In this special episode, host Jeremy Schrand sits down with Jill Brinck, Executive Director of CancerFree KIDS, and Dr. Genevieve Kendall, a CancerFree KIDS grant recipient and pediatric cancer researcher at Baylor College of Medicine.
Together, they explore the power of early-stage research funding, the challenges and breakthroughs in treating childhood cancers, and the inspiring mission behind CancerFree KIDS. Dr. Kendall shares insights into her lab’s work on fusion-driven rhabdomyosarcoma and how innovative models like transgenic zebrafish are helping uncover new therapeutic targets.
Whether you're a parent, a scientist, or someone passionate about making a difference, this episode offers a compelling look at how collaboration and curiosity are driving real change in pediatric oncology.
Learn more - CancerFree KIDS home page
Learn more about Dr Kendall’s research - Kendall Lab | Nationwide Children's Hospital
Learn more about CTI - CTI - CRO Specializing In Clinical Research And Consulting
02:03 Jill Brink shares her personal and professional journey that led her to become Executive Director of CancerFree KIDS.
04:02 Why funding early-stage, high-risk research is essential for pediatric cancer, highlighting the lack of profitability and federal support in this space.
05:46 Securing funding for early-stage research presents major challenges, including the need for collaboration between scientists and business leaders.
07:06 How CancerFree KIDS selects research projects, outlining the role of their Scientific Advisory Council and the grant scoring process.
09:26 Success stories driven by CancerFree KIDS funding, including early support for clinical trials and advancements in flash proton therapy.
11:22 Dr. Genevieve Kendall explains the nature of fusion-driven rhabdomyosarcoma and why its aggressive behavior and lack of targeted therapies make it difficult to treat.
13:51 How the CancerFree KIDS grant supported a new partnership and provided seed funding to test a promising research idea.
14:50 The significance of identifying HAS3 as a novel target and how it opens new possibilities for treating rhabdomyosarcoma.
16:35 Dr. Kendall describes the role of transgenic zebrafish in her research and how they help uncover therapeutic targets through comparative oncology.
19:33 Both guests share what excites them most about the future of pediatric cancer research, including innovations in CRISPR and immunotherapy.
22:32 How CancerFree KIDS measures the long-term impact of its grants, citing follow-up funding, startup companies, and FDA projects.
24:19 Jill highlights impactful partnerships and community initiatives, such as Jersey Mike’s Day of Giving and the 100-Mile Challenge.
26:15 Details about the 100-Mile Challenge, including its structure and supporting events throughout September.
27:51 How CancerFree KIDS engages with families affected by cancer, ranging from support programs to events that honor children and their journeys.
29:51 The future direction of CancerFree KIDS, including expansion, collaboration, and advocacy efforts with the state of Ohio.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
The Joe Rogan Experience
The official podcast of comedian Joe Rogan.