the beginning to us
(12:15):
how that was working wasfermentation of the amino acid
glutamine and Warburg knewnothing about that either.
And therefore he ran into a lotof controversy and a lot of
misunderstanding because hecouldn't figure out where some
of these cancer cells, eventhough your lower blood sugar
really low, they were stillhanging on and still growing.
Why, where are they gettingtheir energy from?
(12:36):
And he didn't know about theglutamine issue.
And now we were the oneseverybody knew glutamine.
They all thought it wasrespired.
We're now showing that theglutamine is fermented, which
means getting glutamine, theenergy out of glutamine without
oxygen.
That's the big breakthrough inthe cancer field, as far as I
can see which Warburg did notknow about.
And right now the 90, 95 or 99percent of the cancer field also
(12:59):
cannot understand that theyeither can't understand it or
they can't believe it.
Yet we have evidence now, wejust published a major paper on
this, and my, my colleagueChristos Xenopoulos from
Semmelweis University, he hasdocumented this in cancer cells.
So we have clearly now, we knowhow cancer cells are getting
energy for the dysregulatedgrowth.
So all we have to do is targetthe availability of the energy
(13:22):
and you can shut down thesetumor cells for the most part.
0613 (13:24):
We'll talk about glutamine there in a second.
I want to break this down forour listeners here.
I want to talk about metabolic,this metabolic theory that we
have here.
Obviously there's a lot ofevidence showing that you know,
showing a lot of promise.
A lot of people are talkingabout how you know, this.
is a life changingtransformation, right?
Just, just reading your book,Cancer as a Metabolic Disease,
(13:47):
you outlined the data on thatbook from 2013, 2017, the
percentage increase for cancerdeaths is greater than the
increase for newer cases.
And you call it a failure of, ofmonumental proportions.
I mean, something is off.
And, and You, you found a wayto, to finally you know, seek
(14:11):
answers and, you know, basicallyyou're seeing we're losing the
war and your research showsthat, that there is a
fundamental misunderstanding ofwhat the nature of the disease
is.
Right.
And you're basically saying wegot it all wrong.
What cancer really originatesfrom and what can be argued
about it is being the reason whyit's only getting worse.
(14:32):
But I wanted to ask you, how didthey get it wrong?
If the research seems conclusiveof the evidence, that is, it's a
genetic disease, right?
It's when you read the researchpapers, it seems very
conclusive, right?
What made you challenge theconventional wisdom there?
I know we talked about youstarting from, you know, your
(14:55):
studies with epilepsy, right?
And, and, and you connected thatto how our understanding of
where cancer originates from.
Did they get it or wrong?
I, I wanna, I wanna know theirperspective and how are they not
open to this idea?
Mm-Hmm.
squadcaster-a27a_1_06-13- (15:14):
Well, those are very important
questions.
And they go to the core ofscience of how science advances.
And I look at it very similar tothe Copernican revolution.
When for 1800 years scientistsand astronomers thought that the
earth was the center of the, ofthe solar system.
(15:36):
The work of Aristotle andPtolemy and other astronomers at
that time could not completelyexplain how planets and
celestial bodies, their, their,their motion through the heavens
was always challenged.
And the field and the systems.
Kept doing more and more studiesto try to better, better
(15:59):
calculate how, how heavenlybodies were moving.
But there was always someproblem that could not explain
clearly how everything wasmoving.
But they persisted and persistedand persisted for 1800 years in
doing these experiments thatwere never able to completely
define this until untilCopernicus realized that if we,
(16:20):
if the earth is in fact movingand travels around the sun
together with the other planets,you could actually explain the
mathematics and you couldexplain the movement.
We're in a very similarsituation here with cancer.
The field has becomeindoctrinated and dogmatic in,
and believing that, thatmutations are the origin of the
(16:40):
dysregulated cell growth.
The strongest evidence to saythat cannot be the case is the
nuclear mitochondrial transferexperiments, which I've
published in my book.
And I wrote a paper on thisspecifically showing the field
that if you take the nucleus outof a tumor cell.
that has all the mutations inthe nucleus that are supposed to
(17:01):
drive the dysregulated growth,and you transplant that nucleus
into a, into a non cancerouscytoplasm containing normal
mitochondria, the, the results,the offspring, of those cells
have normal growth.
They don't have dysregulatedgrowth, even though the
mutations in the nucleus stillthere are there.
(17:22):
On the other hand, if you, ifyou take the normal, the nucleus
from a normal cell andtransplanted to a cytoplasm, a
tumor cell cytoplasm withabnormal mitochondria, the
offspring of those, is isneoplastic dysregulated cell
growth.
So clearly the origin ofdysregulated cell growth resides
in the cytoplasm with themitochondria, not in the nucleus
(17:44):
with the genetic mutations.
That's the strongest evidence.
That's the same power of, ofCopernicus putting putting the
sun in the center of the solarsystem.
It's, it's, it's that powerful.
Now, of course, what happenedwhen Copernicus did that?
Galileo immediately started touse the telescope to confirm
Copernicus's theory and washouse arrested.
(18:07):
Giordano Bruno an Italianscientist was burned at the
stake for challenging theCatholic Church's dominance over
what we should think and what weshould know getting back.
So how is it possible that thecancer field, a multi billion
dollar industry, fails torecognize the that their efforts
to manage cancer is incompletebecause they think it's a
(18:30):
genetic disease.
They're locked into the samedogmatic view.
How could they all be wrong?
Confirmation bias says they notbe wrong.
If they, if the federalgovernments of the United
States, Canada, Germany, Japan,England, all of these guys are
saying cancer is a geneticdisease.
Who the hell am I to come andchallenge them?
(18:50):
All I did was look at the data.
I let them disprove what I'msaying.
It's not me.
They have to try to disprove theevidence that's clearly shows
that cancer cannot be a geneticdisease.
Yes, cancer cells havemutations.
We all know that, but they arenot the cause.
They're the effect of the damageto the respiration.
So once you realize, then youcan move forward.
(19:13):
with therapies and treatmentsthat are non toxic and
powerfully effective to manageit.
Because you're now doing what,they can't live without
fermentation fuels.
That's the, they can't livewithout that.
So you just have to target that.
And there's no clinical trials,there's no treatment programs or
any of this that's testing whatI'm saying.
(19:35):
Because who's going to testthis, the pharmaceutical
companies that are makingbillions of dollars on drugs
based on the somatic mutationtheory, all those
immunotherapies, who's going totest this?
The hospitals, they're lockedinto making great revenue from
radiation and chemo and all thisother stuff.
Who wants to test a theory thatcould potentially reduce revenue
(19:57):
generation for the majority ofthese institutions, grants to
the, to the scientists from thethe, so what we're saying.
So you have to, what we did,what people do in the past is
you ignore what I'm saying.
That's the easiest thing.
And the simple, oh, it hasn'tbeen repeated.
It has been repeated numeroustimes.
You should choose not to look atthe data.
Oh, and no clinical trials.
(20:17):
Oh, why don't you do a clinicaltrial after you train, train the
folks?
Oh, we can't do that.
Everything is, we can't, wecan't.
We can't, we can't, okay?
So when you get the deniers, andthe so news sayers, and all
those other guys out of the way,those guys just gotta out of the
way, let us move forward andwe'll be able to I'm not saying
we can cure cancer, all I'msaying is we can provide an
(20:38):
outcome far superior to whatpeople are currently
experiencing today.
0613 (20:43):
And it's, and, and since you've compared it to, you know,
18 hundreds you know, research,it's bound to change.
Right.
And you alluded to the fact thatit is, it, it all comes back to
the lack of knowledge on thebiology of the disease.
Right.
From your,
squadcaster-a27a_1_06-13- (21:00):
Well, it's not that they have a lack
of knowledge.
These guys are well educatedfolks.
They're very smart.
They just are working under anincorrect theory, okay?
That's the key.
It's the theory that drives theunderstanding of the biology.
If the theory says that canceris a genetic disease, you're
focusing on gene mutations.
(21:22):
You're not focusing onmitochondrial insufficiency of
oxidative phosphorylation or thedependency of those cells on the
two fuels.
And when I tell folks that, whydon't you take away the glucose
and glutamine in the media thatyou're studying?
They say, we can't do thatbecause the cancer cells will
all die.
And I said, yeah, that's the,that's the, that's the whole
thing.
You won't have anything to studyif you take away the two fuels
(21:43):
that drive the dysregulatedgrowth.
Now you have to play this inthe, in the living system, of
course.
And we've worked out the presspulse therapeutic strategy,
which adopts that concept totreating cancer patients.
So, and it's working on the, onthe people that are doing it in
the isolated places where theydo it.
Most of them, not all of them,most of them get do much better.
(22:05):
The cancer goes either becomesmuch reduced in rate of growth
or it goes into some sort ofstabilized state and sometimes
might go away at least for the,the, the, the short term.
But we've, people are there.
I don't know how many yearsPablo Kelly's out 10 years now.
His cancer never went away.
a brain tumor.
He's had three surgeries on aglioblastoma, but he's still
(22:27):
alive.
You know, you don't usually livebut a, a year or two with that.
And he's out 10 years now.
So did it, was he cured now?
Is he living a hell of a lotlonger than everybody else?
You're damn right.
He is.
0613 (22:39):
And it's a classic, they're not looking in the right
place.
Right.
From your research on the canceras a metabolic disease, in your
view of this disease, where itoriginates as a metabolic
dysfunction, how does that leadto the development and
progression of cancer nowstarting as a metabolic
(22:59):
dysfunction, where, where doesthat, Now we've identified where
it's actually originating, buthow does that lead to the
development of cancer?
squadcaster-a27a_1_06-13- (23:09):
Yeah.
So let's look at the theprovocative agents that we all
know are car, are carcinogenic,the term chemical carcinogen.
Why do they call a chemical acarcinogen?
Because it causes cancer.
Okay.
Asbestos.
And we found you know, varioustetra, these various chemicals,
you know, we have, we call themcarcinogens.
(23:29):
So I went through all the listof carcinogens and every one of
them damages the structure andfunction of the mitochondria,
the organelle responsible forgenerating energy through
oxygen.
So In the case of a carcinogen,what happens is the energy
coming out of the mitochondriais compromised.
And in order for the cell tostay alive, it has to compensate
(23:51):
with upregulation of substratelevel phosphorylation, which is
an alternative source tooxidative phosphorylation.
I don't want to get toocomplicated on this.
It's just a fermentationmetabolism.
Okay.
Now what is What controls thedifferentiated quiescent state?
Suppose, suppose you have yourliver, for example we'll use
(24:13):
that as an organ and it'sexposed to chemical carcinogen.
And all of a sudden you see apopulation of cells growing out
of control in the liver.
What, what caused those normalliver cuboidal cells,
hepatocytes, let's say, to grow?
to start growing out of control.
So when you look at them, youfind that the mitochondria are
(24:34):
dysfunctional and damaged andthey're fermenting.
Okay.
How did that happen?
How did the chemical carcinogencause a bunch of cells in the
liver to start growing out ofcontrol?
So what is the organelle thatcontrols the stable and
differentiated state?
And it's the mitochondria.
The mitochondria control thecell cycle.
So the normal a metabolicallystable homeostatic state of the
(24:58):
cell is controlled by themitochondria.
That organelle controls the cellcycle.
Now, when that organelle becomescorrupted, the cell falls back
on a fermentation mechanism,fermentation.
Now you have to realize this iswhy you need to know
evolutionary biology.
Before oxygen came into the,onto the atmosphere of our
planet was completely a noxious.
There was no oxygen in theoriginal beginning earth of the
(25:20):
earth two, two and a halfbillion years ago, two and a
half billion years ago, we hadcells that were developed that
were growing on the planet.
Some of these organisms, single,single cell organisms, everybody
was fermenting.
All those cells were fermentingand they were growing in a
dysregulated way dysregulatedcell growth with a fermentation
metabolism.
(25:40):
The cancer cell.
is going back and expressing thesame characteristics as these
original cells that existed on afermentation.
Why are they growing out ofcontrol?
Because the organelle that'ssupposed to control their growth
now is dysfunctional and thecells fall back on these ancient
pathways of fermentation.
And when you look at cancer,every major cancer is throwing
(26:00):
out massive amounts of lacticacid and succinic acid, the
waste products of a fermentationmetabolism becomes clear.
So these cells are doing nothingmore than falling back on
ancient metabolic pathways thatexisted before oxygen came into
the atmosphere.
These pathways exist in all ofour cells, but they're very
subdued.
They don't play a big rolebecause we're breathing air.
(26:21):
But but when we stop, when we,when our mitochondria become
chronically damaged, not acutelydamaged, acutely damaged, the
cell will die.
You'll never get a cancer cell.
But if it, but if the cell hasthe opportunity to upregulate
fermentation, it loses growthcontrol and starts growing out
of control.
Now that's chemical carcinogen.
What about oncogenic viruseslike hepatitis virus,
papillomaviruses?
(26:42):
They do the same thing.
They chronically damagemitochondria.
What about radiation?
Radiation we know can causecancer.
Well, that chronically damagesmitochondria.
What about intermittent hypoxia?
What about these things.
What about the BRCA1?
What about those written geneticrisk factors that we hear about?
P53, BRCA1.
These are inherited riskfactors, right?
(27:02):
So they damage the structure andfunction of the mitochondria
leading to dysregulated cellgrowth either in the breast or
some other organ, right?
The liver h Uh, BRCA1 can be thebreast cancer mutations that you
hear about, but they damagemitochondria.
If the BRCA1 doesn't damagemitochondria, that, that person
can have the mutation and neverdevelop, never develop the
cancer.
(27:22):
It only happens when themitochondria develop.
Cancer is very unlikely to occurif the mitochondria can remain
functional and, and normal.
Let's put it that way.
So, normal, normal generation ofenergy through oxidative
phosphorylation is normalfunctioning mitochondria.
When that becomes compromised,they start to ferment and they
(27:43):
lose their control, their growthcontrol, and they grow out of
control.
And what's the energy?
It's a fermentation energy.
What do you mean?
They're using, they're usingancient pathways.
Well, what's driving thoseancient pathways?
Glucose and glutamine.
How do you know?
Because we tested it all, weinterrogated all the other
fuels, and glucose and glutamineare the two prime fuels that are
responsible for the dysregulatedgrowth.
(28:04):
Why?
Because the mitochondria are nolonger functional, so therefore
they must ferment.
So this is, and so you feed themketones and feed them fatty
acids, they can't use ketones infatty acids.
Why?
Because these fuels are non,they can't be used for
fermentation.
They're non fermentable fuels.
But the normal cells in the bodycan.
can burn ketones and fattyacids.
(28:25):
So we just transition the wholebody.
to ketones and fatty acids,tumor cells can't use them, and
then you come in and you targetthe glucose and glutamine
simultaneously and startslaughtering these tumor cells
without toxicity.
How does that sound?
0613 (28:39):
Good.
I mean, two more cells cannotuse ketones, right?
But are actually preferred bythe healthy cells.
So you're killing off cancersand healing the body at the same
time, basically.
squadcaster-a27a_1_06-13 (28:51):
That's right.
That's right.
And when you use metabolicketogenic metabolic therapies
you not only get rid of we, thepeople that we see oftentimes
have type two diabetes, they'reobese, they have all kinds of
other hypertension and all thiskind of stuff.
A lot of that stuff goes away.
along with the cancer becausethey're all suffering from a
chronic problem, the chronicenergy disruption.
(29:12):
And in some kinds that causesdysregulated cell growth.
Other times it causes type twodiabetes, hypertension, all
these cardiovascular diseasedementia.
It's unbelievable.
So as long as you can keep yourmitochondria healthy you can
avoid a lot of the chronicdiseases.
The pro the problem is our dietand lifestyle today.
Often stand in the way is anobstacle to prevent us from
(29:32):
getting cancer in the firstplace.
So, we, we, but you know, mostpeople want to know, what are
you going to do for me after Iget the tumor?
I know I should have been a goodboy and a good girl and I should
have never done what I did, butI got cancer.
Now, what are you going to dofor me now?
We have to target the glucoseand glutamine and transition
your whole body off totherapeutic ketosis.
0613 (29:49):
Yeah.
Yeah.
So that that's, so you're sayinglike cancer feeds on glucose,
right?
The idea which is one of thereasons why extended fasting has
become so popular with cancerpatients as an alternative
treatment to how about, howabout DNA mutation?
How does that fit in the, in thetheory?
squadcaster-a27a_1_06-13- (30:08):
Yeah.
Well, when the when the cancer,if the mitochondria become
defective and they take inoxygen, the oxygen forms rat
Ross reactive oxygen species.
These are hydroxide ions superoxides.
These are damaging radicals.
They cause the mutations in theDNA.
So the mutations in the DNA,what is the provocative agent
(30:29):
causing the mutations in theDNA?
And that's ROS.
ROS are carcinogenic andmutagenic.
Hundreds and hundreds of papersin the scientific literature
showing that ROS, R O S, arecarcinogenic and mutagenic.
Okay?
Carcinogenic and mutagenic.
So where, and that produce,where do they produce?
They produce in damagedrespiration, damaged
mitochondria.
(30:50):
Disfunction of mitochondria thatare insufficient in oxidative
phosphorylation form these RAS.
The RAS then damage the DNAcausing the mutations that
everybody's all excited to seeand chase.
But they're all downstreameffects of the damage to the
oxidative phosphorylation.
So, so, and how are the cellsgrowing?
They're growing like crazy withall these DNA mutations.
So, so what's driving thereanyway?
(31:12):
How are they growing with allthese mutations?
Because they're fermenting.
What are they fermenting?
Glucose and glutamine.
Why don't we take away theglucose and glutamine and we can
kill the cell regardless of themutations they have in the
nucleus.
And that's exactly what we see.
0613 (31:23):
Okay.
So we know how to take awayglucose.
How do we take away glutamine?
squadcaster-a27a_1_06-13-202 (31:27):
We have to use, we have to be very
strategic.
Because glutamine is, is, isconsidered a non essential amino
acid, but for the cancer cell inthe immune system, it's an
essential amino acid.
Yes.
So you have to be strategic.
Dosage, timing, and schedule.
You can't go in there as anignoramus, as a bull in a china
shop and just try to take awayeverybody's glutamine.
(31:48):
You strategically target it andthen pull off.
Target and pull off while youkeep the choke hold on the
glucose.
We don't need glucose glucose,but we can replace glucose with
ketone bodies There was aninteresting study some years ago
by by the scientist Drenic.
He took morbidly obese guys Andhe fasted them for 21 days Where
(32:08):
their blood sugar went down andtheir ketones went way up And
then he injected them withinsulin.
Can you believe this?
So whatever little glucose wasin their bloodstream, it kind of
disappeared.
It went down to nine milligramsper decaliter, which everybody
would consider death.
0.
5 millimole.
I mean, this is like barelydetectable.
These guys are walking aroundfine.
(32:29):
No cognitive decline noabnormalities.
And, and, and it was because thebrain and the rest of the cells
switched over to fatty acids andketone brain burns, fatty ketone
bodies, liver can burn fattyacids.
So it shows you how low you canget glucose.
And then the normal cells ofyour body will take up what
little glucose might beavailable, starving, indirectly
(32:52):
starving the cancer cell of itsglucose.
And that, but it can still hangon because it might suck down a
little bit and ferment a littlebit of the glutamine.
So then you just pulse theglutamine with glutamine drugs
and some of these drugs areparasites Antiparasite drugs
turns out that the cancer cellsand the parasites use a common
metabolic pathway So if you killparasites, you can kill cancer
cells with the same drug.
(33:12):
It's not this stuff isunbelievable I mean if the field
knew what I just said we wouldbe dropping the death rate of
these cancer patientsSignificantly within a very
short period of time.
The problem is what I just toldyou either doesn't want to be
recognized, it's toocomplicated, or I don't want to
know about it.
You know who wants to know aboutwhat I'm saying?
(33:34):
The cancer patients want to knowwhat I'm saying.
But you go to the oncologistsand they have never heard of
anything that I had just said,and many of them don't even want
to know about it.
They think glucose has no rolein cancer.
They think fasting has no rolein cancer.
Never heard of glutamine issue.
They, they say, oh no, eatinfomel, eat candy and all this
kind of stuff.
I mean, this tells you how farout of, out of, out of, out of
(33:57):
touch The oncology community isand these are good folks.
They've just been they've justbeen trained the wrong way They
want to help their patients nothurt their patients, but they've
just Haven't had thisinformation in their training
and once they do we're going tosee a monster change very rapid
change in the outcome
0613 (34:15):
I mean, you did call it the future of cancer treatment.
squadcaster-a27a_1_06-13-20 (34:20):
Oh, absolutely Absolutely.
It will be the new standard ofcare.
It's just, it's just has to beunderstood.
And your job is to sometimesthese podcasts push the
information out where, wherewill the change come?
That's the question.
The change must come from the,from the patients themselves.
The change must come from thepopulation of people.
(34:43):
that suffer the greatest fromthis.
It's not going to come, I don'tthink, from the top medical
schools or the pharmaceuticalindustry because they have too
much, they're comfortable,they're very comfortable in
their current status.
And I get calls from dozens anddozens of physicians who
actually get cancer.
and they're stage four.
They're, they're coming to me toget information on how to manage
(35:06):
their cancer because radiationand chemo and surgical
mutilations, they, theycertainly can help some people.
But even if you survive that youpay a significant price, your
body has been poisoned andradiated and mutilated.
And your quality of life is, youknow, sometimes not always
optimal after surviving toxictreatments, whereas metabolic
(35:29):
therapy can eliminate a lot ofthat.
And the other thing you have torealize we don't throw out all
the standards of care.
We're finding that thesechemicals, these chemotherapies,
maybe even immunotherapies andradiation therapy have a much
greater therapeutic benefitwhen, when the patient is in
nutritional ketosis.
So even getting the patientinto, not only will the patient
(35:51):
start killing their tumor cells,they'll be much more responsive
to the chemicals and treatmentsof the standard of care.
So it's going to be a hybridtransformation as we move from,
from, from an incorrect theoryto the correct theory of what
the disorder actually is.
0613 (36:06):
so what does that look like?
A hybrid treatment.
So we combine the drugs thattarget glutamine and then a
ketogenic therapy, whicheliminates
squadcaster-a27a_1_06-13- (36:14):
Yeah, yeah.
What we do is we bring patientsin and we do a comprehensive
blood work.
We find out how, how close orfar they are from optimal
physiological state, what wecall optimal metabolic state.
We have to bring that patientback into some level of
metabolic homeostasis.
And once they're in thismetabolic, and that could be
(36:34):
eating Zero carb diets for aweek or two.
You can start to see the, theglucose go down, the ketones go
up, the patient generally getshealthier.
Then you bring in either sta mestandards of care some chemicals
that are currently being used,or you can use small dose of
radiation depending on the typeof tumor that it is.
Everything responds better whenthe patient is in nutritional
(36:55):
ketosis.
And then you can bring in theglutamine targeting drugs.
And that has to be.
Known.
We, we, dosage timing andscheduling have to be optimized.
And that's what we're doing herein my lab is we're optimizing
dosage timing and scheduling forthe different diet drug combos,
which will eventually be thestandard of care.
Patients are going to have toknow this.
There's no pill.
(37:16):
that will be able to do whatmetabolic therapy can do, but a
pill can work remarkably wellwith metabolic therapy.
So it has to be a combinationbecause don't forget it took a
long time for that person to gofrom a state of health to ill
health and having cancer.
So you're, you're to, to, toturn that whole system around
requires some effort on the partof the patient.
(37:36):
So the patients themselves haveto play a role.
a significant role in thetransformation of their body
from ill health to health.
So they, in order to havesuccess, the patient must play a
significant role in thisprocess.
They're no longer sitting thereas bystanders for being treated
with chemicals and radiation.
With metabolic therapy, a largepart of the success depends on
(37:59):
the motivation of the patient.
0613 (38:01):
That's right.
That's right.
So there are a lot oftestimonials from countless.
You know, success stories, andyou, you already alluded to one,
any specific success storiesanother success story that come
in mind you might share with ustoday.
squadcaster-a27a_1_06-13- (38:20):
Well, we have Maggie Jones who's
writing the cancer revolution.
Doctor got documentary.
They're producing a professionaldocumentary.
Brad Jones, the husband, Brad isa professional movie maker in
the documentary field, andthey're collecting dozens and
dozens of for terminal cancerpatients and having every one of
(38:42):
those stories told by the, bythose patients.
And you know, all of them in oneway or another lowered glucose
and elevated ketones.
And then they did a variety ofother things with certain
supplements that work togetherother dietary things.
So they're collecting all ofthe, all of these testimonials,
if you will, and anecdotes.
And there's and we have to havetrained, but you can't start
(39:05):
doing large clinical trialswithout having a knowledgeable
practitioner running the trial.
And so, so right now we're justcollecting person after person,
after person, after person, andthey have brain cancer, colon
cancer, lung cancer, breastcancer pancreatic cancer.
We've written on that prostatecancer, bladder cancer
(39:26):
melanomas.
blood cancer, the whole range ofblood cancers.
We're, we're, we're seeing thesame overall outcome with a
variety of cancers because,because all major cancers have
to rely on fermentation forgrowth.
So the same therapeutic strategyis effective against all the
major cancers because all majorcancers are similar.
(39:46):
They need fermentation forgrowth.
And we, and how do we know that?
I, I published a major papershowing that all major cancers
have abnormalities in the numberstructure and function of the
mitochondria.
That means they all have toferment.
Therefore, they're all dependenton glucose and glutamine to some
extent.
So this then becomes a clearstrategy for moving the entire
field forward in the correctdirection, because it's based on
(40:09):
the correct theory of what thenature of the disease is.
0613 (40:12):
I mean, with this type of promise, and we're seeing a lot
of results here, it's not a warbetween science and cancer.
I think it's more of the medicalcommunity accepting the shift
away from conventional toxictreatments towards metabolic
therapies.
Would you agree?
It's I think it's, it's, it'smore, more that than just
(40:35):
cancer.
I mean, if, if we're seeing alot of great results with
individuals with cancer even inlater stages of cancer, get you
know, reversing or even, youknow, healing from that.
Isn't that the war is just, ifthey just accept a lot of people
(40:56):
will be saved.
Like, that's what I feel.
squadcaster-a27a_1_06-13-20 (41:00):
No, you're 100 percent correct.
So now, here's a, here's a achore for you.
Go, you're in Toronto, okay?
They have a large cancer centerin Toronto.
Why don't you go down and askthe guys there, how come you're
not doing metabolic therapy?
And you'll get, there's noevidence to support that.
Well, did they read thescientific literature showing
(41:20):
all the detailed experimentalexperiments that.
We and others have done tosupport that.
No, I haven't read it.
Well, what makes you say thatthere's no evidence to support
it?
Because if it's people will theysay well If it was really
important, I would have heardabout it.
Well, you are hearing about it.
You're doing nothing about it Imean, it's just i'm telling you
about it
0613 (41:39):
Okay.
squadcaster-a27a_1_06-13-20 (41:40):
And yeah, well, I don't believe you
okay, he doesn't believe meWell, did you read the
scientific evidence to supportnow?
I don't have time to read thatOkay, you don't have time to
read it.
You don't want to believe mebecause everybody says it's a
genetic disease and and theysaid well the whole the whole
hospital system would have tochange Yes, and well, we can't
do that because we're we can'tevery you'll always lie.
We can't we can't we can't no,they're not familiar with the
(42:02):
scientific evidence.
No, they they they they neverheard that glucose drives
dysregulated cell growth theyknow oh no diet can help cancer
just take my radiation and chemoAnd and this is the way
everybody does and they justwalk like sheep You Dozens and
dozens of folks walking likesheep into these institutions.
Yes, a lot of them survive, ofcourse, a lot of them die.
(42:23):
In the United States, we haveover, almost 1, 700 people a day
dying from cancer.
That's 70 people an hour.
It's a worldwide epidemic ofcancer.
And everybody keeps radiationand chemo and surgical
mutilation.
Radiation, chemo, surgicalmutilation, and they do
immunotherapies all based on thesomatic mutation theory.
And if the immuno, if the, ifthe patient doesn't have the
(42:45):
right epitope on the surface ofthe tumor cell, some of those
immunotherapies now rip out yourkidneys and liver and you die a
horrific death from adverseeffects from the immunotherapy.
And they tell us that they'renot hiding this.
When you see the commercials,they spend more time telling you
how, how the therapy will killyou rather than how it's gonna
help you.
I mean, they're not hiding it.
We're all listening.
(43:06):
And then when they get cancer,they all run down and take the
same stuff.
And it's just like, because Imean, so you tell me what's
going on with this picture.
0613 (43:16):
I mean, all I want to do is to, you know, help that one
person.
And we talked about this.
And I mean, if someone islistening right now, who wants
to learn more about this Dr.
Thomas Seyfried, where can theygo and get more information
about this?
squadcaster-a27a_1_06-13-2024 (43:33):
A lot of our papers are, are open
access.
So you just put my name in andsay, what did he publish?
Give me publications.
And you can read it yourself.
So the press pulse metabolic airfor anybody who has a computer
and Google can get the papersthat I've published and then
they read them Oh, wow.
This is really interesting.
How come nobody's talking aboutthis?
(43:55):
And then and it's cited a lottoo.
I it's because the system is soentrenched and so dogmatic and
comfortable in, in what they do.
It's very hard to change theattitudes and the understanding.
I mean, if the NIH is telling usthat cancer is a genetic
disease, and if you look, itsays 100 different diseases.
(44:18):
Yeah.
They have 100 different cancersall with a different name, but
all requiring fermentation togrow.
All those cancers need glucoseand glutamine.
I don't care what you call them.
It's a blood cancer, coloncancer, bladder cancer, five
different kinds of braincancers.
They all ferment.
How do I know that?
Because we did all the studies.
We looked at all the evidence inthe literature and put it all
(44:39):
together in these big papers.
And So if you don't read thepapers, and you, and you can't
understand what I'm saying, thenthe status quo will persist.
It's only when the people getoutraged, and they start beating
the doors down and saying, Iwant metabolic therapy.
And if you can't give it to us,and we're writing a treatment
protocol as we speak.
A really detailed treatmentprotocol for cancer.
(45:00):
We have to publish that.
So we're going to start upsetting up clinics.
We're going to start trainingcertifying physicians to be
certified as a meta, as a personwho can deliver metabolic
therapy.
So they've been trained and,and, and shown what to do and
how to do it.
And now they can go into the,into the communities and set up
clinics treating cancer patientswith metabolic therapy.
(45:20):
So a lot of the parts to do thisare not in place.
We don't have trained physiciansto do this.
A lot of the physicians don'twant to be trained, they want to
know about it.
But once you get certified, thenyou can open up clinics and you
can start treating patients the
0613 (45:34):
But how do we help someone now?
Someone with cancer now?
How do we help them now?
squadcaster-a27a_1_06-13- (45:39):
well, they, they then the, a lot of
the burden falls on them.
And, and I, I give kits out tothe folks that just has
educational information as I,I'm not a physician.
I cannot tell anybody what to door how to do it, but it can only
give them educational materialwith some names of people.
And then they,
0613 (45:57):
Let's do that.
squadcaster-a27a_1_06-13- (45:58):
Like, Yeah, and, and, and they, and
they're, and all I asked them todo is make donations to the
Boston College Cancer Fund on mywebsite or, or to Travis
Christofferson's foundationbecause all of our research is
supported by philanthropy andprivate foundations.
And the more funds that we get,we, the more people we can
train, the more experiments wecan do to convince the skeptics
(46:21):
that cancer is primarily amitochondrial metabolic disease.
So the evidence, the truth.
Just has to build and build andbuild and build so you work on
one side You work the scienceout on the other side you get as
you call them Anecdote afteranecdote fluke after fluke after
fluke after anecdote afteranecdote and it works on dogs,
too It's unbelievable the dogdogs are riddled with cancer And
(46:44):
we have a big paper on, onremoval of a mass, a mass cell
tumor on the face of a pit bull.
And that's published in an openaccess journal.
So, why should the dogs bemanaged and not people?
So, you know, it's, it's, it'sthe whole, the whole thing here.
It's a, it's a work, it's a,it's a momentum that's growing
and growing and growing andeventually will become the
(47:05):
standard of care.
There's no question about itbecause it's based on the
correct theory of what thenature of the disease is.
And when you have the righttheory, Just like the heavens,
we now, we have telescopesrevolving around the earth a
million miles, the webtelescope.
That would have not beenpossible if we considered the
earth as the center of the solarsystem.
It only became clear when theearth was another planet
revolving around the sun andthen the advance in astronomy
(47:27):
and these kinds of fieldsadvance.
Same thing will happen in thecancer field and in the chronic
disease field.
It's just a matter of time.
I have no doubt about it.
It's just that the word, it'sjust the
0613 (47:38):
Yeah.
The policymakers just have to,have to get old.
Right.
So then you come in.
squadcaster-a27a_1_06-13- (47:43):
well, you know, but you know, it's
tragic about that, what I feelabout that, and that's what Max
Planck said, you're, you can'tmove a new field theory forward
until the guys supporting theold theory die off.
But right now we're sacrificing1700 people a day for their, for
their resistance.
I mean, it's not, it's not, youknow, nobody needed to die if
you didn't, if you didn't, ifyou thought the sun of the earth
0613 (48:05):
If we could do it
squadcaster-a27a_1_06-13-202 (48:05):
it wasn't, it didn't.
So, so anyway, this is the,people want to live.
They're going to have torecognize that the cancer is a
mitochondrial metabolicdisorder, and a lot of the
treatment rests on theirshoulder.
But they have to have apractice, they have to have
certified practitioners that canhelp and guide them.
And right now we get you godown, and that's one of the
(48:28):
things that's so tragic.
I tell all these folks, thenthey go down to their, all
excited to go down to theirlocal oncologist and they get
slapped down.
They said there's no evidence tosupport any of this metabolic
stuff, diets don't work, youknow, fasting should never be
done.
I mean, what are they?
And that's only because theylack knowledge.
It's not because they're badpeople.
They just don't know.
(48:48):
Once they know, then they becometotally embarrassed and they
say, Oh, how the hell did we notknow this?
Well, I'm telling you now youshould know it.
And the papers are therepublished and you can read them.
0613 (48:57):
Absolutely.
You know, if if I don't doanother interview, I will be
happy with this interview.
I'm done.
I mean, there, I mean, cancer,again, is such a devastating
word.
You know, we talked about howthe deaths per year that we see,
It's it's such a scary, scaryfor people.
(49:19):
That's why I really want to getto help these people that are
struggling, know somebody that'sstruggling, you know, point them
in the right direction.
Where can people find you?
Maybe connect with you followyou and follow the research.
How, how can they connect withyou?
squadcaster-a27a_1_06-13- (49:33):
Well, I think we've done a lot of
YouTube videos for sure.
So people are starting to hearabout it.
And again, they, they, theyInstagram, you know, there's an
Instagram account.
One of my students, I've gotstudents now doing podcasts in
my, they're, they're actuallydoing some nice podcasts.
You know, it's a, it's a work inprogress.
We're training right now, as wespeak, there's a big conference
(49:54):
going on and in SwitzerlandJosephine Barbarino is, Is
starting to set up a place totrain trained clinicians.
It's a happening event.
It's going to be very exciting.
But I think right now you cansee all the work we've done on
open access.
Just go to look at all mypublications on open access,
become familiar with theevidence, and then start putting
(50:15):
pressure on the health careproviders to say, why are we not
doing metabolic therapy andsupporting the research that we
do and it will eventuallybenefit all of huma all mankind,
everybody, every there's nocountry that has no cancer.
Now there are some actuallyprimitive peoples living
according to their traditionalways, cancer is much less.
(50:36):
They're not, they're not it'sdiet and lifestyle once you
realize that, that are, we'renot getting enough exercise,
we're under stress, we're eatingpoorly, highly processed foods.
All of these impact negativelyon the mitochondria in some
organ and some tissue leading todysregulated cell growth or
obesity or type two diabetes orcardiovascular disease or
(50:57):
hypertension or high blood, allof these things, Alzheimer's
disease.
So again we put them all intothe chronic disease and you're
100 percent correct.
Cancer is a frightening diseaseonly because to treat it you
have to be poisoned, irradiated,and mutilated.
And people don't want that.
They want to know that there'sanother way that we can manage
this without having to sufferlike that.
And they, and if that doesn'tkill you, eventually the cancer
(51:20):
will kill you.
But 50 percent of the people aredying from the treatments rather
than from the disease.
It's a terrible tragedy.
So people have to know, Thatthings can get a lot better once
they understand that can't thenew, the new theory that cancer
is a mitochondrial metabolicdisorder.
0613 (51:37):
You know, even though this podcast, this podcast recording
is, there's a lot of passionhere because we, we believe that
we have to change, you know, thesystem, right.
But there's a, this episode isoffering a lot of hope.
For a lot of people.
And I, I feel like, you know, ifwe can just help that one
person, you know, spread thatword and we're doing the same,
(51:58):
we spread that word, you know,support Dr.
Thomas Seyfried's foundation.
And we'll link everything downin the description box below so
you guys can support Dr.
Seyfried's
squadcaster-a27a_1_06-13- (52:07):
Also, there's one, there's one more
thing.
I wrote only one book.
I never wrote any of thosesummaries.
People should need to know thatsome of those are pirated
things.
They say I wrote them.
I did not write them.
So you have to realize the bookthat you mentioned was the only
book.
It's a, it's, it's not cheap.
It's not 19 or any of thisstuff.
(52:28):
I feel really bad when peoplesay, Oh, I got your, I got your
summary and I didn't, it wasfull of misspellings and it
didn't wasn't clear.
I didn't write that.
I wrote only one book and peopleshould know that.
Because they're all buying theselittle review things that
aren't, that I, that are notwritten in the quality of
writing that I have.
So, it's kind of just, it's kindof just put together.
So yeah, so this is yeah, we'reworking on this and we're not
(52:51):
going to go away any time soon.
And we're going to push it untilthe, until the system changes.
0613 (52:56):
Yeah.
Obviously I'll do the same.
We'll link the book down in thedescription box below so you
guys can, can check it out by,by your book.
Cancer is a metabolic disease.
Is that right?
Let me see.
squadcaster-a27a_1_06-13-2 (53:08):
It's cancer as a, as a, as a
metabolic on the originmanagement
0613 (53:12):
is a metabolic disease.
Yeah.
Yeah, absolutely.
We'll link it down in thedescription box below.
So you guys get that book,
squadcaster-a27a_1_06-13-2 (53:17):
John Wiley, John Wiley Press.
0613 (53:20):
get that copy, get that copy.
Well, thank you so much, Dr.
Thomas C.
Freed for coming on and sharingyour story and sharing your
knowledge here with us today.
I believe that.
We are going to help that oneperson, right?
And if you have a chance tocheck out Dr.
Thomas Seafried's book, go aheadand check it out.
Get your, get your own copy,learn about the metabolic
(53:42):
disease you know, mechanism, youknow, educate yourself about it.
You know, there's nothing betterthan, you know, getting some
more information about this andso you can empower yourself with
that knowledge.
Dr.
Thomas Seafried.
Thank you so much.
squadcaster-a27a_1_06-13-20 (53:58):
Oh, thank you very much.
Nice to be here.
0613 (54:00):
Awesome.
Thank you.
Bye bye.
squadcaster-a27a_1_06-13- (54:02):
Okay.
Take it easy.
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