MedEvidence! Truth Behind the Data
Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com
Episodes
Urologist and president of the Duval County Medical Society Dr. Ali Kasraeian joins Dr. Michael Koren to update us on recent advances in Urology. In Part 1 of this series, Dr. Kasraeian talks about his journey, from growing up in a medical family to becoming a urologist and healthcare advocate with a passion for innovative approaches to prostate cancer treatment. Part 1 highlights how mentorship, family influence, and...
Dr. Michael Koren sits down with Dr. Murali Ramaswamy to explore the concept of Research as a Care Option. They compare this with the misconception of research as a treatment option to reveal how clinical trials provide structured environments that often lead to better health outcomes regardless of the specific intervention. They debunk the idea that clinical trials provide treatment, due to the randomized nature of t...
Dr. Michael Koren joins Kevin Geddings to discuss how tariffs could significantly impact pharmaceutical prices. They talk about how barriers to import may affect both prescription and especially over-the-counter medication prices. They move onto the difficulty of starting new drug manufacturing in the US and how clinical trials may provide relief for some patients.
On this episode, recorded in front of a live audience, Cardiologist Dr. Michael Koren is joined by pulmonologist Dr. Mitchell Rothstein to discuss Chronic Obstructive Pulmonary Disease (COPD). COPD is obstruction of the lungs, making it hard to breathe and represents a significant health challenge . It affects millions of Americans and is a leading cause of mortality, yet receives disproportionately low research fundi...
Dr. Michael Koren Join Kevin Geddings to reflect on the evolution of medical research ethics from the troubling practices at Willowbrook Hospital in the 1970s to today's patient-centered approach. He connects this progression to John Lennon and Yoko Ono's final major concert, which raised awareness about conditions at the hospital while highlighting how far ethics in clinical trials have advanced.
Dr. Michael Koren shares insights from his presentation at the American College of Cardiology meeting in Chicago about a groundbreaking oral PCSK9 inhibitor that could lower cholesterol by 80% when combined with a statin. The development represents a significant advancement in treatment options for the 20% of patients who don't respond adequately to statins alone or experience statin intolerance. They also chat a...
Psychiatrist Dr. Rachna Saralka joins Cardiologist Dr. Michael Koren to explore the emerging field of artificial intelligence in psychology. They discuss the promise and shortfalls of using AI in this field, and the need for hard data and validated results through clinical trials. They get into empathy, the placebo effect, and potential use of AI to train psychologists and other doctors just like chess bots can help ...
On this Monday Morning Minute, Dr. Michael Koren draws parallels between the NCAA Final Four basketball tournament and the clinical research process. He explains that in medicine, researchers start with literally 10,000 potential molecules, which get whittled down to only three or four medications to be tested in big, phase III clinical trials. This ensures that only the most promising medical technologies get approve...
Judith Abbey, DNP, shares her journey from medical student in Ghana to healthcare entrepreneur in Florida, where she founded On the Go Drip, a mobile IV therapy service delivering treatments directly to patients' homes. Dr. Michael Koren asks her about her history and business, and the two of them dive into some of the controversy surrounding supplement treatments.
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Cardiologist Dr. Michael Koren joins Kevin Geddings to discuss progress in the world of cholesterol management. Dr. Koren explains the importance of getting cholesterol - especially LDL cholesterol - under control and the potential benefits to heart attack and stroke risk. They discuss some of the problems with current therapies; they are highly effective but can introduce burdens to patients with the back-and-forth f...
On This week’s episode, Dr. Michael Koren Interviews local media entrepreneur Randall Thomas, host of PB and Jax. They discuss how “The Internet is a Weird Place.” They examine the algorithms, platforms, and biases that make up our experience on the internet. Mr. Thomas explains how the algorithms determine what gains traction and that all a creator can do is hope to increase their chances of something going viral. Th...
Ken Amaro, a former broadcaster with 42 years of experience and current Jacksonville City Councilman for District 1, joins Eric Ross, RN. Ken shares his decade-long journey with Type 2 diabetes from diagnosis through management and lifestyle adaptations, dropping motivational nuggets and tips he's learned along the way. The two discuss the need for regular checkups, the importance of listening to your body, and t...
On this week's Monday Morning Minute, Dr. Michael Koren joins Kevin Geddings to answer the question "can I participate in clinical trials even if I'm not sick?" They discuss how having "healthy participants" is critical for some clinical trials. They look at a current study that examines how the body processes oral statin medications and if those with kidney disease process medicine in a ...
In this episode, Dr. Michael Koren is joined by Dr. Sunil Joshi, the Chief Health Officer of the city of Jacksonville, Florida. Dr. Joshi runs through five health initiatives to lower the premature death rate in the city and county. The doctors discuss health inequalities, the social and economic factors that contribute to negative health outcomes, and the pioneering efforts of the city's Chief Health Officer.
This week Dr. Koren Joins Kevin Geddings for the Monday Morning Minute to talk about a clinical research procedure to resurface a part of the digestive system that contributes to obesity and diabetes. This program is currently being studied in northeast Florida. Dr. Koren explains how the device works, it's expected results, and how you can learn more and potentially join this area of study.
Dr. Trevor Greene joins Dr. Michael Koren to discuss the effects of inflammation on the cardiovascular system. The two cardiologists talk about biomarkers that have increasing importance: including liporprotein(a) and hsCRP. The doctors finish up with actionable lifestyle changes everyone can implement.Â
Koren's Key Takeaways:
- Inflammation plays a big role in the body
- Chronic inflammation influences ca...
Most pills are taken daily, and many vaccines protect for around a year, but could medical device products last even longer? In this episode of the Monday Morning Minute, Dr. Michael Koren joins Kevin Geddings and explains what medical devices are and how they can make long-term differences for patients. The two discuss device treatments for diabetes, weight loss, atrial fibrillation, blood pressure, and how AI may be...
Anesthesiologist Dr. Todd Bertoch speaks with Dr. Michael Koren in this exciting episode about the a new pain medication, Journavx (suzetrigine), which was just approved by the FDA in January, 2025. The doctors discuss this breakthrough pain management medication, its safety profile, side effects, and how it compares to NSAIDs, acetaminophen, and opioids. They also dive into the approval process, how trials were condu...
Kevin Geddings talks with Cardiologist Dr. Michael Koren about the health risks and benefits of alcohol, which continue to be significant topics of discussion in health circles. This episode delves into a late Biden-era proposal for alcohol warning labels amid growing concerns about cancer risks associated with consumption. Dr. Koren expresses a desire for more clinical trial data on this subject looking at the health...
Rheumatologist Dr. Manish Jain joins Cardiologist Dr. Michael Koren as they discuss how performing clinical trials can help physicians become more holistic and knowledgeable, and how the process can result in better care for patients. In this conversation, the principal investigators explore Dr. Manish's journey as a clinician and investigator, including how he learned to approach patients about research, underst...
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