Episode Transcript
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Speaker 1 (00:04):
Welcome to More Than
Medicine, where Jesus is more
than enough for the ills thatplague our culture and our
country.
Hosted by author and physician,dr Robert Jackson, and his wife
Carlotta and daughter HannahMiller.
So listen up, because thedoctor is in.
Speaker 2 (00:25):
Welcome to More Than
Medicine.
I'm your host, dr RobertJackson, bringing to you
biblical insights and storiesfrom the country doctor's rusty,
dusty scrapbook.
Today we're going to take upwhere we left off last week,
talking about repurposed drugsfor the treatment of cancer.
We're reviewing the monologueCancer Care by Dr Paul Merrick.
(00:49):
I might add that Dr Merrick isone of the most highly published
physicians in the United Statesand I have a great deal of
respect for Dr Merrick and Ihave much appreciated following
his research during the COVIDcrisis and I very much
appreciate the monologue that heproduced on Cancer Care.
(01:12):
And, just so you know, thereare over 800 footnotes in the
Cancer Care monologuedocumenting the research that
was put into this monologue andlast week we talked about some
of the statistics on cancer thefinances that are put into
(01:33):
cancer treatment.
We talked about the genetictheories regarding cancer cause
and the metabolic concept ofwhat causes cancer and how we
can treat cancer withnutritional therapy and
repurposed drugs.
Well, today what I want to dois I want to give a summary of
(01:57):
repurposed drugs for treatingcancer, and the way this is
arranged by Dr Merrick is he hasthree tiers of repurposed drugs
.
The first tier is those with astrong recommendation.
I'm not going to talk abouttier two or tier three, because
their recommendations are weakerand we just really don't have
(02:20):
time to discuss them.
The tier one drugs have strongevidence for their effectiveness
and I'm going to list them foryou and then we're going to come
back and talk about themindividually.
The medications in tier oneinclude vitamin D3, melatonin,
(02:41):
green tea, catechins, metformin,curcumin, mabindazole, omega-3
fatty acids, berberine,atorbistatin, dysulfuram,
symetidine, mistletoe andsildenafil.
So these are the ones that arein the tier one list and these
(03:04):
have strong recommendations, solet's talk about these
individually.
Vitamin D3 has a very strongrecommendation for treating not
only cancer but also heartdisease and, as I told you last
week, probably 60% of mypatients whom I measure their
(03:27):
vitamin D level will bedeficient.
Normal is considered 30nanograms per milliliter, and
it's not unusual for my patientsto be in the 20s or even the
teens when I measure them.
When they're that deficient, mypatients often complain of
fatigue and sometimes musclepain or muscle cramps, and once
(03:50):
I provide them with adequatesupplementation, the fatigue
improves, the muscle crampsimprove, but it often takes
three months or more for thosesymptoms to abate and for the
vitamin D level to become 30 ormore.
Dr Marek recommends a level of50 to 70 for cancer prevention
(04:15):
and 70 to 90 in patients whoactually have cancer.
So achieving those levels canbe somewhat difficult.
The treatment level I mean thetreatment dose is 50,000 IUs
weekly, with a loading dose ofas much as 100,000 or 200,000 to
(04:39):
get the ball rolling.
So vitamin D deficiency hasbeen demonstrated to increase
the risk of breast cancer andother cancers as well, such as
Hodgkin's lymphoma, colon cancer, pancreatic, prostate, ovarian
and other cancers, and patientsare more likely to die from
(05:01):
those cancers if their vitamin Dlevel is deficient as compared
with people who have normal orsuper normal levels of vitamin D
.
Studies that measure thevitamin D level suggested
achieving vitamin D levels of 80would reduce cancer incidence
(05:24):
rates by as much as 70%.
So it's very important to tryto get those vitamin D levels up
as high as possible.
So what kind of cancers can betreated by vitamin D's levels
that are 70 to 90?
(05:45):
The studies show that it'sbeneficial, particularly in
patients with breast cancer,colorectal, gastric, esophageal,
lung and prostate cancers, aswell as those with lymphomas and
melanomas.
All right, so there we go.
That's your vitamin D.
Second one he recommends ismelatonin.
(06:07):
We talked a little bit aboutmelatonin last week.
So low melatonin levels havebeen implicated in the etiology
of certain or the cause ofcertain cancers.
Disruption of nocturnalmelatonin secretion and night
shift workers has beenassociated with a modestly
increased risk for breast andother cancer types.
(06:32):
Melatonin exerts cytotoxic,anti-mytotic and pro-apoptotic
actions in breast cancer cells.
That word apoptotic means todestroy the cell or cause the
cell to implode.
In addition, melatoninactivates cancer cell apoptosis
(06:55):
there's that word again wherethe cell implodes.
So melatonin activates cancercell implosion or destruction.
So there's the benefit ofmelatonin.
And melatonin also inhibits theproliferation of cancer stem
cells.
So you see there's multiplebenefits of melatonin.
(07:18):
So what kind of cell cancersdoes melatonin work against?
Melatonin is beneficial forbreast cancer, ovarian pancreas,
liver, kidney, oral stomach,colon, rectum, brain, lung,
prostate, head and neck andvarious leukemias and sarcomas.
(07:41):
So there you go.
There are multiple cancers thatcan respond to melatonin.
Now how do you take melatonin?
You need to start with a verylow dose, like one milligram,
use the slow release version andthen gradually increase the
dose Is best taken one hourbefore going to bed and you can
(08:04):
increase the dose up to 20 or 30milligrams if you want to.
You can't overdose on melatonin.
If you increase the dose tooquickly you might experience
nightmares.
So you have to be careful withgoing up on the dose.
You have to do it slowly.
So there's the dosing and thebenefit of melatonin.
(08:28):
So now let's talk a little bitabout green tea.
Green tea is epigallicatechingallate epigallicatechin gallate
it's abbreviated EGCG.
Now, green tea catechins havebeen proven to be effective in
(08:49):
inhibiting cancer growth inmultiple different ways.
So it is especially good ifit's combined with
phytochemicals like resveratrol.
And I'm not going to go intoall the ways that it works
because it's a littlecomplicated and it's just.
If you're a biochemist or amedical personnel, I would
(09:13):
encourage you to read Dr Marixmonologue, because he goes into
a great deal of detail about howthe green tea catechins
actually work in preventingcancer cell growth and spread.
So what are the cancers thatgreen tea catechins work for?
(09:34):
They're effective against arange of tumors, including
prostate, breast, uterus,ovarian, colorectal, gliomas,
liver and gallbladder, melanomaand lung cancers.
They're particularly beneficialfor prostate cancer and breast
cancer.
(09:54):
So how do we dose green teacatechins?
They should be taken in a doseof 500 to 1000 milligrams once a
day with food or after a meal,but not on an empty stomach.
It's rarely been associatedwith liver toxicity, so you have
to do this in conjunction withyour family doctor and you have
(10:16):
to monitor your liver enzymes.
Even though it's rare, it'sstill wise to check your liver
enzymes, and if you've gotunderlying liver disease, it's
probably not a good idea to usethe green tea extract.
All right, the next one on thelist is metformin.
(10:37):
There are multiple trials thatshow that taking metformin
inhibits the development ofcancer cells and reduces cancer
cell proliferation.
Now metformin, as you know, isused for treating diabetes and
PCOS, and so there's multipleuses for metformin, not just
(10:59):
treating diabetes.
It also helps with treatinginsulin resistance, which is
important for treating people bya nutritional metabolic pathway
who have cancer.
And metformin is beneficial fortreating multiple types of
(11:19):
cancers, for example, breastcancer, pancreatic, gastric,
colorectal, endometrial,pancreatic, prostate, non-small
cell lung cancer and bladdercancers.
The greatest benefit may be inpatients with colorectal and
prostate cancer, particularlywhen used as an adjunctive
(11:42):
therapy.
So how do we dose it?
A dose of metformin of 1,000milligrams twice a day is the
suggested dose.
It's a remarkably safe drugwith very few side effects.
The most common adverse effectis stomach cramps or loose
stools, sometimes coughs,sometimes hoarseness, sometimes
(12:04):
decreased appetite, and so youneed to take this in conjunction
with your family doctor.
And but it is a very effectiveanti-tumor slash, anti-cancer
medication.
The next tier, one drug withgood medical evidence for
(12:25):
anti-cancer activity is curcumin, popularly called curry powder
or turmeric.
It's a polyphenol extract fromcurcuma longa, curcuma longa.
It has antioxidant,anti-inflammatory,
anti-microbial, anti-viral andanti-cancer properties.
(12:50):
Now, isn't that amazing thatthe one compound can have all of
those benefits?
And I won't go into all thethings that, all the anti-cancer
mechanism and there arenumerous, about seven different
anti-cancer mechanisms thatcurcumin has, and the monograph
(13:14):
goes into all of those in greatdetail and it's just too much
for our discussion.
But what kind of cancers is itbeneficial for?
Cholorectal, lung, pancreas,breast, prostate, chronic
myeloid leukemia, liver, gastricbrain, ovarian skin, head and
neck lymphoma, esophageal cancerand myeloma.
(13:38):
This product, curcumin, hasbeen characterized as generally
safe by the US Food and DrugAdministration.
No toxicity is seen for dosesup to eight to 10 grams per day.
However, diarrhea can be afrequent side effect, especially
if the daily dose exceeds fourgrams.
A patic injury hepatitis is arare complication and therefore
(14:04):
liver function tests should bemonitored during long term use.
So there you have it.
You need to watch out for that.
One other caveat is it doeshave some anticoagulant effects
and may prolong bleeding inpeople using anticoagulant.
So if you're on xarelto oreloquus or cumudin, you need to
(14:26):
be careful if you're consideringtaking curcumin.
Now what about mobindazol?
That's a big one.
Many of you have heard JoeTippin's story or read about it
on the internet.
He had a non small cell cancerof the lung.
Joe Tippin took mobindazol andI think he took a few other
(14:47):
things along with it, or atleast he's added some things to
his current protocol that herecommends, but he overcame non
small cell cancer of the lungtaking mobindazol.
So mobindazol is anantiparasite drug and it has
multiple ways that it works, andit works very well against
(15:12):
multiple cancers, including nonsmall cell lung cancer,
adenocortical colorectalchemoresistant melanoma,
glioblastoma multiforme, whichis a brain cancer, colon
leukemia, osteosarcoma, softtissue sarcoma, acute myeloid
(15:34):
sarcoma, breast cancer, kidneycancer and ovarian carcinoma.
All of these have been shown tobe responsive to benzimidazols,
which is what mobindazol is.
So what are the dosing?
The suggestion from thismonograph is 100 to 200
milligrams a day.
(15:55):
The cost of mobindazol in theUS is skyrocketed, but you can
obtain this on the internet forabout $60 a month, and I
actually purchased some recentlyfrom Europe for about $60.
So what about omega-3 fattyacids?
(16:16):
Well, omega-3 fatty acids is agroup of polyunsaturated fatty
acids which contain a doublecarbon bond at the third carbon
atom from the methyl end of thecarbon chain.
Was that more than you neededto know?
So you know, there have been alot of studies that have
(16:38):
addressed the therapeuticeffects of omega-3
polyunsaturated fatty acidsagainst different human diseases
, such as cardiovascular andneurodegenerative disease and
cancer, and these studies havedemonstrated the clinical
utility and safety of thesenatural occurring substances.
(17:01):
Furthermore, more recently,omega-3 fatty acids have been
demonstrated to improve theoutcome against certain types of
cancer, improve the efficacyand tolerability of chemotherapy
and improve quality of life.
It also improves the catexia,or the loss of appetite and
(17:22):
weight loss.
That goes along with cancer.
Now there's a long discussionof why these things work and I'm
not going to go into that.
You just need to read themonograph.
So what are the types of cancerthat omega-3 fatty acids may be
beneficial for?
Breast cancer, colorectalcancer, leukemia, gastric cancer
, pancreatic cancer, esophagealcancer, prostate cancer, lung
(17:47):
cancer, head and neck cancer.
And the monograph givesdocumentation for all of these
claims, and I don't have time toread the documentation.
You'll have to read themonograph.
What are the dosing?
The suggested dose is 2 to 4grams of omega-3 fatty acids
(18:07):
daily.
These fatty acids may increasethe risk of bleeding and should
be used cautiously in patientswho are taking some kind of
anicoagulant.
The last one I'm going to.
Well, I got two more I want totalk about and then we're going
to have to wrap it up due totime.
Burberry Everybody asks me aboutburberry.
They come in my medical officeand ask about burberry.
(18:30):
Burberry and metformin can beused together, but you have to
be careful because burberry canlower your blood sugar and you
may have to use these onalternating months because of
that very reason.
Burberry is useful for multipledifferent cancers, such as
breast, lung, gastric liver,colorectal, ovarian, cervical
(18:52):
and prostate cancers.
There are some randomizeddouble-blind studies that
demonstrate that burberry in adose of 300 milligrams twice
daily significantly reduced therisk of recurrent colorectal
adenomas following polypectomy.
So a daily dose of 1,000 to1,500 milligrams usually taking
(19:15):
500 milligrams two or threetimes a day is suggested.
It doesn't really producehypoglycemia, but they still
recommend you should check yourblood sugar and monitor it
carefully.
Berberine should not be taken inpatients taking cyclosporine,
which is an immunosuppressivedrug, as that combination will
(19:37):
increase cyclosporine levels.
So that's an absolutecontraindication.
So, like I said, this is one ofthose medicines that you should
take in conjunction with theadvice of your family doctor.
The last one I'm going to talkabout is atorbastatin or
simbastatin.
Now, these are statin drugsthat doctors prescribe for
(20:00):
cholesterol management, andthere are multiple clinical
studies that show that statindrugs are effective in treating
multiple different cancers andreducing cancer-related
mortality.
In those who are taking statins, all cause mortality compared
(20:22):
to non-users is significantlyimproved.
The types of cancers that itmay be beneficial for is breast,
prostate, colorectal,hepatocelular, lung, testicular,
pancreatic, gastric, ovarianleukemia, brain and even kidney
cancers.
So there you go.
(20:43):
I think we're fixing to run outof time, but I just want to
recommend to you the monographby Dr Marrick.
I found it to be fascinating.
I couldn't put it down.
I read through the wholemonograph as quickly as I could,
and there was lots ofinformation in there that I
would not have been able toobtain really anywhere else.
(21:06):
My patients come to see mewanting alternative modes of
treatment for cancer.
I tell them honestly that thesetreatment protocols and these
repurposed drugs recommended byDr Marrick are to be taken in as
an adjunctive protocol totraditional chemotherapy.
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He doesn't recommend these asstandalone therapies.
I understand that some of mypatients are cynical and jaded
as regard to many traditionalmedical therapies, including
traditional chemotherapy, but DrMarrick is not recommending the
repurposed drugs as standalonetherapies.
(21:50):
He recommends them as an add-onto chemotherapy or radiation.
Patients have to make their ownindividual decisions about what
kind of therapy they want.
Many of these repurposed drugsrequire a family doctor's advice
and recommendations.
There are caveats with some ofthese medications, and so you
(22:13):
need to find a family doctor whounderstands these medications
and can help guide you along theway.
All right, well, that's all wehave for today.
I appreciate your listeningears and I pray that the Lord
will bless you.
Real good, I'll see you againnext week.
Speaker 1 (22:34):
Thank you for
listening to this edition of
More Than Medicine.
For more information about theJackson Family Ministry, dr
Jackson's books or to schedule aspeaking engagement, go to
their Facebook page, instagramor their webpage at
JacksonFamilyMinistrycom.
This podcast is produced byBobson Audio Production at
Bobsoncom.