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August 7, 2024 176 mins

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On this week's episode we have Zack Roloff, PhD - ABD at the University of Minnesota. Zack shares his expertise and ongoing research in muscle physiology and metabolism. DISCLAIMER: we do deeeeep into the molecular biology at the beginning of the episode, so if you aren't interested in those specifics, you can skip forward when we break it down in layman's terms. At around the 53 minute-mark, we summarize the research. Then at around 1 hour and 33 minutes we begin Reid's Reddit Read's and broaden our discussion to apply Zack's research to more concepts in the world of health and wellness. 

Zack's is part of a lab that studies skeletal muscle physiology, specifically in terms of aging and sex hormones. Zack, however, is a bit of the black sheep (in a good way) within his lab. His research focuses on the relaxed states of skeletal muscle myosin and how those states are influenced by (or actually do the influencing of) metabolism. This is a very new and exciting area of research, and could change the way we think about metabolic diseases, obesity, type 2 diabetes, and all other areas of metabolism and thermogenesis. 

We talk about calorie intake, the influence of biological sex on metabolic function, hormone replacement therapy, cold water immersion, muscle physiology, menopause, aging. There is truly something for everyone in this episode!!!


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