Metascience Matters

Metascience Matters

I'm Randy Ellis, a computational biologist and neuroscientist who cares about rigor in science. I started Metascience Matters to spread awareness about systemic issues that slow the progress of science for the purpose of fixing them. Views are my own. If you are a metascientist, I want to talk to you.

Episodes

May 27, 2026 54 mins

Alexander Gibson is a PhD student at the Queensland University of Technology and the Australian Centre for Health Services Innovation studying the intersection of metascience and clinical machine learning. One of his focus areas is data provenance, the Who, What, Where, When, Why, and How of datasets, and how neglecting this can lead to bad outcomes in medical machine learning not only in research, but also for clinical practice an...

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Charles Piller, an Investigative Correspondent for Science Magazine, is the author of the 2025 book Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's. He has received more than 40 honors or awards from American Association for the Advancement of Science/Kavli Foundation, National Institute of Health Care Management, Society of Professional Journalists, National Academies/Eric and Wendy Schmidt, Los Angeles Pr...

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Tim Errington is the Senior Director of Research at the Center for Open Science. He led the Reproducibility Project: Cancer Biology, Systematizing Confidence in Open Research and Evidence (SCORE), as well as the implementation and evaluation of initiatives such as Registered Reports, Registered Revisions, responsible conduct of research trainings, and open science badges.


CONTACT RANDY:

Feedback:

metasciencematters@gmail.com


EPISODE L...

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Brian Nosek is the cofounder and Executive Director of the Center for Open Science. He co-developed the Implicit Association Test, a method that advanced the study of implicit bias. He then co-founded three non-profit organizations: Project Implicit to advance research about implicit bias, the Society for the Improvement of Psychological Science to improve the research culture in his home discipline, and the Center for Open Science...

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Eugenie Reich is an attorney committed to taking on scientific fraud, understanding the incentives that drive it, and recovering misdirected research funding. She is also a former investigative science journalist committed to correcting the scientific record. Her 2009 book Plastic Fantastic, details a major fraud cause in physics at Bell Labs. Two of the cases she has litigated cases were against Biogen ($900 million settlement), a...

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James Heathers is the Founder and Director of the Medical Evidence Project, a venture of The Center for Scientific Integrity. He aims to reduce medical harm and improve patient outcomes by identifying and publicizing errors and miscondcut in the medical literature. He uses forensic meta-analytical techniques to detect and deconstruct errors arising from low-quality science and fraudulent work in areas that involve large numbers of ...

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Mu Yang is a behavioral neuroscientist at Columbia University, and a scientific sleuth responsible for more than 300 retractions. She led an effort that discovered more than 130 fraudulent papers in the publication record of Eliezer Masliah, former head of the Division of Neuroscience at the National Institute on Aging at the National Institutes of Health. Her sleuthing work has been documented in the book "Doctored" by Charles Pil...

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Florian Naudet is a Professor of Therapeutics at Rennes University. As a metascientist and psychiatrist, his research interests lie in developing and evaluating methodological solutions to treatment assessment, primarily but not exclusively for mental health conditions. His work has also made inroads to quantifying and understanding research waste and the prevalence of substandard data-sharing practices.


CONTACT RANDY:

Feedback: meta...

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Chirag Patel is an Associate Professor of Biomedical Informatics at Harvard Medical School, renowned for his expertise in using computational methods to understand human health and disease from high-throughput data streams. He specializes in understanding the role in the intersection of genetics and environmental exposures (the exposome) in human health, as well as various disease areas such as diabetes, cardiovascular disease, and...

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