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September 8, 2025 39 mins

To answer this question, we speak with Dr. Alan Karthikesalingam and Vivek Natarajan from Google DeepMind about their groundbreaking AI co-scientist project. Beyond their work at Google, Alan is an honorary lecturer in vascular surgery at Imperial College London, and Vivek teaches at Harvard’s T.H. Chan School of Public Health. Together, we discuss how their system has evolved to mirror parts of human hypothesis generation while also diverging in fascinating ways. We talk about its internal “tournaments” of ideas, its ability to be prompted to “think out of the box,” and whether it becomes too constrained by the need to align with every published “fact”. And we discuss how we still seem far away from a time when AI can not only answer our questions, but can ask new and exciting research questions itself.

The Night Science Podcast is produced by the Night Science Institute – for more information on Night Science, visit night-science.org .

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