Listen In - Bitesize Bio Webinar Audios

For many researchers, modern science has become about getting results rather than asking questions. Results mean publications, and publications mean more funding.

However, results are not the objective of the scientific method, which involves proposing an answer to a question, designing experiments to determine whether the proposed answer is true or false, and objectively interpreting the results.

This episode of Listen In ...

For many researchers, modern science has become about getting results rather than asking questions. Results mean publications, and publications mean more funding.

However, results are not the objective of the scientific method, which involves proposing an answer to a question, designing experiments to determine whether the proposed answer is true or false, and objectively interpreting the results.

Nonetheless, the results-f...

Volume electron microscopy or volume EM (vEM) was named one of Nature's Technologies to Watch in 2023. The new Thermo Scientific Hydra Bio PFIB integrates advanced cryo-TEM lamella preparation to volume EM workflows.

In this episode of Listen In, see how the new Thermo Scientific Hydra Bio Plasma-Focused Ion Beam (PFIB) extends cryo technology to volume EM and enables the acquisition of high-resolution 3D data through autom...

In this episode of Listen In, see how emerging and global challenges of conducting ethical animal research have led to the 12Rs Framework to guide humane experimental techniques in animal studies and other research areas.

The Principles of Humane Experimental Technique, the 3Rs (Replacement, Refinement, and Reduction), have been the mainstay of humane research involving animals for over fifty years.

However, it is becoming...

In this episode of Listen In, learn more about how the convergence of AI technology and scientific discovery can revolutionize our understanding of biology and disease.

Generating insights into tissue microenvironments is crucial to our understanding of normal and abnormal tissue development, such as during cancer progression.

Spatial biology methods using microscopy and multiplexing techniques have allowed researchers to ...

Glycosylation is a prevalent modification of proteins known to play diverse roles across a wide range of biological processes.

While glycoproteins are widely recognized as key molecular features involved in human health and disease, the analysis of protein glycosylation has historically been hampered by a lack of efficient and simple methods to characterize the analytically challenging glycan structures. Examples include s...

Liquid chromatography-mass spectrometry (LC-MS) is a crucial technique in many life sciences, including proteomics, metabolomics, pharmaceutical analysis, clinical diagnosis, and forensic science.

In this episode of Listen In, elevate your analysis and liquid chromatography. Learn what consumables, materials, and reagents can harm your LC-MS data for more accurate quantification using perfluoroalkyl substances (PFAS) as an ...

Holotomography has emerged as a helpful tool for imaging live specimens without additional pre-treatment, such as fixation, fluorescence labeling, and excitation.

It can achieve long-term three-dimensional observations of live specimens for weeks without cellular damage caused by photoactivation. The high resolution (under 150 nm lateral) achieved through synthetic numerical aperture provides sufficient spatial information...

Buffers are critical to nearly all our experiments. Poorly prepared buffers lead to failed Western blots, poor protein yields, flat binding curves—and wasted time.

Understanding why you need buffers, knowing how to choose the right one, and troubleshooting buffer issues are fundamental skills you can apply to make all your experiments work better—and you only need to learn how to prepare them correctly once.

In this episode...

You have written a research paper. What now? Your research can only have an impact if someone reads it. So, you must submit your article to a journal for publication.

In this episode of Listen In, learn the nuts and bolts of scientific publication with a step-by-step tour of the whole process. Explore how to select the right journal and what tools are available to help make that decision. Plus, get advice on how to make th...

The best way to solve a problem is to avoid it in the first place. While journals can and do reject articles for scientific reasons, they also reject articles for structural issues. By taking a few simple steps, you can learn how to circumvent these difficulties for a smooth publication process.

In this episode of Listen In, we'll go through some of the structural reasons that scientific journals reject articles, how to sol...

All research papers have certain elements in common: Introduction, Methods, Results, and Conclusion. How can you structure your introduction to best frame the research question for your readers? Must the methods section read like a laundry list of reagents? Can you be dramatic in the results without losing objectivity? Is there any room in the concluding section to pose new conflicts?

In this episode of Listen In, we will ...

Rarely do we consider writing a scientific paper as a creative exercise. But what if that could change? The best way to communicate anything is through stories. The scientific process has all the elements inherent in storytelling: a rich background, a problem or conflict to solve, and a resolution.

In this episode of Listen In, we will reframe the writing process to help you clearly and concisely communicate your research ...

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases.

Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin gene to test an antisense olig...

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission at the ultrastructural level.

Neurons communicate at specialized junctions, or synapses, via chemical messengers called neurotransmitters. Within a millisecond of neuronal stimulation, synaptic vesicles packed with neurotransmitters fuse with the presynaptic p...

Experience the transformative power of unbiased, data-driven cell analysis with access to over 25 image-derived label-free parameters, empowering you to easily assess sample quality, optimize gating strategies, and validate rare events.

In this episode, learn how automated image analysis combined with flow cytometry can help improve data accuracy and precision, optimize and verify gating strategies, and discover novel biolo...

Organoids are three-dimensional in vitro cultures derived directly from patient tissues or induced pluripotent stem cells (iPSC) and embryonic stem cells. They self-organize to generate structures that resemble the tissue of origin and recapitulate the key physiological functions of the parental organ.

In this episode of Listen In, explore the benefits of organoids as infectious disease models and drug screening vehicles, ...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community. 

This episode of Listen In with Cristy Gelling explores image manipulation. Many common types of image manipulation are classified by journals as scienti...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community. 

This episode of Listen In with Karen O'Hanlon Cohrt explores publishing negative results and what is acceptable. Get answers to key questions, such as w...