It’s our first stats reunion! In this special review episode, we revisit favorite concepts from past episodes—p-values, multiple testing, regression adjustment—and give them fresh personalities as characters. Meet the seductive false positive, the clingy post hoc ex, and Charlotte, the well-meaning but overfitting idealist.
Statistical topics
- Bar charts vs Box plots
- Bonferroni correction
- Confounding
- False positives
- Multiple testing
- Multivariable regression
- Outcome switching
- Over-adjustment
- Post hoc analysis
- Pre-registration
- Residual confounding
- Statistical adjustment using regression
- Subgroup analysis
- Unmeasured confounding
References
- Nuzzo RL. The Box Plots Alternative for Visualizing Quantitative Data. PM R. 2016 Mar;8(3):268-72. doi: 10.1016/j.pmrj.2016.02.001. Epub 2016 Feb 15. PMID: 26892802.
- Sainani KL. The problem of multiple testing. PM R. 2009 Dec;1(12):1098-103. doi: 10.1016/j.pmrj.2009.10.004. PMID: 20006317.
Kristin and Regina’s online courses:
Demystifying Data: A Modern Approach to Statistical Understanding
Clinical Trials: Design, Strategy, and Analysis
Medical Statistics Certificate Program
Epidemiology and Clinical Research Graduate Certificate Program
Programs that we teach in:
Epidemiology and Clinical Research Graduate Certificate Program
Find us on:
Kristin - LinkedIn & Twitter/X
Regina - LinkedIn & ReginaNuzzo.com
- (00:00) - Intro
- (02:26) - Mailbag
- (06:42) - P-values
- (12:43) - Multiple Testing Guy
- (16:05) - Bonferroni solution
- (17:11) - Post hoc analysis ex
- (22:22) - Subgroup analysis person
- (30:28) - Statistical adjustment idealist
- (43:54) - Unmeasured confounding
- (45:19) - Residual confounding
- (49:25) - Over-adjustment
- (54:42) - Wrap-up
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