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October 5, 2025 15 mins

GLP-1 drugs like Ozempic, Wegovy, and Mounjaro have become a cultural phenomenon, transforming appetite regulation and weight loss like nothing before. But with their rise comes a flood of imitators, from flashy “GLP-1 patches” to supplements like Calocurb, all promising the same results without the needles or prescriptions. In this episode, I break down what GLP-1 actually is, how these drugs work, and why they’re so effective—not just for weight but also for cardiovascular outcomes. Then I take a closer look at the patches (spoiler: marketing magic, not science) and Calocurb’s hops extract, which shows some early promise but lacks long-term data. If you’re curious about food noise, appetite regulation, and how to separate science from sales tactics, this one’s for you.

Highlights:

  • How GLP-1 drugs regulate appetite, cravings, and even food noise
  • Why “GLP-1 patches” are all marketing and no science
  • What Calocurb is, how it works, and the research behind it
  • Short-term vs long-term evidence for appetite control

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