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March 7, 2025 34 mins

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive deep into Lymphoma, breaking down its pathogenesis, clinical presentation, and the latest advancements in treatment. We explore the key differences between Hodgkin and Non-Hodgkin Lymphoma, examining the role of Reed-Sternberg cells, CD markers, and genetic mutations that define these malignancies.

Our discussion includes high-yield diagnostic tools like lymph node biopsy, flow cytometry, PET/CT imaging, and molecular studies, helping you differentiate between indolent and aggressive subtypes. We also analyze cutting-edge treatments, including immunotherapy, targeted monoclonal antibodies (e.g., rituximab), chemotherapy regimens like R-CHOP, and the role of stem cell transplantation in refractory cases.

Additionally, we cover disease progression, prognostic factors, and complications such as tumor lysis syndrome and secondary malignancies. Whether you’re studying for boards, preparing for clinical rotations, or just love hematology-oncology, this episode is packed with high-yield pearls you don’t want to miss!

Enjoy the episode and support us below! 🔬🔥

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