Longevity Junky
TIME TO GET YOUR FIX! Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you’re a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world. Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist. Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky. They’re good friends and willing guinea pigs for all longevity-related experiments. From hallucinogens to full body MRIs, micro-dosing Cialis to tech, exercise, and diet to mindfulness, they’re on a voyage of discovery, meeting the best experts in each space, learning and sharing their experiences, and giving listeners actionable tips on how to live a longer, happier life. Let’s face it: reducing our biological age, extending our lifespan, and increasing happiness are pretty universally appealing ideas. Hosted on Acast. See acast.com/privacy for more information.
Episodes
Tinnitus isn’t just annoying—it’s a red flag for cognitive decline, poor sleep, and social isolation. Dr. Ben Thompson, founder of Treble Health, joins Nikki and Buck to expose the truth about hearing loss and brain aging. From phantom sounds to biohacks like pink noise, hearing aids, and neuromodulation, this episode unpacks the surprising science behind why your ears might be sabotaging your longevity—and what you can actually do...
Can forgiving others actually make you healthier? Dr. Robert Enright, the pioneer of forgiveness science, reveals how forgiveness transforms emotional and physical health. He breaks down the damaging effects of unforgiveness—like high blood pressure and anxiety—and explains how his four-phase forgiveness model is improving lives in schools and hospitals. From self-forgiveness to emotional resilience, this episode redefines forgiven...
Can stress be hacked with vibrations? Psychiatrist and neuroscientist Dr. Dave Rabin joins Nikki Leigh and Buck Joffrey to reveal how chronic stress disrupts health—and what you can do about it. From psychedelics to wearable tech like Apollo Neuro, Dr. Rabin explains how vibration therapy is being used to regulate the nervous system, boost emotional resilience, and support long-term mental health.
They dive into the latest neuro...
Women's health has been misunderstood—and often ignored—for decades.
In this episode, Dr. Pamela Peeke joins Buck Joffrey and Nikki Leigh to set the record straight. From the outdated belief that “women are just small men” to the shocking truth about flawed medical research, Dr. Peeke reveals what every woman needs to know about body composition, hormone therapy, emotional eating, and chronic stress. Her “Mind, Mouth, and Muscl...
Dr. Ryan Rosner went from the NFL to the lab—now he's advancing some of the most promising developments in aging science. In this episode, we talk about his transition into molecular aging research and the science behind hypoxia, plasmid therapy, and follistatin’s role in muscle and metabolic health.
We cover key topics including cellular resilience, epigenetic rejuvenation, gene therapy, and emerging applications of plasmid tec...
Welcome to Longevity Junky's inaugural trivia show, Longeopardy! First-time game show host Dr. Buck Joffrey is joined by contestants Nikki Leigh and Madisyn Shipman in a fun and informative game centered around health, wellness, and anatomy.
Follow Madisyn Shipman:
Instagram @madisynshipman
TikTok @itsmadisynshipman
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Let us know what kind of trivia topics you would like us to do next. Send us a message at:
www.longevityjunky...
What do you do when your husband cheats on you… while you’re battling cervical cancer?
Would you trust a babysitter who gave your toddler melatonin without asking?
And how far is too far when it comes to dietary boundaries?
In this episode of Longevity Junky, Nikki Leigh and Dr. Buck Joffrey unpack Reddit stories that expose the messy, complicated realities of health in everyday life.
From HPV-related cancer and kidney infectio...
What if you could slow aging, repair cells, and boost your brain—all by breathing oxygen under pressure?
Dr. Shai Efrati joins Longevity Junky to unpack the science and protocols behind hyperbaric oxygen therapy (HBOT). This isn’t just oxygen—it’s precision medicine. We dive deep into how HBOT enhances oxygen delivery to tissues, triggers cellular repair, and may even lengthen telomeres.
From cognitive enhancement to VO2 max ...
What if you could trigger the benefits of a 36-hour fast—without skipping a single meal? Dr. Chris Rhodes, nutritional biochemist and founder of Mimio, joins Nikki and Buck to unpack the science behind fasting mimetics. Discover how specific molecules can mimic the effects of prolonged fasting, from activating autophagy to improving insulin sensitivity, reducing inflammation, and suppressing appetite. Plus, we dives into weird well...
Dr. Sharon Bergquist—Harvard-trained physician, Emory researcher, and author of The Stress Paradox—joins Longevity Junky to flip the script on everything we thought we knew about stress. Discover how good stress (yes, it exists!) can supercharge your cellular health, build resilience, and even slow down biological aging. From cold exposure and intermittent fasting to emotional challenges that light you up, this episode explores the...
Can Alzheimer’s be reversed without drugs?
Dr. Dean Ornish says yes—and he has the clinical data to prove it. In this episode of Longevity Junky, Nikki and Buck sit down with the father of lifestyle medicine to explore a groundbreaking study showing how diet, exercise, stress reduction, and community can actually stop—or even reverse—early-stage Alzheimer’s. From the science of neuroplasticity to the power of social support, thi...
Get ready for some of the wildest, most jaw-dropping medical stories ever shared on Reddit. From ER scammers faking injuries for pain meds… to DIY tracheotomies, exploding intestines, and near-fatal sex injuries—these real-life cases are as unbelievable as they are horrifying.
Join Dr. Buck Joffrey and Nikki Leigh as they break down these totally unhinged Reddit stories with useful medical insights and some humor along the way.
<...What if preserving your body after death wasn’t science fiction—but science in progress?
In this mind-expanding conversation, James Arrowood of Alcor dives deep into the science and ethics of cryonics, explaining how ultra-cold preservation of human tissue could transform the future of medicine, organ banking, and even space travel. Learn how cryonics works, how Alcor operates as a non-profit, and what it means for our understan...
Discover how AI is revolutionizing personalized nutrition, diet tracking, and longevity in this episode of Longevity Junky. Caltech-trained physicist and AI entrepreneur Dr. Dmitriy Richard Starson reveals the tech behind his groundbreaking platform that analyzes your meals through photos and voice—no more tedious logging. Learn how AI can tailor your food choices, improve metabolic health, and even help doctors deliver better care...
Is boredom slowly killing you? Cognitive neuroscientist Dr. James Danckert joins Longevity Junky to break down the science of boredom—what it does to your brain, how it’s linked to depression, addiction, even heart disease, and why your response to boredom could affect your longevity. Plus, why some people shock themselves out of boredom (literally).
Learn more about Dr. James Danckert:
https://www.jamesdanckert.com/about
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Bio...
Did you know microplastics could be silently damaging your hormones, fertility, and heart health? In this explosive episode, Dr. Leonardo Trasande—NYU professor, bestselling author, and global leader in environmental pediatrics—joins Buck and Nikki to reveal how these invisible plastic particles are infiltrating our bodies through food, water, and even air. Learn how microplastics disrupt your endocrine system, spike inflammation, ...
What supplements do two longevity junkies actually take? In this episode, Dr. Buck Joffrey and Nikki Leigh reveal their personal daily supplement stacks—the real-life regimens they follow to stay sharp, healthy, and (hopefully) young forever.
But here’s the kicker… not all supplements on store shelves are what they seem. Buck shares the shocking results of a study revealing that nearly half of herbal supplements don’t even conta...
What if rethinking relationships could unlock deeper connection, emotional well-being, and even longevity? In this episode of Longevity Junky, Nikki and Buck sit down with Dr. Joli Hamilton—research psychologist, certified sex educator, and relationship coach—to explore the world of consensual non-monogamy, jealousy, and alternative relationship dynamics.
Dr. Joli shares her personal journey from monogamy to a cohabiting triad, ...
Oscar-winning screenwriter and five-time world champion triathlete—Lesley Paterson doesn’t just break barriers; she obliterates them. From pushing through brutal endurance races to fighting for All Quiet on the Western Front, her mindset is an absolute masterclass in resilience. We dive into her elite fitness strategies, how she overcame chronic Lyme disease, and the shocking connection between metabolic health and cancer.
Learn...
In this episode of Longevity Junky, Buck Joffrey and Nikki Leigh sit down with David Mark Dror, author of Investors in Longevity, to explore the multi-billion-dollar investments driving longevity breakthroughs. Discover how Jeff Bezos, Peter Thiel, and major biotech firms are funding research in:
- Gene therapy and cellular reprogramming to slow aging
- AI-driven drug discovery for life extension
- Regenerative medicine and st...
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