Neurology: Disease Deep Dive

Neurology: Disease Deep Dive

The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.

Episodes

Part II: Early Alzheimer Disease Detection through a Davos Alzheimer's Collaborative Initiative: Lessons from Real-World Implementation

June 12, 2026 • 19 mins
This episode explores the real-world implementation of the Davos Alzheimer’s Collaborative Healthcare System Preparedness (DAC-SP) US Early Detection Program at Virtua Health, examining outcomes in identifying cognitive impairment, streamlining referrals, and supporting efficient use of clinical resources. Elyse Perweiler, RN, MPP, Professor, Rowan–Virtua School of Osteopathic Medicine, Stratford, NJ, and Tim MacLeod, P...
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Part I: Early Alzheimer Disease Detection with the DAC-SP Blueprint Program: Overview of a Scalable Health System Approach

February 12, 2026 • 18 mins
Elyse Perweiler, RN, MPP, Professor, Rowan–Virtua School of Osteopathic Medicine, Stratford, NJ, and Tim MacLeod, PhD, Program Director, Healthcare System Preparedness Program, Davos Alzheimer’s Collaborative (DAC), Toronto, Ontario, Canada, examine how health systems can operationalize early cognitive screening to better prepare patients for specialty evaluation. Learn how standardized workflows, digital cognitive...
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Detecting Multiple Sclerosis Earlier: PRLs and the Evolving McDonald Diagnostic Criteria

December 15, 2025 • 29 mins
This episode explores new evidence showing that paramagnetic rim lesions (PRLs) are highly prevalent early in multiple sclerosis (MS) and can differentiate MS from mimics with striking accuracy. Dr. Daniel Ontaneda, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, and Dr. Pascal Sati, Cedars-Sinai Medical Center,  Los Angeles, CA, discuss how PRLs, paired with optimized susceptibility-based MRI, are reshaping diagno...
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Modern Glioma Management: Integrating Molecular Markers and New Targeted Therapies

December 3, 2025 • 13 mins
Patrick Y. Wen, MD, Dana-Farber Cancer Institute, Boston, MA, discusses current standards of care for low- and high-grade gliomas, including the importance of comprehensive molecular testing, the World Health Organization classification of tumors of the central nervous system, and newly available therapies.
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Maturing with Migraine: Practical Guidelines for Transitioning Adolescent Migraine and Headache Patients into Adult Practice

December 2, 2025 • 23 mins
Hope O’Brien, MD, MBA, FAHS, FAAN, Founder and CEO of the Headache Center of Hope, Cincinnati, OH, discusses challenges and considerations for adult headache neurologists who are onboarding adolescent patients as they transition from pediatric practice. Dr. O’Brien highlights a framework with strategies for a seamless transition, while noting best practices for promoting patient autonomy and mental wellbeing.
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Advances in ALS: New Targets, Trials, and Care Strategies

October 27, 2025 • 14 mins
Merit Cudkowicz, MD, Julieanne Professor of Neurology, Harvard Medical School, Boston, MA, discusses the evolving landscape of treatment for ALS, including FDA-approved disease-modifying therapies, the importance of genetic testing, the emergence of gene therapies, and the promising clinical trial pipeline targeting genetic and sporadic forms of ALS.
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Cerebrovascular Inflammatory Conditions: Diagnostic Challenges and Treatment Considerations

October 22, 2025 • 19 mins
Abbas Kharal, MD, MPH, Neurologist at Cleveland Clinic Neurological Institute, Cleveland, OH, provides a review of cerebrovascular inflammatory conditions, with an emphasis on diagnostic challenges, the evolving treatment landscape, and the use of imaging and clinical responses to assist clinicians with early detection and differentiation of these conditions.
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The Evolving Therapeutic Landscape for Parkinson Disease

June 6, 2025 • 20 mins
Mark Stacy, MD, William E. Murray Professor of Neurology, Medical University of South Carolina, Charleston, SC, discusses the evolving therapeutic landscape for Parkinson disease, highlighting promising advances in neuroprotective therapies, biomarkers, personalized medicine, and innovative clinical trial designs that aim to improve both treatment outcomes and accessibility.
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Advances in the Evaluation of TBI

June 4, 2024 • 20 mins
Welcome to Neurology: Disease Deep Dive. In this episode, Dr. Beth McQuiston, MD, RD, Medical Director at Abbott Laboratories, and Dr. David Okonkwo, MD, PhD, Professor of Neurological Surgery, Clinical Director of the Brain Trauma Research Center, and Director of the Neurotrauma Program at University of Pittsburgh Medical Center discuss evaluation and advances in evaluation of traumatic brain injury. Dr. McQuiston is talking with ...
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NMOSD Part 3 - Overview of treatment, including goals, triggers, and considerations for switching therapies

February 29, 2024 • 20 mins
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents an overview of NMOSD treatment, including goals, triggers, and considerations for switchi...
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NMOSD Part 2 - The importance and tools for monitoring NMOSD, and signs, symptoms and evaluation of disease activity

February 15, 2024 • 22 mins
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents the importance and tools for monitoring NMOSD, and signs, symptoms and evaluation of dise...
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NMOSD Part 1 - Overview and important considerations for diagnosis

February 1, 2024 • 31 mins
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents an overview of NMOSD, and important considerations for diagnosis. DA-UNBR-US-02294-2 05/2...
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Narcolepsy, Idiopathic Hypersomnia, and General Sleep Disorders

December 5, 2023 • 27 mins
In this episode, Rajkumar Dasgupta, MD, Clinical Associate Professor at Keck School of Medicine of USC and sleep specialist, provides an in-depth review of what's new in sleep disorders, with a special focus on updates in narcolepsy and idiopathic hypersomnia.
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