Mayo Clinic Talks

Host: Darryl S. Chutka, M.D.

Guest: Stacy D. D’Andre, M.D.

When we diagnose a patient with cancer, we typically focus on finding the most effective treatment for that malignancy: surgery, radiotherapy, chemotherapy, or immunotherapy. However, to a patient, the diagnosis of cancer means much more. Patients commonly experience fear and anxiety just from receiving the diagnosis. Other symptoms may include insomnia, depression, pain, a...

Host: Darryl S. Chutka, M.D.

Guest: Melinda J. Hahm

Bariatric surgery is very likely the most effective method for long-term weight loss. It’s not unusual for patients to lose well over 50% of their excess body weight. As a result, a variety of chronic health risks are reduced including diabetes, cardiovascular disease, sleep apnea, hypertension to name just a few. Exercise, associated with bariatric surgery is important to help ac...

Host: Darryl S. Chutka, M.D.

Guest: Eric J. Moore, M.D.

Salivary gland tumors can be benign or malignant, as well as primary or metastatic. Malignant salivary gland tumors usually present after the 6th decade, whereas benign lesions tend to occur a bit earlier, usually in the 4th to 5th decades. An interesting statistic is that the vast majority of salivary gland tumors occur in the parotid, only about 10% occur in the submandibula...

Host: Darryl S. Chutka, M.D.

Guest: Sunanda V. Kane, M.D.

Most people who develop inflammatory bowel disease are diagnosed before the age of 30. In women, this often occurs during the middle of their reproductive years. Some with inflammatory bowel disease choose to avoid pregnancy, usually due to misconceptions about pregnancy risks. Yet if properly managed, women can experience a normal, uneventful pregnancy and deliver a healthy...

Host: Darryl S. Chutka, M.D.

Guests: Amanda M. Johnson, M.D., and Victor G. Chedid, M.D., M.S.

This podcast continues our series on inflammatory bowel disease. The topic is important and timely: “Inflammatory Bowel Disease in Special Populations: The Elderly, the Obese and the LGBTQ Patient.” It’s critical that we broaden our perspective in addressing the unique challenges faced by these often-unrecognized population groups. How co...

Host: Darryl S. Chutka, M.D.

Guest: Konstantinos A. Papadakis, M.D.

Due to the complexity and new pharmacologic options for the management of inflammatory bowel disease, patients often have their care provided by a gastroenterologist. They may not see their primary care provider as often as in the past and some of their preventive health maintenance may not get performed. Are patients receiving primarily specialty care still receiv...

Host: Darryl S. Chutka, M.D.

Guests: Darrell S. Pardi, M.D., and Laura E. Raffals, M.D.

Pouchitis is a relatively common complication in patients who have ulcerative colitis and have had a proctocolectomy with an ileal pouch-anal anastomosis. It represents inflammation of the ileal pouch and symptoms may include increased stool frequency, cramps, fecal urgency and occasionally bloody stools. The diagnosis is usually suspected from ...

Host: Darryl S. Chutka, M.D.

Guests: Darrell S. Pardi, M.D., and Laura E. Raffals, M.D.

Microscopic colitis is one of the lesser-known members of the inflammatory bowel disease family. Symptoms include chronic, frequent diarrhea and fecal urgency. It’s usually suspected from the patient’s clinical symptoms and diagnosis is established by colonoscopy with biopsy. Biopsy is necessary as the colonic mucosa appears normal at endoscopy....

Host: Darryl S. Chutka, M.D.

Guest: Edward V. Loftus JR, M.D.

Inflammatory Bowel Disease is somewhat of an umbrella term for a group of chronic inflammatory conditions of the GI tract. The most common types include ulcerative colitis and Crohn’s Disease. While there are similarities between the two, there are also differences. For many individuals with inflammatory bowel disease, it’s only a mild illness. Unfortunately for some, it...

Host: Darryl S. Chutka, M.D.

Guests: David H. Bruining, M.D., and Nayantara Coelho-Prabhu, M.B.B.S.

An early diagnosis of inflammatory bowel disease is important in preventing long-term complications. Prompt treatment can improve quality of life, reduce the likelihood of hospitalizations, and help maintain remissions. However, establishing a diagnosis is often challenging due to the nonspecific and fluctuating nature of symptoms. I...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Melissa Davis, Ph.D., Director of the Institute of Translational Genomic Medicine at Morehouse School of Medicine

In this insightful episode, Dr. Melissa Davis delves into the profound influence of genetic ancestry on health outcomes and disparities. Her pioneering work in disparities genomics sheds light on how biological determinants intersect with systemic marginalization to exacerbate ...

Host: Darryl S. Chutka, M.D.

Guests: Jesse D. Bracamonte, D.O., Casey Martinez, Kiyan Heybati

If you’re a physician, there are several events during your medical journey that you’ll always remember, receiving your letter of acceptance for medical school, medical school graduation and Match Day. For those of you who aren’t physicians, Match Day is a very exciting day for medical students. It represents the day students learn where t...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: John R. Giudicessi, M.D., Ph.D.

Dr. Giudicessi, a leader in cardiovascular genetics and gene therapy research, discusses the latest advancements in understanding and treating genetic arrhythmias and cardiomyopathies. This episode provides a comprehensive look at how genetics is revolutionizing cardiovascular care, empowering physicians to offer more precise, patient-centered treatments. Dr...

Host: Darryl S. Chutka, M.D.

Guest: John W. Wilson, M.D.

Tuberculosis remains a significant health concern. Globally, in 2023, an estimated 10 million individuals developed active tuberculosis and over one million died of the disease. In the U.S., just under 10, 000 individuals in the U.S. were diagnosed with TB, representing an increase over 2022. While tuberculosis remains a treatable disease, it’s important to susp...

Host: Darryl S. Chutka, M.D.

Guests: Mary Lang; Caroline M. Gearin; Nick R. Winder, SPT

Students in the various fields of medicine deal with a variety of stresses. Perhaps one of the biggest stresses is getting accepted into their respective school to begin their training. Once enrolled, they’re then provided a large amount of information to be memorized and essentially need to learn a new language. They have pressure to do well on...

Host: Darryl S. Chutka, M.D.

Guest: Robert L. Scott, M.D., Ph.D.

Pulmonary hypertension is an important medical condition and often underrecognized in primary care. It has a variety of causes, and its most common presenting symptom is dyspnea. As primary care clinicians, we often see patients with symptoms of dyspnea and pulmonary hypertension is not a health problem we commonly encounter. Yet, early recognition and diagnosis is im...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Jewel J. Samadder, M.D., Gastroenterologist and Professor, Mayo Clinic

In this episode of Mayo Clinic Talks, Dr. Denise Dupras interviews Dr. Jewel Samadder about colon cancer, with a focus on how genetics and family history influence cancer risk and screening strategies. Dr. Samadder emphasizes empowering primary care providers to identify patients who may benefit from genetic evaluation ...

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP

Guest: Nicole Callahan, APRN, CNP, MS

In this episode, along with guest Nicole Callahan, APRN, CNP, MS, we explore reproductive health challenges. Starting with the different types of miscarriage—identifying their unique anatomic changes, symptoms, and outcomes. We will cover the basics of both female and male infertility, including when it’s the ideal time to ref...

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Saad J. Kenderian, M.B., Ch.B.

Dr. Saad Kenderian discusses the use of CAR-T cell therapy, a groundbreaking treatment that genetically modifies a patient's T-cells to target and destroy cancer cells, particularly in blood cancers like leukemia and lymphoma. He highlights the importance of identifying eligible patients, monitoring treatment response, and applying genomics to guide the futur...