All Episodes

April 23, 2025 • 47 mins


In the final installment of our three-part ADHD series, we explore the real-world challenges and decision-making processes behind ADHD medication management in children. Dr. Gretchen Hoyle returns to guide us through:


đź§  Topics Covered

  • Medication combinations and why stimulants are often paired with alpha-2 agonists


  • How insurance formularies influence medication choices more than many parents realize


  • Age-specific prescribing, including alternatives for children who can't swallow pills


  • Navigating medication shortages and supply chain disruptions


  • The role of trial and error in ADHD medication—and how to manage it


  • Introducing genetic testing tools like GeneSight to guide personalized treatment


  • Managing co-occurring conditions such as anxiety and depression alongside ADHD


  • Importance of close monitoring, including questionnaires and side effect screening


  • Why collaborative care between families and physicians leads to the best outcomes


đź§Ş Mentioned in This Episode

  • GeneSight® – A pharmacogenomic test that analyzes how genes may affect medication response


  • Vanderbilt ADHD Diagnostic Rating Scales – Used to monitor symptoms and side effects


  • Alpha-2 agonists – Medications like guanfacine and clonidine, often used in combination with stimulants


📝 Key Takeaways

  • ADHD treatment is not one-size-fits-all; medication choice depends on medical, practical, and systemic factors


  • Parents play a critical role in observing and reporting how medications are affecting their child


  • While most children respond well to first-line medications, new tools like genetic testing can provide valuable insights—especially in complex cases


  • Regular follow-ups, screening tools, and open communication are essential to long-term success



📌 Resources

🔜 Next Up on Nimble Youth


We're launching a new series on Anxiety in Children:

  • Part 1: Anxiety in younger children

  • Part 2: The unique experience of teenage girls

  • Part 3: Addressing the growing crisis among adolescent boys


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