Mayo Clinic Talks

Host: Darryl S. Chutka, M.D.

Guests: Mary Lang; Caroline M. Gearin; Nick R. Winder, SPT

Students in the various fields of medicine deal with a variety of stresses. Perhaps one of the biggest stresses is getting accepted into their respective school to begin their training. Once enrolled, they’re then provided a large amount of information to be memorized and essentially need to learn a new language. They have pressure to do well on...

Host: Darryl S. Chutka, M.D.

Guest: Robert L. Scott, M.D., Ph.D.

Pulmonary hypertension is an important medical condition and often underrecognized in primary care. It has a variety of causes, and its most common presenting symptom is dyspnea. As primary care clinicians, we often see patients with symptoms of dyspnea and pulmonary hypertension is not a health problem we commonly encounter. Yet, early recognition and diagnosis is im...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Jewel J. Samadder, M.D., Gastroenterologist and Professor, Mayo Clinic

In this episode of Mayo Clinic Talks, Dr. Denise Dupras interviews Dr. Jewel Samadder about colon cancer, with a focus on how genetics and family history influence cancer risk and screening strategies. Dr. Samadder emphasizes empowering primary care providers to identify patients who may benefit from genetic evaluation ...

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP

Guest: Nicole Callahan, APRN, CNP, MS

In this episode, along with guest Nicole Callahan, APRN, CNP, MS, we explore reproductive health challenges. Starting with the different types of miscarriage—identifying their unique anatomic changes, symptoms, and outcomes. We will cover the basics of both female and male infertility, including when it’s the ideal time to ref...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Saad J. Kenderian, M.B., Ch.B.

Dr. Saad Kenderian discusses the use of CAR-T cell therapy, a groundbreaking treatment that genetically modifies a patient's T-cells to target and destroy cancer cells, particularly in blood cancers like leukemia and lymphoma. He highlights the importance of identifying eligible patients, monitoring treatment response, and applying genomics to guide the futur...

Host: Danielle O’Laughlin, PA-C, MS

Guest: Jenna Wygant, APRN, CNP, DNP

In this episode, Jenna Wygant, APRN, CNP, DNP, walks listeners through the most common types of vaginitis, helping providers to confidently differentiate between them.

We’ll explore the definitions, causes, risk factors, signs and symptoms, as well as diagnostic methods and treatment options for each condition. Comparing the features of these common vaginitis c...

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP

Guest: Jenna Johnson, APRN, CNP, DNP

In this episode, we focus on understanding and differentiating common vulvar conditions with guest Jenna Johnson, APRN, CNP, DNP. We will cover how to recognize conditions such as risk factors, signs and symptoms, and gain insight into how these conditions are diagnosed and treated. We’ll also highlight helpful ways to compare ...

Host: Danielle O’Laughlin, PA-C, MS

Guest: Jenna Wygant, APRN, CNP, DNP

Guest, Jenna Wygant, APRN, CNP, DNP, joins us to explore the full spectrum of contraception options - from natural family planning to non-hormonal and hormonal methods. For each type of contraception, an understanding of how each type works, their efficacy, and the potential risks and benefits will be covered. We also break down the different types of emergency...

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP

Guest: Jissy Cyriac, M.D.

In this episode, guest Jissy Cyriac, M.D., will walk us through the complexities of menstrual health by comparing a normal menstrual cycle with the key causes of abnormal uterine bleeding and menopause. Recognizing the signs, symptoms, and treatment options for conditions like endometriosis, adenomyosis, and endometrial hyperplasia. Plus,...

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP

Guest: Danielle O’Laughlin, PA-C, MS

In this episode, along with host/guest Danielle O’Laughlin, PA-C, MS, we will discuss benign, inflammatory breast conditions. We will cover how to differentiate between common issues such as mastitis, breast abscess, fat necrosis, galactorrhea, and gynecomastia. We’ll walk through the key signs and symptoms to watch for and exp...

Host: Darryl S. Chutka, M.D.

Guests: Cadman L. Leggett, M.D., and Chamil C. Codipilly, M.D.

Occasional heartburn from gastroesophageal reflux is usually nothing more than an occasional nuisance for most patients.  However, when the reflux becomes chronic, it can become more serious.  One complication is Barrett’s esophagus. On occasion, Barrett’s can develop into esophageal adenocarcinoma, an aggressive malignancy with a survival r...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Michael Zimmer, Ph.D., Director of Rare Diseases at Moderna Therapeutics

This episode of Genes & Your Health welcomes Dr. Michael Zimmer from Moderna Therapeutics, who discusses how mRNA technology is being applied to treat rare genetic diseases, especially liver-based metabolic disorders. Dr. Zimmer explains how mRNA can help the body produce missing proteins, the challenges of delive...

Host: Darryl S. Chutka, M.D.

Guest: John Haney, M.D., M.P.H.

Lung transplantation remains a very viable option for patients with end-stage pulmonary disease who no longer respond to medical management. Over 5,000 lung transplants are performed annually around the world. However, its estimated that over 10 times this number are candidates and awaiting a transplant. A shortage of organs remains the major limiting factor. What are the...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Heidi Nelson, M.D., Emeritus Chair of the Department of Surgery and past Chair of the Division of Colon & Rectal Surgery at Mayo Clinic in Rochester

Guest: Jaeyun Sung, Ph.D., Associate Professor of Biomedical Informatics and Senior Associate Consultant II in the Department of Quantitative Health Sciences, Mayo Clinic Rochester

This episode of Genes & Your Health presents the resul...

Host: Darryl S. Chutka, M.D.

Guest: Julie K. Heimbach, M.D.

In 2024, over 48,000 organ transplants were performed in the U.S., representing an increase over the number performed the year before. There was also an increase in the number of transplants performed internationally, offering hope to patients worldwide with organ failure. Significant advancements have been made in the field of organ transplantation, and this is responsibl...

Host: Darryl S. Chutka, M.D.

Guest: Rohan M. Goswami, M.D.

The benefits of artificial intelligence or AI are just beginning to be recognized. AI has the potential to improve productivity and efficiency in the workplace, reduce errors and help sort out complex issues. The field of healthcare is finding roles for AI by improving the management of patient data, enhancing clinical decision making and assisting in medical imaging analys...

Host: Darryl S. Chutka, M.D.

Guest: Ruben J. Crespo-Diaz, M.D., Ph.D.

The world’s first human-to-human heart transplant was performed in 1967 and represented a significant breakthrough for medical science. Although the transplant patient only survived 18 days, it was still a historic event. Since this initial heart transplant, significant improvements have been made in the field of organ transplantation and currently, approximately...

Host: Darryl S. Chutka, M.D.

Guests: Nitin N. Katariya, M.D., and Lavanya Kodali, M.B.B.S., M.D.

At this time, about 11% of the population in the U.S. has diabetes.  This represents nearly 40 million people. And this number is increasing, not only in the U.S. but around the world. Although we have more medical options now than ever before for managing diabetes, the treatment is less than optimal. Another option is a pancreas transp...

Host: Darryl S. Chutka, M.D.

Guest: C. Burcin Taner, M.D.

Recently, the criteria for organ donors have expanded in order to address the increasing difference between the number of available organs and the demand for transplants. Advancements in medical technology, a better understanding of transplant immunology, and the improvement of transplant surgery techniques have allowed for the inclusion of a greater pool of donors with vari...