Episode Transcript
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Speaker 1 (00:05):
This podcast is
supported by Americans for
Medical Progress and was foundedand created through the Michael
D Hare Fellowship, awardedannually to support projects
that inform and educate thepublic about the critical role
of animal research in furtheringmedical progress.
The Fellowship honors the lateDr Michael Hare, a renowned
board-certified laboratoryanimal veterinarian who
dedicated his career toscientific and medical
(00:25):
advancements and who was deeplycommitted to animal welfare and
advocacy.
Hey, everyone, welcome into theFebruary edition of the Labrat
Chat NewsBite episodes.
I know it's been a while.
It's been what, danielle, sincedid we do it December 1?
I think it's been November.
Speaker 2 (00:44):
I don't think so.
Speaker 1 (00:45):
So December, january,
two months off.
Speaker 2 (00:47):
A little holiday
break.
I think in November we promisedwe were going to do better and
then we didn't.
Speaker 1 (00:52):
So sorry, just
promises get broken kids.
Speaker 2 (00:56):
But they shouldn't.
Speaker 1 (00:58):
My daughter's trying
to make me promise everything
and I refuse.
I don't promise them anythingever that I'm going to do,
because you never know.
Speaker 2 (01:07):
Yeah.
Speaker 1 (01:08):
And they have a
memory.
I don't want them to grow upand remember.
Speaker 2 (01:12):
The dad broke a
promise.
Speaker 1 (01:14):
Right.
So anyways, we'll just call ita little hiatus, a little
holiday break.
You know tough around theholidays and all that.
Here we are, february, february8th today, full swing Mardi
Gras season down here inLouisiana.
Speaker 2 (01:29):
Oh, very nice.
Speaker 1 (01:31):
So I have to get you
down here One of these years.
When is Mardi?
Speaker 2 (01:34):
Gras Like is it a day
or a week?
Speaker 1 (01:37):
So I don't know the
complete, like I don't know how
they figure out what day itchanges every year and so this
like next Tuesday is Mardi Grasday the 13th.
Speaker 2 (01:48):
Okay.
Speaker 1 (01:49):
Okay, but sometimes
it's like in March, and so I
don't know exactly how it's allfigured out.
But I guess maybe next timeI'll do some research on it for
you guys.
Claire knows, but she's nothere.
Speaker 2 (02:02):
We should have Claire
come on as a guest at some
point, then Right, we'llinterview you on the history of
Mardi Gras.
That's kind of fun.
We totally should Next timeTell Claire get ready.
Speaker 1 (02:12):
Okay, and there's a
ton of dog parades, so animal
related during Mardi Gras, sothose are cool, okay.
So last week, as a company like, we're usually open Saturdays
but half day, so we closed andthere's a morning Mardi Gras
parade out here in the city.
That was the first parade I'veever been in.
(02:33):
I've took the whole family outthrough stuff.
It was like a huge turnout.
You wouldn't think too manypeople.
There's thousands of peoplethere to watch people march with
dogs and you throw dog treatsand dogs going wild everywhere
running around eating treats.
It's a little chaotic, so butit was fun.
It was fun.
But yeah, mardi Gras, mardi Grasmy new favorite holiday Now
(02:57):
that we live out here, but itgoes on for weeks, like parades
start in January and they'llhave parades every weekend up
until, like the week leading upto Mardi Gras.
There's parades every day ofthe week, like all day, so it's
a little crazy.
It's a little crazy, it's alittle bit more like a day out
(03:19):
here where we live but more likein the city yeah.
Yeah, so, cool.
Speaker 2 (03:23):
Yeah.
Speaker 1 (03:24):
So but that's other
than that we haven't done really
anything too exciting, and I doapologize for background
barking and noise.
It's unavoidable today, thewhole family's home, I think.
In the four years which isunbelievable that we've been
doing this podcast, I don'tthink I've ever recorded just
like in the house with my wholefamily home.
Speaker 2 (03:44):
Yeah, so it'll be an
adventure.
Yeah, and this is the firsttime I don't know if my whole
family's home, I think one ofthem would go get that dog and
make him be quiet, because theyknow what we're doing.
You'd think, but they're justlaughing at you.
Speaker 1 (03:55):
Right, no, I'm sure
they're encouraging it.
Speaker 2 (03:58):
So, then, my update
is this is the first time in
four years of recording thatI've recorded from my house
alone, without people here,because my life updates and why
I've been unable to podcastrecord.
I am sort of switching fromlike well, I am switching.
I no longer work full time, Inow work part time from my house
(04:21):
.
Speaker 1 (04:21):
Congratulations.
Speaker 2 (04:23):
And then in May, when
my kids get out for summer
break, I will no longer beworking.
So this is sort of my like slowoutro to work and I'm kind of
helping, like transitioninformation and train new people
and all that jazz you know, ona part time basis.
Speaker 1 (04:42):
Is there a new person
yet?
Speaker 2 (04:45):
There's a new interim
director person but they posted
my job.
But obviously it's too soon andyou know the state takes
forever to hire people.
Speaker 1 (04:55):
Yeah, they'll be
hired by 2025 maybe.
Speaker 2 (04:58):
But you know, I'm
like trying to like leave good
notes and paper trail and allthat good jazz.
So like working from home islike life changing, like I'm
just wearing an oversized hoodietoday and it's magical.
Speaker 1 (05:10):
That is pretty nice,
huh.
Speaker 2 (05:11):
Like I don't have to
put on fancy shirts anymore,
like it's just, it's nice.
And the other really super funthing is because I have a little
extra time on my hands whilethe kids are at school, I am
getting back into horse ridingwhich is super fun.
Speaker 1 (05:23):
It's already started.
Speaker 2 (05:24):
I did.
Oh, I've met with a traineryesterday and I have a lesson
scheduled for next Monday, butthere's rain in the forecast and
this barn doesn't have anindoor ring, they just have an
outdoor one.
So I'm like fingers crossed,like don't you dare rain on my
parade, quite literally.
Speaker 1 (05:38):
I say go out riding
on the rain.
You know what would have costher to you.
Speaker 2 (05:41):
Well, you gotta watch
the footing and the mud and I
don't know, we'll see.
But I'm like super pumped and Ihaven't like ridden like
regularly in 16 years.
Like I grew up riding I was apretty good rider, but like I
pulled all my stuff down fromlike storage, Like my helmet was
like dry rotted.
Speaker 1 (06:02):
I'm like okay getting
a new helmet.
You still had all that stuff.
Speaker 2 (06:05):
I hoarded it because
it's like someday I'm getting
back into horse, it's like I'mdoing it.
And then I went to put, like mychaps on and I was like, oh, my
legs have changed in size, likethose don't fit anymore.
And then, like, when I met withthe trainer yesterday I kind of
joked.
I'm like I don't even know whatthe fashion is.
You know, I used to have fullchaps and nobody even sells full
(06:25):
chaps.
She goes oh yeah, that's solike that was 2000s, like now
it's like you know the silicone,grippy riding pants with half
chaps.
And I was like, oh, my God, myfashion is so 2000s.
Like what just?
Speaker 1 (06:36):
happened.
Right, you need to up yourhorse fashion.
Speaker 2 (06:39):
Yeah, but at the same
time I freaking loved riding in
full chaps and I'm not going tolike go do showings.
Like maybe I don't care andmaybe I just find a way to get
new chaps, I don't know.
Speaker 1 (06:48):
She's not going to
follow the trends.
You're going to do what youwant to do.
Speaker 2 (06:50):
I've never been one.
Yeah, I've never been one fortrends, but what I will say is,
if I have horse riding listenersout there, please send me links
to your favorite riding pants,your favorite riding gloves,
because I got to get a new pairof gloves.
I don't know what's cool andwhat's in, and so like, spam the
like lab rat, chat, socialmedias with your suggestions,
(07:11):
because I also pulled my oldpaddock boots out.
Have like a pair of Ariottpaddock boots from the early
2000s, probably like the 1900s,dare I say.
Yeah, so outdated, yeah, butlike they still fit and they're
fine.
I shined them up, but they'repaddock boots.
So, like I don't know, isAriott still like the cool brand
?
Like I need to know thesethings.
The horse people spam me withyour best items so I can start
(07:35):
picking and choosing, becauseI'm about to get like back into
it.
Speaker 1 (07:39):
So he sound pretty
pumped.
Speaker 2 (07:41):
I'm so pumped, I'm so
pumped.
Oh my gosh.
Speaker 1 (07:44):
You didn't get your
kids into it.
Speaker 2 (07:46):
Yeah, oh, griffin.
Griffin already is like like,yeah, I want to ride a horse and
I'm like, well, like I don'tmaybe this.
This barn is like a smallerbarn and they don't really have
show horses.
The trainer has horses that arein training and the owners
allow her to use them forlessons.
So they're not really horsesthat you'd want to go like put
your kid on.
Yet but like I think as thesparring grows it might turn
(08:07):
into more of that.
But it's like new construction,it's a beautiful place, it's
just kind of like up and coming,so to speak.
So Nice.
Very excited and Morgan alsowants to ride horses, but she
tells me very specifically thatit has to be a tiny pony.
She doesn't want to ride ahorse, it's a tiny pony.
She wants me to get her a tinyhelmet because her head is
(08:29):
smaller than mine.
She's very specific things.
She's like no, I want a tinyhelmet and a tiny horse, a pony,
a unicorn?
Yeah, probably, well, shedoesn't really know, I haven't.
I haven't really done the wholeunicorn thing because I'm just
so into horses that it's like,no, you're just going to have
horse imagery and not unicornsand Pegasuses, pegasi, pegasuses
.
Speaker 1 (08:49):
Yeah, I don't know.
I don't know how that.
I don't know I don't know theplural of that one.
Speaker 2 (08:52):
Yeah, yeah, it's more
, more, just horse, straight
horse stuff around.
Speaker 1 (08:56):
Yeah, I think.
I think at least one of my kidsbelieves unicorns are real, so
it's okay.
Speaker 2 (09:03):
I mean, do we know
for sure that they're not?
Speaker 1 (09:06):
Correct.
Speaker 2 (09:07):
I thought Norwhals
were fake for a while, until I
realized that they are real andthat's a unicorn of the sea.
Speaker 1 (09:13):
So yeah, those are
kind of nuts.
They actually didn't believe me.
They didn't believe me thatthose were real creatures.
Speaker 2 (09:19):
Yeah, like those
actually are real.
So who's to say that there'snot an actual unicorn out there?
Speaker 1 (09:24):
I don't think they're
extinct though.
Is that right?
I mean, I don't know, I don'tknow.
Speaker 2 (09:27):
I feel like
everything is.
Speaker 1 (09:29):
Just want to be nice
to have like a producer that's
like sitting in listening to usand they could look these things
up for us and like beam intoour ears factual information and
let us know.
But we don't have that so no.
We'll just look it up later.
We're still looking at us nowthat they're indeed like there's
.
Maybe they're like overwhelmingpopulations somewhere.
Let me step up out of I don'teven know where they live.
(09:50):
Like are they live like in theArctic.
Speaker 2 (09:54):
I think they're cold
weather.
I think they look for the likeI see stuff.
I mean I'm pretty sure they'rein the baby beluga book that
that is all like Arctic, and I'mbasing that you know that's has
to be a fact because it's achildren's book.
Speaker 1 (10:09):
So right, there would
be nothing wrong.
Speaker 2 (10:11):
Yeah.
Speaker 1 (10:13):
Okay.
Speaker 2 (10:14):
All right Science
Should we talk about?
Speaker 1 (10:17):
science.
We should All right.
So my two articles I'm going totalk about are the first one's
going to be about ants.
And actually, you know it's oneof them.
It's not going to be the firstone, but it's going to be about
ants and how they can.
They can treat each other'swounds and how we might be able
to use that information forourselves one day.
(10:39):
And then the other one is aboutmice and hopefully providing
some insight into better allergytreatments for humans.
Speaker 2 (10:48):
Okay, I have like I
think this is going to be like
the best article of our episode.
Speaker 1 (10:58):
You have to stay in
Excel, huh Okay.
Speaker 2 (11:00):
Yeah, no, this is big
.
I'm actually surprised youdidn't find this article Pig
liver transplants to humanspotentially potentially Because
we've talked about hearts andmaybe kidneys, but now we're
looking at livers.
And then I also found a studyon with mice involving.
Well, like it's about breastmilk and everyone knows that
(11:20):
breast milk is beneficial, blah,blah blah.
But it's like a new mechanismin breast milk that they hadn't
really figured out yet.
So it's just kind of anothercool piece of that.
You know mythical science ifyou believe in that.
So Super.
Speaker 1 (11:37):
All right, you want
me to go first?
Speaker 2 (11:39):
Sure, I kind of want
to know about the ants.
I know you said it might not bethe first one, but I kind of
want to know.
Speaker 1 (11:45):
I mean, I can always
start with the ants.
Speaker 2 (11:47):
Okay, do it.
Speaker 1 (11:49):
Actually All right,
starting off with the ant story.
So these ants I don't know howto say this type of ant
Matabelle M-A-T-A-B-E-L-E.
Speaker 2 (12:02):
Matabelle Okay, ants
Okay.
Speaker 1 (12:04):
And there's a dog
voraciously, viciously, trying
to break in to this playroom toget to me where I'm at.
Speaker 2 (12:11):
Nice, I'm crying now,
yeah.
Speaker 1 (12:13):
Yeah, the dog's not
crying, that's probably a kid.
They're in the sub-SaharanAfrica and so these Matabelle
ants, metabelle ants I don'tknow how you say it, I'm going
to keep saying it wrong they canactually.
They find out, they canidentify and then treat infected
(12:35):
wounds with antibiotics thatthey actually produce themselves
after they get into thesebattles.
So, like I said, they live inthe sub-Saharan Africa, they
live in these huge colonies andthey only eat termites.
And so there's tons of termitesout there, you've seen, like
those giant termite mounds andstuff.
(12:55):
So that's the only thing theyeat.
So they have to move their bigcolonies to go find these
termite mounds and then they goand attack.
So as they start approachingthe termite troops also, like
you know, they try to defendtheir mouth.
So then it's like this huge warof these ants versus termites
(13:15):
out there fighting each other.
Oh God, the ants typically win,it sounds like, but afterwards
many of the ants this is what itsays many of the ants lose legs
or wings or other parts oftheir body in the battle, and
they will, I guess, after theyeat the termites and stuff, then
(13:37):
they will take their fallen antbuddies back to their nest.
So they're to their colony andthey actually will start licking
the wounds for several minutesand they didn't know why they
did it.
I mean, obviously you assumethat they're trying to heal it.
They just always said that theythought they're like removing
(13:57):
dirt to try to clean it.
But I guess they have theselittle glands on their backs,
these meta-pleural glandsthey're called and that secretes
a substance which contains morethan 50 different antimicrobial
and wound healing properties.
So they actually went in andthey took some of these ants and
(14:18):
they extracted these glands andlooked at the chemical makeup
and saw that's made up of allthese things.
So as they're licking theirwounds, they're taking the
secretions from this gland andoff of their bodies and applying
it to the ants and it helpsthem heal.
And they found that theyactually took.
The researchers took some ofthe injured ants away from the
(14:41):
colony so that they couldn't betreated by their fellow ant
mates, and 90% of those antsdied within 36 hours, whereas
the ones that they just leftwith the colony only 22% of
those ones died.
So clearly the ants that's likemind boggling.
Yeah, they have life-savingantibiotics, so as they lick the
wounds, they actually arehealing them.
(15:02):
So I guess we're going to tryto figure out more about this
chemical makeup of the gland andmaybe we could possibly use it
in treating all theseantibiotic-resistant wounds that
we have, because wound healingis a big issue and all that
other stuff out there.
So just one more area to lookinto and one more tool maybe to
(15:22):
help battle some of theantibiotic resistance that's
going on out there and we use AIto make a photo of a field of
ants with swords and shieldsrolling up on a termite mound
and the termites have tanks andhelmets on and they're like get
back inside.
Speaker 2 (15:43):
Can we make that
photo happen?
Speaker 1 (15:46):
I mean, I don't know
how to do that, but if somebody
out there knows how, that wouldbe great.
Speaker 2 (15:51):
Yeah, because that's
all I was picturing.
Speaker 1 (15:52):
I know you can make
awesome AI art now.
But I know with chat, gpt orwhatever number it's on now, I
think you have to pay to getartwork.
The free stuff just gives youthe text.
Speaker 2 (16:05):
Did you see the post
I put on our Instagram and
Facebook with the?
Ai conversion of my chickens?
Speaker 1 (16:11):
Yes, Because I
laughed out loud to myself yeah,
how does you?
Is that an app that you use todo that?
Speaker 2 (16:19):
It's an app yeah, I
don't remember what it's called
Wonder maybe but you take apicture of your dog and you
upload it and it turns your doginto a cute little Pixar-looking
dog.
I think it can only handle oneanimal or two people and clearly
can't handle a group offeathery things.
Because I was just out droppingsome sunflower seeds for my
birds, I took a cute picture andI was like ooh, let's see what
(16:41):
AI does with this one and whatit gave me.
Speaker 1 (16:45):
That's hilarious If
you're listening and you haven't
seen it yet the bears arepretty hilarious, the bears.
Speaker 2 (16:50):
There's a girl out
there riding the back of a
chicken.
Go look at our social media tosee the series of photos of the
original chicken photo.
And then there was one wherethey turned into red-nosed pigs
and one of them had a necklaceon.
I don't understand that.
Speaker 1 (17:06):
And then I mean,
they're cool photos, they're
hilarious, which is how they getthem.
Speaker 2 (17:10):
And then there's one
with the bears who are shocked
to see a small girl in the.
It makes no sense.
So I love AI.
I hate AI because it confusesme, but I also love it.
Speaker 1 (17:23):
It's really nice for
work, sometimes Like if I do a
surgery I'll go into the AI andjust say write a surgical report
for the surgery, and it istextbook.
Speaker 2 (17:34):
Really.
Speaker 1 (17:35):
Yeah.
Speaker 2 (17:35):
Nice.
Speaker 1 (17:36):
I mean, I think it
just scours the literature and
textbooks out there and itwrites exactly.
I mean, obviously you have togo in and edit things.
Yeah, that's how I got a lot ofmy templates originally,
because I just had to do thatand then I went and changed and
edited things to how they shouldbe.
But it's a little crazy.
Nice.
What the thing is that they cansave so much time but still
(17:57):
needs some oversight.
You got to review it, butanyways, yeah, all right.
Speaker 2 (18:03):
Well, I want to.
Yeah, so that's about ants.
Yeah, that was much cooler thanI thought it was going to be.
Speaker 1 (18:09):
Good.
Speaker 2 (18:10):
So I'm going to just
start big with my awesome
article and people will probablyget bored after this because
now we will have given our twobest articles.
But first ever pig liver, not atransplant.
So this started out there was,unfortunately, a patient that
was brain dead.
They knew that they were goingto be taking the patient off
life support and University ofPennsylvania was able to do this
(18:32):
experiment before that happenedand they kind of they used the
box that they hold livers inbefore a transplant.
So it's like a environmentalchamber that keeps the liver
happy between patients.
If you had a human liver to ahuman liver.
So they had this geneticallymodified pig liver in there and
they have a cool picture of itwith all the tubes and things
(18:54):
hooked up to it.
And they hooked it up to thepatient and were able to keep
the pig liver alive.
The pig liver successfullyfiltered blood and everything
else that livers do back to thepatient for 72 hours.
The article doesn't say ifmaybe 72 hours was just the max
that the hospital allowed.
(19:14):
It doesn't say if it started tofail after 72 hours.
I'm thinking it might have justbeen a 72 hour endpoint to the
experiment and the pig liver Ithink it came from a pig with 69
modifications.
I read a different article lastnight than the one I found this
morning and I think the one Ifound last night mentioned it
was 69 genetic modifications.
But the implications of thiswould be, you know, there's like
(19:37):
10,000 people on the livertransplant list and you've got
people in acute liver failure.
And if you can have even atemporary pig liver that can
filter and do the job of a liverfor 72 hours or longer, or
maybe you, you know, get a newliver every week or something
from a different pig but if youcan keep those people alive
longer to get them on atransplant plant list or allow
(20:01):
their liver to heal in I don'tknow how long it takes livers to
heal, but, like, maybe there'sa way to kind of give your own
liver arrest, use one of theselivers and, you know, help
people stay alive longer.
So this is super exciting.
Another kind of article about,you know, the future of
genetically modified pig organtransplants.
Speaker 1 (20:21):
It seems like the
world of pig organ transplant
plants is just growing rapidly.
Speaker 2 (20:27):
It's crazy.
Yeah, it seems the mostfeasible because it's not like a
permanent.
Like gosh, you know, if youhave a heart transplant, like
you got one shot with that thing, like you know what I mean.
It's in your body, you had thissurgery, but this is like it's
external to your body, it's justkind of operating as a liver,
because they've never made amachine Like, yeah, for kidneys
they have a dialysis machine,but they don't have like a liver
(20:48):
dialysis machine.
So this could be a huge benefit.
And again, it's outside yourbody.
So if, like, the pig liverfails, you know you can maybe
get another one, or like it justseems like you have a more
wiggle room for things thatcould go wrong.
Speaker 1 (21:06):
Right, or maybe you
could switch back to your own
liver for a little bit, for alittle bit Like yeah, it's not
like you know, if you have a pigheart in your chest and it
gives way, then you're done.
So yeah, and depending onwhat's going on, like you said,
could possibly regenerate itselfand heal itself a little bit in
the meantime.
And yeah.
And who knows, maybe eventuallygo back to just your own liver
after a certain amount of time.
Speaker 2 (21:27):
So super cool.
I was pretty pumped when Ifound this one, pretty pumped
like a liver pump, sorry.
Speaker 1 (21:36):
That's lame.
Speaker 2 (21:37):
I know I was joking,
that was good.
Edit that out.
No, just kidding.
Speaker 1 (21:43):
We don't edit
anything out.
Speaker 2 (21:45):
I know you get what
we say yeah.
Speaker 1 (21:50):
So I guess now it's
into two.
Exciting articles are out theway.
If you want to go ahead andjust turn the episode off, feel
free.
We got two more though, allright, okay.
So my next one's about a mousestudy that hints at a new way to
counter allergies.
So I always liked the way that,like journalists and these
(22:13):
writers start articles so Icould always kind of like read
the beginning, like they're socreative, but they're not really
.
But it just starts withallergic to peanuts, to cats, to
pollen, and that's how itstarts.
Nice, okay, like just extrawords that we don't need.
Like that's not drawn me intothe article.
Speaker 2 (22:32):
Let me list some
allergens that are common.
Speaker 1 (22:34):
Yeah, have you had
your kids allergy tested for
anything?
Just sidetracked?
Speaker 2 (22:39):
I have not but I do
think that Morgan might have,
like she has like a tentativeasthma diagnosis now because she
has had a cough since Augustand we finally found some like
inhaler meds that are working,but I almost feel like it's like
a allergen that's.
I don't know, we haven't yet,but it might be in our future.
Speaker 1 (22:58):
Yeah, yeah, I've had
that for a long time and see,
she put on some steroids and itfinally went away.
Speaker 2 (23:07):
Yeah.
Morgan's had five days ofsteroids which helped it for
five days, but then it came backafter the steroids.
Yeah.
Speaker 1 (23:13):
Yeah, anyways, only
because it's talking about
allergic to peanuts, to cats, topollen.
Well, I have allergy tests withany of our kids.
They all seem fine.
But have you heard of people?
Why are cockroaches on theallergy panel for humans?
I feel like it, think about itthough.
Right.
People are allergic.
I feel like Terminex has tosponsor that in the profile.
(23:36):
Yeah, make sure cockroaches areon there.
Speaker 2 (23:40):
No, but if you live
in Louisiana, don't you open
your door and have I don't know?
I remember one time we wentdown to my father-in-law's.
He had a condo down in Floridaand we opened the door and they
weren't cockroaches, but theywere the what's the Florida one,
palmetto bugs.
Am I making that up?
There was four of them.
Speaker 1 (23:57):
Yeah, they look like
cockroaches.
Speaker 2 (23:59):
Yeah, they do, and
they just ran into the apartment
from the door frame becausethey were just chilling in the
door frame.
I ran in with my flip-flop andI just took my flip-flop off and
I started whacking them and myhusband he was my boyfriend at
the time.
He was looking at me.
He was like what just happened?
I'm like you got to get thesethings.
And he's like no, I know.
He's like I'm impressed.
I was like okay.
Speaker 1 (24:18):
But I mean if they're
in your house yeah, I mean,
they get in.
Yeah, but how allergic are youto them and the fact that
they're just like even in yourhouse?
You're going to have some sortof allergic reaction.
Speaker 2 (24:30):
Well, is it to them
or is it to their like urine and
poop, like I feel, like that'swhat would cause the allergic
yeah.
Speaker 1 (24:38):
So but that's an
exterminator company had
definitely sponsored that to beon there.
And then when he comes back andthen they're like okay, well,
now you got to get anexterminator out there and make
sure there's no pesticides ormake sure there's no cockroaches
.
It's just re-diculose allergy.
Sorry, if you have it.
Speaker 2 (24:53):
Yeah right, it's not
first, it's insulted.
It's not personal, it'sinsulted all of our listeners.
Speaker 1 (24:59):
But anyways, all
right, so anyways.
So there's no.
So when you have allergies youhave these mast cells.
That when, in response to anallergen, the mast cells dump
all of those histamines into thebody and then that those
histamines incite that a massiveinflammatory response where you
get itchy eyes or sneezing oreven anaphylactic shock possibly
(25:21):
, and so there's, you know, like, in response to anaphylactic,
you get like your EpiPens and inresponse to the itchy eyes and
runny noses, you got pitidary onall that stuff.
So everything that we have iskind of like a way to treat the
symptoms.
But these people out of I'llfind it in a minute, doesn't
(25:43):
actually say out of NorthwesternUniversity, they're using
nanoparticles to actually go inand deactivate the mast cells
and so mast cells are importantfor other processes in the body,
like blood flow and fightingoff parasites and things like
that.
So we can't just shut them alldown.
(26:03):
But I guess these nanoparticleshave a way to disable specific,
just allergy related mast cellsthrough a different like,
through a whole different liketwo step process.
So they coat the nanoparticleswith an antibody and then they
(26:23):
carry like an allergens specificto that person's allergy, so
like peanuts or something.
So to treat peanut allergy.
It would contain a peanutprotein and then the antibodies
on the nanoparticle engage withthe receptors, like on the mast
cells, and they inhibit thatspecific mast cells response to
the allergy and then those.
So rather than shutting downall the mast cells in the body,
(26:47):
it becomes very specific.
The nice thing about thisapproach is you don't have to
actually kill or eliminate thosemast cells, and if the
nanoparticle were to like attachto the wrong cell type, it just
wouldn't like.
Nothing would happen, and so ithas a good like.
There's a wide safety profileto it as well.
I'm sure there's some otherconcerns and other safety issues
(27:08):
and all that too, but theyshowed when they did this in
mice.
The therapy was so they hadmice and obviously they can
develop mice models for anything.
So they had mice that developedan allergy and then they
treated them with thesenanoparticles and it was 100%
successful in preventing allallergic responses.
(27:29):
So, none of them developed anyof their allergies to the
allergy when they exposed it toit.
Speaker 2 (27:34):
Can that work for,
like, let's not even translate
that.
I mean, let's translate it tohumans, but can we also
translate it to, like, our dogs?
Because Nala has allergies?
My goodness, she has allergies.
Speaker 1 (27:44):
Yeah, I don't know
that would be awesome.
Yeah, that would be sweet, huh,I mean all we do, I mean half
of, especially down here inLouisiana, like half of my half
of my client to bring it inthere their pets for allergy
related issues out here, andthey're just year round, you
know.
Speaker 2 (28:03):
Yeah.
Speaker 1 (28:04):
So, then, treating
the symptoms would be nice to
just be able to give themsomething that can prevent it
all together.
Speaker 2 (28:10):
Yeah, that's awesome.
Nala's allergic to dust mites,storage mites and chicken, so
that's.
Speaker 1 (28:17):
Chicken huh yeah.
Speaker 2 (28:18):
Chickens are common?
Speaker 1 (28:19):
Yeah, chicken and
beef are common, but did you say
storage mites?
Speaker 2 (28:24):
Yeah, Dust mites,
storage mites, dust mites and
storage mites what's the?
Speaker 1 (28:27):
difference between a
dust mite and a storage mite.
Speaker 2 (28:29):
I don't know if
there's a big difference,
because they were on the sameline.
They just had a slash betweenthem, so maybe they're just like
called one of these different.
I don't know.
But I mean, you can't escapedust mites and storage mites.
What the vet explained to us,this was gosh 10 years ago.
Storage mites are in dry kibble, because dry kibble is stored,
even if it's vacuum packed, evenif it's yeah, you can't avoid
(28:51):
it.
You can't avoid it, which is whywe originally switched her to
raw food.
Both of our dogs are on rawfood just because it's easier
now.
But as soon as we switched, herskin cleared up, and it's just
because the dust mites in thedry kibble were no longer a
problem.
Speaker 1 (29:06):
So storage mites,
yeah, I don't know.
Speaker 2 (29:08):
Storage mites, dust
mites.
That's what the printout saidof her allergy testing.
Speaker 1 (29:14):
Awesome.
Speaker 2 (29:15):
Yeah.
Speaker 1 (29:16):
Yeah, I know I
actually use your dogs a lot at
work.
It's like an example for somepeople that just need you know
cause we talk about food trialsand eliminating like a lot of
times it's food allergies andstuff or it could be like you
said dust mites and things likethat.
You know we're always tellingvet school so much how awful raw
(29:36):
diets are, but I'm like, listen, I've been friends been doing
it for like 10 years and we'venever had a problem.
Speaker 2 (29:41):
I remember when you
started vet school I like
threatened your life and I'mlike don't you become a
brainwashed vet into thinkingthat this is a bad thing.
It's just that people do it badand then it's bad.
But if you do it right.
Speaker 1 (29:53):
It's amazing, yeah,
yeah, and vet schools are so
adamantly opposed to it.
I did have our nutritionist.
She was pretty good.
She was pretty open about it,but you know the giant the
nutritionist average in yourtech.
Yeah.
Speaker 2 (30:08):
Well, that's who my
vet.
My vet was like oh, there's areally good nutritionist out at
VT that can help you balanceyour diet, and I'm like it's
already balanced, cause we'vebeen doing this for a while?
Speaker 1 (30:18):
Yeah, cause I talked
to her about it but after one of
our classes and she was I meanobviously like took it as like a
last resort kind of thing.
But she's like you gotta do it,you gotta do it and just do it
right.
Speaker 2 (30:30):
Yeah, no, don't get
me wrong.
There's nothing more convenientthan like kibble, especially
when you have kids, because,like for us, like we need to
make sure that the kids don't gotouching the raw meat that's in
the garage where we feed thedogs, like it's a whole process
to make sure we're handling thefood safely, and blah, blah,
blah.
Speaker 1 (30:46):
But like and you're
not just giving them like raw
ground meat, like you give themeverything.
Speaker 2 (30:51):
Oh yeah, it's a whole
whole fiesta.
We could probably have a wholeepisode on this.
Yeah.
Speaker 1 (31:00):
And so I'm always
supportive of it.
If anybody ever wants to do it,Just try to give them the
information to make sure they doit right.
Speaker 2 (31:07):
Yeah, I mean like you
said, though for us it was kind
of a last effort because we didtry all the different kibbles.
We tried steroids and I knowthat they say dogs don't get
roid rage, but my goodness, nalahad roid rage on this.
Speaker 1 (31:18):
Yes, they do.
Speaker 2 (31:20):
And we were like
that's like, she's a puppy,
we're not dealing with roid ragefor the rest of her life.
So as soon as we switched it,it worked its way out, so that
was good.
Speaker 1 (31:28):
Yeah, I mean they get
.
They have a whole host of sideeffects, you know, you get liver
issues, they get fat pudgy theydrink a lot, they pee all the
time.
They pee all over your house,you know so, but yeah, we could
spend a whole day talking aboutit.
All right, the dog hasofficially broken into the
playroom.
Speaker 2 (31:48):
Okay, Now that the
door is open.
Speaker 1 (31:50):
the kids are gonna
start flooding in, All right,
well, I'll finish up.
Speaker 2 (31:52):
I'll finish up my
last article quick.
Okay, so out of Johns Hopkinsthey did a study on new
protective benefits of breastmilk.
Obviously this is mouse breastmilk.
But what they did and I theydon't ever go into the mech, the
mechanisms of how they did itbut they had mice that they
could like turn off the genethat makes these complement
(32:15):
proteins.
So they compared that groupwith mice that were just normal
doing their thing, and the mice,the mouse pups that had the mom
who had the complement proteinsturned off.
They were more susceptible tobacterial infections in their
gut in early life, whereas theI'm gonna use quotes the normal
(32:35):
breastfeeding mom, her pups werekind of immune to this and they
found that it's actually notrelated to so complement
proteins.
I'm jumping all over the placewith this because I'm trying to
rush because you said your kidsare gonna come in, sorry.
Speaker 1 (32:48):
Take your sweet time
yeah.
Speaker 2 (32:51):
So everyone, all the
science, knew that complement
proteins existed in breast milk,but they thought they worked in
conjunction with antibodies.
But this study kind of showedthat they work independent of
antibodies and do their ownthing and they also, like your
blood, has complement proteinsas well for just fighting other
(33:12):
infections in your body.
But this is a specificcomplement protein in breast
milk that works on its own,doesn't need any of the other
help out there to kind of offerprotection for the mouse pups or
, hopefully, human pup I almostsaid human pup, human baby,
(33:34):
human pups yeah, human pups, thegut microbiome and the gut
flora.
So it's just an interesting newunderstanding of how breast
milk works because, like I said,it's sort of a mythical thing
that everyone knows is airquotes good for you, but there's
just so many different ways itworks and how it works and I'm
(33:55):
just always interested inreading about that sort of thing
.
Speaker 1 (33:58):
So yeah, it's always
nice.
It's always nice to know I knowwe had a freezer for a while
there.
I mean I was not a little kid.
Speaker 2 (34:07):
Yeah.
Speaker 1 (34:08):
Like well, I guess
we're prepared for Armageddon.
Just in case you know, I know.
Speaker 2 (34:14):
And this is gross,
sorry everyone, but like, yeah
to say like we had a freezerfull too and I like mason jars
of it and I was like why am Ihoarding all of this, like I
don't know?
Speaker 1 (34:23):
Hey, you never know.
Speaker 2 (34:25):
I think we can get
rid of it now.
Speaker 1 (34:28):
Yeah, I mean it's.
It does so many.
There's so many like healingproperties in it, Like I'm out
of it, Like Claire's mom wouldalways tell her like use it on,
like rashes and diaper rash andall that stuff too, and it would
work magically.
Yep, you have to like healeverything.
Speaker 2 (34:43):
So, yeah, I was
intrigued to see this headline,
just cause it's a an interest ofmine and I was curious what
they had found out.
Speaker 1 (34:50):
So yeah Well, if PETA
got their way, we would stop
using cow milk for ice cream andwe would start using human
breast milk to make ice cream.
Speaker 2 (35:02):
You should have seen
the eye roll when you said PETA,
we would stop torturing thosecows for their milk.
Well, so I was like I was theother day.
I was walking in from cleaningout my chicken coop and I was
thinking about like oh, ourgarden for the spring and like
what do we want to plant andeverything.
And I kind of was like, okay,so like millions of years ago,
like who was the first personthat tried cow milk?
(35:25):
And that was where I went inwhile I was wandering through my
backyard, like who realized,hey, maybe I can have milk from
another animal, let me go getthat wild cow out there and see
if it'll.
Let me.
Like how did that start?
Cause obviously they didn'tjust have domesticated dairy
cows millions of years ago, notmillions, what are we talking?
Tens of thousands of years ago.
(35:45):
When did people?
Speaker 1 (35:46):
start drinking milk,
maybe billions, you know?
Speaker 2 (35:49):
Yeah.
Speaker 1 (35:50):
All the I mean, there
could have been advanced human
civilization long before we,long before us, for all we know.
Speaker 2 (35:56):
Did people like
domesticate cows for meat and
then they're like, hey, maybe wecan also and like find a nice
cow and like try, like, how didthat evolve?
How did humans start drinkingcow milk?
Speaker 1 (36:08):
I don't know.
Speaker 2 (36:10):
And you know.
Speaker 1 (36:11):
you'll know who I'm
talking about Butter and cheese
and everything, and maybe it'sjust like well yeah let's drink
some of this.
You'll know who.
Speaker 2 (36:19):
I'm talking about,
but you know that we used to
have the co-worker who saidcamel milk was the best.
Speaker 1 (36:23):
So yeah, there is
some research out there that
camel milk is pretty great.
So we're actually and I guessdonkey milk is the most similar
to humans.
Why anybody would ever want todrink donkey milk, I don't know.
Speaker 2 (36:39):
But why is that any
different from drinking cow milk
?
Speaker 1 (36:43):
I mean you're right,
but I love milk.
Don't get me wrong, I don'tdrink, I would probably try.
I've never tried camel milk,but why not?
You know, I mean if we're, butwhy?
Not, you know.
I mean, if we're.
Speaker 2 (36:58):
If we're drinking cow
milk, you might as well throw
in a donkey and a camel too.
Speaker 1 (37:03):
Yeah, but people that
are so adamant about we
shouldn't be drinking cow's milk.
It just drives me.
I love nuts.
They're like we're the onlyspecies that drinks milk from
another animal, but we're alsothe only species.
That drives cars and yes, I'vetalked about this before, so.
Speaker 2 (37:21):
Develops science,
research, and then yep, they
still want to eat ice cream andbutter and cheese.
Speaker 1 (37:24):
I'm like, well, it's
all coming from, there's dairy
and all of it.
Speaker 2 (37:29):
No, they make almond
milk and coconut milk ice cream
now.
Speaker 1 (37:34):
Yeah Well, your
almond milk is killing the
environment, okay.
Speaker 2 (37:36):
Yep, no, I know about
that.
I think I talked about that onetime right With the bees.
The almond industry is takingout the bees.
Speaker 1 (37:43):
Yeah, there's no.
There's like there's nothingaround almonds.
There's no bees, birds, insects, animals, nothing.
Speaker 2 (37:52):
Yeah, well, okay.
Speaker 1 (37:55):
So let's just get
super weird.
No wait, I'm going to add onemore thing.
It's super weird and personal.
Everybody stopped listening bythis point.
We can say whatever we want.
Speaker 2 (38:01):
This is all relevant
because we're talking about
allergies, we're talking aboutbreastfeeding and we're talking
about almonds here.
So both of my kids I breastfedthem.
Now we're getting weird butthey were allergic to me
drinking dairy and having dairyso I had to totally cut dairy
out of my diet, have almond milk.
That's how I found thedairy-free cheese that actually
(38:23):
melted correctly on a pizza andstuff.
So it really does come fullcircle.
And then they outgrew it andnow they can have dairy.
So I mean, maybe there is somegenetic thing that says humans
shouldn't have other animalsdairy, but I don't know.
They outgrew it, so it's fine.
But, that does kind of come fullcircle with everything we just
talked about on this episode.
Speaker 1 (38:42):
Yeah, yeah, I mean
I've never had we all were big
milk drinkers gallons andgallons a week in this house.
We're just.
I mean we need to get a cow inthe backyard.
Speaker 2 (38:54):
Or a donkey or a
camel.
Yeah, why don't you?
Speaker 1 (38:57):
Get them all, yeah,
but wait until I tie it all
together there at the end.
Speaker 2 (39:02):
Yeah, and make people
feel a little awkward talking
about what I.
Speaker 1 (39:06):
That's how you end an
episode, right there, so all
right.
Well, hopefully we will.
I'm not making any promises,but hopefully we'll do our best
to be back next month withanother news bite and hopefully
sounds like maybe some otherthings on the works, and get
some interviews Start rollingagain.
Speaker 2 (39:24):
Yeah, Get the
momentum going, especially now
that I have a little bit moretime because I'm kind of doing
the part time thing.
So hopefully it'll be good.
Speaker 1 (39:31):
Yeah, so put it all
on you.
If we do an interview episodenext month, it's all because of
you.
Speaker 2 (39:36):
I wouldn't say next
month.
It's also because of you.
That's probably too fast, butwe're going to try.
Speaker 1 (39:40):
Yeah, all right.
Well, thanks for listeningeverybody, and we'll check you
out, or we'll.
What was I going to say?
Speaker 2 (39:46):
Check you out.
Check you out.
Speaker 1 (39:47):
I was going to say
check you out, but that's not.
Yeah, we'll check in witheverybody next month on another
episode of the Live Brat Chat.
Thanks for listening.