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July 24, 2025 15 mins

Could a subtle genetic variation be impacting your kidney and autoimmune health in ways you never imagined? In this crucial episode of Wellness Focused, Dr. Bismah Irfan, MD, delves into the intricate world of the MTHFR gene and the vital process of methylation. Discover how MTHFR variations can affect detoxification, inflammation, and immune regulation, potentially contributing to kidney disease and autoimmune conditions. Dr. Irfan explains the science behind methylation, its critical roles in the body, and how targeted nutritional and lifestyle strategies can support this essential pathway for improved kidney and overall health.


Dr. Bismah Irfan, MD, is a board-certified nephrologist who takes a functional medicine approach to kidney care. In this episode, I delve into the often-overlooked but critical roles of the MTHFR gene and the methylation process in kidney and autoimmune health.

From explaining the science behind methylation and how MTHFR variations can impact it to providing actionable strategies for supporting healthy methylation through diet and lifestyle, I’ll walk you through this vital biochemical pathway and its implications for overall well-being. If you're seeking to understand the root causes of kidney and autoimmune issues and explore targeted support, this episode offers valuable insights.

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Dr. Bismah Irfan, MD

Facebook:https://www.facebook.com/KidneyHealthMD

Instagram:https://www.instagram.com/kidney.healthmd/

LinkedIn: https://www.linkedin.com/in/drbismah/

Website: https://www.drbismah.com/about/

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Produced by DrTalks: https://drtalks.com/podcast/

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