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October 17, 2024 • 48 mins

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Discover supplements for a sharper mind and healthier brain with Dr. Vanessa Pavey, a distinguished naturopathic doctor and education scientist from Life Extension. There is an alarming rise in memory-related concerns as our population ages; learn how Life Extension's Cognitex formula is poised to combat these challenges with groundbreaking ingredients like phosphatidylserine and vinpocetine. Dr. Pavey reveals the power of natural supplements, paving the way for innovative strategies in cognitive function support.

Hear about nootropics and explore the promising potential they hold for cognitive enhancement. Mango leaf extract takes center stage, showcasing its ability to clear brain fog and enhance mental performance. As we unravel the mysteries of nootropics, ingredients like gotu kola and bacopa emerge as stars in the domain of cognitive improvement. Dr. Pavey shares insights into the safety and efficacy of these components, affirming their benefits for all adults eager to boost their mental acuity.

Shift gears as we explore the intricate relationship between brain health and men's health. Dr. Pavey introduces Life Extension's Memory Protect, featuring colostrinin and lithium, designed to support cognitive longevity. The episode also delves into prostate health and male vascular support, offering practical solutions with products like the Ultra Prostate Formula and Male Vascular Sexual Support.

Use coupon code "NUTZ" (in your cart) for 15% off your entire order of featured products on our sponsor's website: HollyHillVitamins.com.

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Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Jim Wilk (00:00):
Welcome to Nutrition Nuts, where we explore
breakthroughs in nutritionscience, wellness trends and
dietary supplements.
You'll hear from industryleaders, health practitioners
and research scientists givingyou cutting-edge insights and
actionable tips for living yourhealthiest life.
I am your host and also headnut, jim Wilk, certified

(00:21):
nutritionist.
Thanks to our main sponsor,hollyllyhillvitaminscom, the

(00:42):
place for great selection,service and prices.
Okay, thank you so much forjoining us again today on
Nutrition Nuts.
I am your host, jim Wilk, andit's early fall.
What can I say?
It'sI love this time of year.

(01:03):
Love this time of year, love togo out hiking, love to look at
the different colors and thetrees and the earth and the sky
and everything.
It's a great, great time ofyear for me and I'm having on
today an old favorite, vanessaPavey.
Well, she's not old, but DrVanessa Pavey.
She's a naturopathic doctor andeducation scientist at Life

(01:24):
Extension, one of the premiercompanies out there that I
recommend and look forward totheir fantastic magazines and
get a lot of good information.
They have probably the mostmedical staff, most amount of
people doctors and naturopathson their staff than all the
other companies combined.

(01:44):
I think it's just not well.
They're just really intoextensive research and things,
so I like that.
They do a lot of good studiesand stuff.
So, vanessa, she enjoysdiscussing the mechanism of how
nutrition influences the bodyand is committed to improving
health through education.
That's what she does and sheactually was trained as a

(02:08):
primary care physician and shewas also very skilled in
biochemistry and she earned herbachelor of science degree in
biology from the University ofSt Francis before she started
training in naturopathicmedicine at Bastyr University in
naturopathic medicine at BastyrUniversity.
So she's been helping peopleand helping life extension
customers with learning moreabout the science of a healthier

(02:32):
life.
She's been doing this for over10 years there, so we appreciate
it.
Last time I had her on about afew years ago, it was vitamin K
we talked about and bloating anda lot of digestive stuff and
quercetin things.
So today I don't know what Ihaven't talked to her yet.
We haven't started the show yetwith her, obviously.
So I was going to bring upeither men's issues all right,

(02:55):
men have issues, just like otherhuman beings we're going to
discuss that and or brain stufftoo.
So some of it's connected rightguys.
It's that stuff that happensaround the bedroom.
They have a lot to do withwhat's going on in your head as
well, so I'm going to maybe tryto touch on both.

(03:16):
Some of the good products fromLife Extension and they have
some unique things for differentsituations.
So I wanted to make it clearfor people.
So it might be a good idea toget a pen and paper, as in the
old days kind of stuff, and seewhat Vanessa has to say.
She's fantastic, so you'llreally enjoy it.
And without further ado, hereis Dr Vanessa Pavey.

(03:37):
PavyDr Vanessa Pavey, thank you so
much for joining us.
It's been a few years.
You were on a few years ago.
I was looking back and wetalked about some stuff and I
got some new ideas I want todiscuss with you.
So how are you doing?
First of all, Everything good.

Dr. Vanessa Pavey (03:53):
I'm doing fantastic.
Thank you so much.
It's good to be back.

Jim Wilk (03:56):
Yeah, it's great.
And are you still in Las Vegas,or where am I reaching you now?

Dr. Vanessa Pavey (04:01):
Actually I am .
I'm still here in Las Vegaswith Life Extension.

Jim Wilk (04:06):
Yeah, okay, all right.
And does it get like fall there?
I've never been to Las Vegas inthe fall.
Do the buildings start turningcolors or what's going on?

Dr. Vanessa Pavey (04:18):
We do have a little bit of a fall.
The weather starts to get alittle bit cooler.
We don't have the beautifulweather that you guys have and
with all the trees turningcolors, but we do get a little
bit of that indication that theweather's changing.

Jim Wilk (04:32):
You would think that with all the technology, and
especially Las Vegas, they woulddo something to put some trees
up with different colors somehow.
You know, get that going there.
That would be so cool.
I mean, they do everything elsetechnology-wise there, so I'm
sure that's coming down the pikehere.
I don't know if you noticedsince we've talked last, which

(04:54):
was a couple of years ago, thatmore and more people are
interested in stuff to help withtheir memory and their brain.
There's that pallor going overthe earth here about are we
losing our minds, so to speak?
And dementia is becoming to theforefront and, of course,
alzheimer's and things.

(05:14):
And I guess we get every daysomebody asking about what can I
do to improve my memory?
And maybe it's because we, astime goes on, we have an older
generation that's lasting aroundlonger here and we wanted to
keep up with everything and keepour minds sharp.

(05:35):
So I know life extension and Itold the people how much
research you guys do.
This is not really mom and popkind of operation.
You guys go into good,extensive research and studies
and you have a fantastic medicalstaff there at Life Extension.
So I know you guys have a fewformulas and I'd like to go over

(05:56):
some of them, and you know,obviously, the ingredients in
them, because some of them are alittle unusual that I think the
public may not know about.
So I'd like to start maybe.
Well, one of your original oneswas the Cognitex, which is a
trademark, cognitex andcomprehensive support for brain
health.
So what are the some of the keyingredients in there is

(06:24):
phosphatidylserine andvinposantine, and wild blueberry
and ashwagandha, and the sageextract too, which is
interesting.
I don't think that many peoplethink of sage as far as the
brain goes.
So what was the genesis incoming out with this particular
formula?

Dr. Vanessa Pavey (06:39):
Oh, actually the genesis is that this was one
of our flagship products fromthe early 1980s when Life
Extension first startedlaunching supplements.
So Cognitex has been with LifeExtension for over 40 years at
this point and, of course, aseverything, life Extension does

(07:00):
upgrade and change the formulaat this time as new science
emerges.
So I might even argue that eachextract that you brought up is
the key ingredient.
Now, this is not the same kindof stage that you can get at the
grocery store or use in cooking.
This is actually a veryspecifically cultivated stage,

(07:22):
not a GMO, because I know whenpeople hear you're kind of
cultivated, that could give animplication of like GMO.
Now, this is not geneticallymodified what it is, it's
specifically hybrid and it isincredibly rich in the
rosmarinic acid, which is a keyingredient in sage that helps to

(07:45):
support memory, and how it doesthat is by slowing down the
enzyme that breaks down one ofour most important
memory-enhancingneurotransmitters, which is
acetylcholine.
So this enzyme breaksacetylcholine down and the
special stage slows that processdown.

Jim Wilk (08:07):
Ah, okay, and a lot of people are under the impression
they can buy acetylcholineright.
I've heard people ask for thatparticular ingredient.

Dr. Vanessa Pavey (08:15):
People can purchase like choline Usually,
like there are multipledifferent types of choline on
the market, like CDP choline.
Also, you can get choline fromyour phospholipids, like in
lecithin.
But in terms of acetylcholineitself, which is the
neurotransmitter, that acetylgroup does not necessarily stay

(08:37):
on the choline very long.
It's not actually ideal to takean acetylcholine because the
body needs to make it Right andit's consistently making and
breaking it down.
So it's actually more efficientto support body levels of
acetylcholine with a cholinetype of ingredient.

Jim Wilk (08:58):
Oh, interesting.
Okay, and the vinpocetine,which has been around a long
time as well, is a pretty cooltype of herb there.
That could also improvecognitive performance in people.

Dr. Vanessa Pavey (09:12):
There are studies showing that it does
help to support, specifically,concentration and memory.
And vimpocetine is a veryinteresting phytonutrient.
It is an alkaloid that'sderived from periwinkle so
purple French periwinkle plantand what it's really doing?
The mechanism behind it ishelping to support blood flow to

(09:33):
the brain, so this is a veryactually important ingredient
for helping to maintaincognition and memory as we age.
Now there is a caution forthose who are of childbearing
age or pregnant or planning onbecoming pregnant to maybe
consult with a doctor beforetaking periwinkle derivatives

(09:57):
like the venpostatine.
But other than that,venpostatine is a really great
option for those who are tryingto maintain their memory and
their cognitive function as theyage.

Jim Wilk (10:08):
Okay, another ingredient is phosphatidylserine
, which I remember from back inthe 80s.
Also, folks, you might haveseen PS.
They use those two lettersthere to indicate it's
phosphatidylserine.
But that's an old standby.
I mean it's still very populartoday.
Very good product, right?

(10:29):
A very good ingredient.
Excuse me, it is.

Dr. Vanessa Pavey (10:32):
I think a lot of people are pretty familiar
with phosphatidylserine or, likeyou said, like PS, for
supporting brain function,because it is a component of
cell membranes, specifically theneurons of the brain.
But another interestingmechanism behind the
phosphatidylserine is that italso works on the pituitary

(10:53):
level by blunting the amount ofACTH that's released from the
pituitary gland.
Now ACTH is adrenocorticotropichormone glans.
Now ACTH is adrenocorticotropichormone and what it does is it
tells the adrenal glands tocreate cortisol or stress
hormones.
So, fasted to the steering,helping to blend that process

(11:15):
can actually help modulate thestress response.
So it's also great, not justfor memory, but also helping to
keep us a little bit more coolduring the day, or even a great
way of supporting sleep at night, especially if stress helps
kind of keep you up at night.

Jim Wilk (11:29):
Cool beans.
Okay, so that was one of theiroriginal brain formulas.
Folks is Cognitex Elite, andthey make a few different kinds
of those.
The other one I wanted to talkabout too, is the brain fog
relief, and I know most peopleuse a cup of coffee for brain
fog relief, right, but thisparticular product has a mango

(11:51):
extract in there and somepeppermint oil, which is pretty
cool, because a lot of peopledon't think of like an essential
oil to take internally.
They use it for aromatherapy,and I know peppermint is very
like you know a little bit.
You put that in an aromatherapysituation.
It kind of wakes you up, so tospeak.
But you also use a mango leaf.

(12:12):
Well, I don't know, people lovemangoes.
They've been around forever, soI know the plant itself has
been used in traditionalmedicine and stuff for forever.
So talk a little bit about thepeppermint and the mango in this
brain fog relief product.

Dr. Vanessa Pavey (12:29):
Oh yeah, I'm glad you started with the
peppermint, because even justsmelling peppermint seems to
kind of wake up my senses andkind of give me a little bit
more clarity.
Really, when we take thepeppermint oil internally, what
we want are those monoterpenes.
These are the active componentsin peppermint oil that actually
improve the neurotransmittersthat are associated with memory

(12:53):
and attention, likeacetylcholine.
So monoterpenes in peppermintoil slow down the breakdown
again of acetylcholine, kind ofon par with the sage, because
even just sage peppermint, thesewonderful types of almost like
the ramieaceae family of herbs,have such a strong impact on

(13:16):
helping to support memory andfocus and concentration.
Peppermint also supports GABA,our calming neurotransmitter.
So that one was a must-have ina brain fog kind of formulation.
But I might argue, kind ofsimilar to the sage extract in
the Cognitex, that it's actuallythe mango leaf that's really

(13:39):
our shining star in this formula.
So it's not the mango fruitpart, it's actually the leaf.
And when I heard about it Ithought oh gosh, can people
consume the leaf?
I've never heard of that andactually I was completely wrong.
It's been used as a tea formany, many, many decades.
So Berry has an excellent safetyprofile and what the mango leaf

(14:02):
is rich in are polyphenols fileand what the main relief is
rich in are polyphenols, and itaddresses the three main targets
that we're trying to hit.
When somebody says brain fog,Because really brain fog is not
really technically a medicalterm, it's just kind of a
constellation of symptoms andusually those symptoms involve
like inflammation that canhappen in the brain, kind of

(14:23):
creating like a foggy feeling.
Histamine release is typicallyanother kind of target that
people say, oh you know, duringthose types of seasons where
pollen's in the air, people say,oh you know, I have a lot of
brain fog due to that, becauseof the histamine release.
And of course the third targetwould be like neurotransmitters,
but the third target would beneurotransmitters, specifically

(14:46):
the neurotransmitters likenorepinephrine, which is part of
focus and attention.
So what's really amazing aboutthe mango leaf extract is it

(15:08):
helps to modulate the enzymes,modulate the histamine response
and also helps to inhibit theexcess inflammation that can
happen and affect theneurological system.
So it's really a greatingredient if we're trying to
target all three components ofwhat can contribute to brain fog
.

Jim Wilk (15:18):
To clear your mind kind of thing.
I guess, if you're going to doa kind of a task or something
and you need to just concentrateon something, this just takes
the spiderwebs, so to speak Well, it's near Halloween,
spiderwebs away from the brainthere and just have a nice path
to go down.

Dr. Vanessa Pavey (15:38):
Absolutely.
I love that analogy, kind oflike clearing away the cobwebs,
right, because the studies thatLake Extension-Centrum was
looking at were actually lookingat cognitive performance rather
than just subjective measuresof well, how foggy do you feel?
Because that can be a littlebit more difficult to utilize in

(15:58):
a study.
So they were actually usingcognitive performance tests and
finding that those who weretaking either like the
peppermint oil, which was onestudy, or the mango leaf extract
, which was the second study thesubjects that took those
ingredients did perform betterseveral hours after consuming it

(16:19):
.
So this is something that wecan expect to have an impact
within the same day, just acouple hours after consuming,
because sometimes some of thenutrients do take a little bit
of time to help the healingprocess.
Sometimes we say, you know twoto three months, but this one is
one of those ingredients, ortwo ingredients, that work very

(16:39):
quickly.

Jim Wilk (16:41):
Yeah, that was my next question Because I seen some of
the studies and you see thesestudies usually for some of your
other products 15 weeks,something, you know, three
months, that kind of a thing.
So I have to remind the peopleout there that the natural stuff
sometimes takes a little longerthan maybe some pharmaceutical
thing, but the safety aspect istremendous in that.

(17:02):
So you've got to give thisstuff a little time.
I mean, most people haven'tlost their mind in overnight, so
you got to give this stuff alittle time.
I mean most people haven't losttheir mind in overnight, so
it's not going to come back thatquickly as easily.
So that's a good point to makeout there.
The next one I want to talkabout is quick Now we're talking
about time right, Quick brainnootropic.

Dr. Vanessa Pavey (17:25):
Explain to the folks what a nootropic is
and explain some of theseingredients, which are also
something I've seen for many,many years.
Yes, so nootropics have beenkind of making a splash in the
last couple of years, sometimesassociated with the terms like
biohacking or neurohacking.
So a nootropic is a little bitof a different ingredient than
something that we would use forhelping to support healthy

(17:46):
cognition with age.
A nootropic helps to enhancealertness, learning capacity,
focus, attention immediately,right then and there.
That's really kind of the gaugeof a nootropic is helping to
enhance cognitive abilities forall adults, whether you're 18

(18:09):
years of age or like 70 years ofage.
Trying to enhance thatcognitive kind of giving you a
little bit of an edge, I wouldmaybe say.
And now here's the caveat whenLife Extension was looking at
nootropics, we're all aboutsafety and what we wanted were
ingredients that have long-termsafety studies.

(18:31):
So these would be ingredientsthat it would be okay if you're
taking them on a daily basisover a long period of time.
So the ingredients that reallyshine in that category as
nootropics were gotu, kola,bacopa, and the one that
surprised me was lutein andzeaxanthin, which you usually

(18:53):
think of for eyes.
But the study that impressed methe most with the lutein and
zeaxanthin was actuallyconducted in college students,
which that's why I was prettysurprised, because I thought,
wow, these are usually collegestudents, they're already at the
top of their cognitive genes.
I thought, wow, these areusually college students,
they're already at the top oftheir cognitive genes, right.
So these students were givenlutein and diazanthin, or, of

(19:16):
course, the other group wasgiven a placebo.
Now they did take it for sixmonths because they wanted the
lutein and diazanthin to buildup, but then they had the
students come back and do justthis battery of cognitive tests,
had the students come back anddo just a battery of cognitive
tests and they found that thestudents that received the
lutein and the zeaxanthinactually outperformed not just

(19:37):
the placebo group butoutperformed their baseline
numbers.
So we were seeing someimprovement with that.
So it's not just for the eyes,it's also supportive of
cognition and could beconsidered.
Well, life extension isconsidering it a nootropic.

Jim Wilk (19:57):
Wow, that's really interesting.
I can see, wow, collegestudents use that because all
they're using now is Adderall, Ithink mostly.
So this would be somethinggreat to give to them.
Maybe it would help with someof the protest things going on
in the campus, I don't know.
But so this has the Marigoldand the picopa and the gotu kola
.
Marigold is also kind of alittle bit of unusual thing too,
right.

Dr. Vanessa Pavey (20:16):
Oh yeah, the marigold is really a fantastic
dietary source of not justlutein and zeaxanthin but also
mesozeaxanthin, which is nottypically found in our diet, and
humans need to actually makemesozeaxanthin from the lutein

(20:36):
we consume.
If we're looking specificallyat the eye which is great you
could actually kind of give anassessment of how many of these
important carotenoid pigmentslike lutein, zeaxanthin and
mesozeaxanthin that we have byactually looking at the macula
of the eye so your eye doctorcan help to assess that.
And half, like 50%, is supposedto be made up of lutein, 25% is

(21:02):
made up of mesozeaxanthin andthat last 25% is made up of
zeaxanthin.
So 25% of our maculose is madeup of mesozeaxanthin and we're
not getting it really from diet,unless you're eating marigolds,
because that's where we can getit.

Jim Wilk (21:17):
Yeah, wow, that's pretty cool.
But folks go tohollyhillvitaminscom mention
nuts and UTZ, our code, and get15% off the Life Extension
products we're talking abouttoday.
So we have the QuickBrainNootropic.
That sounds like a cool thing,something I might like to try
here, and it's just a one a day,which is nice there.

(21:40):
And again, they have thetrademarked ingredients.
Folks, I really look for thatwhen I look at products out
there.
If you see a nice littleasterisk near the product, it's
usually a trademark sign, acopyright sign showing that
there has been some research orsome studies done into it and
it's not somebody throwingsomething in from their garage,

(22:00):
right, right, vanessa, I meanthat happens out there.

Dr. Vanessa Pavey (22:04):
Oh gosh, yeah , Not at Lathic, it doesn't
happen with us.
No, no.

(22:25):
Yes, we do like to use yeah, no, actually the ingredient and
standardize what we're lookingfor.
But also, after it's put intolike either a pill or a capsule
or a tablet, we want to makesure that that potency is still
there.
So we'll always test thefinished product as well.
So lots of testing done at LifeExtension.

Jim Wilk (22:43):
Oh, definitely, folks.
That's why I recommend them.
Honestly.
I like that research that theydo there.
The next one is a dopamine, andI guess people get a little
confused when they see that worddopa and they're familiar with
dopamine and things like that Onthe bottle.
I'm looking at the bottle.
Dopamine supports mental acuityand longevity, and the main

(23:06):
ingredient in this product,folks, is wild green oat extract
, which again has become morepopular in the last few years.
So talk a little bit aboutdopamine.

Dr. Vanessa Pavey (23:17):
Yeah, that wild green oat extract.
And why that's important to say?
Because when I hear oats I'mthinking, oh well, if I just
have my oatmeal in the morningit'll be covered.
But actually it's the immaturegreen prior to maturity of the
oats that we eat for breakfastin the morning and it is
standardized to the isobitaxin.

(23:39):
That's the magic ingredient.
And we might even consider thiswild green oat extract a
nootropic as well, because whatit's doing is it's helping to
support, well, as the theproduct implies, dopa supports
dopamine and we also well,really dopamine, even though we

(24:00):
kind of think of it as thatfeel-good neurotransmitter
that's associated with, like thepleasure reward pathways of the
body, also vital for cognition.
And how this ingredientactually works is by slowing
down again the enzyme thatbreaks down dopamine.
We talked a lot about theenzyme that breaks down

(24:21):
acetylcholine, but now weOB.
This is the enzyme that breaksdown dopamine.
It has very little impact onthe other neurotransmitters.

(24:43):
It's really specific todopamine, which is why if we're
just targeting this one, wetypically don't have the
unwanted potential side effectsthat could arise if you're
targeting other MAO enzymes.

Jim Wilk (24:58):
Right, and this increases as one gets older, I'm
assuming.

Dr. Vanessa Pavey (25:02):
Absolutely.
Life Extension wrote a reallyfabulous article a couple years
ago talking about how this,specifically this aob enzyme,
increases with activity, likeyou said, uh, which is really
unnerving because, uh, you know,we're all about here at life
extension, as our name implies,you know, extending healthy
human life and supportinglongevity, and it's a little

(25:27):
unnerving to think that thelonger we live, the faster this
MAO-B enzyme starts to crank up,the less dopamine I have.
So this is why we putsupporting longevity, because
really we want to support thelongevity of our cognition and
our memory as well, and dopamineis a very big, important piece

(25:49):
of that.

Jim Wilk (25:50):
Yeah, sounds like a great product to achieve Wiz.
I wish you had all this stuffinto one product Big, giant
horse bill.
That would be fantastic.
But I can see the differentlevels and different avenues to
help with brain health, so it'sfascinating to me.
Dopamine looks like a greatproduct, folks, they also have

(26:13):
Memory Protect too, whichdefends against memory loss, and
that has an ingredientcolostrumin and lithium those
two ingredients Lithium alsoseems to be making a comeback.
I get people asking aboutlithium more often now than I
can't remember when come back.
I get people asking aboutlithium more often now than I

(26:34):
can't remember when.
So I think a lot of them getthem confused with the drug
lithium as well for people whouse for bipolar things.
So go into a little bit aboutthat.
This is a product called MemoryProtect from Life Extension.

Dr. Vanessa Pavey (26:43):
Oh, I'm glad that you brought up the lithium
and I do think there areconnotations with that in the
general public because, like yousaid, most people associate
lithium with the pharmaceutical,and really lithium is well, it
should be an essential tracemineral, but right now it's not

(27:06):
considered an essential one,which is why you don't normally
see lithium in your you knowlisting on your multivitamins
with the different minerals thatwe typically need to get, like
the magnesium and calcium andthings like that.
Right, correct.
In fact, the scientificcommunity is arguing that the

(27:26):
suggested daily requirement oflithium should be anywhere
between 1,000 to 2,000micrograms a day.
And I said micrograms, whichare really, yeah, that's a much
smaller dose than what would beconsidered like a milligram dose
, which is a little bit higherthan that.
That's where thepharmaceuticals come into play.
They're in milligram doses, inalmost gram doses, which are

(27:50):
even bigger doses.
So for a typical prescriptionof lithium it would be like 900
to 1800 milligrams a day.
So really that's almost likeone to two grams kind of an
estimate, which is a huge, hugeamount of lithium.

Jim Wilk (28:11):
Yeah, it'd be like taking 20 of these per day.
So yeah, I see what you'resaying one to two grams kind of
an estimate with a huge, hugeamount of lithium.

Dr. Vanessa Pavey (28:17):
Yeah, it'd be like taking 20 of these per day
.
So yeah, I see what you'resaying An extreme amount of
lithium, and where we typicallyget lithium in you know tiny
little trace amounts is reallyin water is where we're supposed
to.
I bet most of the listeners,like myself, are drinking
filtered water, like bottledwater, which actually does
filter out some of the lithium,so we're probably not getting as
much lithium as we think we arefor everyday health.

Jim Wilk (28:40):
Yeah, I didn't realize that.
And the colostronin also.
I read about it coming fromcolostrum, which is the first
milk produced after childbirthand most people think of that
for their immune system.
The mother giving some of thatimmune that first 40 hours of
breastfeeding.
When a baby is born ittransfers the immune system of

(29:01):
the mother to the baby.
So I found it pretty cool thatit also helps with brain
functioning.

Dr. Vanessa Pavey (29:08):
It does.
Isn't that fascinating howimmune and brain, the whole body
, is interconnected.
And the cholesterolspecifically.
It is kind of a complex ofpeptides.
It's really rich in proline andthere are studies showing that
it does enhance cognition,memory and mental function.

(29:32):
But here's what's kind ofinteresting the study that well,
actually several studies thatLife Extension were looking at
did not use colostrinin everyday.
They actually used it everyother day for two weeks and then
take a week off and then startoff again.
So it's a little bit of acomplex way of taking

(29:56):
cholesterol in.
Especially with busy lifestylesit's hard to kind of say, wait,
did I take it yesterday?
Did I have to take it everyother day?
But then, oh wait, has it beentwo weeks.
So what Life Extension did waswe put the pills in a blister
pack that's numbered by day.
We did the thing before you.
You just pop each day, you knowand go in order.

(30:18):
So you're kind of matching whatthey did in a study that gave
the best efficacy.
The other study that LifeExtension was looking at was the
lithium they were using.
Again, that's a small dose,that's 1000 micrograms a day,
but they were using that oneevery day.
So in the blister packs.
You're getting every daylithium and every other day
cholesterol in.

Jim Wilk (30:40):
Interesting.
Wow, that's so cool.
It's very rare you'd find thatin a supplement.
That kind of precision there.
That's pretty cool.
All right, folks, all right, yougot your memory down right.
You know where you have to be.
You know who you're talking to.
So we're going to switch overto some men's health.
You know, because I'm a man andI like to know and I know

(31:02):
Vanessa knows her stuff, so I'mgoing to be listening as well as
talking at the same time here.
So, vanessa, of course we haveto talk about at least my number
one selling life extensionproduct is the Ultra Prostate
Formula, and this is the one Irecommend to most of the men out

(31:22):
there when they're having someissues.
And over the years you guyswhich I love about you guys you
kind of change a few things, youadd a few things, more
knowledge comes out about thesethings, so you're always up on
what's going on.
That's why I love you guys.
So most prostate formulas havethe salt palmetto and the
stinging nettle and the pumpkinseed and things like that.

(31:44):
But you guys put some extrathings in there that I thought
were very beneficial.
So I'm sure you guys get goodreports back at the office there
about the prostate formula.

Dr. Vanessa Pavey (31:54):
We sure do.
In fact, this is our number oneselling product in the men's
health category and we havegotten probably more feedback
from this product than any otherone.
I mean, it really is awell-designed one.
Now, one of the feedback I doget sometimes outside of wow,

(32:15):
this has been really supportiveis the size of the soft gels.
The product is two soft gelserving size.
Please do make sure you'regetting the two soft gels daily
with food or, of course, isrecommended by your healthcare
practitioner.
But the reason why is becausethis is one of our
multi-ingredient formulas.

(32:37):
You might notice that LifeExtension doesn't do a lot of
formulas with multiple, multipleingredients like 10 or more
ingredients, because we're notabout just sprinkling a few.
You know, a milligram here andtwo milligrams there.
No, no, no.
We want to make sure that we'reproviding the same dose that
was used in the study thatprovided efficacy.

(33:00):
So unfortunately, that createswe're not skimping on dosing.
We're trying to minimize howmany pills you're consuming.
Unfortunately, that kind ofmakes for a larger softball.
So I really apologize.
I apologize in advance, butthat's the rationale for why.

Jim Wilk (33:16):
I got you.
I'd like you to talk about someof the unusual things.
And we also have a standalone.
One of the ingredients folks isflower pollen extract and you
guys also make a standaloneflower extract as well, the
prostopal and the triplestrength prostopal.
So we can kind of kill twobirds with one pill here and

(33:37):
talk a little bit about theflower pollen that's in the
prostate formula and your triplestrength prostopal.

Dr. Vanessa Pavey (33:42):
Great segue there, because sometimes when
people are looking at the labeland they see flower pollen
extract and it is from rye, somepeople might say, oh, you know,
will that have an impact on youknow?
Kind of the idea of you know, Idon't do well with pollen during
, you know, the pollen season.
Well, actually, what we do, thisspecific flower pollen extract

(34:06):
the part of the pollen thatcreates the problems during
those kinds of seasons is on theoutside.
It's the inside of the pollenthat has a really important
impact on supporting the healthof the prostate gland and
promoting healthy urinationpatterns.
There's some really nicestudies showing that it does

(34:27):
help to regulate healthyurination patterns, especially
at night, and helps to keepinflammation in check.
So it helps to inhibit theinflammatory response in that
prostate and urinary area.
So what we did for the ultraprostate formula was in the two

(34:48):
soft cell serving size there is63 milligrams of the flower
pollen extract, which is theideal daily dose.
But for those who are havingtrouble, like, for example,
especially getting up multipletimes during the night, that can
be really problematic for thenext day if you're not getting
good sleep.
We did add what we call thetriple strength to toss the

(35:13):
pollen out from the rye and it'sproviding 378 milligrams in one
soft gel.

Jim Wilk (35:19):
so this was specifically designed to pair
with the ultra prostate formulaI didn't even realize that, and
so I'm glad you pointed that out.
Yes, it can be used with the.
Uh yeah, excellent, that's agreat, great idea.
So I know a lot of guys whatthey say, like when you hit 70
or so, about 75, 80% of the menout there have problems at night

(35:43):
and to enlarge prostate orprostatitis and things like that
.
So this is interesting.
I might add that to my mixthere as well.
And again, it's a trademarkedGraminix is your patented or
flower extract.
So again, you're using stuffthat's been scientifically
looked at or studied right.

Dr. Vanessa Pavey (36:03):
Right and it's consistent in its
standardization.
So the Graminix flower pollenextract and ultra prostate
formula is standardized to 7%phytosterols, again from rye, so
really great ingredient,especially for supporting
healthy urination patterns.
But there's some otheringredients that help also

(36:25):
target inflammation and healthyurination patterns in terms of
the prostate arena, like forexample, a standardized extract
of Boswellia, which we callAprafl hygeum, which is also
known as African cherry tree, sothat one is a bark extract

(36:45):
which also helps to keepinflammation and healthy
urination patterns going, andsome additional phospholipids
that pair really nicely withpumpkin seed extract.

Jim Wilk (36:56):
Okay, and you also have the lycopene in there as
well.
That's becoming a little scarceout there.
I've noticed the lycopene.
Do you know anything about thatat all?

Dr. Vanessa Pavey (37:06):
Oh, it's really a potent antioxidant, and
Y-Life Extension added it tothis specific product.
Now, of course, women canbenefit from lycopene too, but
there's really nice researchshowing that it helps to support
healthy prostate size andhealthy prostate function.
Now the interesting thing aboutlycopene is that we are

(37:26):
deriving it from tomato extract,and just eating tomatoes may
not be the best way of gettingyour lycopene, because actually
the lycopene is concentrated intomatoes when they're cooked
down almost into like a tomatopaste.
So a plug for adding a littlebit of tomato paste to your

(37:47):
tomato sauce is to get a littleextra lycopene.
But for daily intake it'sprobably a good idea to add the
lycopene to aprostate-supporting formula.

Jim Wilk (37:57):
Of course, and I see that the ultra-prostate formula
also has the pumpkin seed oil inthere and Life Extension also
makes a standalone just foradded support, kind of does what
, maybe in the same vein as—thatwasn't a pun— in the same vein
as the prostapollin helps withurinary functions and things

(38:18):
like that Same vein, as theprostapollin helps with urinary
functions and things like that.

Dr. Vanessa Pavey (38:27):
The pumpkin seed oil specifically does have
an impact on prostate health,but the studies did show that it
supports prostate health whenit's complemented or added with
cell palmetto, so making surethat you're getting them
together Now.
The flower pollen extract canwork as a standalone all by
itself right when you're doingpumpkin seed oil, you might want
to consider making sure thatyou're getting some of those
like beta-cetosterols that arefrom salt palmetto and even

(38:51):
kaijam, to really have thefull-on effect for prostate
health.

Jim Wilk (38:56):
Good to know.
Okay, all right, folks, we gottwo more here I'd like to
discuss, and againhollyhillvitaminscom and look up
some of these great productsfrom Life Extension.
It's worth it Mention Nuts andUTZ and get 15% off our already
low prices on that.
So that's why we do this.
We do a show, so you guys learnmore about the stuff just as

(39:19):
well as I'm learning all thetime and you make your buying
decisions more prudent there.
So the last two I want to talkabout is the male vascular
sexual support, and I've gottena lot of good feedback on this
product.
Vanessa, this is a one a day,folks.
It's a special trademarked formof black ginger and I'm just

(39:41):
getting good feedback.
I can't really explain how itworks to people, but I know
people are coming back andsaying this does a job here and
you know, give it a little time,it's really a good support for
men.

Dr. Vanessa Pavey (39:54):
This is another one.
I would say this is probablythe second in the men's category
that we get the most feedbackon and it is a type of ginger,
but not the typical ginger youget at the grocery store.
It's actually Thai black gingerthat's been used historically.
It's native to Southeast Asiaand it's been used historically
to support and enhance malesexual health, and it does so on

(40:17):
several different pathways.
First, it helps promote nitricoxide synthesis, which helps to
support the blood vesseldilation, to get more blood flow
to the area.
It also helps to relax theblood vessels and, of course,
enhance the blood flow and therewas actually a study that also

(40:38):
showed that it has a potentialimpact on neurotransmitters to
help the brain respond a littlebit more quickly to sexual
stimuli.
And really the underlying kindof mechanism, especially for
supporting, like nitric oxideand healthy blood flow, is that
it does help to slow down one ofthe enzymes that winds down the

(41:01):
malsexual response.
So if we inhibit this enzyme itkeeps that malsexual response
going longer.
And what's really nice nowwe're not going to see, probably
, effects in the first day likewe would see with a nootropic or
the quick brain, but this onewe would see, with consistent
use results seen after 30 days.

(41:22):
So taking, you know, taking itevery day for a month, that's
when we're really going to startseeing things kind of balance
out in the body and having amore robust sexual response yeah
, folks.

Jim Wilk (41:33):
So if you're, you know , looking for, like a natural
alternative, some of the viagrasand things out there which can
have some side effects, I meanmean it's still a possibility.
There's been heart issues,vision issues with Viagra, so
this might be a good alternativeto try, but give it that 30 to
45 days to really start seeingsomething.
And just I know men have toldme that it really does a great

(41:54):
job for that.
All right, that's the malevascular sexual support, and the
last one I'd like to talk aboutis the testosterone elite.
I think a lot of guys maybeVanessa worry too much about
their testosterone.
They feel like they should haveit without them getting
themselves tested, and what I'vealways read is that you can
have high testosterone levelsand feel crappy and vice versa.

(42:18):
Right, and it's a good idea,and I know Life Extension does
fantastic testing.
I always get my blood work donethrough Life Extension because
they offer a lot more than whatyour general practitioner can
offer and they will actually sitdown with you, the medical
staff, and go over things overthe phone with you.
So testosterone elite has somepomegranate in it, which has

(42:39):
always been known to help withthose kind of levels, so this is
supposed to promote free andtotal testosterone right.

Dr. Vanessa Pavey (42:47):
Correct and I'm so glad you brought that up
about the lab testing.
I think it's so importantbecause if you're looking at
just free testosterone or totaltestosterone, you might be
missing a bigger picture ofbalance in the body.
Men also need to test estrogenBecause, like you said,
sometimes the testosterone is upbut you still feel a little bit

(43:07):
off.
Well, testosterone can beturned into estrogen.
So if you have a lot oftestosterone, it might be
turning into a lot of estrogen,Specifically that potent form
called estradiol.
So when we're testing it'sreally important to get the big
picture, looking at testosterone, estrogen and maybe even the
precursors to testosterone likeDHEA, and also looking at

(43:31):
prostate health too, so kind ofgetting a full round picture.
Life Extension offers a panelcalled the Male Basic Hormone
Panel that measures DHEA,sulfate free and total
testosterone, estradiol and PSA.
You're getting your fullspectrum of what could be
happening.
But I'm also glad that youbrought up the pomegranate,

(43:52):
because when I first saw theproposal of this product I
thought pomegranate, Could thatreally have an impact on
testosterone?
And yes, it can.
In fact there was a study withboth men and women who were just
taking pomegranate juice andtheir saliva.

(44:14):
They tested saliva testosteroneand everyone's testosterone
went up with pomegranate.
Of course, men are going tohave higher levels of
testosterone go up because ofthe fact that men tend to have
more testosterone.
So this really is a formula thatwas designed to be almost like
an herbal approach forsupporting the natural
production of testosterone.

(44:36):
So it's not providing anyhormones per se, but what it's
doing is it's helping the bodyto produce the maximum that it
can, and we do have clinicaldata showing that it does
support both free and totaltestosterone.
But we also added anotheringredient to help balance that
estrogen piece of the puzzle,and that is the luteolin.

(44:57):
Luteolin is found in multipleplants like, for example, like
parsley and cilantro.
We're extracting it from theJapanese sephora flower, and
what luteolin does is it slowsdown the enzyme that converts
testosterone into estrogen, andsome men are familiar with this
enzyme.
It's called aromatase, so mendon't need too much aromatase

(45:21):
activity.
So the luteolin was a reallygreat addition to the formula to
keep that under control.

Jim Wilk (45:27):
Wow, and that's found in plants and stuff.
The luteolin right, it's ingreen broccoli and stuff like
that.

Dr. Vanessa Pavey (45:34):
Yeah, the richest source in terms of the
vegetables would be celery.
Like that, yeah, the richestsource in terms of the
vegetables would be celery.
But if you're really wanting toget luteolin, having your
parsley salad like tabbouleh canbe a really rich source of your
luteolin.

Jim Wilk (45:47):
Yeah, and you throw a little cocoa in there.
Right, cocoa there, a littlechocolate never hurt anybody,
right.

Dr. Vanessa Pavey (45:53):
We did, actually, and it's standardized
to the theobromine found in theraw cacao and I was kind of
wondering.
You know we're talkingpomegranate and chocolate, so if
I eat a, chocolate bar withsome pomegranate in there.
Am I covering my basis?
Well, honestly, probably not tothe extent that we probably

(46:15):
need this particularstandardization of the
pomegranate and the cacao arevery concentrated, specifically
the prunicalagins in thepomegranate and the field
bromine.
I wouldn't discourage anyonefrom enjoying some chocolate,
but make sure it's not too muchsugar, because I would imagine
that would probably have anegative impact not just on
hormone status but just overallhealth.

Jim Wilk (46:37):
Yeah, folks, they're extracting the good ingredients
out of those products and plantsand things and concentrating a
little bit so you don't have tosit there and eat 10
pomegranates at once there.
So I can appreciate that.
Great stuff Again, folks theUltra Prostate Formula for Men,
the Triple Strength Prostapolin,the Male Vascular Sexual

(46:57):
Support and the TestosteroneElite, as well as all the great
products from Life Extension.
You can go to lifeextensioncom.
You get a lot more information,their magazine.
I've always depended on theirmagazine for information and
what's happening in the news Alot of times.
Vanessa, I'll start the showhere with some articles from
Life Extension and latestresearch on certain things,

(47:21):
latest studies on certainingredients.
So you guys still do a greatjob and I always appreciate you
being on and the other expertsat Life Extension.
It makes my job a lot easier.
So thank you so much for beingon today.

Dr. Vanessa Pavey (47:35):
Thanks for having me.
It was a lot of fun yeah it wasa lot of fun.

Jim Wilk (47:38):
We'll do it again, folks.
I promise Vanessa's got awealth of wisdom out there and
we're going to tap it as much aswe can, so we'll talk to you
guys real soon.
Take care everybody.
Please subscribe to the channelso you can get our latest
episodes, and if you want tocontact me with any questions or
comments, try jimwilkcnc atgmailcom.

(48:00):
Thanks again.
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